RFQ.pdf

Solicitation No. 75N95024Q00440

Title: High-Performance Liquid Chromatography (HPLC) with integrated flow through radiation detector.

i. This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a separate written solicitation will not be issued.

ii. This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13—Simplified Acquisition Procedures; and FAR Part 12—Acquisition of Commercial Items and is not expected to exceed the simplified acquisition threshold. A fixed-price type of purchase order is contemplated for this requirement.

iii. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2024-03, with effective date 05/02/24.

iv. The North American Industry Classification System (NAICS) code for this procurement is 334516 – Analytical Laboratory Instrument Manufacturing and the small business size standard is 1,000 employees. This requirement is full and open with no set-aside restrictions.

v. The purpose of this requirement is to provide NIDA with a High-Performance Liquid Chromatography (HPLC) with integrated flow through radiation detector.

The Government requires one brand name or equal High-Performance Liquid Chromatography (HPLC) with integrated flow through radiation detector to measure arterial plasma concentrations of injected radioligands in studies involving human participants. A Capable Offeror must demonstrate its ability to provide the following brand name or equal items and Salient Characteristics to the Government:

Product No. Description Qty.

DL-241-04 Logi-CHROM - Stainless Steel Quaternary pump (with degasser) 862 bar max pressure. Includes: - Quaternary Low Pressure Gradient stainless steel pump - 4 channel degasser - Piston seal wash - 200 μl mixer

DL-241-03 Logi-CHROM - Stainless Steel Isocratic pump (with degasser) and solvent selection valve 862 bar max pressure. Includes: - Isocratic pump - 10 mL stainless steel pump head - 2 channel degasser - Piston back flush and LAN cable - 1 channel solvent selection valve

MISC 10 Port Valve, C/W Valve Controller 2 DL-241-35 Logi-CHROM Column Thermostat

Microprocessor controlled Peltier element for heating and cooling, fan supported 2-way air circulation. Temperature range 5 - 85°C

DL-241-36 Mounting bracket for Logi-CHROM valve drive. (QTY 2 required with every setup) Both-sided, conductivity monitor left sided.

DL-241-09 Logi-CHROM Manual 6 Port 2 Position Valve.

Logi-CHROM Manual injector, 6 Ports, 1200 bar max pressure.

DL-241-12 Mounting Bracket For Manual Injection Valves 1 DL-241-10 Sample loop 100 μl stainless steel

Stainless steel, 1/16", ID 0.45 mm

DL-241-50 VariLoop, 40mL, 1/16" Logi-CHROM VariLoop L 1/16" stainless steel volume up to 40mL

DL-241-51 Mounting bracket VariLoop Mounting bracket for prep sample loop

DL-241-25 Logi-CHROM UVD - Without Flow Cell With deuterium lamp without flow cell.

DL-241-26 Stainless Steel Flow cell for Logi-CHROM UV - 10 mm 10 μl.

Stainless steel, with heat exchanger one sided inlet and outlet.

DL-241-02 Logi-CHROM - Solvent Bottles 4 x 1000 mL bottles and 1 x 250 mL bottle for piston backflushing.

DL-241-01 Logi-CHROM - Eluent tray 1 DL-241-32 Logi-CHROM tool kit

Tool kit for PEEK/pre-cut capillary kits

DL-241-44 Logi-CHROM Analytical StartUp kit Standard, 0.25 mm ID, Set of 1/16" capillaries, adapters and connectors

PI-JXX-04 Posi-RAM PET Metabolite Detector with Laura Radiopharma Software Flow-through radio-Isotope Positron/Gamma Detector including Laura radio-chromatography control and data analysis software. Software Features • Direct control of the instrument by Laura Software • Powerful data analysis and reporting • Includes DBO mode for enhanced security Flow-through radio-Isotope Positron/Gamma Detector Standard built-in features include: • Continuous-Flow Coincidence Positron/Gamma Counter • Two High Efficiency 1” photomultiplier tube with BGO crystal

PI-JXX-02 Flow-cell for Posi-RAM (Please specify volume, 250ul maximum)

P1F-6XX-508 Flow cell with built in point source - Disc Casing Na-22, 1μCi - 37,000 Bq Source type 0.5" laminated disk. This source has been calibrated using a HPGe detector whose efficiency was established with the NIST traceable mixed nuclide standard SRS: 80899-854. The stated activity is the weighted average of the measured gamma lines with an estimated uncertainty of 5%. The source is of sealed construction and wipe tested for surface contamination prior to shipping.

L-CE-AH-32 Laura Software HPLC System Control Option HPLC system instrument control includes regression analysis. Needs to be installed on the same PC as the Base License

GL-Z1XX-59 2-day Installation & Familiarization 1 PL-YXX-100 Laura for Logi-CHROM HPLC - Annual Software Support

Contract Includes: • Priority response • Unlimited access to our technical support team and help desk • Access to the customer support area • Free upgrades within major version • Software development requests given priority

PL-L4-07 Laura Radiopharma/Posi-RAM- Annual Software Support Contract Starting from the date of installation. Includes:

• Priority response

• Unlimited access to our technical support team and help desk

• Access to the customer support area

• Free upgrades within major version

• Software development requests given priority

MISC Warranty on all parts and labor Warranty in place for 12 months after installation or 15 months after shipment – whichever comes first.

P3G-36XX-01 Windows 11 Desktop PC with Monitor Windows 11 OS, minimum 16GB RAM, minimum Intel i5

Processor, minimum 22" Monitor

Optional items:

PL-YXX-100 Laura for Logi-CHROM HPLC - Annual Software Support Contract (up to 4 additional years) Includes: • Priority response • Unlimited access to our technical support team and help desk • Access to the customer support area • Free upgrades within major version • Software development requests given priority

PL-L4-07 Laura Radiopharma/Posi-RAM- Annual Software Support Contract (up to 4 additional years) Starting from the date of installation. Includes:

• Priority response

• Unlimited access to our technical support team and help desk

• Access to the customer support area

• Free upgrades within major version

• Software development requests given priority

PL-YXX-107 Posi-RAM - Annual Service Contract – Hardware (up to 4 additional years) Starting from the end of the warranty period. Includes:

• Priority response

• Unlimited call outs for repairs

• Annual preventative maintenance visit with proactive scheduling

• All parts, labor and expenses included

• Remote technical support

• Full engineer report Performance verification following repairs

• Refresher user training

MISC Logi-CHROM - Annual Service Contract – Hardware (up to 4 additional years) Starting from the end of the warranty period. Includes:

• Priority response

• Unlimited call outs for repairs

• Annual preventative maintenance visit with proactive scheduling

• All parts, labor and expenses included

• Remote technical support

• Full engineer report

• Performance verification following repairs

• Refresher user training

vi. Delivery shall be made 60 days after the award date. Delivery shall be made to the following:

NIH

49 Convent Dr.

Building 49, Room B1A59 Bethesda, MD 20982

vii. The provision at FAR Clause 52.212-1 Instructions to Offerors—Commercial Items is applicable to this solicitation. Also, the full text of a solicitation provision may be accessed electronically at these addresses:

https://www.acquisition.gov/browse/index/far https://www.hhs.gov/grants/contracts/contract-policies-regulations/hhsar/index.html

viii. The provision at FAR Clause 52.212-2, Evaluation-Commercial Items (Nov 2021) applies to this acquisition. The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered.

Selection of an offeror for contract award will be based on an evaluation of proposals against three factors. The factors are: Technical, Past Performance, and Price.

Although technical factors are of paramount consideration in the award of the contract, price and past performance are also important to the overall contract award decision.

All evaluation factors other than price, when combined, are significantly more important than price. The Government intends to make an award to that offeror whose proposal provides the best overall value to the Government.

The evaluation will be based on the demonstrated capabilities of the prospective Contractors in relation to the needs of the project as set forth in the SOLICITATION.

The merits of each proposal will be evaluated carefully. Each proposal must document the feasibility of successful implementation of the requirements of the SOLICITATION.

Offerors must submit information sufficient to evaluate their proposals based on the detailed factors listed below.

The evaluation factors are used when reviewing the proposals.

1. Technical Capability and Functionality

NIDA shall evaluate the offeror’s technical approach for overall capability and functionality in relation to the General Requirement, Salient Characteristics, Quantities and Deliverables.

2. Past Performance

Offerors will be evaluated based on information obtained from references provided by the offeror, other relevant past performance information obtained from other sources known to the Government, and any information supplied by the offeror concerning problems encountered on the identified contracts and corrective action taken.

Furthermore, the Government will assess the relative risks associated with each offeror. Performance risks are those associated with an offeror's likelihood of success https://www.acquisition.gov/browse/index/far https://www.hhs.gov/grants/contracts/contract-policies-regulations/hhsar/index.html in performing the acquisition requirements as indicated by that offeror's record of past performance. The assessment of performance risk is not intended to be the product of a mechanical or mathematical analysis of an offeror's performance on a list of contracts but rather the product of subjective judgment by the Government after it considers all available and relevant information.

3. Price

Offerors price quote will be evaluated for reasonableness. For a price to be reasonable, it must represent a price to the government that a prudent person would pay when consideration is given to prices in the market. Normally, price reasonableness is established through adequate price competition, but may also be determined through cost and price analysis techniques.

Offerors may respond with a proposal indicating their ability to provide the technical specifications stated in this solicitation. Responses will be evaluated based on the contractor’s ability to meet the Government’s requirements.

Evaluation of Options

It is anticipated the award from this RFQ will contain option provision(s) and period(s).

In accordance with FAR Clause 52.217-5, Evaluation of Options, (July 1990), the Government will evaluate offers for award purposes by adding the total price for all options to the total price for the basic requirement, except when it is determined in accordance with FAR 17.206(b) not to be in the Government's best interests.

Evaluation of options will not obligate the Government to exercise the option(s).

ix. FAR clause 52.217-7 Option for Increased Quantity—Separately Priced Line Item (Mar 1989). The Government may require the delivery of the numbered line item, identified in the Schedule as an option item, in the quantity and at the price stated in the Schedule. The Contracting Officer may exercise the option by written notice to the Contractor within 5 days of the expiration date of the order. Delivery of added items shall continue at the same rate that like items are called for under the task order, unless the parties otherwise agree. (End of clause)

x. FAR clause 52.217-9 Option to Extend the Term of the Contract (Mar 2000).

The Government may extend the term of this order by written notice to the Contractor any time prior to order expiration; provided that the Government gives the Contractor a preliminary written notice of its intent to extend at least 5 days before the order expires. The preliminary notice does not commit the Government to an extension. If the Government exercises this option, the extended task order shall be considered to include this option clause. The total duration of this task order, including the exercise of any options under this clause, shall not exceed 5 years. (End of clause)

xi. The provision at FAR Clause 52.212-3, Offeror Representations and Certifications Commercial Items, applies to this acquisition.

xii. The provision at FAR Clause 52.212-4, Contract Terms and Conditions—Commercial Items, (with NIH Invoice and Payment Provisions) applies to this acquisition. See Attachment 1.

xiii. The provision of FAR Clause 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items, applies to this acquisition. See Attachment 2.

xiv. Responses must include the place of manufacturing (i.e. address if supply/equipment is a domestic end product and include country of manufacture). For equipment/supply requirements, small businesses must also address the size status of the manufacturer under the applicable NAICS code (i.e. address Non-Manufacturer Rule). In case domestic sources are available and capable of fulfilling the Government’s need the Government will use evaluation preferences in accordance with FAR 25.

xv. There are no additional contract requirement(s) or terms and conditions applicable to this acquisition.

xvi. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement.

xvii. Responses to this solicitation must include sufficient information to establish the interested parties’ bona-fide capabilities of providing the product or service. Responses to this solicitation must include clear and convincing evidence of the Offeror’s capability of fulfilling the requirement as it relates to the government requirements stated in this solicitation.

Basic cost and price information in the Offeror’s proposal must contain sufficient information to allow the Government to perform a basic analysis of the reasonableness of the Offeror to supply the required goods/services. Any other information or factors that may be considered in the award decision may include such factors as: past performance; trade-in considerations; warranty considerations; maintenance and service coverage availability;

serial, product or catalog number(s); product description; delivery terms, and prompt payment discount terms.

The Contractor shall submit its quote electronically to polina.klimenkova@nih.gov

In addition, the vendor Unique Entity Identifier (UEI) and the certification of business size must be included in the response. All Offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.”

All responses must be received no later than August 5th, 2024, 8:00 pm EST. Late responses will not be accepted. All responses must reference solicitation number 75N95024Q00440. For information regarding this solicitation, please contact Polina Klimenkova by email at polina.klimenkova@nih.gov.

http://www.sam.gov/ mailto:polina.klimenkova@nih.gov

xii. The provision at FAR Clause 52.212-4, Contract Terms and Conditions—Commercial Items, (with NIH Invoice and Payment Provisions) applies to this acquisition. See Attachment 1.