RFI Data Matrix.xlsx
XLSX spreadsheet 28 KB Posted
- Attached to
- Real World Data – Data Sources, Platforms, and Services Federal contract opportunity
- Solicitation number
- 75N992-25-SS-102
About this file
This document is a Request for Information (RFI) from the Department of Health and Human Services' National Institutes of Health (NIH) on behalf of the Advanced Research Projects Agency for Health (ARPA-H). ARPA-H is seeking information from vendors capable of providing real world data (RWD) to support its mission, including data sources, data management and analytics platforms, data management and curation services, and project management.
The RFI outlines ARPA-H's specific data requirements, such as longitudinal electronic medical record, claims, pharmacy, and laboratory/diagnostic data for over 100 million persons with a minimum 90-day refresh rate. ARPA-H also requires demographic, socioeconomic, educational, nutritional, pollution, healthcare access, and weather/climate data at the ZIP3 level. The RFI asks vendors to provide capability statements addressing ARPA-H's needs in four key areas: data sourcing, data management and analytics platforms, data management and curation services, and project management. Vendors are requested to include information on data set availability, refresh rates, estimated annual costs, and other relevant details.
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Other files for this federal contract opportunity
| File | Type | Posted |
|---|---|---|
| 75N992-25-SS-102 Sources Sought Notice.pdf | ||
| 75N992-25-SS-102 Need Summary.pdf |
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Text version
United States Data Requirements
| Vendor Name | |||||
| Vendor UEI: | |||||
| ARPA-H Requirement | Vendor Response | ||||
| Data Description | Population | Refresh Rate | Has Data Set (Y/N)? | Brief Description of Dataset Meeting Requirements | Estimated Annual Cost |
| Longitudinal (>5 years) Electronic Medical Record data | >100 million persons | Minimum of 90-day refresh | |||
| Longitudinal (>5 years) medical claims data | >100 million persons | Minimum of 90-day refresh | |||
| Longitudinal (>5 years) pharmacy claims data | >100 million persons | Minimum of 90-day refresh | |||
| Longitudinal (>5 years) laboratory and diagnostic data (genetic testing, diagnostic imaging, etc.) | >50 million persons | 90-day refresh | |||
| Demographic data at the ZIP3 | >100 million persons | N/A | |||
| Socio-economic data at the ZIP3 | >100 million persons | Minimum of 180-day refresh | |||
| Educational access at the ZIP3 | >100 million persons | Minimum of 180-day refresh | |||
| Nutritional access at the ZIP3 | >100 million persons | Of 180-day refresh | |||
| Pollution and/or environmental exposure data at the ZIP3 level | Entire United States | N/A |
| Data regarding a person’s access to healthcare ZIP3 level | Entire United States | N/A |
| Longitudinal weather and climate data at the ZIP3 | Entire United States | N/A |
Clinical trial participation data and results >100 trials N/A
Observational study data >1,000 participants per study N/A
International Data Requirements
| Vendor Name | 0 | ||||
| Vendor UEI: | 0 | ||||
| ARPA-H Requirement | Vendor Response | ||||
| Data Description | Population | Refresh Rate | Has Data Set (Y/N)? | Brief Description of Dataset Meeting Requirements | Estimated Annual Cost |
| Longitudinal (>5 years) Electronic Medical Record data | >100 million persons | Minimum of 90-day refresh | |||
| Longitudinal (>5 years) medical claims data | >100 million persons | Minimum of 90-day refresh | |||
| Longitudinal (>5 years) pharmacy claims data | >100 million persons | Minimum of 90-day refresh | |||
| Longitudinal (>5 years) laboratory and diagnostic data (genetic testing, diagnostic imaging, etc.) | >50 million persons | 90-day refresh | |||
| Demographic data at the ZIP3 | >100 million persons | N/A | |||
| Socio-economic data at the ZIP3 | >100 million persons | Minimum of 180-day refresh | |||
| Educational access at the ZIP3 | >100 million persons | Minimum of 180-day refresh | |||
| Nutritional access at the ZIP3 | >100 million persons | Of 180-day refresh | |||
| Pollution and/or environmental exposure data at the ZIP3 level | Entire United States | N/A |
| Data regarding a person’s access to healthcare ZIP3 level | Entire United States | N/A |
| Longitudinal weather and climate data at the ZIP3 | Entire United States | N/A |
Clinical trial participation data and results >100 trials N/A
Observational study data >1,000 participants per study N/A
Platform Req Rev.
| Vendor Name | 0 | ||||
| Vendor UEI: | 0 | ||||
| ARPA-H Requirement | Vendor Response | ||||
| High Level Requirement | Requirement | Specific Capability | Has Capability (Y/N) | Brief Description of Capability Meeting Requirements | Estimated Annual Cost |
| Biostatistical Platform | Basic Platform for biostatistical analysis | ||||
| Statistical Software Packages | SAS | ||||
| STATA | |||||
| SPSS | |||||
| R | |||||
| Other | |||||
| Genomic Platform | Basic Platform for -omics data and metadata | ||||
| -omics data analysis capabilities | DNA Sequencing (Single-cell or bulk) | ||||
| RNA Sequencing (single-cell or bulk) | |||||
| Long-read sequencing | |||||
| LC-MS/MS or other proteomic assays | |||||
| Metabolomics | |||||
| DNA structural analysis (Hi-C, ATAC, etc.) | |||||
| DNA methylation analysis | |||||
| Imaging Platform | Basic Platform for biomedical image data managment and analysis | ||||
| Radiographic Analysis | X-Ray | ||||
| CT | |||||
| PET | |||||
| MRI | |||||
| Other | |||||
| Light Based | Wide-field | ||||
| Flourescence | |||||
| Confocal | |||||
| NIR | |||||
| Other | |||||
| Viewing and annotation capabilities | |||||
| Scalable batch processing of DICOM s or other image stacks with metadata | |||||
| Notebook Platform | Basic Platform for writing, executing, managing notebook scripts | ||||
| Supported Notebook Scripts | JupyterLabs | ||||
| R Studio | |||||
| Other | |||||
| Supported Languages | Python | ||||
| R | |||||
| PERL | |||||
| Java | |||||
| Julia | |||||
| bash | |||||
| Other | |||||
| Architecture Capabilities | Multiple Enclaves | 20-30 Initial Enclaves, scalable to 200 (long term) | |||
| Program Specific Enclaves | Program Specific Website/Front Door | ||||
| Storage/Access for Program Specific Data | |||||
| Storage/Access for Program Analytical Tools | |||||
| Flexibile for performance from 6 months to 5 years | |||||
| Interactive Analysis Applications | (e.g. R Shiny, Dash, etc.) | ||||
| Artificial Intelligence (Ai)& Machine Learning (ML) | Support for Ai/ML Workflows | ||||
| Download Management | Ability to Download Data | ||||
| Ability to prohibit/limit downloading of data | |||||
| Individual Sandboxes | Space for individuals to manage their data and analyses | ||||
| Abilitity to limit & share acess to these spaces | |||||
| Warehouse Integration | Ability to integrate with warehouse services (e.g. AWS Redshift, Google Data Flow, Azure Stream Analytics) | ||||
| Federal IT Requirements | FedRAMP Certified | ||||
| Section 508 Compliance | |||||
| Low-code reproducible workflows based on program specific needs | CWL | ||||
| WDL | |||||
| SnakeMake | |||||
| NextFlow | |||||
| Other | |||||
| Biomedical data API support | FHIR | ||||
| GA4GH | |||||
| DRS | |||||
| Passports | |||||
| WES | |||||
| Other |
Sheet1
| Has Data Sets |
| Yes |
| No |
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