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This is a Notice of Funding Opportunity (NOFO) from the Department of Health and Human Services National Institutes of Health seeking applications for a Leadership and Coordination Center (LACC) for the MACS/WIHS Combined Cohort Study (MWCCS). The grant (RFA-HL-26-011) will support a 6-year project period (2026-2032) to continue epidemiological research on approximately 5,600 middle-aged and older people living with HIV (PLWH) and comparable individuals without HIV. The NOFO runs parallel with two companion U01 opportunities: RFA-HL-26-009 for Clinical Research Sites and RFA-HL-26-010 for a Data Analysis and Sharing Center.

The study employs a "populomics" approach examining health determinants across multiple scales including molecular, cellular, physiological, behavioral, environmental, and sociopolitical factors. The funding is available to a wide range of applicants including higher education institutions, nonprofits, small businesses, tribal organizations, and government entities. The grant is supported through multiple NIH research programs including those focused on women's health, lung diseases, cardiovascular diseases, cancer prevention, mental health, alcohol research, drug use, infectious diseases, minority health, aging, and sleep disorders research.

RFA-HL-26-011 Full Announcement Text

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