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This is a Request for Applications (RFA) announcement from the Department of Health and Human Services National Institutes of Health focused on advancing complementary and integrative health approaches for maternal health outcomes. The funding opportunity (RFA-AT-25-002) is a limited competition R01 grant specifically for investigators currently funded through the NIH IMPROVE Initiative, with emphasis on Maternal Health Centers of Excellence partnering with complementary and integrative health experts.

The grant requires applicants to propose a multisite feasibility clinical trial that will inform future full-scale clinical trials on mind and body interventions for maternal health. Key objectives include assessing intervention fidelity across sites, demonstrating recruitment and randomization feasibility, evaluating participant adherence and retention, and testing data collection protocols. The opportunity is supported by multiple NIH programs including the Office of Research on Women's Health (93.313), Mental Health Research Grants (93.242), Child Health and Human Development Extramural Research (93.865), and Research and Training in Complementary and Integrative Health (93.213). Eligible applicants are limited to public higher education institutions currently involved in the IMPROVE initiative.

RFA-AT-25-002 Full Announcement Text

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