REVISED SOW 6.21.docx

OSTATEMENT OF WORK

Humphrey Per Diem

1.0 GENERAL INFORMATION

1.1 Title of Project: Dr. Humphrey – (BLRD- Biomedical Laboratory Research and Development) and (CSRD- Clinical Sciences Research and Development) (BCCMA- BLRD and CSRD Collaborative Merit Review Award): Targeting Osteoarthritis Pain and Progression: Preclinical OA models of vagal nerve stimulation to reduce pain and progression

1.2 Background: Oklahoma City VA HCS Research Department requires a service contract to provide per diem Animal Housing at the OMRF Animal Facility which includes care & housing of VA Research animals.

1.3 Associated References/Policies

1.3.1 Guide For The Care And Use Of Laboratory Animal

1.3.2 PHS Policy On Humane And Care And Use Of Laboratory Animals

1.3.3 VA Directive 1200.07

1.3.4 Memorandum of Agreement (MOA) Between the Oklahoma Medical Research Foundation (OMRF) and the Oklahoma City VA Health Care System (OKCVA)

2.0 Scope of Work: The contractor shall provide the following:

2.1. VA to pay per diem costs incurred to provide care, housing of VA research animals and their safety in compliance with regulatory requirements below:

2.1.1 Daily health checks on every animal

2.1.2 Health reports and reminders prepared for Dr. Humphrey and completed by the OMRF comparative medicine staff

2.1.3 Veterinary health care

2.1.4 Routine veterinary treatments for ailing animals

2.1.5 PPE

2.1.6 Standard daily maintenance diet and water (per Associated References/Policies in 1.3)

2.1.7 Standard caging and ancillary equipment

2.1.8 Complete cage change on a frequency determined by cage type and per diem (per Associated References/Policies in 1.3)

2.1.9 Cage washing/assembly/autoclaving of standard cages and accessories

2.1.10 Cage change hoods cleaned, certified, maintained (per compliance with Associated References/Policies in 1.3)

2.1.11 Environmental monitoring (per facility SOPs )

2.1.12 Environmental enrichment

2.1.13 Facility maintenance and sanitation

2.1.14 Large equipment maintained (cage washer, autoclaves, etc.)

2.1.15 Refuse disposal (soiled bedding and carcasses)

2.1.16 Preventative health care and routine serology (per Associated References/Policies in 1.3)

2.1.17 Husbandry supplies (mops, disinfectant)

2.1.18 Training – surgical techniques, common procedures, etc.

2.1.19 Security

2.1.20 Provide cages (per Associated References/Policies in 1.3)

2.1.21 Housing needs are required to ensure the general health of animals is safeguarded and that undue stress is avoided, with appropriate attention paid to environmental factors such as temperature, ventilation, humidity and cleanliness.

2.1.22 The Veterinarian Medical Officer shall provide fresh and contaminant free feeding/nourishment as many times a day as the norm for each species.

2.2 The government shall

2.2.1 Provide the mice

2.2.2 VA Research Admin/Dr. Humphrey will request approval and verify with OMRF Animal Resources that they have adequate space and cages to house the mice prior to purchasing the animals. Dr. Humphrey is estimating roughly 40 cages.

2.2.3 Provide Quality Control

2.2.3.1 Veterinarian Medical Officer is responsible for overseeing the quality of care provided and housing facility are fully in compliance with regulatory requirements. Factors included for quality control are defined in 2.1 of this document. Daily census will be maintained and provided to the government for verification of billing costs

2.2.3.2 Oklahoma City VA Medical Center Research and Development programs administer VA Research Grants which have been approved for the use of animals for Research. All VA animal care and use programs are accredited by the Association for Assessment and Accreditation of Laboratory Animal Care International Review of daily inventory of animal census will be reviewed prior to approval of monthly invoices approved for payment.

3.0 Other Requirements

3.1 Security

3.1.1 Oklahoma Medical Research Foundation shall establish and implement methods of making sure all keys/key cards issued for entrance into their animal facility are not lost or misplaced and are not used by unauthorized persons. NOTE: All references to keys include key cards.

3.2 Place of Performance: The work to be performed under this contract will be performed at Oklahoma Medical Research Foundation, 825 NE 13th Street, Oklahoma City, OK 73104

3.3 Period of Performance:

Period of Performance shall be 3 years:

Base Yr: 10/01/24 - 09/30/25 Option Yr 1: 10/01/25 - 09/30/26 Option Yr 2: 10/01/26 - 09/30/27

3.4 Hours of Work: As per the OMRF’s work schedule.

3.5 CONTRACT AWARD MEETING: The Contractor shall not commence performance on this contract until the Government has conducted a contract kickoff meeting, post-award conference or the Government POC has advised the Contractor that a kickoff meeting is waived.

3.6 Misc The Government shall not exercise any supervision or control over the contract service providers performing the services herein. The contract service providers shall be accountable solely to the Contractor who, in turn, is responsible to the Government.

3.7 Deliverables Schedule:

3.8 Project Management Plan

3.8.1 The Contractor shall prepare a detailed Project Management Plan (PMP). For every task, the Contractor shall identify in writing all necessary subtasks (if any), associated costs by tasks, and associated dates.

3.8.2 All written deliverables shall be phrased in layperson language. Statistical and other technical terminology shall not be used without providing a glossary of terms.

3.8.3The Government shall complete their review of draft deliverables within 5 business days from date of receipt. The Contractor shall have 5 business days to deliver the final deliverable from date of receipt of the government’s comments.

3.9 Contractor Personnel Requirements

The Contractor shall provide personnel capable of performing for successful accomplishment of the work to be performed under this contract. Additionally, all personnel shall pass a Government specified background investigation prior to working with Personally Identifiable Information. The position sensitivity for this effort has been designated as Low Risk and the level of background investigation is a National Agency Check with Written Inquiries. All personnel shall be U.S. Citizens. The Contractor will coordinate with the COR for all Security Issues.

3.10 Security Requirement

To protect the Government’s intellectual property, confidentiality and public knowledge of the contract Subsection H is included. It defines the contract requirements for all intellectual property, release of information, the release of public relations and marketing materials and the requirement that all Contractor personnel to sign non-disclosure statements.

3.11 Confidentiality And Nondisclosure

It is agreed that:

1. The preliminary and final deliverables and all associated working papers, electronic files, course materials and reports, and other material deemed relevant by the Government which have been generated by the Contractor in the performance of this task order are the exclusive property of the U.S. Government and shall be submitted to the Contracting Officer at the conclusion of the contract.

2. The Contracting Officer will be the sole authorized official to release verbally or in writing, any data, the draft deliverables, the final deliverables, or any other written or printed materials pertaining to this task order. There shall be no information released by the Contractor. Any request for information relating to this contract presented to the Contractor shall be submitted to the Contracting Officer for response.

3. Press releases, marketing material or any other printed or electronic documentation related to this project, shall not be publicized without the written approval of the Contracting Officer.

4. All selected Contractor personnel assigned to work on this project shall be required to sign a non-disclosure statement regarding key aspects of the project and project content. (Keep it if applicable)

3.12 Compliance With Applicable Laws And Regulations

The Contractor shall ensure that services provided to the Government under this agreement comply with all applicable laws, statutes, regulations, and guidelines that govern the operation of systems by the Government. The Contractor shall also ensure that all services provided to the Government under this agreement comply with all Government mandated procedures, standards, and requirements.

As the Government develops and implements new or modified policies and procedures either to comply with internal agency rules and procedures or to comply with applicable rules, regulations, statutes, or other binding obligations ("Additional Compliance Terms"), the Government reserves the right to incorporate such Additional Compliance Terms into this Agreement. The Contractor hereby acknowledges and agrees that such Additional Compliance Terms shall become part of this agreement. The Government shall provide the Contractor with prior written notice regarding the date by which the Contractor shall comply with each set of Additional Compliance Terms ("Compliance Date"). Failure to comply with the Additional Compliance Terms prior to the Compliance Date shall be cause for the Government to immediately terminate this agreement. In the event that the Government terminates this agreement because of the Contractor's failure to comply with Additional Compliance Terms by the Compliance Date, the Contractor shall be liable for such reasonable costs as may be associated with the Government’s efforts to procure a replacement Contractor and associated systems and services.