PWS_IDEXX.doc

Performance Work Statement (PWS)

Blood Smear Sample Analysis Services 13 August 2024 C.1 Background:

The Special Projects Team (SPT) of the Biological & Biotechnology Sciences (BBS) Division requires the collaboration with IDEXX for blood sample analysis in support of a top priority project of Dr. Baker. IDEXX Reference Laboratory offers a wide variety of sample analysis for veterinary and research settings.

C.2 Objective:

The objective of this effort is to conduct complete blood count and lymphocyte analysis on our blood samples, with all results verified by a certified pathologist.

C.3 Requirements:

C.3.1 The Contractor shall complete the following sample analysis services for classification of Lymphocyte Morphology on a Blood Smear:

C.3.1.1 Routine Staining of Blood Smear:

· Preparation and staining of blood smear samples to facilitate microscopic examination.

· Anticipated to be 1000 samples in the base year, and 650 samples for option year one (1) (reference paragraph C.9.1).

C.3.1.2 Microscopy:

· Examination of the stained blood smear by an American College of Veterinary Pathologist (ACVP)-certified clinical pathologist.

· Classification of lymphocytes into two (2) categories:

· Unremarkable: Lymphocytes with scant clear cytoplasm, a clumped chromatin pattern, and no visible nucleolus.

· Reactive or Atypical: Lymphocytes with morphology that deviates from "unremarkable" criteria, as described above.

· Notation of any lymphocytes exhibiting very unusual morphology.

C.3.1.3 Exclusions: The following analyses and assessments are not included in this service:

· Standard five-part differential leukocyte count

· Assessment of the erythron

· Assessment of the platelet mass and morphology

· Data interpretation beyond the classification of lymphocytes C.3.1.4 Calibration and Consultation:

· An initial pilot study for calibration between the Principal Investigator (PI) and the IDEXX clinical pathologist is recommended to ensure consistency and accuracy in the classification of lymphocytes.

· Consultation services for this calibration study are complementary and will be provided at no additional cost.

This detailed scope ensures that the specific needs for lymphocyte classification are met, while also providing a pathway for consistent and accurate results through the recommended calibration study.

C.3.2 The Contractor shall provide further consultation services (anticipated 40 hours per year base and option year one (1)) related to the experimental data sets, including (reference paragraph C.9.2):

· Interpretation of the data

· Biological and toxicological significance

· Descriptive statistics

· Correlation with clinical observations and anatomic pathology findings C.4 Non-Personal Services:

ARL/ALC/GARRISON NON-PERSONAL SERVICES (JUL 2012)

The contractor, as an independent contractor and not as an agent of the Government, shall provide the necessary resources (except those furnished by the Government) to accomplish tasks of the type set forth in the PWS.

Contractor employees performing services under this contract shall be controlled, directed and always supervised by management personnel of the contractor. The contractor's management shall ensure that employees properly comply with the performance standards outlined in this PWS and as required by the contracting officer or the TPOC. Contractor employees shall perform independent of and without the supervision of any Government official. Actions of contractor employees may not be interpreted or implemented in any manner that results in any contractor employee creating or modifying Federal policy, obligating the appropriated funds of the U.S. Government, overseeing the work of Federal employees, providing direct personal services to any Federal employee or otherwise violating the prohibitions set forth in Parts 7.5 and 37.1 of the Federal Acquisition Regulation (FAR). The Government shall control access to the facility and shall perform the inspection and acceptance of completed work and tasks.

C.5 Place of Performance:

The blood smear sample analysis services required under this contract will be performed at the following location: Attn: Sample Receiving, IDEXX BioAnalytics, 2825 KOVR Drive, West Sacramento, CA 95605.

C.6. Period of Performance:

The period of performance of this contract will commence on 10 September 2024 and conclude on 09 September 2026. The performance period is anticipated to be 12-months, including the base period and any option periods if exercised.

Base Period

· Start Date: 10 September 2024

· End Date: 09 September 2025 Option Periods The Government reserves the right to extend the term of the contract by exercising option periods. Each option period will have a duration of 12-months.

Option Period 1:

· Start Date: 10 September 2025

· End Date: 09 September 2026 C.7 Distribution Statement:

C.7.1 Distribution Statement A applicable to this PWS and any technical data/documentation generated during performance: Approved for public release; distribution is unlimited.

C.8 Anti-Terrorism (AT) – Operations Security (OPSEC) Requirements:

The following AT-OPSEC requirements apply: Not Applicable

C. 9 Deliverables:

The Government plans to send a batch on blood smear samples to IDEXX monthly. Upon each review, the Government requires a report showing the contractor’s findings. The requirements of this report are outlined in paragraph C.3 of this PWS.

All deliverables outlined in the PWS shall be completed and submitted in accordance with the timeline specified in the DD1423 located within Section J of the contract. Any deviations from the schedule shall be approved in writing by the Contracting Officer (KO).

C. 9.1 The Contractor is to perform Blood Smear Sample Analysis services on the samples provided by the Government monthly. This service includes (1) routine staining of a blood smear and (2) microscopy.

C. 9.2 The Contractor is to perform further consultation services pertaining to the experimental data sets, including interpretation of the data, biological and toxicological significance, descriptive statistics, correlation with clinical observations and anatomic pathology findings.

Contracting Officer: