Purchase Description.pdf

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DNA Extractor
Solicitation number
75N95025P00064
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This document is a Purchase Description for a DNA Extractor solicitation issued by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health. The solicitation seeks to acquire a Maxwell RSC System (part no. AS4500) for the Center for Alzheimer's Disease and Related Dementias, specifically to support neurodegenerative disease research through high-throughput DNA extraction. The required instrument must have capabilities including automated nucleic acid purification from various sample types, processing 1-16 samples per run, integration with a liquid handler, and include a Quantus Fluorimeter.

The solicitation (No. 75N95025P00064) is a combined synopsis/solicitation for a commercial item under simplified acquisition procedures, with a NAICS code of 334516 and a small business size standard of 1,000 employees. Quotes are due by March 24, 2025 at 12:00 pm Eastern Time, submitted electronically to Andrea Clay. The government anticipates a firm fixed-price purchase order with delivery within 30 days of order receipt to 9000 Rockville Pike, Bethesda, MD. Evaluation will consider technical capability, past performance, and price, with technical and past performance weighted more significantly than price.

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Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

1. Statement of Need and Purpose: This acquisition is necessary for the preparation and high through-put processing of samples for targeted resequencing of DNA to support neurodegenerative disease research within the Center for Alzheimer’s Disease and Related Dementias.

2. Background Information and Objective: The Center for Alzheimer’s Disease and

Related Dementias (CARD) works to understand the pathological basis of neurodegenerative diseases. The purpose of this acquisition is to provide an instrument for high throughput DNA extraction of patient samples.

3. Generic Name of Product: DNA Extractor

4. Purchase Description: Maxwell® RSC System, part no: AS4500, QTY: 1

5. Salient characteristics All deliverables required under this contract shall be packaged, marked and shipped in accordance with Government specifications. At a minimum, all deliverables shall be marked with the contract number and Contractor name. The Contractor shall guarantee that all required materials shall be delivered in immediate usable and acceptable condition.

DNA Extractor System shall include:

• Automated purification of nucleic acids from blood, serum, plasma, viral transport media, cells, swabs, and saliva suitable for use in PCR and NGS applications

• Automated purification of nucleic acids from formalin fixed and paraffin embedded (FFPE} tissue samples for in vitro diagnostic applications

• Ability to perform automated nucleic acid extraction in either an in vitro diagnostic or research use operating mode

• Purification method that uses sample lysis and binding to paramagnetic particles as the primary separation principle

• Utilization of a low elution volume (LEV) format for sample processing allowing for maximum nucleic acid concentration

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

• Automated processing of 1 to 16 samples per purification run with run times between 23- 70 minutes

• Heated elution to improve yields

• Pre-filled reagent cartridges

• Pre-loaded extraction protocols for each type of starting material

• Quantus"' Fluorimeter for quantification of nucleic acids and proteins

• Integration with Liquid Handler for automated pre- and post-extraction sample preparation

• A footprint size no larger than 13” by 14”

• Portal software for seamless passing of sample tracking data from one instrument module to the next

Quantity: 1

6. Delivery Date: Delivery date of 30 days after receipt of completed purchase order

File details come from the government source that posted it. Updated .