Purchase Description.pdf

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NUcleic acid Linked Immuno-Sandwich Assay Reagents
Solicitation number
75N95025Q00065
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This is a Purchase Description and related RFQ for NUcleic acid Linked Immuno-Sandwich Assay Reagents required by the Center for Alzheimer's Disease and Related Dementias (CARD) at the National Institutes of Health. The requirement is specifically for 30 units of Alamar NULISAseq Inflammation Panel 250, #800103, which will be used for biomarker discovery to support neurodegenerative disease research.

The RFQ (75N95025Q00065) has a response deadline of January 22, 2025 at 12:00 PM ET, with delivery required within 90 days after receipt of order to Bethesda, MD. The requirement falls under NAICS code 325413 with a size standard of 1,250 employees. The government anticipates a firm-fixed-price purchase order award. Key technical requirements include the ability to provide multiplexed analysis of over 250 proteins from 10uL samples, attomolar sensitivity with >95% detectability for specific cytokines, and a 12-log dynamic range without dilution. Quotes must include unit price, shipping costs, delivery terms, and product specifications. Responses must be submitted electronically to Andrea Clay at the provided email address.

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Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

1. Statement of Need and Purpose: This acquisition is necessary for biomarker discovery to support neurodegenerative disease research within the Center for Alzheimer’s Disease and Related Dementias.

2. Background Information and Objective:

The Center for Alzheimer’s Disease and Related Dementias (CARD) works to understand the pathological basis of neurodegenerative diseases. The purpose of this acquisition is to provide NUcleic acid Linked Immuno-Sandwich Assay reagents to analyze cellular proteomics which will detect and quantify biomarkers related to ADRD

3. Generic Name of Product: NUcleic acid Linked Immuno-Sandwich Assay Reagents

4. Purchase Description:

Alamar NULISAseq Inflammation Panel 250, #800103

5. Qty 30

6. Salient characteristics All deliverables required under this contract shall be packaged, marked and shipped in accordance with Government specifications. At a minimum, all deliverables shall be marked with the contract number and Contractor name. The Contractor shall guarantee that all required materials shall be delivered in immediate usable and acceptable condition.

NUcleic acid Linked Immuno-Sandwich Assay REAGENTS must be able to provide the following features:

• Provides highly sensitive, multiplexed analysis of more than 250 proteins from as little as 10uL of sample

• Provides attomolar sensitivity (low fg/mL) and >95% detectability for analysis of critical, low abundance proteins/cytokines such as IL4, IL5, IL17, IL30, IL33.

• Ability to measure protein changes across a broad range of biological expression levels with up to 12 logs dynamic range in a single sample without dilution

• Provides highly reproducible assays with median CVs <10%

• Compatible with ARGO proteomics platform.

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

7. Delivery Date: 3 months after receipt of purchase order

File details come from the government source that posted it. Updated .