PURCHASE DESCRIPTION Automated Cell Dissociation Apparatus.pdf
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- SOURCES SOUGHT: Automated Cell Dissociation Apparatus Federal contract opportunity
- Solicitation number
- 75N95025Q00116
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This is a Purchase Description and related Sources Sought notice for an automated cell dissociation apparatus required by the National Institute on Aging (NIA), Laboratory of Neurogenetics. The requirement specifically calls for an S2 Genomics Singulator 100 Cell Dissociation Platform (PART# 100067764) for single nuclei isolation from human and mouse brain tissues, to support research on neurodegenerative diseases including ALS, Parkinson's, and Alzheimer's.
The equipment must be bench-top compatible, use single-use cartridges, and provide reproducible tissue dissociations into single-cell or nuclei suspensions. Key requirements include pre-set protocols, ability to process various cell types from rat/mouse/human tissues, and customizable software parameters. The Sources Sought notice, due January 17, 2025 at 3:00 PM ET, seeks responses from qualified small businesses to determine appropriate acquisition method and set-aside potential. Responses must be submitted electronically to Rashiid Cummins at NIH, limited to 10 pages, and include capability statements addressing technical requirements, company size status, and manufacturing location details. Delivery is required within 60 days post-award.
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Version 11-30-2016-1 FAR Part 11—Describing Agency Needs
PURCHASE DESCRIPTION
1. Statement of Need and Purpose: The National Institute on Aging (NIA), Laboratory of Neurogenetics (LNG) requires the acquisition of an automated cell dissociation apparatus for single nuclei isolation from human and mouse brain tissues.
2. Background Information and Objective: The National Institute on Aging, Laboratory of
Neurogenetics’ objective is to elucidate the pathological basis of neurodegenerative diseases, specifically amyotrophic lateral sclerosis (ALS), Parkinson's disease, and Alzheimer's disease. The purpose of obtaining an automated cell dissociation apparatus is for single nuclei isolation from frozen human and mouse brain tissue with the goal of future single cell snRNA sequencing.
3. Generic Name of Product: Automated Cell Dissociation Apparatus
4. Purchase Description: S2 Genomics Singulator 100 Cell Dissociation Platform (PART# 100067764)
5. Salient characteristics:
Must be able to fit easily on the bench-top Must employ single-use cartridges Enable reproducible, and rapid tissue dissociations into single-cell or nuclei suspensions Must provide a variety of pre-set protocols and pre-formulated reagents for cell nuclei isolations Must be able to reliably process a variety of cell types from a wide range of tissue sources (rat, mouse and human) Platform methodology must circumvent lengthy centrifugation processes Software supporting the platform must be able to support customizable parameters to include mincing, enzyme incubation times, temperatures, mixing and mechanical disruption profiles
6. Quantity: One (1)
7. Delivery Date: 60 days post award
8. Period of Performance: N/A
9. Option(s): N/A
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