Presolicitation_Notice_75N95024R00013_2.pdf

Pre-Solicitation Notice

Notice No. 75N95024R00013

Project Title: The NIH National NeuroHIV Tissue Consortium – New Clinical Site

THIS IS NOT A REQUEST FOR PROPOSALS (RFP). THIS IS A PRE- SOLICITATION

ANNOUNCEMENT ONLY. A REQUEST FOR PROPOSALS WILL BE ISSUED VIA

SAM.GOV ON OR ABOUT 15 DAYS FROM THE DATE OF THIS ANNOUNCMENT (ON

OR ABOUT FEBRUARY 26, 2024).

Description

The National Institute of Mental Health (NIMH) intends to solicit proposals from qualified businesses (NAICS Code 541715) to establish a new National NeuroHIV Tissue Consortium (NNTC) clinical site as a critical resource for catalyzing high priority research in NeuroHIV, including studies to understand the mechanisms of HIV neuropathogenesis, aging with long-term HIV and ART, and research towards an HIV cure. The NNTC shall collect, store, and provide clinical data and well characterized biological specimens, including post-mortem tissue from study volunteers and/or organ donors with HIV as well as HIV-negative controls. It is anticipated that a single contract for a new clinical site will be established from the solicitation.

The National Institute of Mental Health (NIMH), the National Institute of Neurological Disorders and Stroke (NINDS), the National Institute of Drug Abuse (NIDA), and the National Institute on Aging (NIA) seek to continue to support the collection and distribution of central nervous system (CNS) and peripheral nervous system (PNS) biospecimens and antemortem clinical data for research on NeuroHIV.

The objective of this initiative is to establish a new clinical site to provide access to antemortem and postmortem central nervous system (CNS) and peripheral nervous system (PNS) biospecimens as well as antemortem clinical data for research on NeuroHIV, including data from HIV negative controls. The objectives also include facilitating proactive involvement with the HIV advocacy and patient communities, efficiently and effectively acquiring, processing, characterizing, curating, storing, and distributing biospecimens for research with the ultimate goal of better understanding the heterogeneity of CNS complications in people with HIV and reducing the burden of NeuroHIV specifically as well as other consequences of HIV more broadly.

This contract is to establish a new clinical site for the National NeuroHIV Tissue Consortium (NNTC). The NNTC Clinical Site will function as part of the NNTC, a national research resource that provides clinical data, biological specimens, and postmortem tissues to NeuroHIV investigators interested in conducting research on Human Immunodeficiency Virus (HIV) associated CNS co-morbidities in the context of anti-retroviral therapy (ART), as well as investigators who are advancing efforts towards a cure for HIV.

Statement of Work: Please see attached draft Statement of Work.

Notice:

This requirement will be procured using full and open competition procedures under FAR Part 15.

The Government anticipates a single award with a potential period of performance of five (5) years.

The anticipated contract type is cost reimbursement. The Government anticipates that the award will be made in September 2024.

In accordance with FAR 5.203, the solicitation is expected to be released at least fifteen (15) days after this posting and will be available electronically at beta.sam.gov. All information required for submission of a proposal will be contained in or accessible through the solicitation. The solicitation will also provide instructions for submission of any questions.

Responses to the solicitation will be due, at a minimum, forty-five (45) days from the release date.

All responsible sources may submit a proposal which will be considered by the agency. This notice does not commit the Government to award a contract. No collect calls will be accepted. No facsimile transmissions will be accepted.

For this solicitation, NIDA/NIMH requires proposals to be submitted online via the electronic Contract Proposal Submission (eCPS) website. For directions on using eCPS, go to the website https://ecps.nih.gov and then click on “How to Submit.”

This is NOT a Request for Proposals (RFP). Request for Proposals (RFP) No. 75N95024R00013 will be available electronically and may be accessed through the Contract Opportunities on sam.gov 15 or more calendar days after the issuance of this synopsis. THIS SOLICITATION WILL BE

AVAILABLE ELECTRONICALLY ONLY. OFFERORS ARE RESPONSIBLE FOR

ROUTINELY CHECKING THE WEBSITE FOR ANY POSSIBLE SOLICITATION

AMENDMENTS THAT MAY BE ISSUED. NO INDIVIDUAL NOTIFICATION OF ANY

AMENDMENTS WILL BE PROVIDED. All responsible sources may submit a proposal, which shall be considered by the agency.

Description