PAR-26-033-Full-Announcement.html

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PAR-26-033
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About this file

This document is a Notice of Funding Opportunity (NOFO) from the National Institute of General Medical Sciences (NIGMS) for the Institutional Biomedical Undergraduate Research Training (BURT) Program (T34). The funding opportunity aims to strengthen research training environments and develop undergraduate students who complete baccalaureate degrees in biomedical fields and transition into research-focused higher degree programs. Eligible organizations must enroll undergraduates and have received less than $50 million in NIH Research Project Grant funding annually over the past three fiscal years, with two application tracks available: Single Site and Community College Partnerships.

The grant provides support for full-time research training for 2-3 years, with trainees receiving stipends, tuition support, and training-related expenses. Applications are due on multiple dates between January 2025 and January 2028, with potential start dates ranging from February 2026 to December 2028. The program will fund up to 30 trainees per award, providing $12,500 per trainee annually for training-related expenses, and requires a summer research experience of at least 8 weeks. The funding instrument is a grant under the Biomedical Research and Research Training program (CFDA 93.859), administered by the Department of Health and Human Services National Institutes of Health, with a goal of developing a highly skilled biomedical research workforce.

PAR-26-033-Full-Announcement.html

Text of this file

Department of Health and Human Services

Part 1. Overview Information

Participating Organization(s)

National Institutes of Health (NIH)

Components of Participating Organizations

National Institute of General Medical Sciences (NIGMS)

Funding Opportunity Title

NIGMS Institutional Biomedical Undergraduate Research Training (BURT) Program (T34)

Activity Code

T34 Undergraduate NRSA Institutional Grants

Announcement Type

New

Related Notices

Check for any recent Notices of NIH Policy Changes that may impact application requirements.

Funding Opportunity Number (FON)

PAR-26-033

Companion Funding Opportunity

None

Number of Applications

See Section III. 3. Additional Information on Eligibility.

Assistance Listing Number(s)

93.859

Funding Opportunity Purpose

The goal of the Institutional Biomedical Undergraduate Research Training (BURT) program is to strengthen research training environments and develop a pool of well-trained students who:

Complete their baccalaureate degrees in biomedically-related fields, and
Transition into and complete biomedical, research-focused higher degree programs (such as Ph.D. or M.D./Ph.D.).

This notice of Funding Opportunity (NOFO) for a Limited Competition invites applications from eligible organizations to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the applications will be peer-reviewed, and only meritorious applications will be considered. This funding announcement provides support to eligible, domestic organizations to develop and implement effective, evidence-informed approaches to biomedical undergraduate training and mentoring to help build a strong biomedical research workforce for the nation.

Applicant organizations must enroll undergraduate students and have received NIH Research Project Grant (RPG) funding averaging less than $50 million in total costs (direct and F&A/indirect) per year over the last three fiscal years (FY). To promote undergraduate research training opportunities across a range of eligible organizations, the program will accept applications in two tracks:

Single Site: To support trainees from a single baccalaureate-degree granting organization.
Community College Partnerships: To support community college trainee development through strong collaborations between at least one associate-degree granting organization (that is, a community college) and at least one baccalaureate-degree granting organization.

The proposed research training programs will incorporate didactic, research, and career development elements to prepare trainees for careers that will have a significant impact on the health-related research needs of the nation.

This Notice of Funding Opportunity (NOFO) does not allow Trainees to lead an independent clinical trial, but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.

Funding Opportunity Goal(s)

To ensure the vitality and continued productivity of the research enterprise, NIGMS provides leadership in supporting the training of future scientists and developing research capacity throughout the country.

Key Dates

Posted Date

Open Date (Earliest Submission Date)

January 25, 2025

The following table includes NIH standard due dates marked with an asterisk.

Application Due Dates
Review and Award Cycles
New
Renewal / Resubmission / Revision (as allowed)
AIDS - New/Renewal/Resubmission/Revision, as allowed
Scientific Merit Review
Advisory Council Review
Earliest Start Date

February 25, 2026

February 25, 2026

Not Applicable

July 2026
October 2026

December 2026

May 25, 2026 *

May 25, 2026 *

Not Applicable

November 2026
January 2027

April 2027

September 25, 2026 *

September 25, 2026 *

Not Applicable

March 2027
May 2027

July 2027

January 25, 2027 *

January 25, 2027 *

Not Applicable

July 2027
October 2027

December 2027

May 25, 2027 *

May 25, 2027 *

Not Applicable

November 2027
January 2028

April 2028

September 25, 2027 *

September 25, 2027 *

Not Applicable

March 2028
May 2028

July 2028

January 25, 2028 *

January 25, 2028 *

Not Applicable

July 2028
October 2028

December 2028

May 25, 2028 *

May 25, 2028 *

Not Applicable

November 2028
January 2029

April 2029

September 25, 2028 *

September 25, 2028 *

Not Applicable

March 2029
May 2029

July 2029

All applications are due by 5:00 PM local time of applicant organization.

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

No late applications will be accepted for this Notice of Funding Opportunity (NOFO).

Expiration Date

September 26, 2028

Due Dates for E.O. 12372

Not Applicable

Required Application Instructions

It is critical that applicants follow the Training (T) Instructions in the How to Apply Application Guide, except where instructed to do otherwise (in this NOFO or in a Notice from the NIH Guide for Grants and Contracts). Conformance to all requirements (both in the How to Apply Application Guide, and the NOFO) is required and strictly enforced. Applicants must read and follow all application instructions in the How to Apply Application Guide, as well as any program-specific instructions noted in Section IV. When the program-specific instructions deviate from those in the How to Apply Application Guide, follow the program-specific instructions. Applications that do not comply with these instructions may be delayed or not accepted for review.

There are several options available to submit your application through Grants.gov to NIH and Department of Health and Human Services partners. You must use one of these submission options to access the application forms for this opportunity.
Use the NIH ASSIST system to prepare, submit and track your application online.
Use an institutional system-to-system (S2S) solution to prepare and submit your application to Grants.gov and eRA Commons to track your application. Check with your institutional officials regarding availability.
Use Grants.gov Workspace to prepare and submit your application and eRA Commons to track your application.

Table of Contents

Part 1. Overview Information Key Dates Part 2. Full Text of Announcement Section I. Funding Opportunity Description Section II. Award Information Other Award Budget Information Section III. Eligibility Information Section IV. Application and Submission Information Section V. Application Review Information Section VI. Award Administration Information Section VII. Agency Contacts Section VIII. Other Information

Part 2. Full Text of Announcement

Section I. Funding Opportunity Description

Purpose and Background Information The overall goal of the NIH Ruth L. Kirschstein National Research Service Award (NRSA) program is to help ensure that a pool of highly trained scientists is available in appropriate scientific disciplines to address the Nation's biomedical, behavioral, and clinical research needs. Each NIGMS-funded NRSA program is expected to provide a rigorous, well-designed research training program that includes mentored research experiences, courses, seminars, and additional training opportunities to equip trainees with the following skills required for careers in the biomedical research workforce:

Technical (for example, appropriate methods, technologies, and quantitative/computational approaches).
Operational (for example, independent knowledge acquisition, rigorous experimental design, interpretation of data, and conducting research in the safest manner possible).
Professional (for example, management, leadership, communication, and teamwork).

Developing a highly skilled biomedical research workforce is essential to strengthening the nation’s economic competitiveness and improving public health. Undergraduate education is key to pursuing a career in the biomedical research workforce, and over 45% of undergraduate students begin their education at associate-degree granting organizations (that is, community colleges). Structured research training programs that provide financial support, high quality mentoring, robust networks, authentic research experiences and opportunities for skills development lead to improved biomedical degree completion rates and enhanced commitment to a research career. Therefore, there is a strong need to develop research training programs to effectively support the skills and career development of undergraduate students.

Program Goal The goal of the Institutional Biomedical Undergraduate Research Training (BURT) program is to strengthen research training environments and develop a pool of well-trained students who:

Complete their baccalaureate degrees in biomedically-related fields, and
Transition into and complete biomedical, research-focused higher degree programs (such as Ph.D. or M.D./Ph.D.).

Program Considerations General Considerations: Applicants are strongly encouraged to contact program staff before preparing an application to verify that the proposed program is eligible and in alignment with NIGMS priorities. Funded programs are expected to be tailored to the organizational context(s) and have clearly defined training goals and objectives. Awards should foster safe and supportive research training environments that maximize success for all individuals in the program, demonstrate effective oversight of trainee development, and promote the use of evidence-informed undergraduate mentoring practices.

Programs should provide trainees with the following:

Foundational skills for rigorous biomedical research: Broad exposure to biomedical disciplines and strong foundations in scientific reasoning, rigorous research design, experimental methods, data analysis and interpretation.
Mentored research experiences: Well-designed, authentic research opportunities that enable trainees to conduct rigorous research safely, ethically, and with increasing self-direction. Authentic research experiences may take place through course-based research or in the context of a research group either at the applicant organization or at a partner organization with greater research activity. Training plans must include at least one trainee Summer Research Experience (SRE).
Scientific Collaboration and Communication: Cohort development activities that allow trainees to work effectively in teams with colleagues from various scientific disciplines and communicate scientific advances to a wide variety of audiences.
Career Development: The professional skills, knowledge, networks and experiences required to identify and transition into careers in the biomedical research workforce (the breadth of careers that sustain biomedical research in areas that are relevant to the NIH mission).

The BURT program will accept applications from eligible organizations in one of two tracks:

Single Site: To support trainees from a single baccalaureate-degree granting organization.
Community College Partnerships: To support community college trainee development through strong collaborations between at least one associate-degree granting organization (that is, a community college) and at least one baccalaureate-degree granting organization. To reinforce strong partnerships, NIGMS requires the participation of at least one Program Director/Principal Investigator (PD/PI) from each partner organization.

BURT awards are intended to provide research training opportunities to students from the breadth of biomedical disciplines at the organization. Narrowly focused programs will be a low priority for funding (such as those focused on a single biomedical discipline or approach at an organization with multiple relevant departments). Awards should prepare trainees to pursue advanced research training to address important biomedical problems in a range of fields from basic science to addressing the burden of chronic disease.

NIGMS encourages applications from a wide variety of eligible organizations, including those in Institutional Development Award (IDeA)-eligible states, Historically Black Colleges and Universities (HBCUs), Tribal Colleges and Universities (TCUs), and institutions that enroll significant proportions of Pell Grant-eligible students. Grantees are encouraged to recruit individuals who have the potential to significantly benefit from the program, including those who have not had substantial previous research experience and those whose financial circumstances would typically prevent them from pursuing biomedical research training. Consistent with existing NIGMS practices and applicable law, (1) funded programs may not use the race, ethnicity, or sex of a trainee or faculty candidate as an eligibility or selection criteria, and (2) NIGMS does not use the race, ethnicity, or sex of trainee candidates, trainees, or faculty in the application review process or funding decisions. Applicants and award recipients are encouraged to consult with their General Counsel to ensure all applicable laws and regulations are followed in program design and implementation.

Trainee Support: The training grant defrays the costs of stipends, tuition and fees, and training-related expenses, including health insurance, for the appointed trainees in accordance with the approved NIH NRSA support levels. Students are typically provided full-time support for the final 2–3 years of undergraduate studies to facilitate their preparation for and transition to research-focused biomedical higher degree programs (such as Ph.D. or M.D./Ph.D.). Training grant funds are not intended to support short-term undergraduate biomedical research training. New trainee cohorts are typically appointed in each year of the proposed program.

Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the applications will be peer-reviewed, and only meritorious applications will be considered.

This Notice of Funding Opportunity (NOFO) does not support of Trainees to lead an independent clinical trial, but does allow them to obtain research experience in a clinical trial led by a mentor or co-mentor.

See Section VIII. Other Information for award authorities and regulations.

Section II. Award Information

Funding Instrument

Grant: A financial assistance mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity.

Application Types Allowed

New

Resubmission

Revision

The OER Glossary and the How to Apply Application Guide, provide details on these application types. Only those application types listed here are allowed for this NOFO.

Clinical Trial?

Not Allowed: Only accepting applications that do not propose clinical trials.

Note: Appointed Trainees are permitted to obtain research experience in a clinical trial led by a mentor or co-mentor.

Need help determining whether you are doing a clinical trial?

Funds Available and Anticipated Number of Awards

The number of awards is contingent upon NIH appropriations and the number of meritorious applications.

Award Budget

Application budgets are not limited, but need to reflect the actual needs of the proposed project.

Recipients are expected to be familiar with and comply with applicable cost policies and the NRSA Guidelines (NIH Grants Policy Statement - Institutional Research Training Grants). Funds may be used only for those expenses that are directly related to and necessary for the research training and must be expended in conformance with OMB Cost Principles, the NIH Grants Policy Statement, and the NRSA regulations, policies, guidelines, and conditions set forth in this document.

Award Project Period

Awards may be for project periods up to five years in duration and are renewable.

Other Award Budget Information

Stipends, Tuition, and Fees

Kirschstein-NRSA awards provide stipends as a subsistence allowance to help defray living expenses during the research training experience.

NIH will contribute to the combined cost of tuition and fees at the rate in place at the time of award.

Stipend levels, as well as funding amounts for tuition and fees and the organizational allowance are announced annually in the NIH Guide for Grants and Contracts, and are also posted on the Ruth L. Kirschstein National Research Service Award (NRSA) webpage.

Trainee Travel

Travel for trainees to attend scientific meetings and workshops to support the research training experience is an allowable expense. NIGMS will provide up to $1,000 per trainee per year to travel (for programs supported at organizations outside the continental United States, $1,250 for travel per trainee per year will be provided). Plans for trainee travel should be well justified. Trainees must be appointed to the training grant at the time of the actual travel for this to be an allowable cost.

Summer Research Experience (SRE): Trainees are required to participate in at least one SRE, typically for at least 8 weeks, that will broaden and deepen their research training. SRE funds include per diem funds, and travel costs to and from the host organization. Funds for the SRE will be provided as follows:

$4,000 per trainee, to be used in accordance with the organizational policies as a per diem for a period of up to ten weeks.
An additional $750 for travel to and from the host organization (for programs supported at organizations outside the continental United States, $1,000 for travel per trainee per year will be provided).

NIGMS provides funds for the SRE for up to 50% of the awarded number of trainees at the time a competing award is made. For additional budget guidance on the SRE requirement, see Section VI.2 – Administrative and National Policy Requirements. SRE funds may not be used to support trainees at foreign organizations.

Training Related Expenses

NIGMS will provide funds to help defray other research training expenses, such as health insurance, staff salaries, consultant costs, equipment, research supplies, and faculty/staff travel directly related to the research training program. NIGMS will provide training related expenses (TRE) at a rate of $12,500/trainee/year. The maximum number of trainees supported on any BURT award is 30.

NIGMS expects organizations to prioritize the provision of trainee benefits, such as health insurance, using TRE funds. Remaining funds may be used for allowable costs associated with:

Salary support for key personnel.
Training activities - including skills development, cohort activities and seminar speakers.
Limited program evaluation costs.
Other program-related expenses may be included within the budget for training-related expenses.

TRE funds must be justified as specifically required by the proposed program and must not duplicate items generally available at the applicant organization.

Indirect Costs

Indirect Costs (also known as Facilities & Administrative [F&A] Costs) are reimbursed at 8% of modified total direct costs (exclusive of tuition and fees, consortium costs in excess of $50,000, and expenditures for equipment), rather than on the basis of a negotiated rate agreement.

NIH grants policies as described in the NIH Grants Policy Statement will apply to the applications submitted and awards made from this NOFO.

Section III. Eligibility Information

1. Eligible Applicants

Eligible Organizations

Higher Education Institutions - Includes all types
Public/State Controlled Institutions of Higher Education
Private Institutions of Higher Education

Nonprofits Other Than Institutions of Higher Education

Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)

Local Governments

Indian/Native American Tribal Governments (Federally Recognized)
Indian/Native American Tribal Governments (Other than Federally Recognized)
U.S. Territory or Possession

Other

Native American Tribal Organizations (other than Federally recognized tribal governments)
Faith-based or Community-based Organizations

Applicant organizations must (1) enroll undergraduates and (2) have received NIH Research Project Grant (RPG) funding averaging less than $50 million in total costs (direct and F&A/indirect) per year over the last three fiscal years (FY). RPG data are available through NIH RePORTER. For example, applications submitted in FY2026 will use data from FY 2023, FY 2024 and FY 2025.

All applications must include a baccalaureate degree-granting organization. The application must be submitted by the eligible organization with a unique entity identifier (UEI) and a unique NIH eRA Institutional Profile File (IPF) number. For organizations with multiple campuses (e.g., main, satellite, etc.), eligibility can be considered for an individual campus only if a UEI and a unique NIH eRA IPF number are established for the individual campus. For organizations that use one UEI or NIH IPF number for multiple campuses, eligibility is determined for the campuses together.

The sponsoring organization must assure eligibility and support for the proposed program. Appropriate information about eligibility and organizational commitment to the program should be detailed according to the Letters of Support attachment instructions in Section IV.

Foreign Organizations/International Collaborations

Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.

Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.

NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. This new requirement was effective, May 1, 2025.

Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

Required Registrations

Applicant Organizations

Applicant organizations must complete and maintain the following registrations as described in the How to Apply - Application Guide, to be eligible to apply for or receive an award. All registrations must be completed prior to the application being submitted. Registration can take 6 weeks or more, so applicants should begin the registration process as soon as possible. Failure to complete registrations in advance of a due date is not a valid reason for a late submission, please reference NIH Grants Policy Statement Section 2.3.9.2 Electronically Submitted Applications for additional information.

System for Award Management (SAM) – Applicants must complete and maintain an active registration, which requires renewal at least annually. The renewal process may require as much time as the initial registration. SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code.

NATO Commercial and Government Entity (NCAGE) Code – Foreign organizations must obtain an NCAGE code (in lieu of a CAGE code) in order to register in SAM.

Unique Entity Identifier (UEI)- A UEI is issued as part of the SAM.gov registration process. The same UEI must be used for all registrations, as well as on the grant application.

eRA Commons - Once the unique organization identifier is established, organizations can register with eRA Commons in tandem with completing their Grants.gov registration; all registrations must be in place by time of submission. eRA Commons requires organizations to identify at least one Signing Official (SO) and at least one Program Director/Principal Investigator (PD/PI) account in order to submit an application.

Grants.gov – Applicants must have an active SAM registration in order to complete the Grants.gov registration.

Program Directors/Principal Investigators (PD(s)/PI(s))

All PD(s)/PI(s) must have an eRA Commons account. PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons. If the PD/PI is also the organizational Signing Official, they must have two distinct eRA Commons accounts, one for each role. Obtaining an eRA Commons account can take up to 2 weeks.

Eligible Individuals (Program Director/Principal Investigator)

Any individual(s) with the skills and knowledge necessary to carry out the proposed research training program as the Training Program Director/Principal Investigator (Training PD/PI) is invited to work with their organization to develop an application for support.

BURT programs proposing Community College Partnerships require a PD/PI from each participating organization.

NIGMS encourages multiple PDs/PIs, particularly when each brings unique skill sets and experiences that will enhance training. At least one of the Training PDs/PIs must have a record of using rigorous biomedical research in a field applicable to the program. Additional PDs/PIs with relevant expertise may be included to strengthen the PD/PI team. Any PD/PI with a full-time appointment at the applicant organization may serve as the contact PD/PI. The PD(s)/PI(s) will be responsible for:
The overall direction, management, and administration of the program, including ensuring the training program is appropriately evaluated.
The selection, appointment and evaluation of trainees to the research training program.
The selection of faculty mentors for the program, assessment of mentor performance, and ensuring the program deals appropriately with substandard mentor performance.
Facilitating arrangements for trainees to participate in SREs by the spring of each year.
Monitoring and assessing the program and submitting all documents and reports as required.
When applicable, appointing members of the Advisory Committee and implementing their guidance as appropriate.

For organizations proposing multiple PDs/PIs, visit the Multiple Program Director/Principal Investigator Policy and submission details in the Senior/Key Person Profile (Expanded) Component of the SF424 (R&R) Application Guide.

2. Cost Sharing This NOFO does not require cost sharing as defined in the NIH Grants Policy Statement Section 1.2 Definition of Terms.

3. Additional Information on Eligibility

Number of Applications

NIGMS will accept only one application, and support only one award, per applicant organization.

NIH will not accept duplicate or highly overlapping applications under review at the same time per NIH Grants Policy Statement Section 2.3.7.4 Submission of Resubmission Application. This means that the NIH will not accept:

A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) or resubmission (A1) application.
A resubmission (A1) application that is submitted before issuance of the summary statement from the review of the previous new (A0) application.
An application that has substantial overlap with another application pending appeal of initial peer review (see NIH Grants Policy Statement 2.3.9.4 Similar, Essentially Identical, or Identical Applications)

Preceptors/Mentors

The selected faculty should demonstrate the ability to promote authentic research experiences for undergraduates (for example, through recent publications or abstracts at external scientific meetings with undergraduates). Research areas of the participating faculty must fall within the NIH mission. Programs should include faculty who are committed to undergraduate training, mentoring, and providing safe and supportive research environments. Programs are encouraged to recruit prospective preceptors/mentors from various career stages (for example, early-career as well as established faculty), and faculty from the breadth of biomedical disciplines at the applicant organization.

Trainees The PI/PD will select the trainees to be supported by the research training program. It is the responsibility of the applicant organization to establish the qualifications of the trainees, consistent with applicable law, before they are supported by the program.

The individual to be trained must be a citizen or a noncitizen national of the United States or have been lawfully admitted for permanent residence at the time of appointment. Additional details on citizenship, training period, and aggregate duration of support are available in the NIH Grants Policy Statement.

All trainees are required to pursue their research training full-time, normally defined as 40 hours per week, or as specified by the sponsoring organization in accordance with its own policies. Appointments are normally made in 12-month increments, and no trainee may be appointed for less than 9 months during the initial period of appointment, except with prior approval of NIGMS. NIGMS expects that, with satisfactory progress, trainees will complete the entire 2-3 year training experience. Training grant funds may not be used to support short-term undergraduate biomedical research training.

For Single Site programs: Trainees must be enrolled in a program leading to a baccalaureate degree in a biomedical field at the applicant organization.

For Community College Partnerships programs: At the time of initial appointment, trainees must be enrolled at the associate degree-granting organization with plans to complete a baccalaureate degree in a biomedical field. Upon transfer to a baccalaureate-degree granting partner organization, trainees funded through this program must be enrolled in a program leading to a baccalaureate degree in a biomedical field.

Section IV. Application and Submission Information

1. Requesting an Application Package The application forms package specific to this opportunity must be accessed through ASSIST, Grants.gov Workspace or an institutional system-to-system solution. Links to apply using ASSIST or Grants.gov Workspace are available in Part 1 of this NOFO. See your administrative office for instructions if you plan to use an institutional system-to-system solution.

2. Content and Form of Application Submission It is critical that applicants follow the Training (T) Instructions in the How to Apply - Application Guide except where instructed in this Notice of Funding Opportunity to do otherwise (in this NOFO, in a policy notice, or other notice from NIH Guide for Grants and Contracts). Conformance to the requirements in the How to Apply - Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions may be delayed or not accepted for review.

Page Limitations All page limitations described in the How to Apply - Application Guide and the Table of Page Limits must be followed.

Instructions for Application Submission The following section supplements the instructions found in the How to Apply - Application Guide and should be used for preparing an application to this NOFO.

SF424(R&R) Cover All instructions in the How to Apply - Application Guide must be followed.

Agency Routing Identifier Field: Applicants are expected to identify the track to which they are applying from the list below by entering the numerical code and abbreviation (for example, 1 SS) in the Agency Routing Identifier Field 4b of the application.
1 SS: Single Site Track
2 CCP: Community College Partnership Track

Descriptive Title of Applicant's Project: Use the format “Biomedical Undergraduate Research Training at [Name of Organization(s)]”

SF424(R&R) Project/Performance Site Locations

SF424 (R&R) Other Project Information

Project Summary/Abstract. Provide an abstract of the entire application. Include the goals, objectives, rationale and design of the research training program, as well as key activities in the training plan. Indicate the planned duration of appointments, the projected number of undergraduate trainees, and intended trainee outcomes.

Other Attachments:
Advisory Committee (1-page maximum). An Advisory Committee is not a required component of a training program. However, if an Advisory Committee is intended, provide a plan for the appointment of an Advisory Committee to monitor progress of the training program. The roles, responsibilities, and desired expertise of committee members, frequency of committee meetings, and other relevant information should be included. Describe how the Advisory Committee will assess the overall effectiveness of the program. Only pre-existing Advisory Committee members should be named in the application. Potential Advisory Committee members should not be identified or contacted prior to receiving an award. Please name the file “Advisory_Committee.pdf”.

The filename provided for each “Other Attachment” will be the name used for the bookmark in the electronic application in eRA Commons.

SF424(R&R) Senior/Key Person Profile Expanded Follow all instructions provided in the How to Apply - Application Guide.

Biographical Sketch: The personal statement should describe the individual's commitment to scientific rigor, training, and mentoring.

PHS 398 Cover Page Supplement

PHS 398 Training Subaward Budget Attachment(s)

Training Budget Follow all instructions provided in the SF424 (R&R) Application Guide with the following modifications:

Include all allowable categories of funds requested to support trainees in the program.
As per the instructions, request actual amounts for tuition/fees and provide justification. The amounts may be adjusted at the time of award.

Budget Justification: Follow all instructions provided in the SF424 (R&R) Application Guide with the following additions:

State the number of requested funded trainee slots per year. Provide a justification for the number of requested funded slots per year in the context of the following:Number of training grant eligible candidates.
Number of participating faculty.

Describe the total effort for key personnel in the budget justification (including effort charged to the grant and effort compensated by other sources).

PHS 398 Research Training Program Plan The PHS 398 Research Training Program Plan Form is comprised of the following sections:

Training Program Section
Faculty, Trainees, and Training Record Section
Other Training Program Section
Appendix - Note that the Appendix should only be used in circumstances covered in the NIH policy on appendix materials or if the NOFO specifically instructs applicants to do so.

Follow all instructions provided in the How to Apply - Application Guide.

Attention must be given to the required Training Data Tables for Undergraduate Programs. In the Program Plan, applicants should also summarize key data from the tables that highlight the characteristics of the training grant eligible pool, program faculty, organizational support, student outcomes, and other factors that contribute to the overall training environment of the program.

Training Program Program Plan Follow all instructions provided in the SF424 (R&R) Application Guide, with the following additional instructions:

Clearly describe how the program will further the goal of this NOFO to strengthen research training environments and develop a pool of well-trained students who complete their baccalaureate degrees, and transition into and complete biomedical, research-focused higher degree programs (such as Ph.D. or M.D./Ph.D.).
The application should emphasize how the program is tailored to the organizational context(s) and will enhance the development of safe and supportive research training environments that promote the success of all individuals (beyond simply providing financial assistance for trainees to conduct research).
Applications proposing Community College Partnership(s) should provide a sound rationale for selection of partnering institutions and include a clear description of how the proposed partnership(s) will enhance the research training environments at the participating organizations and facilitate an efficient and timely transfer for community college trainees (for example, articulation agreements).

Background

Describe the training program goals and objectives in the context of the “Training Outcomes” data requested below that provides data on previous student outcomes. Objectives should include degree completion rates, time-to-degree, and the rate of and time frame for graduates transitioning into and completing research-focused higher degree programs.
For Community College Partnership Track programs, describe current transfer rates and baccalaureate degree completion rates for students who have transferred between the participating organizations.

Program Plan

Program Administration: Include information on:Mechanisms for matching trainees with faculty mentors and overseeing the effectiveness of the trainee/research mentor match (including plans to address conflicts in the training environment that may impede trainee progress).
Succession plans for key administrative positions. In cases where a program administrator position is planned, describe the administrative capabilities that are essential to coordinate the program.
Program Faculty: Describe how the program faculty will:Provide research training opportunities for trainees in the breadth of biomedical research disciplines available at the organization.
Have adequate and sufficient time and resources to support authentic undergraduate research experiences. For undergraduate training programs, evidence of rigorous research can include publishable results, abstracts at external scientific meetings, or other measures of scientific accomplishment appropriate to the field(s).
Proposed Training:Describe how the curriculum and overall training plan use evidence-informed teaching and mentoring approaches to support undergraduate development.
Describe the mechanisms to ensure that trainees participate in authentic research experiences throughout the training period, including at least one SRE that broadens and deepens their research training (see Section VI. 2. for details of SRE policy). Community college partnership programs are expected to facilitate at least one SRE at a baccalaureate-degree granting partner for the trainee while enrolled at the community college.
Describe cohort activities to build scientific collaboration and communication skills. Include information on planned participation in scientific conferences, and support to facilitate trainee transition into the next phase of the biomedical research workforce pathway (e.g., applying to research-focused higher degree programs or funding opportunities).
Reminder: this NOFO does not support short-term training opportunities.
Training Program Evaluation: Reminder: While funded programs are expected to conduct ongoing program evaluations to monitor the effectiveness of the training activities, Training Program Evaluation is not a form of human subject research.
Trainee Candidates and Retention Plans: Describe the proposed financial support structure and appointment processes, including the stage in the trainees’ careers for which they will be supported on the training grant and the length of appointments.
Institutional Environment and Commitment to Training: Do not duplicate information provided in the Organizational Support and Eligibility Letter.
Training Outcomes:Describe baseline data for Recent Graduates (Table 8) on metrics relevant to the NOFO goals such as degree completion rates, time-to-degree, and the rate of and timeframe for graduates transitioning into and completing of research-focused higher degree programs. Include, as applicable, participation by Recent Graduates in authentic research experiences and scholarly activities to promote career development.
For Community College Partnership Track programs, as applicable, describe information on the outcomes of students involved in previous partnerships between the applicant and partner organizations.

Faculty, Trainees, and Training Record Participating Faculty Biosketches Participating faculty should provide a personal statement that describes the appropriateness of their research background for the proposed training program, their approach to teaching scientific rigor to undergraduate trainees, and their commitment to mentoring undergraduate students.

Letters of Support Organizational Eligibility and Support Letter (10-page maximum). The application must include a signed letter on letterhead from a President, Provost, Dean, or similar key leader that certifies (i) organizational eligibility, and (ii) describes the activities and resources provided by the organization to promote the success of the planned training program and its trainees. Applications lacking this letter will be considered incomplete and will be withdrawn prior to peer review. Please name the file “Organizational Eligibility and Support letter.pdf”.

The letter should describe:

(i) Organizational Eligibility: Certify that the applicant organization, as described by UEI and NIH IPF number:

Enrolls undergraduates.
Has received NIH Research Project Grant (RPG) funding averaging less than $50 million in total costs (direct and F&A/indirect) per year over the last three fiscal years (FY).
If the applicant organization is a community college, certify that at least one participating organization grants its own baccalaureate degrees.

(ii) Organizational Support: Describe the organizational commitment to the proposed training program. As applicable, this may include:

Supporting research training at the undergraduate level, fostering and rewarding excellence in training and mentoring, and providing trainees access to student support services.
Supporting the PDs/PIs, participating faculty and other key personnel (for example, salary support, protected time, start-up or bridge funding).
Supporting the scientific and educational facilities, technology, and curricular components in the proposed research training program (do not duplicate information provided in the Facilities and Other Resources attachment).
Developing and promoting a supportive research training environment and culture in which the highest standards of safety, scientific rigor, reproducibility, and responsible conduct are advanced.
Providing resources and expertise for evaluating the training outcomes of the program.
For community college partnership track programs, the letter should describe support to facilitate successful student transitions.

Other Letters of Support. Additional letters of support (for example, from partner organizations or organizations that will support SREs) are permitted; however, these letters may not contain any information required in the Organizational Support Letter described above.

Combine all Letters of Support into a single PDF file.

Data Tables The application must include the required Training Data Tables for undergraduate programs. Applications that do not contain the required tables, or that submit any additional tables in this attachment, will be considered noncompliant and will not be reviewed.

Other Training Program Section

Appendix:

Limited items are allowed in the Appendix. Follow all instructions for the Appendix as described in the How to Apply - Application Guide; any instructions provided here are in addition to the How to Apply - Application Guide instructions.

PHS Assignment Request Form

3. Unique Entity Identifier and System for Award Management (SAM) See Part 2. Section III.1 for information regarding the requirement for obtaining a unique entity identifier and for completing and maintaining active registrations in System for Award Management (SAM), NATO Commercial and Government Entity (NCAGE) Code (if applicable), eRA Commons, and Grants.gov

4. Submission Dates and Times Part I. contains information about Key Dates and times. Applicants are encouraged to submit applications before the due date to ensure they have time to make any application corrections that might be necessary for successful submission. When a submission date falls on a weekend or Federal holiday, the application deadline is automatically extended to the next business day.

Organizations must submit applications to Grants.gov (the online portal to find and apply for grants across all Federal agencies). Applicants must then complete the submission process by tracking the status of the application in the eRA Commons, NIH’s electronic system for grants administration. NIH and Grants.gov systems check the application against many of the application instructions upon submission. Errors must be corrected and a changed/corrected application must be submitted to Grants.gov on or before the application due date and time. If a Changed/Corrected application is submitted after the deadline, the application will be considered late. Applications that miss the due date and time are subjected to the NIH Policy on Late Application Submission.

Applicants are responsible for viewing their application before the due date in the eRA Commons to ensure accurate and successful submission.

Information on the submission process and a definition of on-time submission are provided in the How to Apply - Application Guide.

5. Intergovernmental Review (E.O. 12372) This initiative is not subject to intergovernmental review.

6. Funding Restrictions All NIH awards are subject to the terms and conditions, cost principles, and other considerations described in the NIH Grants Policy Statement. The National Research Service Award (NRSA) policies apply to this program. A NRSA appointment may not be held concurrently with another Federally sponsored fellowship, traineeship, or similar Federal award that provides a stipend or otherwise duplicates provisions of the NRSA.

Pre-award costs are allowable only as described in the NIH Grants Policy Statement Section 7.9.1 Selected Items of Cost. Note, however, that pre-award costs are not allowable charges for stipends or tuition/fees on institutional training grants because these costs may not be charged to the grant until a trainee has actually been appointed and the appropriate paperwork submitted to the NIH awarding component. Any additional costs associated with the decision to allow research elective credit for short-term research training are not allowable charges on an institutional training grant.

7. Other Submission Requirements and Information Applications must be submitted electronically following the instructions described in the How to Apply - Application Guide. Paper applications will not be accepted.

Applicants must complete all required registrations before the application due date. Section III. Eligibility Information contains information about registration.

For assistance with your electronic application or for more information on the electronic submission process, visit How to Apply – Application Guide. If you encounter a system issue beyond your control that threatens your ability to complete the submission process on-time, you must follow the Dealing with System Issues guidance. For assistance with application submission, contact the Application Submission Contacts in Section VII.

Important reminders:

All PD(s)/PI(s) must include their eRA Commons ID in the Credential field of the Senior/Key Person Profile form. Failure to register in the Commons and to include a valid PD/PI Commons ID in the credential field will prevent the successful submission of an electronic application to NIH.

The applicant organization must ensure that the unique entity identifier provided on the application is the same identifier used in the organization’s profile in the eRA Commons and for the System for Award Management. Additional information may be found in the How to Apply - Application Guide.

See more tips for avoiding common errors.

Mandatory Disclosure

Recipients or subrecipients must submit any information related to violations of federal criminal law involving fraud, bribery, or gratuity violations potentially affecting the federal award. See Mandatory Disclosures, 2 CFR 200.113 and NIH Grants Policy Statement Section 4.1.35.

Send written disclosures to the NIH Chief Grants Management Officer listed on the Notice of Award for the IC that funded the award and to the HHS Office of Inspector Grant Self Disclosure Program at grantdisclosures@oig.hhs.gov

Post Submission Materials Applicants are required to follow the instructions for post-submission materials, as described in the policy.

Section V. Application Review Information

1. Criteria

Only the review criteria described below will be considered in the review process.

Applications submitted to the NIH in support of the NIH mission are evaluated for scientific and technical merit through the NIH peer review system. While any information in the application relevant to the program goals can be included as part of the review process, the race, ethnicity, or sex of trainee candidates, trainees, or faculty may not be used as factors in the evaluation of applications.

For this particular announcement, note the following: NIGMS recognizes that rigorous, well-designed research training programs that further the goal of this NOFO can take place in various organizational environments and with mentors who have varying levels of NIH research project grant support. Reviewers will:
Evaluate proposed programs considering the program's track (single site or community college partnership), stated goals and objectives, organizational context, available resources, and the capacity of those resources to meet the stated goals and objectives.
Assess the strength of the program to support undergraduate trainees completing their baccalaureate degrees and undertaking appropriate next steps toward the goal of transitioning to and completing a research-focused higher degree program (such as Ph.D. or M.D./Ph.D.) to prepare them for careers in the biomedical research workforce.

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