PAR-25-383-Full-Announcement.html

The document is a Notice of Funding Opportunity (NOFO) for the Blueprint MedTech Translator program, a collaborative initiative by the NIH Blueprint for Neuroscience Research. The program aims to accelerate the development of cutting-edge medical devices for preventing, monitoring, diagnosing, and treating nervous system and neuromuscular disorders through a UG3/UH3 cooperative agreement mechanism. It will provide non-dilutive funding and additional support services to help innovators translate novel technologies from early-stage development towards clinical studies, with the goal of advancing patient access to groundbreaking medical devices.

The opportunity targets investigators with expertise in late-stage technology development, optimization, and first-in-human clinical studies, particularly those developing medical devices or with established collaborations with device manufacturers. While applications are not currently being solicited, potential applicants are encouraged to begin developing collaborative projects. The initiative falls under multiple federal grant programs, including Mental Health Research Grants (CFDA 93.853), Extramural Research Programs in Neurosciences and Neurological Disorders, and Discovery and Applied Research for Technological Innovations to Improve Human Health. The primary funding agency is the Department of Health and Human Services' National Institutes of Health, with the overarching mission of catalyzing technology translation and reducing the burden of nervous system disorders.