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This document is a Notice of Funding Opportunity (NOFO) for the Neuromodulation/Neurostimulation Device Development for Mental Health Applications (R21 Clinical Trial Not Allowed) federal grant opportunity.

The purpose of this NOFO is to encourage applications that will either develop novel brain stimulation devices or significantly enhance the effectiveness of currently FDA-approved or cleared brain stimulation devices for treating mental health disorders. The key focus areas are improving spatial resolution, depth of delivery, and precision of the devices. Multi-disciplinary teams with expertise in systems neuroscience, engineering, clinical, and regulatory affairs are encouraged to apply.

This grant opportunity is sponsored by the Department of Health and Human Services' National Institutes of Health under the Mental Health Research Grants program (CFDA 93.242). The anticipated funding mechanisms are grants, and eligible applicant types include non-profits, small businesses, state/local governments, and academic institutions. The application deadline and award details are not specified in this document.