PAR-25-188-Full-Announcement.html

This Notice of Funding Opportunity (NOFO) PAR-25-188 announces a UG3/UH3 phased cooperative agreement opportunity from the National Institute of Dental and Craniofacial Research (NIDCR) for behavioral and social intervention clinical trials research. The funding structure consists of a 2-year planning phase (UG3) followed by a potential 5-year implementation phase (UH3), with transition contingent upon meeting scientific milestones and feasibility requirements.

The opportunity is open to various applicant types including higher education institutions, nonprofits, small businesses, and tribal organizations. The UG3 phase supports scientific planning activities like small-scale data collection, feasibility assessment, and operational planning including protocol development and intervention manual creation. The UH3 phase funds intervention research from early mechanistic studies through implementation and cost-effectiveness research. This falls under the federal grant program 93.121 (Oral Diseases and Disorders Research) and is administered by the Department of Health and Human Services National Institutes of Health. The research must focus on behavior change interventions related to dental, oral, or craniofacial conditions.