PA-25-305-Full-Announcement.html

This is a Notice of Funding Opportunity (NOFO) announcement for the NIH Research Project Grant (Parent R01) that requires at least one clinical trial. This funding opportunity, identified as PA-25-305, is administered by the Department of Health and Human Services National Institutes of Health and supports discrete, specified research projects aligned with the interests of participating NIH Institutes and Centers. The grant is open to a wide range of applicants including state governments, higher education institutions, non-profits, small businesses, and tribal organizations.

The opportunity encompasses 24 different NIH research programs spanning diverse areas including lung diseases, cardiovascular health, mental health, diabetes, alcohol and drug use, environmental health, aging, vision research, and sleep disorders. Each program has its own CFDA number and specific research focus. The grant aims to support basic, clinical, social, and behavioral research across these disciplines, with emphasis on improving understanding of diseases, developing treatments, and advancing preventive measures. This is a civilian agency grant focused on biomedical research and requires the inclusion of at least one clinical trial in the proposed project.