PA-25-301-Full-Announcement.html

This is a Notice of Funding Opportunity (NOFO) announcement for the NIH Research Project Grant (Parent R01 Clinical Trial Not Allowed), solicitation number PA-25-301. The grant supports discrete, specified research projects aligned with the interests and missions of participating NIH Institutes and Centers, but explicitly excludes clinical trials. The Department of Health and Human Services National Institutes of Health is the funding agency.

The opportunity is open to a wide range of applicants including government entities, nonprofits, for-profit organizations, educational institutions, tribal organizations, and small businesses. It encompasses multiple funding activity categories including health, education, environment, food and nutrition, and income security/social services. The grant operates under 27 different federal grant programs covering diverse research areas such as cancer, lung diseases, cardiovascular health, mental health, diabetes, environmental health, aging, vision research, and numerous other biomedical fields, each with its own CFDA number and specific research objectives.