NOTICE OF INTENT to Sole Source.pdf

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Attached to
Renewal of StarDrop software and database Federal contract opportunity
Solicitation number
75N95025Q00230
Issued by
Department of Health and Human Services National Institutes of Health National Institute on Drug Abuse

About this file

This is a Notice of Intent to Sole Source for the renewal of StarDrop software and database. The National Center for Advancing Translational Sciences (NCATS) intends to award a sole source contract to Optibrium Limited under FAR Subpart 13.106-1(b) for a software license. The procurement is classified under NAICS code 513210 for Software Publishers with a size standard of 500 employees. The NCATS Chemical Genomics Center requires this software to quickly identify effective compounds in drug discovery, screening thousands of small molecules for research across various human disease targets.

The solicitation number is 75N95025Q00230, with responses due by August 8, 2025, at 10:00 am Eastern Time. While this is not a request for competitive proposals, interested parties may submit capability statements to Polina Klimenkova at polina.klimenkova@nih.gov. Respondents must provide details including unit price, list price, shipping costs, delivery period, payment terms, Unique Entity ID Number, Taxpayer Identification Number, and business size certification. All offerors must have an active registration in the System for Award Management (SAM).

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NOTICE OF INTENT TO SOLE SOURCE

1. NUMBER: 75N95025Q00230

2. TITLE: Renewal of StarDrop software and database

3. RESPONSE DATE: August 8, 2025, at 10:00 am Eastern Time.

4. PRIMARY POINT OF CONTACT:

Polina Klimenkova polina.klimenkova@nih.gov

5. DESCRIPTION:

The National Center for Advancing Translational Sciences (NCATS) intends to award a sole source contract under the authority of Federal Acquisition Regulation (FAR) Subpart 13.106-1 (b) Soliciting from a single source. For purchases not exceeding the simplified acquisition threshold, contracting officers may solicit from one source if the contracting officer determines that the circumstances of the contract action deem only one source reasonably available (e.g., urgency, exclusive licensing agreements, brand-name or industrial mobilization). This contract will be awarded to Optibrium Limited for the renewal of StarDrop sofware license.

NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE

The intended procurement is classified under NAICS code 513210 - Software Publishers with a Size Standard of 500 employees.

DESCRIPTION OF REQUIREMENT

The NCATS Chemical Genomics Center (NCGC) is tasked with identifying and developing novel small molecule leads against a wide spectrum of human disease targets, which it accomplishes by screening thousands of small molecules in collaboration with both intra-and extramural researchers. In pursuit of this goal, the Center has a strong internal transdisciplinary team of scientists who continually discover novel small molecules for application against a wide range of human diseases. As such, NCATS is in need of a license for software that allows to quickly identify effective compounds in drug discovery.

CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION

DETERMINATION

The determination by the Government to award a contract without providing for full and open competition is based upon the market research conducted. Specifically, Optibrium Limited is the only source that can provide the license for software.

In accordance with FAR part 10, the following market research was conducted to reach this determination. Specifically, contacts with knowledgeable individuals both in industry and Government, as well as reviews of available product literature, and review of recent market research undertaken to meet similar or identical requirements revealed no other sources. Therefore, Optibrium Limited is the only know source that meets the needs of this requirement.

mailto:polina.klimenkova@nih.gov

CLOSING STATEMENT

THIS SYNOPSIS IS NOT A REQUEST FOR COMPETITIVE PROPOSALS. However, interested parties may identify their interest and capability to respond to this notice.

A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. All responsible sources may submit a capability statement, proposal, or quotation which shall be considered by the agency. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement.

Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Unique Entity ID Number (UEI), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. FAR clauses 52.212-4, Contract Terms and Conditions – Commercial Items and 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders – Commercial Items apply to this acquisition.

All responses must be received by the closing date and time of this announcement and must reference the solicitation number, 75N95025Q00230 . Responses must be submitted electronically to Polina Klimenkova, Contract Specialist, at polina.klimenkova@nih.gov.

http://www.sam.gov/ mailto:polina.klimenkova@nih.gov

1. NUMBER: 75N95025Q00230
2. TITLE: Renewal of StarDrop software and database
3. RESPONSE DATE: August 8, 2025, at 10:00 am Eastern Time.
4. PRIMARY POINT OF CONTACT:
5. DESCRIPTION:
The National Center for Advancing Translational Sciences (NCATS) intends to award a sole source contract under the authority of Federal Acquisition Regulation (FAR) Subpart 13.106-1 (b) Soliciting from a single source. For purchases not exceeding the ...
NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE
DESCRIPTION OF REQUIREMENT
The NCATS Chemical Genomics Center (NCGC) is tasked with identifying and developing novel small molecule leads against a wide spectrum of human disease targets, which it accomplishes by screening thousands of small molecules in collaboration with both...
CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION DETERMINATION
CLOSING STATEMENT

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