NOTICE OF INTENT to Sole Source.pdf

PDF 113 KB Posted

Attached to
Mice vapor self-administration chambers Federal contract opportunity
Solicitation number
75N95025Q00212
Issued by
Department of Health and Human Services National Institutes of Health National Institute on Drug Abuse

About this file

This document is a Notice of Intent to Sole Source for alcohol inhalation chamber systems for mice and vapor generators for rats and mice. The National Institute on Drug Abuse (NIDA) intends to award a sole source contract to La Jolla Alcohol Research, Inc. for 16 additional vapor chambers, classified under NAICS code 334516 with a size standard of 1000 employees. The e-Vape system from LJARI is the only market solution allowing mice to self-administer vaporized drugs, and NIDA already has 32 of these chambers.

The research objectives include comparing sex and strain differences in mice drug self-administration, evaluating the role of neuropeptides and stress hormones in drug dependence, and studying the participation of these elements in specific brain regions. The solicitation number is 75N95025Q00212, with a response date of July 29, 2025, at 10:00 am Eastern Time. Interested parties may submit capability statements to Polina Klimenkova at polina.klimenkova@nih.gov, with the government retaining discretion on whether to proceed with a competitive or non-competitive procurement.

View the file

On GovTribe

Work with this file on GovTribe

  • Download the original file
  • Contacts named in this file
  • Similar government files
  • Ask GovTribe AI about this file

Text version

NOTICE OF INTENT TO SOLE SOURCE

1. NUMBER: 75N95025Q00212

2. TITLE: Alcohol inhalation chamber system for mice and vapor generators for rats and mice.

3. RESPONSE DATE: July 29, 2025, at 10:00 am Eastern Time.

4. PRIMARY POINT OF CONTACT:

Polina Klimenkova polina.klimenkova@nih.gov

5. DESCRIPTION:

The National Institute on Drug Abuse (NIDA) intends to award a sole source contract under the authority of Federal Acquisition Regulation (FAR) Subpart 13.106-1 (b) Soliciting from a single source. For purchases not exceeding the simplified acquisition threshold, contracting officers may solicit from one source if the contracting officer determines that the circumstances of the contract action deem only one source reasonably available (e.g., urgency, exclusive licensing agreements, brand-name or industrial mobilization). This contract will be awarded to La Jolla Alcohol Research, Inc.

to purchase additional alcohol inhalation chamber system for mice and vapor generators for rats and mice.

NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE

The intended procurement is classified under 334516 - Analytical Laboratory Instrument Manufacturing with a Size Standard of 1000 employees.

DESCRIPTION OF REQUIREMENT

NIDA - IRP/INRB – Neurobiology of Addiction Section requires vapor self-administration chambers for the study of brain circuits and areas participating in drug addiction, reward and aversion.

The e-Vape system of LJARI is the only in the market with the capability of allowing mouse to self-administer vaporized drugs. NIDA IRP already has 32 of these chambers.

The purpose is to acquire 16 additional vapor chambers for mice to study the neurobiology of drug addiction. The objectives are: 1. To compare sex and strain differences in mice regarding drug self-administration and the development of drug dependence; 2. To evaluate the participation of neuropeptides (small proteins that are active in the brain) and stress hormones on drug dependence; 3. To study the participation of neuropeptides and stress hormones in specific brain regions on drug dependence.

mailto:polina.klimenkova@nih.gov

CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION

DETERMINATION

The essential characteristics of the passive alcohol vapor system and vapor generators that limit the competition to a sole source is the ability to tightly control vapor delivery in quantity and time, compatibility with the systems that NIDA already has in the laboratory.

The material or service must be compatible in all aspects (form, fit, and function) with existing systems presently installed. The current equipment is a custom-made air-tight system equipped with levers and cue lights that are controlled by MedPC. Only La Jolla Alcohol Research products can meet this requirement.

In accordance with FAR part 10, the following market research was conducted to reach this determination. Specifically, contacts with knowledgeable individuals both in industry and Government, as well as reviews of available product literature, and review of recent (within the past 18-months) market research undertaken to meet similar or identical requirements revealed no other sources. Finally, a review of the GSA Advantage, and previous government acquisitions returned no results that meet the requirement.

Therefore, La Jolla Alcohol Research Inc. is the only know source that meets the needs of this requirement.

The intended source is:

La Jolla Alcohol Research Inc.

PO Box 13397 La Jolla, CA 92039 USA

CLOSING STATEMENT

THIS SYNOPSIS IS NOT A REQUEST FOR COMPETITIVE PROPOSALS. However, interested parties may identify their interest and capability to respond to this notice.

A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. All responsible sources may submit a capability statement, proposal, or quotation which shall be considered by the agency. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement.

Responses to this notice shall contain sufficient information to establish the interested parties' bona-fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Unique Entity ID Number (UEI), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. FAR clauses 52.212-4, Contract Terms and Conditions – Commercial Items and 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders – Commercial Items apply to this acquisition.

All responses must be received by the closing date and time of this announcement and must reference the solicitation number, 75N95025Q00212. Responses must be submitted electronically to Polina Klimenkova, Contract Specialist, at polina.klimenkova@nih.gov.

http://www.sam.gov/ mailto:polina.klimenkova@nih.gov

1. NUMBER: 75N95025Q00212
2. TITLE: Alcohol inhalation chamber system for mice and vapor generators for rats and mice.
3. RESPONSE DATE: July 29, 2025, at 10:00 am Eastern Time.
4. PRIMARY POINT OF CONTACT:
5. DESCRIPTION:
The National Institute on Drug Abuse (NIDA) intends to award a sole source contract under the authority of Federal Acquisition Regulation (FAR) Subpart 13.106-1 (b) Soliciting from a single source. For purchases not exceeding the simplified acquisitio...
NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE
DESCRIPTION OF REQUIREMENT
CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION DETERMINATION
PO Box 13397
La Jolla, CA 92039 USA
CLOSING STATEMENT

File details come from the government source that posted it. Updated .