Notice_of_Intent_NICHD-75N94024Q00185.pdf

INTRODUCTION

THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO

AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR

OPEN COMPETITION.

The National Institutes of Health, National Institute of Child Health and Development (NICHD), in support of the work of the National Institute of Diabetes, Digestive, and Kidney Disease (NIDDK), intends to award a purchase order without providing for full and open competition for Chromium GEM-X Single Cell Kits from 10x Genomics, Inc. 6230 Stoneridge Mall Road, Pleasanton, California, 94588-3260.

NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE

The intended procurement is classified under NAICS code 325414 with a Size Standard 1000.

REGULATORY AUTHORITY

The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Regulation (FAR) Circular (FAC) 2024-05 effective 05-22-2024.

This acquisition is conducted under the procedures as prescribed in FAR subpart 13-Simplified Acquisition Procedures at an amount not exceeding the simplified acquisition threshold ($250,000) and FAR Subpart 12- Acquisition of Commercial Items.

STATUTORY AUTHORITY

This acquisition is conducted under the authority of 41 U.S.C. 253(c) under provisions of the statutory authority of FAR Subpart 6.302- FAR 6.302-1—Only one responsible source and no other supplies or services will satisfy agency requirements 41 U.S.C. 253(c)(1).

Place of Performance National Institutes of Health National Institute of Diabetes, Digestive, and Kidney Disease (NIDDK) 9000 Rockville Pike Bethesda, MD 20892, United States

PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS

Description of the Requirement:

The National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) studies immune responses to viral infection. It has a requirement to profile the transcriptome of individual immune cells. For the analysis of the 16 bio samples it has a requirement to purchase a Chromium GEM-X Single Cell Kits from 10X Genomics to profile the gene expression in individual immune cells. These kits allow the partitioning individual cells from each bio sample into proprietary nanoliter-scale Gel Beads-in-emulsion (GEMs), where all cDNAs that are generated from the sample cell are labeled with the same bar code so that they can be attributed to the cell from which they derived. The kits also includes reagents for library generation.

CONTRACTING WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION

(INCLUDING BRAND-NAME) DETERMINATION

The determination by the Government to award a contract without providing for full and open competition is based upon previous the market research conducted as prescribed in FAR Part 10—Market Research. Only one source is available: Per FAR 13.106-1(b)(1) the Contracting Officer has determined a second component was added to the current study, on the same patients. It pertinent to use the same vendor for ensuring consistency and reproducibility of the study. Furthermore, it would be difficult to compare the results from the first part of the study with the second part without using the same vendor/products. Prior work done, allows this vendor access to unique proprietary information and using the same vendor helps to ensure the integrity of the study results. We must continue using this 10X Genomics in the project for scientific continuity.

CLOSING STATEMENT

This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice.

Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include:

unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Vendor/Contractor’s (UEI) the Unique Entity ID from SAM.gov is now the authoritative identifier for those doing business with the federal government.

The DUNS Number is no longer valid for federal award identification, the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.”

A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government.

The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement.

All responses to this notice shall be submitted electronically by 11:00 am Eastern Standard Time, on July 29, 2024 to Verne Griffin, verne.griffin@nih.gov and shall reference solicitation number NICHD- 75N94024Q00185.

mailto:verne.griffin@nih.gov