Notice_of_Intent_1.pdf

Notice of Intent to Sole Source

Solicitation Number: 75N94025Q00006 Solicitation Type: Sole Source (Non‐Competitive) Title: NIAAA: Service: GeoMx Maintenance Service Agreement NAICS / Size Standard: 811210 / 34 Million

Introduction

THIS IS A PRE‐SOLICITATION NON‐COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A PURCHASE ORDER WITHOUT PROVIDING FOR FULL AND OPEN COMPETITION. The National Institute of Child Health and Human Development (NICHD), Office of Acquisitions (OA), intends to negotiate and award a purchase order on a noncompetitive sole source basis to Bruker Spatial Biology to provide a GeoMx maintenance service agreement.

Background Information

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) purchased the GeoMx Digital Spatial Profiler (DSP) instrument to study tissue heterogeneity and the complexity of microenvironments in the spatial context related to alcohol‐induced organ injury and in various fibrosis models. GeoMx DSP is the only spatial biology platform that non‐destructively profiles the expression of RNA and protein from distinct tissue compartments and cell populations with an automated and scalable workflow that integrates with standard histology staining. This technique will help the lab discover novel biomarkers for disease severity, understand disease mechanism and progression, uncover drug mechanisms of action, and study preclinical models. Uninterrupted operations are critical for their research mission.

Currently, multiple labs and lab members at NIAAA use this instrument for their ongoing projects.

Purpose and Objectives

The purpose of this contract is to obtain a preventative maintenance and service agreement for the GeoMx DSP instrument.

Period of Performance

The period of performance is November 11, 2024 through November 10, 2025.

Contractor Requirements

The contractor needs to provide the following in their service maintenance agreement:

Gold GeoMx System Comprehensive Plan that encompasses the following:

Annual preventative maintenance and calibration

On‐site repairs

All spare parts and hardware

Service travel and labor

Software updates and upgrades (new feature sets)

Hot‐line response within 2 business days

On site response within 6 business days

Unlimited technical support; live phone and email support

Shipping costs

Live Technical Support available 5:00 AM – 5:00 PM PST

Applications specialist support

Sole Source Justification

Uninterrupted operations are critical for their research mission. Bruker Spatial Biology (BSB) is the sole manufacturer of BSB instrumentation and only engineers trained and certified by BSB are to repair and maintain BSB instruments. Any unauthorized use of third‐party products or third‐party instrument maintenance/repair services with BSB instruments shall void and nullify any warranty coverage on the instrument.

Regulatory Authority

This acquisition is conducted under the authority of the Federal Acquisition Regulations (FAR) Subpart 13.106‐1(b) Soliciting from a single source. (1) For purchases not exceeding the simplified acquisition threshold, contracting officers may solicit from one source if the contracting officer determines that the circumstances of the contract action deem only one source reasonably available (e.g., urgency, exclusive licensing agreements, or industrial mobilization).

FAR Clauses

The provision at FAR clause 52.212‐1, Instructions to Offerors – Commercial Items, applies to this acquisition.

The provision at FAR clause 52.212‐2, Evaluation – Commercial Items, is applicable. The Government will award a contract resulting from this notice to the offeror listed above. The following factors shall be used to evaluate the offer: The contractor shall demonstrate its ability to provide the detector listed that meets the specifications provided above.

FAR clause 52.212‐3, Offeror Representations and Certifications – Commercial Products and Commercial Services, is applicable. The Offeror shall complete only paragraph (b) of this provision if the Offeror has completed the annual representations and certification electronically in the System for Award Management (SAM) accessed through https://www.sam.gov. If the Offeror has not completed the annual representations and certifications electronically, the Offeror shall complete only paragraphs (c) through

(v) of this provision.

FAR clause at 52.212‐4, Contract Terms and Conditions – Commercial Products and Commercial Services applies to this acquisition.

FAR clause at 52.212‐5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders – Commercial Products and Commercial Services applies to this acquisition.

Additional Information

The North American Industry Classification System (NAICS) Code is 811210 and the Small Business Size Standard is 34 Million. This acquisition is being conducted under FAR Part 13, Simplified Acquisition Procedures, therefore the requirements of FAR Part 6, Competitive Requirements, are not applicable and the resultant award will include all applicable provisions and clauses in effect through the Federal Acquisition Circular 2024‐07 effective September 30, 2024.

This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties’ bona‐fide capabilities for fulfilling the requirement and include: unit price, list price, shipping and handling costs, the delivery period after contract award, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Unique Entity Identifier (UEI), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non‐competitive basis or to conduct a competitive procurement.

All responses must be received by October 31, 2024 5:00 PM ET and must reference solicitation number 75N94025Q00006. Responses shall be submitted electronically to nicole.freid@nih.gov. Responses will only be accepted if dated and signed by an authorized company representative. All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.