NMRProbes_Statement of Work.pdf

S

Statement of Work: NMR RF Probe Suite 1 Version 1.0 (2019) Double-click on for further assistance.

Use this document to detail the Statement of Work for services.

TITLE: NMR RF Probe Suite Requesting Lab/Division/Group: Physical Measurement Laboratory, 686.08

General Statement of Need The Magnetic Imaging Group is requesting a set of three NMR RF probes to improve its ability to provide measurements to the medical imaging community. These probes would provide improved capabilities including multinuclear capabilities as well as integration with external gradient coils to provide larger fields and better gradient linearity. At present existing NMR RF probes in the Magnetic Imaging Group cannot use external gradient fields and therefore limit the level of measurements that can be offered to customers.

Background Nuclear magnetic resonance spectroscopy and imaging require precise control of the radiofrequency (RF) pulses as well as their gradient waveforms to accurate measure biomarkers such as T1, T2, diffusion of materials. As the needs for the medical community continue to develop, there are needs beyond currently available equipment in the Magnetic Imaging Group.

Recent trends in the medical imaging community as well as developments at NIST require NMR RF probes capable of experiments that range from 0.065 T to 9.4T in magnetic field strength, multinuclear decoupling and detection, and augementation of gradient waveforms to better serve the needs of our customers. To this end, the Magnetic Imaging Group would like to acquire new NMR RF probes capable of providing these measurements. This project would provide new magnetic field measurements to customers as well as provide a platform to improve sample handling and measurement. These additions would bring improved measurement capabilities to the Magnetic Imaging Group and provide provide flexibility for future work.

Objective(s) This project is designed to add three new NMR RF probes to the existing set of NMR probes owned by the Magnetic Imaging Group. Thse probes allow for additional flexibility unavailable in the existing probes such as non-proton isotopes and compatibility with external gradient systems. These new capabilities will enchance the work of our group to the NIST mission of providing quantitative and precise measurements for medical imaging.

Scope/General Requirements In acquiring a suite for NMR RF probes, the Magnetic Imaging Group will enhance the capabilities of services provided to the medical imaging community. These probes will improve the measurements by reducing uncertainty in diffusion measurements, allow for additional isotopes and field strengths to be measured, and allow for development of new sample methods

Statement of Work: NMR RF Probe Suite 2 minimizing sample handling and stress during measurements.

Tasks/Specific Requirements

Task Number or Reference

Description Format Quantity Due Date

1 Design, Develop, and Produce three NMR RF probes for various magnetic field strengths and sample systems as desiginated previously

Hardware 1 4 months

ARO

Performance Requirement Summary (for Performance Work Statement)

Desired Output Required Service Performance Standard

Monitoring Method

3 NMR RF Probes that meet previously designated specifications

Design and construction of 3 NMR probes for various field strengths and targeted sample spaces

Upon delivery to NIST, experiments will assess behavior of all NMR probes to ensure they match system specifications and produce data to match similarly available probes.

N/A

Task 1 - Title NMR RF Probe Suite

Task 2 - Title [Enter details here.]

Task 3 - Title [Enter details here.]

Statement of Work: NMR RF Probe Suite 3

Delivery Deliverable Schedule

Deliverable Description Quantity/Media Date Required

RF Probe

3T 1H/X/Lock NMR RF probe with VT, reduced 13C background, 1H linewidth of 0.7 Hz, accepting 5mm NMR tubes

1 4 months ARO

RF Probe

0.55T 1H/X/Lock NMR RF probe with VT, reduced 13C background, 1H linewidth of 1 Hz, accepting 5mm NMR tubes

1 4 months ARO

RF Probe

3T microimaging NMR RF probe, accepting 20mm sample apparatus, quadrature RF design, high RF homogeneity of 2% of central 12mm

1 4 months ARO

[Enter details here.]

Government-Furnished Property, Material, Equipment, or Information (GFP, GFM, GFE, or GFI) Gradient/Shim insert in development for system will have a base to center of field distance of approximately 408mm. RF probes will need to have sufficient length to mount to the bottom of the gradient/shim insert and reach the center of field of the gradient stack (co-located with the center of field for the NMR magnet)

Security N/A

Travel N/A

Special Material Requirements N/A

Other Unique Requirements N/A

Statement of Work: NMR RF Probe Suite 4

Place of Performance NIST – Boulder

Period of Performance 7 business days from delivery to NIST - Boulder

Provide suggestions to improve this form by clicking here.

https://oaam.nist.gov/OAAMAcquisitions/FormFeedback/default.aspx