NIEHS2015020_-_NextGen_Solicitation_-_Mod_001_-3-2015.pdf

NIH/National Institute of Environmental Health Sciences (NIEHS)

Solicitation No: NIEHS2015020 - Mod # 001 Date Issued: March 5, 2015

Due Date: TUESDAY, MARCH 17, 2015 by 1:00 pm et

Issued by: Deitra C. Lunney, Contract Specialist Email: lunney@niehs.nih.gov Telephone: 919-541-0387

Courier/Overnight Delivery USPS Mail Delivery NIH/NIEHS/Office of Acquisitions NIH/NIEHS Attn: Deitra Lunney Attn: Deitra Lunney Keystone Office Bldg., Rm. 1045 Office of Acquisitions 530 Davis Drive P.O. Box 12874, MD K1-04 Morrisville, NC 27560 Research Triangle Park, NC 27709

Goods/Services to be purchased: NextGen Sequencing Project

The NIEHS intends to acquire NextGen Sequencing Services to commence on April 1, 2015 through March 31, 2020 for an ordering period of five (5) years.

Award will be a firm-fixed price Indefinite-Delivery – Requirements contract.

NOTICES:

1. Modification #001 is issued to provide clarification and additional information to CLIN line items. The modification also deletes CLIN 6.

2. This is a Combined Synopsis/Solicitation.

3. Solicitation is issued as Full and Open Competition.

The NAICS Code is 541380 with a Size Standard of $14.0 Million.

4. Any questions regarding this announcement must be submitted in writing no later than Friday, March 6, 2015, 3:00 pm edt to Deitra Lunney via email at lunney@niehs.nih.gov.

mailto:lunney@niehs.nih.gov

I. Combined Synopsis Solicitation.

This is a combined synopsis/solicitation for commercial services prepared in accordance with the format in Subpart 12.6, as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. This solicitation is issued as a Request for Quotations (RFQ) under NIEHS2015020. This solicitation document incorporates all mandatory commercial item provisions and clauses that are in effect through Federal Acquisition Circular (FAC) 2005-78 dated December 26, 2014.

FULL AND OPEN COMPETITION - NAICS Code/Size: 541380/$14.0 Million

II. Instructions:

For any questions regarding this announcement or requests for additional information must be submitted in writing to Deitra Lunney via email at lunney@niehs.nih.gov. Notification of any changes shall be made only via the FedBizOpps solicitation posting site. Quotations submitted in response to this notice shall include the solicitation number, DUNS and Tax ID/Employer Identification Numbers, payment terms, and be signed, dated and submitted to an address shown on page 1 of this RFQ. Vendors not registered in the Central Contractor Registration (CCR) database at the time the requirement is to be awarded will not be considered. Vendors may register with CCR by calling 1-888-227-2423 or (269) 961-5757, or by accessing www.ccr.gov.

FAR 52.212-3, Offeror Representations and Certifications-Commercial Items (Dec 2014) is included by reference (full text is available electronically at http://www.acquisition.gov/far. A completed copy of this provision must be included with response. Offeror shall complete only paragraph (j) of this provision if the offeror has completed the annual representations and certifications electronically at http://orca.bpn.gov. If an offeror has not completed the annual representations and certifications electronically at the ORCA website, the offeror shall complete only paragraphs (b) through (i) of this provision.

III. Basis for Award:

Offeror should be aware that the Government shall perform a “best value analysis” and the selection for award shall be made to the Offeror whose proposal is most advantageous to the Government, taking into consideration the technical factors listed in the solicitation and the total proposed price across the contract ordering period.

http://www.acquisition.gov/far

IV. Supplies, Services, and Prices

This will be awarded as an Indefinite-Delivery Requirements Contract. Prices quoted will be binding on the contract for the estimated ordering periods as listed below. Task orders will be placed on an as-needed basis with the totals for each item not exceeded the quantity listed.

Furnish and deliver, as required by the National Institute of Environmental Health Sciences, at the following fixed price(s):

Provide NextGen Sequencing Services as per the Statement of Work (pages 7 - 11).

Unit Extended

Items Quantity Unit Price Price

CLIN 1: Description of Services – Est. Ordering Period – 4/01/2015-3/31/2016

Illumina HiSeq DNA Sequencing Samples:

Lane of RNA-Seq or DNA-Seq 50 ea ___________ ____________ (Generally, 4 samples are multiplexed per lane to include 4 RNA or DNA extractions, 4 library constructions and sequencing reagents for 100bp paired end sequencing for one lane.)

The average project would involve 4 lanes.

Sequence Data Analysis:

Analysis per lane, RNA-Seq or DNA-Seq 50 ea ___________ ____________

Unit of Transcript Confirmation Sequencing 8 ea ___________ ____________

Metabolomic Samples 60 ea ___________ ____________ (Average # samples/project=30)

Proteomic Samples 40 ea ____________ ____________ (Average # samples/project=20)

TOTAL CLIN 1: $ _______________________

CLIN 2: Description of Services – Est. Ordering Period – 4/01/2016-3/31/2017

(Generally, 4 samples are multiplexed per lane to include 4 RNA or DNA extractions, 4 library constructions and sequencing reagents for 100bp paired end sequencing for one lane.)

The average project would involve 4 lanes.

(Average # samples/project=30)

TOTAL CLIN 2: $ _______________________

CLIN 3: Description of Services – Est. Ordering Period – 4/01/2017-3/31/2018

(Generally, 4 samples are multiplexed per lane to include 4 RNA or DNA extractions, 4 library constructions and sequencing reagents for

(Average # samples/project=30)

TOTAL CLIN 3: $ _______________________

CLIN 4: Description of Services – Est. Ordering Period – 4/01/2018-3/31/2019

(Generally, 4 samples are multiplexed per lane to include 4 RNA or DNA extractions, 4 library constructions and sequencing reagents for

(Average # samples/project=30)

TOTAL CLIN 4: $ _______________________

CLIN 5: Description of Services – Est. Ordering Period – 4/01/2019-3/31/2020

(Generally, 4 samples are multiplexed per lane to include 4 RNA or DNA extractions, 4 library constructions and sequencing reagents for

Unit of Transcript Confirmation Sequencing 8 ea ___________ ____________

Metabolomic Samples 60 ea ___________ ____________ (Average # samples/project=30)

TOTAL CLIN 5: $ _______________________

Total CLIN 1: $ _________________

Total CLIN 2: $ _________________

Total CLIN 3: $ _________________

Total CLIN 4: $ _________________

Total CLIN 5: $ _________________

TOTAL ALL CLINS: $ _______________________