Questions and Responses v.1.pdf

This Request for Information from the National Institutes of Health seeks information from potential DNA sequencing service providers to support the BRAIN Initiative Cell Atlas Network. Interested organizations are invited to describe their capabilities and experience in areas such as high-throughput sequencing operations, data management protocols, sequencing costs and turnaround times. Responses should include details on sequencing pipelines, library types processed, data delivery options, quality assurance procedures, pricing structures and sequencing volumes achieved. Feedback is also requested on potential challenges in using centralized sequencing facilities and recommendations for mitigating issues. Responses of up to ten pages are due by July 2, 2021 to help inform project planning for this large-scale effort to map cell types and genetic variations in the human, non-human primate and mouse brains through RNA, epigenomic and other sequencing analyses.