SOW LSRFortessa X-20 SORP.doc

STATEMENT OF WORK

1) BACKGROUND INFORMATION

The Lymphocyte Activation Section (LAS) of the Laboratory of Immunogenetics (LIG) investigates mechanisms involved in cell signaling. The mission focuses on the cellular and molecular mechanisms that underlie the signaling functions of immune cell receptors. This work encompasses a wide spectrum of experimental approaches from structural determination of immune receptors to live-cell image analysis of the behavior of chemotactic receptors. The molecular mechanisms underlying the activation of B lymphocytes to proliferate and differentiate into clones of antibody producing cells. The B cell activation, which is triggered by the binding of foreign antigens to the B cell antigen receptor, initiates a signaling cascade that leads to the transcription of a variety of genes associated with B cell activation. This targets antigens into the cell for processing and presentation to helper T cells uses the tools of biology, biochemistry, and molecular biology to dissect these functions and to understand their regulation. Knowledge gained from these studies to develop new strategies for enhancing antibody responses in the design of vaccines and to deactivate antibody responses in autoimmune disease. This acquisition directly addresses this mission by providing flow cytometer operation at peak performance.

2) PURPOSE AND OBJECTIVES OF THE ACQUISITION

The scope of this acquisition is to provide a service agreement for a LSRFortessa X-20 SORP, High Throughput Sampler, and FACS Flow Supply System, which includes five (5) lasers. These instruments are constantly in use daily and if it were put out of action due to lack of maintenance or mechanical failure then ability of the investigators in the LIG to conduct their research would be severely handicapped. It is for this reason that a Service Agreement is essential.

3) CONTRACTOR REQUIREMENTS:

a) the Contractor shall provide service coverage for Becton Dickinson LSRFortessa X-20 SORP – serial #R656385165 that includes the following:

· Parts, labor and travel for remedial repair,

· 2 Preventative Maintenance Inspections to be performed during twelve-month period of performance,

· 2 PM Kits,

· Software Revisions released during the period of performance,

· Unlimited service visits, Monday-Friday,

· Unlimited telephone support for instruments, reagents, and applications, and

· Response within 48-hours to a request for emergency on-site service Monday-Friday.

b) the Contractor shall provide service coverage for the High Throughput Sampler – serial #U64770161190 that includes the following:

· Depot Level Repair between the manufacturer, and customer,

· 1 Preventative Maintenance Inspection to be performed during the twelve-month period of performance,

· 1 PM Kit,

· An emergency replacement will be provided within two (2) working days,

· Unlimited telephone support for instruments, reagents and applications, and

· Labor, shipping and parts, excluding consumables items.

c) the Contractor shall provide service coverage for the FACS Flow Supply System – serial #N3492775086 that includes the following:

· Parts, labor and travel for remedial repair,

· Unlimited service visits, Monday-Friday, and

· Unlimited telephone support for instruments, reagents and applications.

4) CONTRACTOR SUPPLIED MATERIALS

The Contractor shall provide all necessary parts and equipment necessary to perform remedial repair and planned maintenance of the above equipment.

5) GOVERNMENT FURNISHED MATERIALS

No Government furnished materials are provided under this contract.

6) REPORTING REQUIREMENTS AND DELIVERABLES

The Contractor shall provide annual preventative maintenance reports and service repair reports.

7) PERIOD OF PERFORMANCE

The period of performance is December 1, 2019 – November 30, 2020.

8) INSPECTION AND ACCEPTANCE

a) All work will be inspected and approve by a LIG representative at the completion of any repairs and at the completion of the annual maintenance.

b) All work will be completed in accordance with industry standards.