Solicitation__NIAID-NOI-15-1729138_(SOW).doc

STATEMENT OF WORK

Solicitation# NIAID-NOI-15-1729138

LEASE FOR RESEARCH BIOSPECIMEN STORAGE

IHSS, LIR, NIAID

1) BACKGROUND INFORMATION

The major theme of the Laboratory of Immunoregulation (LIR) continues to be the elucidation of cellular and molecular mechanisms of the regulation of the human immune response in health and disease. A major component of this effort is focused on the study of the immunopathogenic mechanisms of HIV disease. The International HIV/STD Section (IHSS) of the LIR is led by Tom Quinn, M.D., a tenured investigator at the Johns Hopkins School of Medicine in Baltimore, Maryland. The functional priorities of the IHSS are to 1) define the unique epidemiologic, clinical, virologic, and immunologic features of HIV infection in developing countries; 2) examine the viral kinetics and other biological and behavioral factors associated with HIV transmission; 3) characterize the molecular strains of HIV by region for infectiousness, transmission, and immunologic response; 4) develop and evaluate novel interventions to prevent HIV transmission, including microbicides, circumcision and vaccines; 5) examine the efficacy of antiretroviral drugs in preventing transmission and increasing survival in developing countries; 6) define the epidemiology, risk factors, and transmission of C. trachomatis genital tract infections in individuals internationally; 7) define the immunopathogenesis of C. trachomatis infection in pelvic inflammatory disease, infertility and blinding trachoma and; 8) implement clinical trials aimed at facilitation of more effective control of blinding trachoma in Africa.

A. Description:

A major component of the IHSS research program is the maintenance of a freezer repository for storage and access to clinical research samples.

B. Scope of this RFP:

The purpose of this SOW is to extend the refrigerated warehousing and storage services at 855 N. Wolfe Street to accommodate freezers belonging to the Laboratory of Immunoregulation, NIAID, NIH.

The NIAID Laboratory of Immunoregulation is renting space from Forest City-New East Baltimore Partnership to house freezers storing precious research samples. The rented space accommodates room for at least 16 freezers/liquid nitrogen storage for Dr. Tom Quinn, Section Chief, International HIV/STD Section, LIR, NIAID. Renting this space at Johns Hopkins facilitates Dr. Quinn’s access to his samples and expedites research in his lab and will collaborators at Johns Hopkins and NIH.

C. Specifications

Maintenance of Common Area, HVAC expenses, electrical and rental fees apply

Common Area Maintenance, per RSF

HVAC Expense, per RSF

Electrical, per RSF

Triple-net base rent, per RSF

Two Parking Passes, per month each

Performance period:

Base plus 4 Option Years

3) VENDOR REQUIREMENTS:

Landlord (Forest City-New Baltimore) shall provide normal utility power only for operation of Tenant’s equipment and shall not provide any back-up power systems. In no event shall Landlord be liable to Tenant for any compensation or reduction of rent for the unavailability of any utility service provided by Landlord to the extent that such unavailability is caused by an event or event(s) outside of Landlord’s reasonable control; provided, Landlord shall use reasonable efforts to restore such services or utility systems’ operation. Tenant acknowledges that Landlord shall provide no additional services for the Premises. Landlord shall be permitted to enter the Premises upon 24 hours prior notice, except in the case of an emergency, to monitor Tenant’s compliance with the requirements of this agreement.

4) GOVERNMENT REQUIREMENTS

a) Tenant shall pay an annual installment of the Annual Rent in effect in advance on or before each anniversary of the Commencement Date. If Tenant fails to pay the Annual Rent when due, Landlord shall provide written notice to Tenant indicating the default, and if Tenant does not pay the Annual Rent as due within thirty days of the notice, Landlord may terminate the Lease. Late payment of Annual Rent shall bear interest from the date due until paid at the highest rate allowed by law.

b) Tenant shall not make any additions or alterations to the Premises without Landlord’s prior written approval.

c) Tenant shall keep the Premises and every part thereof in good order, condition and repair. Tenant shall be responsible for maintaining all of Tenant’s equipment in good order, condition and repair.

d) Any and all hazardous materials necessary for Tenant’s use of the Premises shall be used, generated, stored and disposed of in compliance with all applicable law and regulations. At the expiration of the Term, Tenant shall promptly remove or remediate all hazardous materials from the Premises in a manner consistent with accepted “best practices” and in compliance with all legal requirements.

e) Tenant shall be permitted to use the Premises solely for the storage of Tenant’s property in freezers located within the Premises. Tenant shall at all times comply with all applicable laws and regulations regarding its use of the Premises. Additionally, Tenant shall comply with the Building standard rules and regulations promulgated by Landlord.

f) Tenant cannot assign or sublease its rights under this Agreement.

g) Tenant shall indemnify, defend and save harmless Landlord from all claims, loss or damage resulting from (i) Tenant’s breach of these terms, (ii) the negligence or misconduct of Tenant or Tenant’s contractors, licensees, agents or employees, or (iii) any damage caused to any person or property in the Building during the Term as a result of Tenant’s use of the Premises. Tenant shall have appropriate insurance or be self-insured in a manner reasonably satisfactory to Landlord. Self-insurance provided by state and federal governments is acceptable. This insurance must cover all risks, damage and liability relating to Tenant’s use of the Premises and Tenant’s equipment and or property located at the Premises.

h) If the Building or the Premises are damaged by a casualty, either Tenant or Landlord may terminate this agreement. Tenant shall be responsible for insuring its equipment and property located within the Premises and Landlord shall have no liability to Tenant for the same.

i) Upon the end of the Term, Tenant shall vacate the Premises in the same condition except for normal wear and tear and remove all of its personal property, leaving the Premises in broom clean condition.

Government furnished materials are provided under this procurement: at least 16 freezers/liquid nitrogen

5) REPORTING REQUIREMENTS AND DELIVERABLES

Prior Procurement History and Justification The LIR-International HIV/STD Section is obtaining Freezer Support Services to house a bio-storage repository of rare clinical samples critical to the scientific program of the LIR and NIAID. These samples are cyropreserved archival samples from clinical trials conducted in the LIR in collaboration with national and international clinical research centers. This service will be renewable on a Base Year plus 4 Option Years