Amendment 002 NHLBI-CSB-(AR)-2012-018B-CRS.PDF

AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT

11. CONTRACT 10 CODE rA~E

OF PAGES

I 4

2. AMENDMENT/MODIFICATION NO. 3. EFFECTIVE DATE 4. REQUISITION/PURCHASE REa, NO.

15. PROJECT NO. (If applicable)A002 OS/23/2012

6. ISSUED BY CODE 7. ADMINISTERED BY (If other than Item 6) CODE

I

NIH - NHLBI NIH - NHLBI

6701 Rockledge Drive, Rockledge 2, Room 6135 6701 Rockledge Drive, Rockledge 2, Room 6135 Bethesda, MD 20892 Bethesda, MD 20892 Altn: Robin Jeffries, Contracting Specialist Altn: Robin Jeffries, Contracting Specialist

8. NAME AND ADDRESS OF CONTRACTOR (No" street, county, State and zip Code) ~ 9A. AMENDMENT OF SOLICITATION

NO.

D NHLBI-CSB-(AR)-2012-018B-CRS

98. DATED (SEE ITEM 11)

04/26/2012

10A. MODIFICATION OF CONTRACT/ORDER NO.

D 108. DATED (SEE ITEM 13)

CODE I FACILITY CODE

11. THIS ITEM ONLY APPLIES TO AMENDMENTS OF SOLICITATIONS

(8 The above numbered solicitation is amended as set forth in Item 14. The hour and date specified for receipt of Offers D is extended, (8 is not extended.

Offers must acknowledge receipt of this amendment prior to Ihe hour and dale specified in the solicitation or as amended, by one of the following methods:

(a) By completing items 8 and 15, and returning 1 copies of the amendment; (b) By acknowledging receipt of this amendment on each copy of the offer submitted;

or (c) By separate leiter or telegram which includes a reference to the solicitation and amendment numbers. FAILURE OF YOUR ACKNOWLEDGMENT TO BE RECEIVED AT THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERS PRIOR TO THE HOUR AND DATE SPECIFIED MAY RESULT IN REJECTION OF YOUR OFFER. If by virtue of this amendment your desire to change an offer already submitted, such change may be made by telegram or letter, provided each telegram or leller makes reference 10 the solicitation and this amendment, and is received prior to the opening hour and dale specified.

12. ACCOUNTING AND APPROPRIATION DATA (if required)

13. THIS ITEM ONLY APPLIES TO MODIFICATION OF CONTRACTS/ORDERS.

IT MODIFIES THE CONTRACT/ORDER NO. AS DESCRIBED IN ITEM 14.

CHECK ONE A. THIS CHANGE ORDER IS ISSUED PURSUANT TO: (Specify authority) THE CHANGES SET FORTH IN ITEM 14 ARE MADE IN THE CONTRACT ORDER NO.

IN ITEM 10A.

D D D D

B. THE ABOVE NUMBERED CONTRACT/ORDER IS MODIFIED TO REFLECT THE ADMINISTRATIVE CHANGES (such as changes in paying offce, appropriation date, etc.) SET FORTH IN ITEM 14, PURSUANT TO THE AUTHORITY OF FAR 43.103(b).

C. THIS SUPPLEMENTAL AGREEMENT IS ENTERED INTO PURSUANT TO AUTHORITY OF:

D. OTHER (Specify type of modification and authority)

E. IMPORTANT: Contractor D is not, D is required to sign this document and return copies to the issuing offce.

14. DESCRIPTION OF AMENDMENT/MODIFICATION (Organized by UCF section headings, inciuding solicifation/contract subject matter where feasible.)

Refer to the following pages for Amendment #A002 details.

Except as provided herein, all terms and conditions of the document referenced in Item 9A or 10A, as heretofore changed, remains unchanged and in full force and effect.

15A. NAME AND TITLE OF SIGNER (Type or print) 16A. NAME AND TITLE OF CONTRACTING OFFICER (Type or print)

158. CONTRACTOR/OFFEROR 15C. DATE SIGNED 16B. UNITED STATES OF AMERICA 16C. DATE SIGNED

(Signature of person authorized to sign) (Signature of Contracting Offcer)

NSN 7540-01-152-8070

Previous edition unusable

STANDARD FORM 30 (REV. 10.83)

Prescribed by GSA FAR (48 CFR) 53.243

The purpose of this amendment #A002 is to:

I. Delete from the solicitation, Section L - Instructions, Conditions, and Notices to Offers, 4.

Other Administrative Data, d. Adequate Accounting System in its entirety;

2. Par II-Contract Clauses, Section I-Contract Clauses, Article 1.. Additional Contract

Clauses, a. Federal Acquisition Regulation (FAR) (48 CFR Chapter I) Clauses is revised to add:

14. FAR Clause 52.44-5 Competition in Subcontracting (December 1996).

3. Section M- Evaluation Factors for Award, 3. Technical Evaluation Factors is revised to read as follows:

I. Documented experience of successful targeted gene insertion into iPSCs. publications. 20 points

2. Documented experience of successful targeted reporter gene insertion into iPSCs. 20 points

3. Documented standard protocols for iPSC targeted gene insertion. Provide a brief description of the technology and protocols used for iPSC targeted gene insertion. 20 points.

4. Expertise and documented experience with iPSC targeted gene insertion. Provide resumes or currculum vitae of individuals working on this contract. 20 points

5. Plans for the management of communications and coordination of progress and reporting. 10 points.

6. Adequacy of facilities and equipment. 10 points.

4. Provide the following responses to the questions asked by potential offerors:

QUESTION #1: Do subcontracts on these solicitations have to submit sealed bids or is it fine to include them within the Prime proposal? I didn't see anything in the RFP that stated sealed bids for subcontracts are required but I just wanted to confirm this.

RESPONSE #1: No subcontractors do not need to submit sealed bids. Please include the subcontractor's costs in with the Prime's proposaL.

QUESTION #2A: can you explain the criteria for the small business standard size $14M threshold referenced on pp. 24? Does this standard size refer to total revenues, anual revenue from federally sponsored projects, assets or some other measure?

NHLBI-CSB-(AR)-2012-018B-CRS / AMENDMENT #A002 / PAGE 2

RESPONSE #2A: For this paricular NAICS code the size standard is $14 milion. The $I4 milion is the average annual receipts for the past three years. A business wil not quality as a small business for this NAICS code if it is over $14 milion.

The definition of annual receipts is: Receipts means "total income" (or in the case of a sole proprietorship, "gross income") plus "cost of goods sold" as these terms are defined and reported on Internal Revenue Service tax retu forms. The term does not include net capital gains or losses; taxes collected for and remitted to a taxing authority if included in gross or total income, such as sales or other taxes collected from customers and excluding taxes levied on the concern or its employees; proceeds from transactions between a concern and its domestic or foreign affiliates; and amounts collected for another by a travel agent, real estate agent, advertising agent, conference management service provider, freight forwarder or customs broker. For size determination purposes, the only exclusions from receipts are those specifically provided for in this paragraph. All other items, such as subcontractor costs, reimbursements for purchases a contractor makes at a customer's request, and employee-based costs such as payroll taxes, may not be excluded from receipts. Receipts are averaged over a concern's latest three (3) completed fiscal years to determine its average annual receipts. If a concern has not been in business for three (3) years, the average weekly revenue for the number of weeks the concern has been in business is multiplied by 52 to determine its average anual receipts.

This SBA link may help you as well: http://www.sba.gov/content/small-business-size-standards

QUESTION #2B: Does an organization meet the criteria if the predominant source of revenue is from charitable contributions and is organized as a nonprofit SOL (c )(3)?

RESPONSE #2B: nonprofits are unable to be considered small business since they are not independently owned and operated.

QUESTION #3: Will there be a fee allowed in the proposed cost or any appropriate way for a commercial company to generate reasonable profit?

RESPONSE #3: A reasonable fee is allowable for commercial organizations.

QUESTION #4: Can we propose for only General Task i and Task 2, but not task 3 (i.e. we want to concentrate on generating iPS cell lines but not to propose on differentiation at this time)?

RESPONSE #4: No, you must propose on all three tasks.

QUESTION #5: In relation to Extent of Smaii Disadvantaged Business Participation, if we the applicant qualifies as small disadvantaged business, does it already fulfill the requirement under FAR Subpart 15.304(c)(4)?

RESPONSE #5: Yes, if the offeror qualifies as a Small Disadvantaged Business the requirement is fulfilled.

QUESTION #6: Can the same person be a principal investigator/project director on both these grants?

NHLBI-CSB-(AR)-2012-01SB-CRS / AMENDMENT #A002 / PAGE 3

RESPONSE #6: To clarify the type of contract, the awards wil be Indefinite-Delivery/Indefinite Quantity (IDIQ) contracts NOT a grant. The proposed principal investigator/project director can be the same.

All other terms and conditions of the solicitation remain unchanged.

The Contracting Specialist for this amendment is Robin Jeffres at (301) 435-0376 or email:

ro bin.j effr es(ênih. gov.

NHLBI-CSB-(AR)-2012-018B-CRS / AMENDMENT #A002 / PAGE 4