NCI SON _NanoZoomer.pdf

STATEMENT OF NEED (SON)

1.0 TITLE

One (1) Brand Name or Equal Acquisition of an automated NanoZoomer S60 Brightfield Whole Slide Scanner System

2.0 BACKGROUND

The National Cancer Institute's (NCI) Center for Cancer Research, Laboratory of Cancer Biology and Genetics depends on high-resolution digital slide scanners to analyze molecular markers in tissue samples. This technology enables researchers to use advanced imaging techniques and analysis tools, including computer vision and machine learning, to better understand cancer development and progression. The Molecular Pathology Unit (MPU) provides crucial support by delivering these high-quality digital images to researchers and facilitating their transfer to the NIH's digital image repository. However, the MPU's current scanners are obsolete and lack manufacturer support, jeopardizing their ability to provide these vital services. The acquisition of a replacement scanner is therefore critical to avoid disrupting ongoing and future research at the Laboratory.

3.0 BRAND NAME OR EQUAL

This requirement is for a Brand Name or Equal automated NanoZoomer S60 Brightfield Whole Slide Scanner System for Digital Pathology. The Federal Acquisition Regulation (FAR) provision 52.211-6 Brand Name or Equal (AUG 1999) is applicable to this requirement.

4.0 TYPE OF ORDER

This is a Firm Fixed-Price Purchase Order.

5.0 SPECIAL ORDER REQUIREMENTS

5.1 PRODUCT FEATURES/SALIENT CHARACTERISTICS

For this requirement the vendor must provide the Government with one (1) Brand Name or Equal NanoZoomer S60 Brightfield Whole Slide Scanner System as follow:

• The system must offer 20x and 40x scanning modes.

• The system must accommodate both standard 26 mm × 76 mm (thickness from 0.9 mm to

1.2 mm) and large 52 mm × 76 mm (thickness from 0.9 mm to 1.2 mm) slides.

• The system must provide a resolution of at least 0.46 μm/pixel (20x mode) and 0.23 μm/pixel

(40x mode).

• Slide image scan acquisition time must not exceed 2.5 minutes per slide.

• A manufacturer service contract must be available.

• The system must be upgradable to perform fluorescent optical scanning on the existing unit. This upgrade must include instrument-compatible operating software with multi-color (minimum 3) capability. The upgrade must also include an integration capability permitting overlay registration of brightfield and fluorescence image files.

• The system must allow for the simultaneous viewing of multiple slide images.

• The system must have a maximum automated scanning throughput of 60 or more slides.

• The system must offer operator-selected Z-stack image acquisition and depth interval adjustment capability.

• The system must provide unlimited user access to analysis and viewer software compatible with both MacOS and PC operating systems. Image viewing and analysis software must not require a license.

• The system's dimensions cannot exceed 28" D x 26.5" H x 26" W to fit in existing laboratory space.

• The system must be demonstrably compatible with existing NCI CBIIT cloud enterprise image storage and analysis software, including the NIH-wide platform Halo by IndicaLabs, to meet pathologist needs for telepathology and primary diagnosis. Image data file format, digital display rendering, and operability must be reliable and adaptable.

5.2 WARRANTY

In addition to the Implied warranty contained in FAR Clause 52.212-4, quoters are encouraged to provide express warranties. At a minimum, the Contractor shall provide a 12-month warranty or longer from date of final installation on all equipment and associated items provided under, or as a part of this purchase order. The warranty shall include repair and or replacement of parts, including travel, labor, and materials, at no additional cost to the Government. The warranty shall not exclude or limit the Governments rights for an implied warranty as established in the terms and conditions of clause 52.212-4.

5.3 DELIVERY / INSTALLATION

Delivery of all items quoted shall be delivered within forty-five (45) calendar days after receipt of order. All shipping/handling shall be FOB Destination, and delivery/installation fees shall be included in the quote. Upon delivery, the Contractor shall notify the respective NCI Technical Point of Contacts (TPOC), TBD at award, to schedule installation dates and times. Installation shall occur within five (5) business days of delivery, and shall be performed by, or under the direct supervision of, an Original Equipment Manufacturer (OEM) certified technician.

Equipment shall be delivered to and installed at the following address:

Item Description Delivery Address Date 1 One (1) Brand Name or

Equal NanoZoomer S60 Brightfield Whole Slide Scanner System

NIH/NCI/CCR/Laboratory of Cancer Biology & Genetics Building 37/Room 2002 37 Convent Dr.

Bethesda, MD 20892

45 Days after receipt of order

5.3.1 DELIVERY GUIDANCE

The Contractors shall communicate and follow instructions from the Technical Point of Contact (TPOC) to coordinate delivery, installation, and removal of trade-in equipment.

The Contractor shall direct all courier and delivery services – including those not operated by the Contractor (e.g. FedEx, USPS, UPS) – to follow the instructions in this section.

All companies delivering to the NIH main campus must comply with Commercial Vehicle Inspection Facility (CVIF) access procedures. Upon arrival, the CVIF will provide a list of buildings and loading docks to delivery personnel.

Deliveries will be logged in at the loading dock, and the loading dock contractor or Government personnel will attempt to contact the TPOC listed on the package. In the event that the TPOC is unable to accept the package, the delivery shall not be left at the loading dock station. The delivery must be returned to the Contractor, and the Contractor must coordinate with the TPOC to deliver on another date at no additional cost.

Deliveries can only be made between 8:00 a.m. and 4:00 p.m. EST, Monday – Friday, excluding federal holidays.

5.4 TRAINING

The Contractor shall provide one (1) training session for a minimum of five (5) NCI staff.

Training shall be on-site and shall take place within seven (7) days of equipment installation.

Training shall be facilitated by a factory-trained product specialist. Training will include an overview of setup approaches, maintaining instrument settings, establishing operational voltages, and software usage for custom instrument configurations, as well as a demonstration of the performance. All training expenses, including materials and/or travel expenses, shall be included in the quoted price.

6.0 TECHNICAL POINT OF CONTACT (TPOC)

The Technical Point of Contact/s (TPOC) is responsible for inspection and acceptance of all work in relation to this requirement and will serve as the Governments primary point of contact throughout the duration of the requirement. All efforts must be coordinated with this individual/s. The TPOC for this requirement is:

TBD (upon award)

Note: The TPOC has limited authority as defined within this Statement of Need. They do not have the authority to commit or obligate Government funds or make changes to the terms and conditions of the purchase order. As such, any changes to the purchase order must be performed by a warranted Government Contracting Officer with appropriate delegated authority to do so.