HT9425-25-RFI-LBA-03.pdf

Request for Information (RFI)

1. RFI Number: HT9425-25-RFI-LBA-03

2. RFI Title: EVOM TEER Measurement System

3. Agency: United States Army Medical Research Institute of Infectious Diseases

(USAMRIID)

4. Office: United States Army Medical Research Institute of Infectious Diseases

(USAMRIID)

5. Contracting Office: United States Army Medical Research Acquisition Activity (USAMRAA), Fort Detrick, Frederick, MD.

6. Location: Fort Detrick, Frederick, Maryland 21702

7. Background:

Virology and Bacteriology Divisions have an active Defense Threat Reduction Agency (DTRA) Joint Sciences and Technology Office (JSTO) project for use of organ tissue equivalent (OTE) transwells to conduct research against medical countermeasures. As part of this research, recording tissue electrical resistance of the transwell cell cultures provides cellular tight junction data required to ensure the quality of the model systems used in this project. TEER measurements are a phenotypic assay used to establish baseline parameters for acceptance criteria of the OTEs prior to moving forward with experimentation involving viruses and/or bacteria. The goal of this is to reduce variation between transwells and allow for more reproducible results.

USAMRIID is requesting to procure two (2) Epithelial Voltohmmeter (EVOM) Auto V3 Transepithelial Electrical Resistance (TEER) Measurement in 24C (Corning) High Throughput Screening (HTS) Systems. The systems shall measure cellular activity in real-time in a 24-well plate format that can accommodate Corning 24-well plates. The TEER measurement systems shall have automation, and the electrode array component shall be compatible for 24-well plates and have 4 pairs of electrodes. For full system functionality, the equipment shall include two (2) EVOM Auto V3 TEER Measurement in 24C HTS Plate systems, two (2) EVOM Auto 24C HTS Electrodearrays for TEER and on-site installation and training. The systems shall be covered under warranty for two (2) years commencing on the date of delivery. Refer to the Minimum Essential Characteristics (MECs) listed in Section 8.

8. Minimum Essential Characteristics:

The final package for this procurement should contain the following materials with all listed minimum essential characteristics being met:

The Virology and Bacteriology Divisions within USAMRIID request two (2) Epithelial Voltohmmeter (EVOM) Auto V3 Transepithelial Electrical Resistance (TEER)

Measurement in 24C (Corning) High Throughput Screening (HTS) Systems meeting the following MECs:

1. The auto measurement systems must have dimensions of approximately 16x10x 8.4”

2. The systems must have capability for 24-well high throughput screening.

3. The systems must include two (2) EVOM Auto 24C HTS Electrodearrays for

TEER.

4. The systems must measure cellular activity in real-time.

5. The systems must have automation for TEER measurement.

6. The systems must have compatibility for Corning 24-well plates.

7. The systems electrode array must contain an array of 4 pair of 1.2mm Φ electrodes.

8. The Contractor shall provide on-site installation and training of the systems.

9. The systems must be covered under warranty for two (2) years commencing on the date of delivery.

10. Shipping must be included.

Delivery Requirements:

Items shall be shipped to:

United States Army Medical Research Institute of Infectious Diseases (USAMRIID) 1425 Porter Street Fort Detrick, MD 21702

9. Information Requested in Capability Statement:

• Confirm availability of the requested products/training, as specified in the MECs.

• Provide verification that the company can provide the training and warranty as listed in the MECs.

10. North American Industry Classification System (NAICS) Code: The NAICS code for this potential action is: 334516, Analytical Lab Instrument Manufacturing

11. Response Due Date: Interested parties should submit their RFI response electronically by 12:00PM Eastern on 08 May 2025 via e-mail to Ms. Lindsey Arthur at lindsey.b.arthur2.civ@health.mil.

12. Instructions to Responders:

12.1 The Government appreciates responses from all capable and qualified sources.

12.2 The Government welcomes input and will accept questions pertaining to this RFI;

however, the Government reserves the right to answer or not answer all questions pertaining to this RFI. Only one set of questions per vendor will be accepted. Telephone requests will not be entertained.

mailto:lindsey.b.arthur2.civ@health.mil

12.3 The subject header of the e-mail for submission of questions and/or the RFI response shall be: HT9425-25-RFI-LBA-03.

12.4 Interested firms should submit a response (Capability Statement) that demonstrates the Offeror’s capabilities identified in this RFI. The Capability Statement shall not exceed five (5) typed pages; additional sheets for cover page, table of contents, tables, and charts will not be counted toward page limitation.

12.5 Fill in the below table when responding to this Sources Sought / RFI.

Question Answer RFI Number Company Name Company Address Point of Contact Phone Number E-mail Address Tax Identification Number (TIN) Cage Code

DUNS

Company Web Page Company Location(s) Company is / is not a Small Business Company is / is not SAM Registered Other Classifications (e.g. 8(a), HubZone, Woman-Owned, Veteran-Owned, Service- Disabled Veteran-Owned)

If 8(a), date that the company graduates from the program.

13. Disclaimer and Important Notes:

In accordance with Federal Acquisition Regulation (FAR) 15.201, "Exchange with industry before receipt of proposals," and FAR 52.215-3, "Request for information (RFI) or Solicitation for Planning Purposes (SFP)," this RFI is for information and planning purposes only, at this time, and shall not be construed as a solicitation or obligation on the part of the USAMRIID. The purpose of this RFI notice is to gain market knowledge.

This RFI is not expected to be a Request for Proposal or Invitation for Bid, nor does it restrict the Government to an ultimate acquisition approach. The Government is not obliged to award a contract or otherwise pay for the information provided in the responses received.

The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its responses are complete and sufficiently detailed to allow the Government to determine the organization's solution. Responders are advised that the Government is under no obligation to acknowledge receipt of the information received, or to provide feedback to respondents regarding any information submitted.

After a review of the responses received, a pre-solicitation synopsis and solicitation may be published on SAM.gov. At this time, no solicitation exists; therefore, please do not request a copy of the solicitation. NO PHONE CALLS PLEASE. It is the responsibility of any potential vendor to monitor SAM.gov for the release of any solicitation or synopsis.

Responses to this notice will not be considered adequate responses to a solicitation.

14. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in submitted responses. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).

Original Point of Contact (POC): Lindsey Arthur, lindsey.b.arthur2.civ@health.mil mailto:lindsey.b.arthur2.civ@health.mil