Amend_01-HHS-NIH-NIDA(MH)-14-272.pdf

OMB Approval 2700-0042

, 1. CONTRACT ID CODE rAG~ OF PAGES

AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT NIA I 2

2. AMENDMENT/MODIFICATION NO. 13. EFFECTIVE DATE 4. REQUISITION/PURCHASE REQ. NO.

15.

PROJECT NO. (If applicable)

Amendment One (01) 02/05/14 N/A N/A

6. ISSUED BY GODEi 7. ADMINISTERED BY (If other than Item 6) GODEi

National Institute of Mental Health (NIMH) R&D Contracts Section NIA/NIMH R&D Contracts Management Branch NIDA Neuroscience COAC, NIH, DHHS 6001 Executive Boulevard Room 8154, MSC 9661 Bethesda, MD 20892-9661

8. NAME AND ADDRESS OF CONTRACTOR (No. Street, County, State and ZIP: Code) {D) 9A. AMENDMENT OF SOLICITATION NO . ....__

RFP HHS-NIH-NIDA (MH) 14-272 x TITLE: "NIMH Toxicology Evaluation of Novel Ligands Program" 9B. DATED (SEE ITEM 11)

12/23/2013

TO: All Potential Offerors

10A. MODIFICATION OF CONTRACT/ORDER NO.

10B. DATED (SEE ITEM 13)

CODE I FACILITY CODE

11. THIS ITEM ONLY APPLIES TO AMENDMENTS OF SOLICITATIONS

IZ! The above numbered solicitation is amended as set forth in Item 14. The hour and date specified for receipt of Offers D is extended, IZ! is not extended.

Offers must acknowledge receipt of this amendment prior to the hour and date specified in the solicitation or as amended, by one of the following methods:

(a) By completing Items 8 and 15, and returning one (1) copy of the amendment; (b) By acknowledging receipt of this amendment on each copy of the offer submitted;

or (c) By separate letter or telegram which includes a reference to the solicitation and amendment numbers. FAILURE OF YOUR ACKNOWLEDGMENT TO BE RECEIVED AT THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERS PRIOR TO THE HOUR AND DATA SPECIFIED MAY RESULT IN REJECTION OF YOUR OFFER. If by virtue of this amendment you desire to change an offer already submitted, such change may be made by telegram or letter, provided each telegram or letter makes reference to the solicitation and this amendment, and is received prior to the opening hour and data specified.

12. ACCOUNTING AND APPROPRIATION DATA (If required)

13. THIS ITEM APPLIES ONLY TO MODIFICATIONS OF CONTRACTS/ORDERS,

IT MODIFIES THE CONTRACT/ORDER NO. AS DESCRIBED IN ITEM 14.

(D) A. THIS CHANGE ORDER IS ISSUED PURSUANT TO: (Specify authority) THE CHANGES SET FORTH IN ITEM 14 ARE MADE IN THE CONTRACT ORDER NO. IN ITEM 1 OA. -

B. THE ABOVE NUMBERED CONTRACT/ORDER IS MODIFIED TO REFLECT THE ADMINISTRATIVE CHANGES (such as changes in paying office, appropriation date, etc.) SET FORTH IN ITEM 14, PURSUANT TO THE AUTHORITY OF FAR 43.103(b).

C. THIS SUPPLEMENTAL AGREEMENT IS ENTERED INTO PURSUANT TO AUTHORITY OF:

D. OTHER (Specify type of modification and authority)

E. IMPORTANT: Contractor D is not, D is required to sign this document and return __ copies to the issuing office.

14. DESCRIPTION OF AMENDMENT/MODIFICATION (Organized by UCF section headings, including solicitation/contract subject matter where feasible.)

PURPOSE: To respond to solicitation questions.

(Continued on p. 2) Except as provided herein, all terms and conditions of the document referenced in Item 9A or 10A, as heretofore changed, remains unchanged and in full force and effect.

15A. NAME AND TITLE OF SIGNER (Type or print) 16A. NAME AND TITLE OF CONTRACTING OFFICER (Type or print)

15B. CONTRACTOR/OFFEROR

(Signature of person authorized to sign)

NSN 7540-01-152-8070

PREVIOUS EDITION UNUSABLE

Bruce E. Anderson Contracting Officer, OA, NIDA Neuroscience COAC

15C. DATE SIGNED 16B. UNITED STATES OF AMERICA 16C. DATE SIGNED

BY IJflM<e r ~ :2/ ~--11 '-/- 30-105

Computer Generated

(Signature of Contracting Officer)

STANDARD FORM 30 (REV. 10-83)

Prescribed by GSA FAR (48 CFR) 53.243

RFP HHS-NIH-NIDA (MH) 14-272

Amendment 01 February 5, 2014

Question 1:

For the AMES test that is required for costing (Ref. Attachment 4, page 6 of 6) are both Range Finding and Definitive studies required? (And for how many strains?)

NIMH Response 1:

Pricing should be for a definitive study, based on each offerer's proposed design for submission as part of an IND package. The number of strains should be decided upon and proposed by the offerer in the technical proposal.

Question 2:

Reference Attachment 3 - SOW - Page 7 of 14- Paragraph c(3): "The Contractor shall make information available about the NIMH Toxicological Evaluation of Novel Ligands Program at approximately 1-2 scientific meetings per year''

Please clarify if we should assume the travel costs should be included in Task 1 and the travel hours are included in the task total of 150 hours.

NIMH Response 2:

Yes, travel costs should be included in Task 1, and the hours included within the 150 hours.