FY25-SBIR-STTR-Phase-1-RFA-P.pdf

REQUEST FOR APPLICATIONS

Small Business Innovation Research and

Small Business Technology Transfer Programs Phase I

FUNDING YEAR: Fiscal Year (FY) 2025

LETTER OF INTENT DEADLINE: Not Applicable

APPLICATION DEADLINE: September 17, 2024

ANTICIPATED PROGRAM FUNDING: $13,000,000 for Small Business Innovation Research (SBIR) $2,500,000 for Small Business Technology Transfer (STTR)

AVERAGE INDIVIDUAL AWARD

RANGE: $125,000 - $181,500

FUNDING OPPORTUNITY NUMBER: USDA-NIFA-SBIR-010774

ASSISTANCE LISTING NUMBER: 10.212

INITIAL ANNOUNCEMENT

National Institute of Food and Agriculture United States Department of Agriculture

Assistance Listing Number (ALN): The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs Phase I is listed in the Assistance Listings under number 10.212.

Key Information 1: KEY DATES AND DEADLINES Application Deadline: 5:00 P.M. Eastern Time, September 17, 2024 Letter of Intent: Not Applicable Applicants Comments: Within six months from the issuance of this notice (NIFA may not consider comments received after the sixth month)

Advancing Diversity, Equity, Inclusion, and Accessibility (DEIA). The National Institute of Food and Agriculture (NIFA) recognizes research, education, and extension efforts will have the greatest impacts when programs are grounded in DEIA. NIFA is committed to enhancing diversity, equity, inclusion, and accessibility of programs and encourages individuals, institutions, and organizations from underserved communities to apply to funding opportunities as lead, co-lead, or subaward recipient(s), and to engage as leaders in the peer panel review process to support development of strong networks and collaborations. NIFA encourages applications that engage diverse communities and have broad impacts through research, education, extension, and integrated activities to address current and future challenges.

Stakeholder Input. NIFA seeks comments on all Request for Applications (RFA) so it can deliver programs efficiently, effectively, with integrity, and with a focus on customer service. NIFA considers comments to the extent possible when developing RFAs, and uses comments to help meet the requirements of Section 103(c)(2) of the Agricultural Research, Extension, and Education Reform Act of 1998 (7 U.S.C. 7613(c)(2)). Applicants may submit written comments to Policy@usda.gov. Please use the following subject line: Response to the Small Business Innovation Research and Small Business Technology Transfer Phase I RFA.

Climate Smart Agriculture. The United States Department of Agriculture (USDA) SBIR/STTR Programs administered by NIFA recognizes and is committed to supporting the USDA FY 2022- 2026 Strategic Goals, which include combating climate change in efforts to support America’s Working Lands, Natural Resources, and Communities. NIFA encourages the use of Climate Science Technology when appropriate to enhance projects.

https://uscode.house.gov/view.xhtml?req=(title:7%20section:7613%20edition:prelim)%20OR%20(granuleid:USC-prelim-title7-section7613)&f=treesort&edition=prelim&num=0&jumpTo=true mailto:Policy@usda.gov https://www.usda.gov/sites/default/files/documents/usda-fy-2022-2026-strategic-plan.pdf

EXECUTIVE SUMMARY

This RFA is being released prior to the passage of an appropriations act for FY 2025. Enactment of additional continuing resolutions, appropriations act, or other authorizing legislation may affect the availability or level of funding for these programs.

The amount available for Small Business Innovation Research (SBIR) Program Phase I in FY 2025 is approximately $13,000,000. The amount available for Small Business Technology Transfer (STTR) Program Phase I in FY 2025 is approximately $2,500,000. USDA is not committed to fund any particular application or to make a specific number of awards.

The USDA SBIR/STTR programs focus on transforming scientific discovery into products and services with commercial potential and/or societal benefit. Unlike fundamental research, the USDA SBIR/STTR programs support small businesses in the creation of innovative, disruptive technologies and enable the application of research advancements from conception into the market.

The STTR program aims to foster technology transfer through formal cooperative Research and Development (R&D) between small businesses and partnering research institutions.

Different from most other investors, the USDA SBIR/STTR Programs fund early or "seed" stage research and development that has a commercial potential. The programs provide equity-free funding and entrepreneurial support at the earliest stages of company and technology development.

Key differences between USDA’s SBIR and STTR programs include the percentage of research conducted by the partnering research institutions (e.g., Universities, Federal Laboratories) that requires a formal cooperative agreement detailing the allocation of intellectual property rights and rights, if any, to carry out follow-on research, development, or commercialization activities for STTR applicants and the primary employment of the project’s principal investigator.

This notice identifies the objectives for the SBIR and STTR Phase I projects, deadlines, funding information, eligibility criteria for projects and applicants, application forms and associated instructions, and review requirements.

TABLE OF CONTENTS

INITIAL ANNOUNCEMENT

KEY DATES AND DEADLINES

EXECUTIVE SUMMARY

KEY INFORMATION

PART I. FUNDING OPPORTUNITY DESCRIPTION

A. Legislative Authority B. Purpose and Priorities C. Program Area Descriptions

1. FORESTS AND RELATED RESOURCES – TOPIC 8.1

2. PLANT PRODUCTION AND PROTECTION (BIOLOGY) - TOPIC 8.2

3. ANIMAL PRODUCTION AND PROTECTION - TOPIC 8.3

4. CONSERVATION OF NATURAL RESOURCES - TOPIC 8.4

5. FOOD SCIENCE AND NUTRITION- TOPIC 8.5

6. RURAL AND COMMUNITY DEVELOPMENT - TOPIC 8.6

7. AQUACULTURE – TOPIC 8.7

8. BIOFUELS AND BIOBASED PRODUCTS - TOPIC 8.8

9. SMALL AND MID-SIZE FARMS – TOPIC 8.12

10. PLANT PRODUCTION AND PROTECTION (ENGINEERING) – TOPIC 8.13

PART II. AWARD INFORMATION

A. Available Funding B. Application Restrictions C. Project and Grant Types D. Ethical Conduct of Funded Projects

PART III. ELIGIBILITY INFORMATION

A. Eligibility Requirements B. STTR Partnering Research Institution Eligibility Criteria C. Cost Sharing or Matching

PART IV. APPLICATION AND SUBMISSION

A. Method of Application

Steps to Obtain Application Materials Help and Resources NIFA Support

B. Content and Form of the Application Key Application Instructions

C. Funding Restrictions Submission Dates and Times

PART V. APPLICATION REVIEW REQUIREMENTS

A. NIFA’s Evaluation Process B. Evaluation Criteria C. Proprietary Information

D. Rights in Technical Data E. Copyrights F. Patents and Inventions G. Research Involving Special Considerations H. Grantee Commitments I. Additional Information J. Organizational Management Information K. Application Disposition

PART VI. AWARD ADMINISTRATION

A. General B. Administrative and National Policy Requirements C. Expected Program Outputs and Reporting Requirements

PART VII. OTHER INFORMATION

A. Use of Funds and Changes in Budget B. Confidential Aspects of Applications and Awards C. Regulatory Information D. Limited English Proficiency

APPENDIX I: AGENCY CONTACT

APPENDIX II: GLOSSARY OF TERMS

APPENDIX III: DEFINITIONS

KEY INFORMATION

Key Information 1: KEY DATES AND DEADLINES Key Information 2: Forests and Related Resources Topic 8.1 Key Information 3: Plant Production and Protection (Biology) Topic 8.2 Key Information 4: Animal Production and Protection Topic 8.3 Key Information 5: Conservation of Natural Resources Topic 8.4 Key Information 6: Food Science and Nutrition Topic 8.5 Key Information 7: Rural and Community Development Topic 8.6 Key Information 8: Aquaculture Topic 8.7 Key Information 9: Biofuels and Biobased Products Topic 8.8 Key Information 10: Small and Mid-Size Farms Topic 8.12 Key Information 11: Plant Production and Protection (Engineering) Topic 8.13 Key Information 12: Comparison of Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Programs Key Information 13: Steps to Obtain Application Materials Key Information 14: Help and Resources Key Information 15: Key Application Instructions

PART I. FUNDING OPPORTUNITY DESCRIPTION

A. Legislative Authority The SBIR and STTR Extension Act of 2022, PUBLIC LAW 117–183—SEPT. 30, 2022, codified at 15 USC 638, reauthorizes and modifies the SBIR program, the STTR program, and related pilot programs through FY 2025.

The Federal agency with an SBIR or STTR program is required to assess the security risks presented by offerors with financial ties or obligations to certain foreign countries implemented through a Due Diligence Program. According to 15 U.S.C. 638(vv), agencies may not make awards to businesses with certain connections to foreign entities. To comply with this requirement, the program will require all SBIR/STTR Phase I applicants to complete additional certifications disclosing ties to foreign countries of concern at the time of application and as needed during the life of the funding agreement. Any questions regarding the Disclosure of Foreign Affiliations or Relationships to Foreign Countries Form should be emailed to sm.ddsbir@usda.gov.

These certifications will include:

1. The identity of all owners and covered individuals of the small business concern who are a party to any foreign talent recruitment program of any foreign country of concern.

2. The existence of any joint venture or subsidiary of the small business concern that is based in, funded by, or has a foreign affiliation with any foreign country of concern.

3. Any current or pending contractual or financial obligation or other agreement specific to a business arrangement, or joint venture-like arrangement with an enterprise owned by a foreign state or any foreign entity.

4. Whether the small business concern is wholly owned in a foreign country of concern.

5. The percentage, if any, of venture capital or institutional investment by an entity that has a general partner or individual holding a leadership role in such entity who has a foreign affiliation with any foreign country of concern.

6. Any technology licensing or intellectual property sales to a foreign country of concern, during the five-year period preceding submission of the proposal; and

7. Any foreign business entity, offshore entity, or entity outside the United States related to the small business concern.

The SBIR and STTR Extension Act of 2022 defines the term “foreign country of concern” to include “the People’s Republic of China, the Democratic People’s Republic of Korea, the Russian Federation, the Islamic Republic of Iran, or any other country determined to be a country of concern by the Secretary of State.”

The term “foreign talent recruitment program” or “malign foreign talent recruitment program” is defined in section 10632 of the CHIPS Act of 2022, 42 U.S.C. § 19237, Creating Helpful Incentives to Produce Semiconductors (CHIPS). Additional information may be found in the Guidance for Implementing National Security Presidential Memorandum 33 (NSPM-33) issued by the Office of Science and Technology Policy (OSTP).1

1 Available at https://www.whitehouse.gov/wp-content/uploads/2022/01/010422-NSPM-33-Implementation- Guidance.pdf.

https://www.congress.gov/117/plaws/publ183/PLAW-117publ183.pdf https://uscode.house.gov/view.xhtml?req=(title:15%20section:638%20edition:prelim)%20OR%20(granuleid:USC-prelim-title15-section638)&f=treesort&edition=prelim&num=0&jumpTo=true mailto:sm.ddsbir@usda.gov https://www.congress.gov/117/plaws/publ183/PLAW-117publ183.pdf https://www.congress.gov/bill/117th-congress/house-bill/4346/text https://www.federalregister.gov/documents/2023/03/07/2023-04660/request-for-information-nspm-33-research-security-programs-standard-requirement https://www.whitehouse.gov/wp-content/uploads/2022/01/010422-NSPM-33-Implementation-Guidance.pdf https://www.whitehouse.gov/wp-content/uploads/2022/01/010422-NSPM-33-Implementation-Guidance.pdf

NSPM-33 describes “Foreign government-sponsored talent recruitment program” as follows:

Effort organized, managed, or funded by a foreign government, or a foreign government instrumentality or entity, to recruit science and technology professionals or students (regardless of citizenship or national origin, or whether having a full-time or part-time position). Some foreign government-sponsored talent recruitment programs operate with the intent to import or otherwise acquire from abroad, sometimes through illicit means, proprietary technology or software, unpublished data and methods, and intellectual property to further the military modernization goals and/or economic goals of a foreign government. Many, but not all, programs aim to incentivize the targeted individual to relocate physically to the foreign state for the above purpose. Some programs allow for or encourage continued employment at United States research facilities or receipt of Federal research funds while concurrently working at and/or receiving compensation from a foreign institution, and some direct participants not to disclose their participation to United States entities. Compensation could take many forms including cash, research funding, complimentary foreign travel, honorific titles, career advancement opportunities, promised future compensation, or other types of remuneration or consideration, including in-kind compensation.

Further, SBIR/STTR Extension Act includes increased performance standards for more experienced SBIR/STTR firms regarding transition from Phase I to Phase II as well as commercialization benchmarks for Phase II awardees.

Additional guidance and program policy is provided by the Small Business Administration (SBA) through the SBIR/STTR Policy Directive.

B. Purpose and Priorities The SBIR and STTR programs are administered by NIFA on behalf of USDA. The SBIR and STTR program is listed in the Assistance Listing under 10.212. The program provides assistance to small-business concerns (SBC) to enable them to undertake and to obtain the benefits of research and development (R&D) in order to maintain and strengthen the competitive free enterprise system and the national economy.

SBIR/STTR are intended to support scientific excellence and technological innovation through the investment of Federal research funds to build a strong national economy by stimulating technological innovation in the private sector; strengthening the role of small business in meeting Federal research and development needs; increasing the commercial application of Federally supported research results; and fostering and encouraging participation by historically underserved and women-owned small businesses. Further, the objective of the STTR program is to stimulate formal cooperative partnerships of ideas and technologies between small businesses and partnering research institutions (e.g., Universities, Federal Laboratories). The USDA SBIR/STTR programs are therefore in a unique position to meet both the goals of USDA and the purpose of the SBIR/STTR legislation by transforming scientific discovery and innovation into both social and economic benefit and by emphasizing private sector commercialization.

Because the USDA programs currently have no specific procurement focus, USDA offers ten (10) solicitation topic areas that are intended to permit a broad spectrum of eligible and innovative science- and technology-based small businesses to compete for funding. The topics are detailed within Part I § C of this solicitation.

https://www.sbir.gov/about#policy-directive https://www.sbir.gov/about#policy-directive

These programs are subject to the provisions found at 7 CFR Part 3403. These provisions set forth procedures to be followed when submitting grant applications, rules governing the evaluation of applications and the awarding of grants, and regulations relating to the post-award administration of awarded projects.

The USDA SBIR/STTR programs are carried out in three separate phases. This program solicitation is only for the preparation and submission of SBIR/STTR Phase I applications. The aim of a Phase I project should be to demonstrate technical feasibility of the proposed innovation and thereby bring the innovation closer to commercialization. Proposals should describe the development of an innovation that demonstrates the following characteristics:

1. Involves a high degree of technical risk – for example, has never been attempted and/or successfully achieved and is still facing technical hurdles (that the USDA-funded R&D work is intended to overcome).

2. Has the potential for significant commercial impact and/or societal benefit as evidenced by having the potential to disrupt the targeted market segment; having good product-market fit (as validated by customers); removing barriers to entry for competition; and offering potential for societal benefit (through commercialization under a sustainable business model).

3. Phase I awards may not exceed the listed maximum award amount for each topic area (listed with specific Program Code) with a project period normally not to exceed eight (8) months for SBIR and twelve (12) months for STTR.

4. The Phase I application should concentrate on research that will significantly contribute to proving the scientific or technical feasibility of the approach or concept, describe the potential market for the innovation, and be a prerequisite to further USDA SBIR/STTR support in Phase II.

Only prior Phase I grant recipients are eligible to submit a Phase II application at the conclusion of the Phase I grant period to continue SBIR/STTR funding of the R&D and commercialization of the innovation. Phase II requires a more comprehensive application, outlining the proposed effort and commercialization strategy in detail. USDA SBIR/STTR typically announces the Phase II RFA in early December with a deadline in March. USDA NIFA recognizes that Phase I and II awards may not be sufficient in either dollars or time for the SBC to complete the total R/R&D and the commercialization activities required to bring the project results to a marketplace. Therefore, completion of the research under these circumstances may have to be carried into Phase III that derives from, extends, or logically concludes effort(s) performed under prior SBIR/STTR funding but is funded by sources other than the SBIR/STTR program, typically from the private sector. Phase III work is typically oriented towards commercialization of the SBIR/STTR innovation or technology.

The SBIR/STTR Phase I programs are aligned with the following USDA Strategic Goals FY 2022-2026:

Strategic Goal 1: Combat Climate Change to Support America’s Working Lands, Natural Resources and Communities and specifically addresses Objectives 1.1, 1.2, 1.3, and 1.4.

Strategic Goal 2: Ensure America’s Agricultural System is Equitable, Resilient, and Prosperous and specifically addresses Objectives 2.1, 2.2, and 2.3.

Strategic Goal 3: Foster an Equitable and Competitive Marketplace for All Agricultural Producers and specifically addresses Objectives 3.1 and 3.2.

Strategic Goal 4: Provide All Americans Safe, Nutritious Food and specifically addresses Objectives 4.1, 4.2, and 4.3.

https://www.ecfr.gov/current/title-7/part-3430

Strategic Goal 5: Expand Opportunities for Economic Development and Improve Quality of Life in Rural and Tribal Communities and specifically addresses Objectives 5.1, 5.2, 5.3, and 5.4.

The SBIR/STTR Phase I programs are aligned with the following USDA Science and Research Strategy, 2023–2026 priorities:

1. Priority 1: Accelerating Innovative Technologies & Practices

2. Priority 2: Driving Climate-Smart Solutions

3. Priority 3: Bolstering Nutrition Security & Health

4. Priority 4: Cultivating Resilient Ecosystems

Global Engagement. NIFA supports global engagement that advances U.S. agricultural goals.

NIFA recognizes that collaboration with international partners may be necessary to attain the agency's goals for U.S. agriculture, promote global competence of our nation’s future agricultural workforce, and promote safe and nutritious food security in a growing world. Therefore, although application to this RFA is limited to eligible U.S. institutions, applicants may collaborate with international partners, to include subcontracts to international partners or other institutions.

Applications must clearly demonstrate benefits to the U.S.

For a program informational webinar please visit the NIFA calendar for dates, event registration, and link. If you need a reasonable accommodation to participate in any of the informational webinars listed, please contact the event host listed no later than 10 days prior to the event.

C. Program Area Descriptions NIFA is soliciting applications under the following ten SBIR/STTR topics / program areas:

8.1 Forests and Related Resources

8.2 Plant Production and Protection (Biology)

8.3 Animal Production and Protection

8.4 Conservation of Natural Resources

8.5 Food Science and Nutrition

8.6 Rural and Community Development

8.7 Aquaculture

8.8 Biofuels and Biobased Products

8.12 Small and Mid-size Farms

8.13 Plant Production and Protection (Engineering)

1. FORESTS AND RELATED RESOURCES – TOPIC 8.1

Contact Dr. Diomides Zamora, NPL for SBIR/STTR Forests and Related Resources, at Diomides.Zamora@usda.gov or (202) 590-6049, regarding questions about the suitability of research topics or to arrange a consultation.

The Forests and Related Resources topic area aims to address the health, diversity, and productivity of the Nation’s forests and grasslands to meet the needs of present and future generations through the development of environmentally sound approaches to increase productivity of forest lands, improve sustainability of forest resources, and develop value-added materials derived from woody resources. New technologies are needed to enhance the protection https://www.usda.gov/sites/default/files/documents/usda-science-research-strategy.pdf https://www.usda.gov/sites/default/files/documents/usda-science-research-strategy.pdf https://nifa.usda.gov/calendar mailto:Diomides.Zamora@usda.gov of the Nation’s forested lands and forest resources and to help ensure the continued existence of healthy and productive forest ecosystems. Proposals focused on sustainable bioenergy and development of value-added biofuels from woody biomass and on the influence of climate change on forest health and productivity are encouraged. Proposals that utilize nanotechnology in their approach to developing new wood-based products or that utilize wood- based nanomaterials are also encouraged.

To meet the identified needs in forestry and wood utilization, the program’s long-term goals (10 years) are to achieve increased utilization of woody resources for value-added products from wood; healthy and sustainable forest ecosystems that are more resistant, resilient, and responsive to wildfires, the impact of pathogens and insects, and other disturbance events associated with climate change; improved environmental and economic methods of sustainable harvesting; and improved growth and yield of forest species that will lead to more efficient use of forested lands.

Key Information 2: Forests and Related Resources Topic 8.1

Program Code: 8.1 Program Code Name: Forests and Related Resources Assistance Listing Number: 10.212 Project Type: Research Grant Type: Standard Application Deadline: FY 2025: September 17, 2024, 5:00 P.M. Eastern Time Grant Duration: 8 Months SBIR | 12 Months STTR Anticipated Number of Awards: 6 Maximum Award Amount: $175,000 or $181,500 with Technical and Business Assistance

(TABA)

Forests and Related Resources Topic 8.1 - Other Key Information

a. Applicants are strongly encouraged to contact the NPL regarding the suitability of research topics by preparing a short summary of project ideas that is sent to the NPL prior to arranging a consultation for topic discussion.

b. Applications that deal with the development of biofuels derived from non-woody agricultural crops should be submitted under topic area 8.8 Biofuels and Biobased Products.

Forests and Related Resources Topic 8.1 - Research Priorities Examples of appropriate subtopics for research applications from small businesses include, but are not limited to the following:

a. Growth and Yield

Improving growing stock, tissue culture, genetic manipulation or vegetative reproduction of forest trees, and other means of increasing the regenerative abilities of forests; developing systems to increase the survival of newly planted trees through mechanical, physical or chemical means that are environmentally safe and through improved nutrient/water utilization;

reducing the adverse impact of pathogens and insects by developing better methods to monitor infestations and improving control strategies for combating insects and pathogens that attack important woody species.

b. Increasing the Utility of Forest-Grown Material Research to improve the yield of lumber, pulp fiber and specialty chemicals from trees; to utilize a greater percentage of the tree through improved techniques of production, for the creation of new or improved reconstituted products; to develop better methods for manufacturing wood-based products and testing products for performance and durability; and to develop improved methods to produce paper.

c. Reducing Ecological Damage by or Increasing Efficiency of Forest Operations Research to reduce soil erosion, compaction, water degradation or other alterations caused by harvesting and/or other forest operations; research on provisions and increasing efficiency of forest operations for the economic recovery of forest resources while raising or enhancing forest productivity and reducing ecological impacts.

d. Urban Forestry Research to promote the growth of forested land in urban areas, such as greenways, parks, and strategically planted urban trees, to address problems of forest fragmentation, the introduction of invasive species, and the impact of urban forested land on air and water quality and quality of life improvements.

e. Climate Change Research to address the issue of ecosystem adaptation to climate change, ways to enhance carbon sequestration and reduce greenhouse gas emissions (e.g., use of agroforestry and other forest management practices), development of decision support tools for forest managers to deal with various types of risks and uncertainties associated to climate change, and markets for forest ecosystem services.

f. Developing Technology that Facilitates the Management of Wildfires on Forest Lands Research that provides systems for detecting and managing wildfires; systems for reducing fuel loads in forests; research and technologies that address and promote production and protection of forest leading towards reduction of fuel build-up; tools and equipment for improving the efficacy and safety of fire fighters on the ground and in the air; and communication and navigation systems for improving the coordination of fire management activities.

g. Sustainable Bioenergy and Development of Value-Added Products from Forest Resources Research for development of improved methods for the conversion of forest lignocellulosic biomass into biofuels (e.g., ethanol, biobutanol, sustainable aviation fuel) and biobased products, including intermediate chemicals; development of new feedstock systems that address bioenergy needs while providing ecosystem services; development of new wood-based composite materials; development of local scale energy conversion projects that generate electricity and/or useful heat; and development of technologies that will mitigate carbon release from combustion.

2. PLANT PRODUCTION AND PROTECTION (BIOLOGY) - TOPIC 8.2

Contact Dr. Christopher Philips, NPL for SBIR/STTR Plant Production and Protection (Biology), at Christopher.Philips@usda.gov or (216) 390- 4211, regarding questions about the suitability of research topics or to arrange a telephone consultation.

The Plant Production and Protection (Biology) topic area will support research to examine novel ways of enhancing crop production and protection by developing new methods for plant improvement and pest management; new food and non-food crop plants through plant breeding;

diagnostic technologies for plant diseases; plant characteristics that reduce the harmful impact of plant pests, biotic, and abiotic stresses; new crop genotypes with characteristics that allow for their use in new commercial applications; and tools that address the health and success of domesticated and natural pollinators.

mailto:Christopher.Philips@usda.gov

Key Information 3: Plant Production and Protection (Biology) Topic 8.2 Program Code: 8.2 Program Code Name: Plant Production and Protection (Biology) Assistance Listing Number: 10.212 Project Type: Research Grant Type: Standard Application Deadline: FY 2025: September 17, 2024, 5:00 P.M. Eastern Time Grant Duration: 8 Months SBIR | 12 Months STTR Anticipated Number of Awards: 7 Maximum Award Amount: $175,000 or $181,500 with TABA

Plant Production and Protection (Biology) Topic 8.2 - Other Key Information

a. Applicants are strongly encouraged to contact the NPL regarding the suitability of research topics by preparing a short summary of project ideas that is sent to the NPL prior to arranging a consultation for topic discussion.

b. Phase I applications involving the development of transgenic crops would benefit by the inclusion of a brief description of the proposed path to commercialization, including an understanding of what will be needed to clear regulatory consideration. Phase II applications involving the development of transgenic crops should have an expanded section on how regulatory considerations will be met and market entry attained.

c. Applications that deal with non-biological engineering technologies should be submitted to topic area 8.13 Plant Production and Protection (Engineering).

d. Applications that deal with the genetic improvement and production of woody biomass feedstock crops should be submitted to topic area 8.1 Forest and Related Resources.

e. Applications that deal with the genetic improvement and production of algae should be submitted to topic area 8.7 Aquaculture.

Plant Production and Protection (Biology) Topic 8.2 - Research Priorities:

Research applications from small businesses should address one or more of the following:

a. Plant Improvement

Examples include, but are not limited to, improved crop production using traditional plant breeding and biotechnology to produce crops with new or improved quality, yield, agronomic, horticultural, value-added, resilience to climate change, or economic traits through techniques that can include, but are not limited to, molecular biology and mutagenesis, genomics, tissue culture, or embryogenesis; biological and/or technological approaches to improve the competitiveness of U.S. production; and development of new crop plants as sources of food, feedstocks for biobased products, or ornamental products.

b. Pollinators and Crop Production Examples include, but are not limited to, projects that develop and evaluate innovative tools and management practices to ensure healthy pollinators; provide alternative chemicals or biology-based strategies to combat varroa mites or key bee diseases; and develop, implement, or evaluate management practices of other crop pests/diseases that also ensure protection of pollinators.

c. Plant Protection Against Abiotic and/or Biotic Stresses Examples include, but are not limited to, risks and uncertainties associated with climate change; increasing plant resistance to plant pathogens, arthropod pests, and abiotic stress;

improved plant disease diagnostics for accurate, rapid, and cost-effective identification of causal agents; bio-based approaches to protect crops from insects, nematodes, and diseases;

and development of decision aid systems that are information extensive and time sensitive.

3. ANIMAL PRODUCTION AND PROTECTION - TOPIC 8.3

Contact Dr. Robert Smith, NPL for SBIR/STTR Animal Production and Protection, at Robert.M.Smith@usda.gov or (202) 445-3468, or Dr. Kathe Bjork, NPL for SBIR/STTR Animal Production and Protection, at Kathe.E.Bjork@usda.gov or (816) 591-7415, regarding questions about the suitability of research topics or to arrange a consultation.

Protein and other nutrients from animal sources are an important component of diets worldwide.

Agricultural animals also provide skins, fiber, feathers, and other products with economic importance. There is a growing need for these products as the global population expands and demand becomes higher. Fulfilling this need will require new technologies to improve both productivity and efficiency of food animals.

The Animal Production and Protection topic area aims to support the development of innovative, marketable technologies that will provide significant benefit to the production and protection of agricultural animals. New technologies for rapid detection, point-of-care, treatment, and prevention of disease are needed to improve productivity and enhance the biosecurity of our herds and flocks. Better technologies are also needed to develop and enhance alternatives to the use of antibiotics since pathogen resistance and human sensitivity to residue food products derived from animals have become of increasing concern. There is also an urgent need for technologies that decrease the impact of animal agriculture on the environment and optimize use of our natural resources, especially those that address carbon sequestration processes and provide an outlet for manure.

Technological advances in animal production and protection will not only enhance the safety of the Nation’s food supply and contribute to environmental stewardship, but they will also allow American producers to remain competitive in the global marketplace and contribute to global food security.

Key Information 4: Animal Production and Protection Topic 8.3 Program Code: 8.3 Program Code Name: Animal Production and Protection Assistance Listing Number: 10.212 Project Type: Research Grant Type: Standard Application Deadline: FY 2025: September 17, 2024, 5:00 P.M. Eastern Time Grant Duration: 8 Months SBIR | 12 Months STTR Anticipated Number of Awards: 7 Maximum Award Amount: $175,000 or $181,500 with TABA

Animal Production and Protection Topic 8.3 - Other Key Information proposals for this topic area by preparing a short summary of project ideas that is sent to the NPL prior to arranging a consultation for topic discussion.

b. Applications that deal with post-harvest technologies for foods derived from animals should be mailto:Robert.M.Smith@usda.gov mailto:Kathe.E.Bjork@usda.gov submitted under topic area 8.5 Food Science and Nutrition.

c. Applications that deal with mitigation of pollution through manure management should be submitted under topic area 8.4 Conservation of Natural Resources.

d. Applications that deal with transformation of manure or carcass waste into production of biofuels and biobased products should be submitted under topic area 8.8 Biofuels and Biobased Products.

e. Applications that deal with aquaculture species should be submitted under topic area 8.7 Aquaculture.

Animal Production and Protection Topic 8.3 - Research Priorities:

Development of marketable technologies designed for use in agriculturally important animals that will:

a. Improve Production Efficiency

Areas of interest include improved fertility; increased feed efficiency; and translation of genomic information into practical use and benefit.

b. Improve the Safety and/or Quality of End Products Derived from Animals These technologies must be applicable in the pre-harvest environment.

c. Improve Animal Health and Well-being Examples of these technologies include new rapid, more accurate, point-of-care oriented and competitively priced diagnostics, therapeutics, vaccines and other immunization methods, biosecurity management tools, traceability methods, and animal handling methods and developing alternatives to the use of antibiotics.

d. Improve the Productivity of Animals in Modified Conventional or Alternative Animal Production Systems Examples include non-confinement housing, pasture-based feeding systems, and organic systems.

e. Mitigate Climate Change and the Impacts of Animal Agriculture on the Natural Environment Areas of interest include technologies that decrease greenhouse gas emissions, improve carbon sequestration, or reduce the content of excretion of phosphorus and nitrogen and other nutrients in the manure or excreta, but does not include manure management.

4. CONSERVATION OF NATURAL RESOURCES - TOPIC 8.4

Contact Dr. Sandeep Kumar, NPL for SBIR/STTR Conservation of Natural Resources, at Sandeep.Kumar@usda.gov or (816) 832-7235, regarding questions about the suitability of research topics or to arrange a consultation.

The goal of the Conservation of Natural Resources topic area is to commercialize innovative technologies that are developed with the purpose to conserve, monitor, improve, and/or protect the quality and/or quantity of natural resources and reduce potential waste streams while sustaining climate-smart, optimal farm and forest productivity and profitability. The objective of this topic area is the conservation of soil, water, air, and other natural resources on landscapes that produce agricultural, natural, and forest/rangeland goods and services. New technologies and innovations applying circular agriculture principles that will make use of waste or byproducts, help improve soil health, reduce soil erosion, improve water and air quality, improve nutrient management, and conserve and use water more effectively are encouraged.

mailto:Sandeep.Kumar@usda.gov

Key Information 5: Conservation of Natural Resources Topic 8.4 Program Code: 8.4 Program Code Name: Conservation of Natural Resources Assistance Listing Number: 10.212 Project Type: Research Grant Type: Standard Application Deadline: FY 2025: September 17, 2024, 5:00 P.M. Eastern Time Grant Duration: 8 Months SBIR | 12 Months STTR Anticipated Number of Awards: 9

Conservation of Natural Resources Topic 8.4 – Other Key Information topics by preparing a short summary of project ideas that is sent to the NPL prior to arranging a consultation for topic discussion.

b. Applications that include software development or other data-intensive technologies are encouraged to apply to other topic areas listed within this request for applications.

c. Applicants should demonstrate that the proposed technology is innovative and not redundant with what is currently available. If similar technologies exist, please provide a comparison table contrasting your technology with others.

d. Applications that address animal manure or carcass waste to produce biofuels and biobased products should be submitted to topic area 8.8 Biofuels and Biobased Products.

e. Technologies for the rapid detection of food borne hazards (microorganisms, chemicals, toxins) during pre- and post-harvest processing and distribution should be submitted to topic area 8.5 Food Science and Nutrition.

Conservation of Natural Resources Topic 8.4 - Research Priorities:

not limited to, the following:

a. Water Quality and Quantity

Develop new and innovative technologies to improve water management and conservation at the farm- and watershed-scales and monitor the quality of surface water and groundwater resources for biotic and abiotic pollutants (e.g. PFAS and microplastics). Create improved technologies focused on the use of nontraditional water sources (treated wastewater, agricultural return flows and produced water from minerals extraction) for agricultural irrigation and improve irrigation technologies to provide superior timing, distribution and cost-effective delivery of water and chemicals for the optimal growth of agricultural products and natural and forest/rangeland goods and services.

b. Soil Health Research topics may include soil nutrient content, microbial functional activity related to nutrient cycling, methods to remediate degraded soils, methods to monitor and increase soil carbon storage capacity, mitigation of PFAS and microplastic contaminants, and methods for monitoring and preventing soil erosion by wind and water.

c. Air Resources Develop new and improved technologies to monitor air quality and reduce air pollution stemming from agricultural enterprises, including manure from livestock and poultry production systems, dust, and methane capture for use on-farm or off-farm.

d. Nutrient Management Develop new and improved technologies to extract and utilize nutrients and macro- and micronutrient management practices that help maximize plant productivity while minimizing negative environmental impacts.

5. FOOD SCIENCE AND NUTRITION- TOPIC 8.5

Contact Dr. Jodi Williams, NPL for SBIR/STTR Food Science and Nutrition, at Jodi.Williams@usda.gov or (202) 424-9722, regarding questions about the suitability of research topics or to arrange a consultation.

The Food Science and Nutrition topic area aims to fund projects that support research focusing on developing new and improved processes, technologies, products, or services that address emerging food safety, food processing, and nutrition issues. The program will fund projects to: 1) increase the understanding of the physical, chemical, and biological properties of food; 2) improve methods for the processing and packaging of food products to improve the quality, safety and nutritional value of foods, and to reduce food waste; 3) develop systems and technologies for rapid, sensitive, reliable and robust detection of pathogens and chemical hazardous materials in foods across the food supply chain, including systems that utilize artificial intelligence and blockchain technology; 4) develop programs or products that encourage the consumption of healthy foods and reduce diet related chronic diseases, or alleviate urban and rural food deserts;

and 5) develop products to drive climate-smart food systems to ensure a safe, accessible and nutritious food supply. The outcome of a successful project is a proof of concept for a marketable product or patented process.

The long-term goals (10 years) of the program are to commercialize production of novel food products, processes, materials, and systems that reduce foodborne illness, reduce the food industry’s carbon footprints, improve nutrition and health, enhance the nutritional quality and value of foods, and/or bridge socioeconomic gaps to increase the accessibility of healthy, sustainably produced foods.

Key Information 6: Food Science and Nutrition Topic 8.5

Program Code: 8.5 Program Code Name: Food Science and Nutrition Assistance Listing Number: 10.212 Project Type: Research Grant Type: Standard Application Deadline: FY 2025: September 17, 2024, 5:00 P.M. Eastern Time Grant Duration: 8 Months SBIR | 12 Months STTR Anticipated Number of Awards: 11

Food Science and Nutrition Topic 8.5 - Other Key Information topics by preparing a short summary of project ideas that is sent to the NPL prior to arranging a consultation for topic discussion.

b. Projects that implement blockchain based systems that can be easily integrated into different stages of the food supply chain to create transparent, accessible, and real-time information mailto:Jodi.Williams@usda.gov about the products origin, processing, and distribution are encouraged.

c. New rapid detection tests should be designed to detect at least 1 cfu/25g of food using approaches that reduce or eliminate enrichment and should be designed to allow for sampling large volumes of food.

d. Projects that promote value-added products and processes are encouraged.

e. Projects that utilize artificial intelligence are encouraged.

f. Projects that address functional foods to promote health are encouraged.

g. Projects that focus on technologies for improving cost benefit and model-based analyses, including distribution, warehousing, and retailing systems as they relate to the economy are acceptable.

h. Consumer focused projects to reduce post-harvest food losses and food waste are encouraged.

i. Projects that exclusively focus on nutritional supplements rather than food ingredients will not be considered.

j. Projects focused on the pre-harvest systems (including soil nutrient and water content and/or air quality) rather than human health outcomes should be submitted to topic area 8.4 Conservation of Natural Resources.

k. Projects should include appropriate collaborations with experts in the field of investigation (e.g., a food scientist or nutritionist as a part of the development team for the project).

Food Science and Nutrition Topic 8.5 - Research Priorities:

not limited to, the following:

a. Food Safety

Developing sustainable technologies for detection or mitigation of foodborne hazards (biological, chemical, intentional, or unintentional) during pre- and post-harvest processing and distribution.

b. Food Quality-Engineering Developing innovative processing, packaging, and sanitation technologies or materials that reduce post- harvest losses in foods and food waste while maintaining safety, quality, and nutrition and/or extending shelf life of the product.

c. Food Quality-Science Understanding the physical, biological, and chemical interactions and functionality of food in order to develop affordable food ingredients and/or food formulations that contribute to the development of high-quality foods.

d. Nutrition-Education Developing and implementing effective programs that provide equitable access to nutritious food in schools and through youth programs. Program audiences may include educators, parents, or community health workers to foster healthy nutritional choices to combat diet-related chronic diseases.

e. Nutrition-Science Improve functionality and efficacy of foods, nutrients, and/or dietary bioactive components in promoting and sustaining health. Strategies to promote and sustain health may include synthesizing available data in a responsible and ethical manner to develop personalized recommendations.

f. Nutrition Security, Food Safety, and Quality Data Tools Development of portable tools and technologies that collect and analyze food intake, nutrient data, food safety, and food quality data to enable producers, consumers, and retailers to make healthy choices and/or alleviate food deserts to support a resilient food system.

6. RURAL AND COMMUNITY DEVELOPMENT - TOPIC 8.6

Contact Dr. Edwin Lewis for SBIR/STTR Rural and Community Development at Edwin.Lewis@usda.gov or (817)-542-3306, or Dr. Keith Harris, NPL for SBIR/STTR Rural and Community Development, at Keith.Harris@usda.gov or (816) 589-6631, regarding questions about the suitability of research topics or to arrange a consultation.

The objective of the Rural and Community Development topic area is to improve the quality of life and standard of living in rural communities by creating and commercializing technologies that address important economic and social development issues or challenges in rural America.

Projects must explicitly discuss the specific rural problem or opportunity that will be examined and how the proposed science-based technology will successfully address the problem or opportunity. Applications must also include an objective to assess the impacts of the proposed project on protecting or enhancing the environment, on climate mitigation or adaptation, or the socio-economic development of rural areas. The applications need not be centered on agriculture but may be focused on any area that has the potential to provide significant benefit to rural Americans. USDA seeks a balanced portfolio that appropriately mixes high risk, high reward innovations with new applications of existing technologies that advance environmental justice and alleviate environmental hazards in overburdened communities of concern.

Key Information 7: Rural and Community Development Topic 8.6

Program Code: 8.6 Program Code Name: Rural and Community Development Assistance Listing Number: 10.212 Project Type: Research Grant Type: Standard Application Deadline: FY 2025: September 17, 2024, 5:00 P.M. Eastern Time Grant Duration: 8 Months SBIR|12 Months STTR Anticipated Number of Awards: 9 Maximum Award Amount: $125,000 or $131,500 with TABA

Rural and Community Development Topic 8.6 – Other Key Information topics by preparing a short summary of project ideas that is sent to the NPL prior to arranging a consultation for topic discussion.

b. Because this topic area addresses impact on rural communities, community letters of support are encouraged.

c. Projects are expected to be science-based and enhance the environmental and economic vitality of rural communities. Applications must contain an objective to assess the impacts of the proposed project on the environment or the socio-economic development of rural areas.

d. Projects are expected to provide evidence of the rural market to be served. PDs should identify any barriers to commercialization and discuss how they propose to address them during this and all future phases.

e. Applications dealing with on-farm production agriculture research should be submitted to topic area 8.12 Small and Mid-Size Farms.

f. Applications dealing with the development of biofuels and biobased products should be submitted to topic area 8.8 Biofuels and Biobased Products.

g. Applicants should demonstrate that the proposed technology is innovative and not redundant mailto:Edwin.Lewis@usda.gov mailto:Keith.Harris@usda.gov with what is currently available. If similar technologies exist, please provide a comparison table contrasting your technology with others.

Rural and Community Development Topic 8.6 – Research Priorities:

not limited to, the following:

a. Development of Services, Information, and Managerial Systems that Improve the Efficiency and Effectiveness of Local Governments and Public and Private Institutions Topics may include educational programs, including virtual platforms, apps, and gaming, which address the specific needs of people in rural areas…