FOA PUBLICATION CDC-RFA-PS17-1712.pdf

Image Description: Centers for Disease Control

Centers for Disease Control

National Center for HIV-AIDS, Viral Hepatitis, STD, and TB Prevention

Assuring Comprehensive Prevention and Treatment for Families Affected by HIV to Eliminate Perinatal HIV Transmission in the United States

CDC-RFA-PS17-1712

Application Due Date: 06/12/2017

Assuring Comprehensive Prevention and Treatment for Families Affected by HIV to Eliminate Perinatal HIV Transmission in the United States

CDC-RFA-PS17-1712

TABLE OF CONTENTS

Part I. Overview Information Federal Agency NameA.

Funding Opportunity TitleB.

Announcement TypeC.

Agency Funding Opportunity NumberD.

Catalog of Federal Domestic Assistance (CFDA) NumberE.

Dates F.

Executive Summary G.

Part II. Full Text Funding Opportunity Description A.

Award Information B.

Eligibility Information C.

Application and Submission Information D.

Review and Selection Process E.

Award Administration Information F.

Agency Contacts G.

Other Information H.

Glossary I.

Part I. Overview Information Applicants must go to the synopsis page of this announcement at www.grants.gov and click on the "Send Me Change Notifications Emails" link to ensure they receive notifications of any changes to CDC-RFA-PS17-1712. Applicants also must provide an e-mail address to www.grants.gov to receive notifications of changes.

A. Federal Agency Name:

Centers for Disease Control and Prevention (CDC) / Agency for Toxic Substances and Disease Registry

(ATSDR)

B. Funding Opportunity Title:

Assuring Comprehensive Prevention and Treatment for Families Affected by HIV to Eliminate Perinatal HIV Transmission in the United States C. Announcement Type: New - Type 1 This announcement is only for non-research activities supported by CDC. If research is proposed, the application will not be considered. For this purpose, research is defined at https://www.gpo.gov/fdsys/pkg /CFR-2007-title42-vol1/pdf/CFR-2007-title42-vol1-sec52-2.pdf. Guidance on how CDC interprets the definition of research in the context of public health can be found at http://www.cdc.gov/od/science/integrity /docs/cdc-policy-distinguishing-public-health-research-nonresearch.pdf.

New-Type 1

D. Agency Funding Opportunity Number:

CDC-RFA-PS17-1712

E. Catalog of Federal Domestic Assistance (CFDA) Number:

93.939 F. Dates:

1. Due Date for Letter of Intent (LOI): N/A

2. Due Date for Applications: 06/12/2017, 11:59 p.m. U.S. Eastern Standard

Time, at www.grants.gov.

LOI is not requested or required as part of the application for this FOA.

3. Date for Informational Conference Call:

N/A

G. Executive Summary:

1. Summary Paragraph:

To maintain and improve upon gains in the prevention of perinatal HIV transmission in the United States and to improve the continua of HIV prevention and HIV care for women of childbearing age, this FOA has a number of goals. The awardee will collaborate with CDC to update the Framework for the Elimination of Mother-to-Child HIV Transmission in the United States and increase the awareness of clinicians and public health professionals about it. They will increase the number of state and local health departments describing progress in the elimination of perinatal HIV infections by developing and disseminating model strategies for jurisdictions to describe their progress using measures from the updated Framework. They will increase the knowledge among health care providers and public health professionals about the interaction of, and essential role of HIV care for adults in the prevention of perinatal HIV transmission. And they will further the implementation of the updated Framework by convening a stakeholder group to develop and implement https://foa.grantsolutions.gov/www.grants.gov https://foa.grantsolutions.gov/www.grants.gov https://www.gpo.gov/fdsys/pkg/CFR-2007-title42-vol1/pdf/CFR-2007-title42-vol1-sec52-2.pdf https://www.gpo.gov/fdsys/pkg/CFR-2007-title42-vol1/pdf/CFR-2007-title42-vol1-sec52-2.pdf http://www.cdc.gov/od/science/integrity/docs/cdc-policy-distinguishing-public-health-research-nonresearch.pdf http://www.cdc.gov/od/science/integrity/docs/cdc-policy-distinguishing-public-health-research-nonresearch.pdf http://www.grants.gov action plans as well as share best practices and educational content to a large network of relevant professionals.

a. Eligible Applicants: Open Competition

b. FOA Type: Cooperative Agreement

c. Approximate Number of Awards: 1

d. Total Project Period Funding: $2,000,000

e. Average One Year Award Amount: $400,000

f. Total Project Period Length: 5

g. Estimated Award Date: 09/29/2017

h. Cost Sharing and / or Matching Requirements: N Cost sharing or matching funds is not required for this program. Although no statutory matching requirement for this FOA exists, leveraging other resources and related ongoing efforts to promote sustainability is strongly encouraged.

Part II. Full Text A. Funding Opportunity Description

Part II. Full Text

1. Background

a. Overview The annual number of children with diagnosed perinatally acquired HIV infection has steadily declined since the late 1990s, such that in 2008, elimination of perinatal HIV infection in the United States was considered by a group of experts as an achievable goal, and two targets for elimination were recommended: 1) a perinatal transmission rate < 1% among live infants born to women living with HIV, and 2) a perinatal HIV incidence rate < 1 per 100,000 live births.

In 2012, CDC published a Framework for the Elimination of Mother to Child HIV Transmission (EMCT) in the United States, and through CDC cooperative agreement PS12-1206, convened a group of stakeholders to develop and facilitate its implementation. Based on the latest national data, elimination of perinatal HIV transmission (EMCT) may have occurred in the United States: in 2013, an estimated 69 infants with HIV infection were born in the United States, an estimated incidence of approximately 1.7/100,000 live-births.

The possibility that the nation is in the elimination phase of perinatal HIV in the U.S. raises several questions: What criteria are necessary to support the assessment? Does CDC need to alter its approach to prevention? Are the activities required for elimination different from those required for maintenance of it?

How does CDC sustainably integrate the required activities into the preventive and therapeutic programs for adults? After considering these and other questions, it might be necessary to alter the existing EMCT Framework. In particular, it may be necessary to anticipate a change in perception about perinatal HIV transmission in the aftermath of asserting its elimination. At a minimum, it will be necessary to maintain the achievement of elimination. While doing this, it might be advisable to align concerns about perinatal HIV transmission more with those concerning HIV care for adults as well as those concerning the prevention of other perinatal infections. There are additional considerations. Recent information from the Fetal and Infant Mortality Review (FIMR)/HIV Methodology suggests that issues regarding mental health and substance abuse are prominent among the ongoing cases of perinatal HIV transmission. In addition, racial/ethnic disparities remain starkly apparent and require constant attention even as overall numbers decline. Finally, as considerations of perinatal HIV transmission evolve in this era, it will be necessary to maintain a workforce capable of dealing with the many issues. These considerations and the lessons learned from the workforce capable of dealing with the many issues. These considerations and the lessons learned from the Stakeholders’ Group and work done in other countries suggest that CDC should review the targets for elimination of perinatal HIV transmission, and update the Framework. This FOA will contribute to maintaining the gains in perinatal HIV prevention and perhaps further decrease the annual number of perinatal HIV infections, by expanding upon the work of the previous stakeholders group. It also will contribute to improvements in maternal and child health along the HIV prevention and care continuums and work to integrate mental health and substance abuse treatment services with HIV care for families.

b. Statutory Authorities This program is authorized under Section 301(a) of the Public Health Service Act (42 U.S.C. section 241(a).

c. Healthy People 2020 This FOA addresses Healthy People 2020 objectives: HIV-8.1 Reduce newly diagnosed perinatally acquired HIV cases, HIV-13 Increase the proportion of persons living with HIV who know their serostatus, HIV-14.3 Increase the proportion of pregnant women who have been tested for HIV in the past 12 months, and HIV-20 Increase the proportion of persons with an HIV diagnosis who had at least one HIV medical care visit in each 6 month period of the 24 month measurement period, with a minimum of 60 days between medical visits.

https://www.healthypeople.gov/2020/topics-objectives/topic/hiv/objectives

d. Other National Public Health Priorities and Strategies This FOA addresses 3 goals of the National HIV/AIDS Strategy: Updated to 2020: https://www.aids.gov /federal-resources/national-hiv-aids-strategy/nhas-update.pdf

Goal 1: Reducing new HIV infections

Step 1.B.2: Support and strengthen integrated and patient-centered HIV and related screening (sexually transmitted infections [STI], substance use, mental health, intimate partner violence, viral hepatitis infections) and linkage to basic services (housing, education, employment).

Goal 2: Increasing access to care and improving health outcomes for people living with HIV

Goal 3: Reducing HIV-related disparities and health inequities

In addition, this FOA addresses 3 goals of the National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention Strategic Plan Through 2020:

Goal 1: Decrease incidence of infection with HIV, viral hepatitis, STDs, and TB.

Goal 2: Decrease morbidity and mortality from HIV, viral hepatitis, STDs, and TB

Goal 3: Decrease health disparities across groups affected by HIV, viral hepatitis, STDs, and TB.

e. Relevant Work This FOA builds upon the work done in FOA-CDC-PS-12-1206 “Implementing a National Framework to Eliminate Mother-to-Child HIV Transmission in the United States.”

2. CDC Project Description

a. Approach

Bold indicates project period outcome.

CDC-RFA-PS17-1712Logic Model:Assuring Comprehensive Prevention and Treatment for Families Impacted by HIV to Eliminate Perinatal HIV Transmission in the United States

Bold indicates outcomes that will be measured https://www.healthypeople.gov/2020/topics-objectives/topic/hiv/objectives https://www.aids.gov/federal-resources/national-hiv-aids-strategy/nhas-update.pdf https://www.aids.gov/federal-resources/national-hiv-aids-strategy/nhas-update.pdf

Strategies and Activities Short-term Outcomes Intermediate Outcomes Long-Term Outcomes

Update CDC’s Framework for the Elimination of Mother-to-Child HIV Transmission (EMCT).

Develop and disseminate strategies for jurisdictions to describe progress in elimination of perinatal HIV infection using measures identified in updated EMCT Framework

Convene a stakeholder group representing a broad network of public health professionals and clinical care providers to implement the updated EMCT Framework.

-Include a work group to address the challenges of mental health and substance use disorders among families affected by HIV.

Develop educational and best-practice-sharing networks of the perinatal HIV prevention workforce including clinical care providers and public health professionals.

Increase awareness among clinicians of the updated EMCT Framework

Increase number of state and local health departments describing progress in elimination of perinatal HIV infections

Increase knowledge among providers about the interaction of HIV care of adults and prevention of perinatal HIV transmission.

Increase expertise among HIV care providers on EMCT Framework.

Increase access to substance abuse treatment and mental health services for pregnant and post-partum women.

Maintain the gains (e.g., low number of infections) in prevention of perinatal HIV transmission.

Improve maternal and child health along the HIV prevention and HIV care continuums.

Improved continuum of HIV care for women of child-bearing age and heterosexual men, including integrating mental health and substance abuse treatment services.

Decrease perinatally acquired HIV infections

i. Purpose To maintain the gains in the prevention of perinatal HIV transmission in the United States and to improve maternal and child health along the HIV prevention and care continuums, this project will update CDC’s Framework for the Elimination of Mother-to-Child HIV Transmission, develop strategies for jurisdictions to describe progress in elimination of perinatal HIV infection, convene a group of stakeholders representing to implement the updated Framework, and develop broader educational and best-practice-sharing networks.

ii. Outcomes As outlined in the logic model, the following are the outcomes the awardee is expected to both achieve and

As outlined in the logic model, the following are the outcomes the awardee is expected to both achieve and measure during the project period:

Increase awareness among clinicians of the updated EMCT Framework;

Increase number of state and local health departments describing progress in elimination of perinatal HIV infections;

Increase knowledge among providers about the interaction of HIV care of adults and prevention of perinatal HIV transmission; and Maintain the gains (e.g., low number of infections) in prevention of perinatal HIV transmission.

iii. Strategies and Activities The awardee will be expected to use the following strategies and activities to achieve the programs expected outcomes:

Update CDC’s Framework for the Elimination of Mother-to-Child HIV Transmission (EMCT):

Collaborate with CDC to update the EMCT Framework and to update target numbers for elimination of perinatal HIV transmission.

Plan, support and facilitate consultation meetings to inform update of the EMCT Framework.

Prepare a report of the consultants’ perspectives and opinions regarding elimination of perinatal HIV transmission.

Collaborate with CDC on a manuscript on updated EMCT Framework.

Disseminate the updated framework to relevant clinical and public health audiences.

Develop and disseminate strategies for jurisdictions to describe progress in elimination of perinatal HIV infection using measures identified in updated EMCT Framework

Engage with public health HIV prevention program and HIV surveillance experts to develop strategies.

Distribute strategies to HIV prevention and HIV surveillance programs.

Convene a stakeholder group representing a broad network of public health professionals and clinical care providers to implement the updated EMCT Framework.

Host at least one annual meeting of the stakeholder group.

Establish and staff 5-6 work groups based on updated EMCT Framework to develop workgroup-specific action plans and provider tools. One of the work groups should address the challenges of mental health and substance use disorders among families affected by HIV.

Host sub-group meetings for developing and disseminating strategies to integrate care for HIV, mental health and substance abuse treatment.

Engage stakeholder group network to disseminate action plans and tools using member organizational networks.

Develop educational and best-practice-sharing networks of the perinatal HIV prevention workforce including clinical care providers and public health professionals.

Conduct at least one annual webinar/educational event with each network group. Potential Network Groups might include:

Obstetricians (American Congress of Obstetricians and Gynecologists, Society for Materal-Fetal Medicine) Pediatricians (American Academy of Pediatrics) Ryan White Program grantees CDC HIV prevention program and surveillance grantees Title X Program providers (Office of Population Affairs) AIDS Education and Training Centers faculty

Maternal and Child Health public health professionals (Association of Maternal and Child Health Programs and CityMatCH) Clinical subject matter experts in perinatal HIV prevention Providers of HIV care for adults (American Academy of HIV Medicine, HIV Medicine Association) Substance Abuse and Mental Health Services Administration grantees working with pregnant and post-partum women

Apply to conduct an institute at the Ryan White Program Grantees Meeting on the updated Framework and action plans and provider tools to eliminate perinatal transmission and improvement in care and prevention services for women.

1. Collaborations

a. With other CDC programs and CDC-funded organizations:

Applicants must describe how they will collaborate with CDC staff in the Division of HIV/AIDS Prevention as well as CDC-funded state and city health departments HIV prevention and HIV surveillance programs.

b. With organizations not funded by CDC:

Applicants must provide at least twelve letters of support (LOS) with at least four from each of three categories of stakeholders. The three categories of stakeholder agencies and organizations are: 1) local and national organizations, 2) health departments, and 3) academic institutions. A listing of organizations in each category is available at: https://www.cdc.gov/hiv/group/gender/pregnantwomen/organizations.html .

Applicants must file the letters of support, name the file “LOUs”, and upload it as a PDF file at www.grants .gov.

2. Target Populations The applicant should include people with disabilities, e.g., persons living with HIV in the target population as well as in key aspects of the project (e.g., advisory boards, planning committees, project staff, consultants, etc.). Where appropriate, applicants are encouraged to also include: tribal organizations; rural populations;

non-English speaking populations; lesbian, gay, bisexual, and transgender (LGBT) populations; and people with limited health literacy. Applicants should describe how they will include women of childbearing age who are living with HIV when they plan, implement and evaluate their program. For additional information about disability inclusion, go to: http://www.cdc.gov/ncbddd/disabilityandhealth/disability-inclusion.html .

a. Health Disparities Applicants should describe how their proposed activities will benefit persons living with HIV and how they will reduce the HIV-related health disparities, e.g., the disparities in rates of HIV infection among racial and ethnic minority groups.

iv. Funding Strategy N/A

b. Evaluation and Performance Measurement

i. CDC Evaluation and Performance Measurement Strategy In collaboration with the CDC, the awardee will design an evaluation and performance measurement plan https://www.cdc.gov/hiv/group/gender/pregnantwomen/organizations.html http://www.grants.gov/ http://www.grants.gov/ http://www.cdc.gov/ncbddd/disabilityandhealth/disability-inclusion.html

In collaboration with the CDC, the awardee will design an evaluation and performance measurement plan that includes both outcome and process measures. The awardee, as well as CDC, may suggest additional performance measures to those listed below. As part of the development of an evaluation and measurement plan, CDC and awardee will develop a core set of indicators. Specific evaluation questions and performance measures, time-frame, data sources, and program targets for the required activities will be developed in collaboration between the awardee and CDC.

Evaluation and progress reports

Prepare a written assessment of the accomplishments, challenges and opportunities including a description of the problems encountered, lessons learned, and potential improvements.

The following process measures for activities should be considered:

1) Update CDC’s Framework for the Elimination of Mother-to-Child HIV Transmission.

Indicators of success: completion of at least two information-gathering meetings with key stakeholders regarding potential changes to the Framework by January 1, 2018 and submission of a final report to CDC regarding information gathered regarding potential updates to the Framework by March 15, 2018.

2) Develop and disseminate strategies for jurisdictions to describe progress in elimination of perinatal HIV infection using measures identified in updated EMCT Framework.

Indicators of success: document a baseline number of state and local health department grantees with published goals of elimination of perinatal HIV infection and their progress toward elimination by November 1, 2018; creation of a compendium of strategies for jurisdictions to describe their progress toward elimination by March 1, 2019; distribute compendium of strategies to all state health departments and CDC-funded city health departments by May 1, 2019; and reach out to state health departments without documented progress toward elimination to assess reasons for no specific goal of elimination by September 1, 2019.

3) Convene a stakeholder group representing a broad network of public health professionals and clinical care providers to implement the updated EMCT Framework.

Indicators of success: host a first annual meeting of the stakeholders group by December 31, 2018 and meetings at least annually thereafter; establish and staff 5-6 working groups based on the updated EMCT framework by February 1, 2019 and develop workgroup-specific action plans by June 1, 2019; host a work group meeting for developing and disseminating strategies to integrate care for HIV, mental health and substance use disorders by April 1, 2019.

4) Develop educational and best-practice-sharing networks of the perinatal HIV prevention workforce including clinical care providers and public health professionals.

Indicators of success: establish a broader stakeholder group network by July 1, 2019, conduct at least one educational event related to the action plans from the work groups for each clinical and public health audience by March 1, 2020 and at least annually thereafter.

The following outcome measures should also be considered and documented in an annual progress report:

1) Increase awareness among clinicians of the updated EMCT Framework

Indicator of success: documentation of the change in number of HIV care clinicians reporting knowledge of the updated framework annually after HIV-care-provider educational events.

2) Increase number of state and local health departments describing progress in elimination of perinatal HIV infections

Indicator of success: agreement by at least 25 health departments to publish their progress toward elimination of perinatal HIV transmission on the internet or in the literature by October 1, 2020; actual reports by at least 25 health departments about their progress toward elimination by October 1, 2021

3) Increase knowledge among health care providers about the interaction of HIV care of adults and prevention of perinatal HIV transmission

Indicator of success: documentation of increase in knowledge in pre- and post- educational event evaluations among at least 300 health care providers by June 1, 2021.

4) Maintain the gains (e.g., low number of infections) in prevention of perinatal HIV transmission.

Indicator of success: no increases in the annual national number of cases of diagnosed perinatal HIV nor in the rate of perinatal HIV transmission among infants born in the United States as documented in CDC HIV surveillance reports.

The awardee will monitor program performance throughout the project period. Program outcome and process data will be submitted to CDC annually.

CDC will collaborate with the awardee to develop a Data Management Plan (DMP) in the event that it is determined that data collection will be necessary as part of a working group’s action plan. For more information about CDC’s policy on the DMP, see http://www.cdc.gov/grants/additionalrequirements/index .html#ui-id-49

ii. Applicant Evaluation and Performance Measurement Plan Applicants must provide an evaluation and performance measurement plan that demonstrates how the awardee will fulfill the requirements described in the CDC Evaluation and Performance Measurement and Project Description sections of this FOA. At a minimum, the plan must describe:

How applicant will collect the performance measures, respond to the evaluation questions, and use evaluation findings for continuous program quality improvement.

How key program partners will participate in the evaluation and performance measurement planning processes.

Available data sources, feasibility of collecting appropriate evaluation and performance data, and other relevant data information (e.g., performance measures proposed by the applicant) Plans for updating the Data Management Plan (DMP), if applicable, for accuracy throughout the lifecycle of the project. The DMP should provide a description of the data that will be produced using these FOA funds; access to data; data standards ensuring released data have documentation describing methods of collection, what the data represent, and data limitations; and archival and long-term data preservation plans. For more information about CDC’s policy on the DMP, see https://www.cdc.gov/grants/additionalrequirements/ar-25.html.

Where the applicant chooses to, or is expected to, take on specific evaluation studies, they should be directed to:

Describe the type of evaluations (i.e., process, outcome, or both).

Describe key evaluation questions to be addressed by these evaluations.

Describe other information (e.g., measures, data sources).

Awardees will be required to submit a more detailed Evaluation and Performance Measurement plan, including a DMP, within the first 6 months of award, as described in the Reporting Section of this FOA.

c. Organizational Capacity of Awardees to Implement the Approach Applicants must have at least 10 years of experience coordinating and facilitating the work of large groups http://www.cdc.gov/grants/additionalrequirements/index.html#ui-id-49 http://www.cdc.gov/grants/additionalrequirements/index.html#ui-id-49 https://www.cdc.gov/grants/additionalrequirements/ar-25.html

Applicants must have at least 10 years of experience coordinating and facilitating the work of large groups of diverse stakeholders toward a common national public health goal related to HIV prevention and/or maternal and child health. Applicants must also have at least 10 years of experience with developing and delivering educational programs to health care providers on a national scale and show evidence of having changed the practice of public health and medical care for HIV prevention and/or maternal and child health.

Applicants should submit CVs/Resumes of the Principal Investigator and all key staff. Applicants must name the file ”CVs/Resumes.pdf” and upload it at www.grants.gov.

d. Work Plan A work plan is required for the first year and a ‘high-level’ plan for subsequent years of the project. A specific format is not required, as long as it is clear how the components of the work plan crosswalk to the strategies and activities, outcomes, evaluation and performance measures presented in the logic model and narrative section of the FOA. A sample work plan format is presented below to show how a traditional work plan aligns with the logic model and narrative. [In this format, the table would be completed for each project period outcome. If a particular activity leads to multiple outcomes, it should be described under each outcome measure.]

Project Period Outcome: Outcome Measure:

Strategies and Activities Project Measure Responsible Position/Party Completion date

1.

2.

3.

4.

5.

6.

e. CDC Monitoring and Accountability Approach Monitoring activities include routine and ongoing communication between CDC and awardees, site visits, and awardee reporting (including work plans, performance, and financial reporting). Consistent with applicable grants regulations and policies, CDC expects the following to be included in post-award monitoring for grants and cooperative agreements:

Tracking awardee progress in achieving the desired outcomes.

Ensuring the adequacy of awardee systems that underlie and generate data reports.

Creating an environment that fosters integrity in program performance and results.

Monitoring may also include the following activities deemed necessary to monitor the award:

Ensuring that work plans are feasible based on the budget and consistent with the intent of the award.

Ensuring that awardees are performing at a sufficient level to achieve outcomes within stated timeframes.

Working with awardees on adjusting the work plan based on achievement of outcomes, evaluation results and changing budgets.

Monitoring performance measures (both programmatic and financial) to assure satisfactory performance levels.

Monitoring and reporting activities that assist grants management staff (e.g., grants management officers and specialists, and project officers) in the identification, notification, and management of high-risk grantees.

f. CDC Program Support to Awardees (THIS SECTION APPLIES ONLY TO COOPERATIVE

AGREEMENTS)

In a cooperative agreement, CDC and the awardee share responsibility for successfully implementing the award and meeting identified outcomes. Thus, CDC staff members are substantially involved in the program activities, above and beyond grant monitoring. CDC activities for this program are as follows:

Provide consultation and technical assistance to awardee on all aspects of the implementation of the funding program, as well as all protocols, procedures, and instruments related to the plan, both directly and through CDC’s network of awardees and partners.

Work with awardee to address training, capacity building, and technical assistance needs that are crucial to the successful execution of the plan and that are not addressed by other funding sources.

Monitor awardee progress in implementing the program and consult with awardee via site visits, email, telephone, and review of progress reports to support implementation of the project.

Monitor awardee progress in developing and conducting monitoring and evaluation activities through consultation via site visits, email, telephone, and review of progress reports and other data reports to support progress, program improvement, and reductions in HIV incidence.

Facilitate necessary CDC and other clearances.

B. Award Information

1. Funding Instrument Type: Cooperative Agreement CDC's substantial involvement in this program appears in the CDC Program

Support to Awardees Section.

2. Award Mechanism: U65 Minority/Other Community-based HIV Prevention Project, Cooperative Agreements.

3. Fiscal Year: 2017

4. Approximate Total Fiscal Year Funding:

$400,000

5. Approximate Project Period Funding:

$2,000,000

This amount is subject to the availability of funds.

Estimated Total Funding: $2,000,000

6. Total Project Period Length:

5 year(s)

7. Expected Number of Awards:

8. Approximate Average Award:

$400,000 Per Budget Period

9. Award Ceiling: $400,000 Per Budget Period

This amount is subject to the availability of funds.

10. Award Floor: $300,000 Per Budget Period

11. Estimated Award Date: 09/29/2017

12. Budget Period Length: 12 month(s)

Throughout the project period, CDC will continue the award based on the availability of funds, the evidence of satisfactory progress by the awardee (as documented in required reports), and the determination that continued funding is in the best interest of the federal government. The total number of years for which federal support has been approved (project period) will be shown in the “Notice of Award.” This information does not constitute a commitment by the federal government to fund the entire period. The total project period comprises the initial competitive segment and any subsequent non-competitive continuation award(s).

13. Direct Assistance Direct Assistance (DA) is not available through this FOA.

C. Eligibility Information

1. Eligible Applicants Eligibility Category: State governments

County governments City or township governments Special district governments Independent school districts Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits without 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education For profit organizations other than small businesses Small businesses Others (see text field entitled "Additional Information on Eligibility" for clarification) Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"

Additional Eligibility Category:

2. Additional Information on Eligibility Domestic institutions or organizations are eligible to apply. Foreign institutions are not eligible to apply.

An individual is not eligible to apply for this cooperative agreement. Applicants must propose applications that are specific to one or more of the "Focus Areas of Programmatic Interest" (HIV/AIDS, Viral Hepatitis, STD or TB prevention). Applications that do not comply with this requirement will be determined non-responsive and will not be reviewed.

3. Justification for Less than Maximum Competition N/A

4. Cost Sharing or Matching Cost Sharing / Matching Requirement:

No

Cost sharing or matching funds is not required for this program. Although no statutory matching requirement for this FOA exists, leveraging other resources and related ongoing efforts to promote sustainability is strongly encouraged.

5. Maintenance of Effort Maintenance of effort is not required for this program.

D. Application and Submission Information

1. Required Registrations An organization must be registered at the three following locations before it can submit an application for funding at www.grants.gov.

a. Data Universal Numbering System:

All applicant organizations must obtain a Data Universal Numbering System (DUNS) number. A DUNS number is a unique nine-digit identification number provided by Dun & Bradstreet (D&B). It will be used as the Universal Identifier when applying for federal awards or cooperative agreements.

The applicant organization may request a DUNS number by telephone at 1-866-705-5711 (toll free) or internet at http:// fedgov.dnb. com/ webform/ displayHomePage.do. The DUNS number will be provided at no charge.

If funds are awarded to an applicant organization that includes sub-awardees, those sub-awardees must provide their DUNS numbers before accepting any funds.

b. System for Award Management (SAM):

The SAM is the primary registrant database for the federal government and the repository into which an entity must submit information required to conduct business as an awardee. All applicant organizations must register with SAM, and will be assigned a SAM number. All information relevant to the SAM number must be current at all times during which the applicant has an application under consideration for funding by CDC.

If an award is made, the SAM information must be maintained until a final financial report is submitted or the final payment is received, whichever is later. The SAM registration process can require 10 or more business days, and registration must be renewed annually. Additional information about registration procedures may be found at www.SAM.gov.

c. Grants.gov:

The first step in submitting an application online is registering your organization at www.grants.gov, the official HHS E-grant Web site. Registration information is located at the “Get Registered” option at www.grants.gov.

All applicant organizations must register at www.grants.gov. The one-time registration process usually takes not more than five days to complete. Applicants should start the registration process as early as possible.

Step System Requirements Duration Follow Up https://www.grants.gov/ http://fedgov.dnb.com/webform/displayHomePage.do https://www.sam.gov/portal/public/SAM/ https://grants.gov/ https://www.grants.gov/ https://www.grants.gov/ https://www.grants.gov/

1 Data Universal Number System

(DUNS)

1. Click on http:// fedgov.dnb.com/ webform

2. Select Begin

DUNS

search/request process

3. Select your country or territory and follow the instructions to obtain your DUNS 9-digit #

4. Request appropriate staff member(s) to obtain DUNS number, verify & update information under DUNS number

1-2 Business Days

To confirm that you have been issued a new DUNS number check online at (http:// fedgov.dnb.com/ webform) or call 1-866-705-5711Image Description:

2 System for Award Management

(SAM)

formerly Central Contractor Registration

(CCR)

1. Retrieve organizations DUNS number

2. Go to www.sam.gov and designate an E-Biz POC (note CCR username will not work in SAM and you will need to have an active SAM account before you can register on grants.gov)

3-5 Business Days but up to 2 weeks and must be renewed once a year

For SAM Customer Service Contact https://fsd.gov/ fsd-gov/ home.do Calls:

866-606-8220Image Description:

3 Grants.gov 1. Set up an individual account in Grants.gov using organization new DUNS number to become an authorized

Same day but can take 8 weeks to be fully registered and approved in the system

Register early! Log into grants.gov and check AOR status until it shows you have been approved http://fedgov.dnb.com/webform http://fedgov.dnb.com/webform http://fedgov.dnb.com/webform http://fedgov.dnb.com/webform http://fedgov.dnb.com/webform http://www.sam.gov https://fsd.gov/fsd-gov/home.do https://fsd.gov/fsd-gov/home.do organization representative

(AOR)

2. Once the account is set up the E-BIZ POC will be notified via email

3. Log into grants.gov using the password the E-BIZ POC received and create new password

4. This authorizes the AOR to submit applications on behalf of the organization

(note, applicants

MUST

obtain a

DUNS

number and SAM account before applying on grants.gov)

2. Request Application Package Applicants may access the application package at www.grants.gov.

3. Application Package Applicants must download the SF-424, Application for Federal Assistance, package associated with this funding opportunity at www.grants.gov. If Internet access is not available, or if the online forms cannot be accessed, applicants may call the CDC OGS staff at 770-488-2700Image Description: or e-mail OGS ogstims@cdc.gov for assistance. Persons with hearing loss may access CDC telecommunications at TTY 1-888-232-6348Image Description: .

4. Submission Dates and Times If the application is not submitted by the deadline published in the FOA, it will not be processed. Office of Grants Services (OGS) personnel will notify the applicant that their application did not meet the deadline.

The applicant must receive pre-approval to submit a paper application (see Other Submission Requirements section for additional details). If the applicant is authorized to submit a paper application, it must be received by the deadline provided by OGS.

a. Letter of Intent Deadline (must be emailed or postmarked by) Due Date for Letter of Intent: N/A

b. Application Deadline Due Date for Applications: 06/12/2017 , 11:59 p.m. U.S. Eastern Standard Time, at www.grants.gov. If Grants.gov is inoperable and cannot receive applications, and circumstances preclude advance notification of an extension, then applications must be submitted by the first business day on which grants.gov operations resume.

LOI is not requested or required as part of the application for this FOA.

Date for Information Conference Call

N/A https://www.grants.gov https://www.grants.gov mailto:ogstims@cdc.gov http://www.grants.gov

5. CDC Assurances and Certifications All applicants are required to sign and submit “Assurances and Certifications” documents indicated at http://wwwn.cdc.gov/ grantassurances/ (S(mj444mxct51lnrv1hljjjmaa)) /Homepage.aspx.

Applicants may follow either of the following processes:

Complete the applicable assurances and certifications with each application submission, name the file “Assurances and Certifications” and upload it as a PDF file with at www.grants.gov Complete the applicable assurances and certifications and submit them directly to CDC on an annual basis at http://wwwn.cdc.gov/ grantassurances/ (S(mj444mxct51lnrv1hljjjmaa))/ Homepage.aspx

Assurances and certifications submitted directly to CDC will be kept on file for one year and will apply to all applications submitted to CDC by the applicant within one year of the submission date.

Duplication of Efforts Applicants are responsible for reporting if this application will result in programmatic, budgetary, or commitment overlap with another application or award (i.e. grant, cooperative agreement, or contract) submitted to another funding source in the same fiscal year. Programmatic overlap occurs when (1) substantially the same project is proposed in more than one application or is submitted to two or more funding sources for review and funding consideration or (2) a specific objective and the project design for accomplishing the objective are the same or closely related in two or more applications or awards, regardless of the funding source. Budgetary overlap occurs when duplicate or equivalent budgetary items (e.g., equipment, salaries) are requested in an application but already are provided by another source.

Commitment overlap occurs when an individual’s time commitment exceeds 100 percent, whether or not salary support is requested in the application. Overlap, whether programmatic, budgetary, or commitment of an individual’s effort greater than 100 percent, is not permitted. Any overlap will be resolved by the CDC with the applicant and the PD/PI prior to award.

Report Submission: The applicant must upload the report in Grants.gov under “Other Attachment Forms.”

The document should be labeled: "Report on Programmatic, Budgetary, and Commitment Overlap.”

6. Content and Form of Application Submission Applicants are required to include all of the following documents with their application package at www.grants.gov.

7. Letter of Intent LOI is not requested or required as part of the application for this FOA.

8. Table of Contents (There is no page limit. The table of contents is not included in the project narrative page limit.): The applicant must provide, as a separate attachment, the “Table of Contents” for the entire submission package.

Provide a detailed table of contents for the entire submission package that includes all of the documents in the application and headings in the "Project Narrative" section. Name the file "Table of Contents" and upload it as a PDF file under "Other Attachment Forms" at www.grants.gov.

9. Project Abstract Summary (Maximum 1 page) A project abstract is included on the mandatory documents list and must be submitted at www.grants.gov.

The project abstract must be a self-contained, brief summary of the proposed project including the purpose and outcomes. This summary must not include any proprietary or confidential information. Applicants must enter the summary in the "Project Abstract Summary" text box at www.grants.gov.

http://wwwn.cdc.gov/grantassurances/(S(mj444mxct51lnrv1hljjjmaa))/Homepage.aspx https://www.grants.gov http://wwwn.cdc.gov/grantassurances/(S(mj444mxct51lnrv1hljjjmaa))/Homepage.aspx https://www.grants.gov https://www.grants.gov https://www.grants.gov enter the summary in the "Project Abstract Summary" text box at www.grants.gov.

10. Project Narrative (Unless specified in the "H. Other Information" section, maximum of 20 pages, single spaced, 12 point font, 1-inch margins, number all pages. This includes the work plan. Content beyond the specified page number will not be reviewed.)

Applicants must submit a Project Narrative with the application forms. Applicants must name this file “Project Narrative” and upload it at www.grants.gov. The Project Narrative must include all of the following headings (including subheadings): Background, Approach, Applicant Evaluation and Performance Measurement Plan, Organizational Capacity of Applicants to Implement the Approach, and Work Plan. The Project Narrative must be succinct, self-explanatory, and in the order outlined in this section. It must address outcomes and activities to be conducted over the entire project period as identified in the CDC Project Description section. Applicants should use the federal plain language guidelines and Clear Communication Index to respond to this Funding Opportunity Announcement. Note that awardees should also use these tools when creating public communication materials supported by this FOA. Failure to follow the guidance and format may negatively impact scoring of the application.

a. Background Applicants must provide a description of relevant background information that includes the context of the problem (See CDC Background).

b. Approach

i. Purpose Applicants must describe in 2-3 sentences specifically how their application will address the public health problem as described in the CDC Background section.

ii. Outcomes Applicants must clearly identify the outcomes they expect to achieve by the end of the project period, as identified in the logic model in the Approach section of the CDC Project Description. Outcomes are the results that the program intends to achieve and usually indicate the intended direction of change (e.g., increase, decrease).

iii. Strategies and Activities Applicants must provide a clear and concise description of the strategies and activities they will use to achieve the project period outcomes. Applicants must select existing evidence-based strategies that meet their needs, or describe in the Applicant Evaluation and Performance Measurement Plan how these strategies will be evaluated over the course of the project period. See the Strategies and Activities section of the CDC Project Description.

1. Collaborations Applicants must describe how they will collaborate with programs and organizations either internal or external to CDC. Applicants must address the Collaboration requirements as described in the CDC Project Description.

2. Target Populations and Health Disparities Applicants must describe the specific target population(s) in their jurisdiction and explain how such a target will achieve the goals of the award and/or alleviate health disparities. The applicants must also address how they will include specific populations that can benefit from the program that is described in the Approach section. Applicants must address the Target Populations and Health Disparities requirements as described in the CDC Project Description.

c. Applicant Evaluation and Performance Measurement Plan Applicants must provide an evaluation and performance measurement plan that demonstrates how the awardee will fulfill the requirements described in the CDC Evaluation and Performance Measurement and Project Description sections of this FOA. At a minimum, the plan must describe:

How applicant will collect the performance measures, respond to the evaluation questions, and use evaluation findings for continuous program quality improvement. The Paperwork Reduction Act of 1995 (PRA): Applicants are advised that any activities involving information collections (e.g., surveys, questionnaires, applications, audits, data requests, reporting, recordkeeping and disclosure requirements) from 10 or more individuals or non-Federal entities, including State and local governmental agencies, and funded or sponsored by the Federal Government are subject to review and approval by the Office of Management and Budget. For further information about CDC’s requirements under PRA see http://www.hhs.gov/ ocio/policy/collection/.

How key program partners will participate in the evaluation and performance measurement planning processes.

Available data sources, feasibility of collecting appropriate evaluation and performance data, data management plan (DMP), and other relevant data information (e.g., performance measures proposed by the applicant).

Where the applicant chooses to, or is expected to, take on specific evaluation studies, they should be directed to:

Describe the type of evaluations (i.e., process, outcome, or both).

Describe key evaluation questions to be addressed by these evaluations.

Describe other information (e.g., measures, data sources).

Awardees will be required to submit a more detailed Evaluation and Performance Measurement plan (including the DMP elements) within the first 6 months of award, as described in the Reporting Section of this FOA.

d. Organizational Capacity of Applicants to Implement the Approach Applicants must address the organizational capacity requirements as described in the CDC Project Description.

11. Work Plan (Included in the Project Narrative’s page limit) Applicants must prepare a work plan consistent with the CDC Project Description Work Plan section. The work plan integrates and delineates more specifically how the awardee plans to carry out achieving the project period outcomes, strategies and activities, evaluation and performance measurement.

This is included in the project narrative’s 20-page limit.

12. Budget Narrative Applicants must submit an itemized budget narrative. When developing the budget narrative, applicants must consider whether the proposed budget is reasonable and consistent with the purpose, outcomes, and program strategy outlined in the project narrative. The budget must include:

Salaries and wages Fringe benefits Consultant costs Equipment Supplies http://www.hhs.gov/ocio/policy/collection/

Travel Other categories Contractual costs Total Direct costs Total Indirect costs

Indirect costs could include the cost of collecting, managing, sharing and preserving data.

Indirect costs will not be reimbursed under grants to foreign organizations, international organizations, and foreign components of grants to domestic organizations (does not affect indirect cost reimbursement to the domestic entity for domestic activities).

For guidance on completing a detailed budget, see Budget Preparation Guidelines at:…