Attachment No. 3 - Questions & Answers.docx

This document contains questions and answers regarding Amendment #2 to solicitation FDA-RFP-1241927B. The solicitation seeks a contractor to conduct laboratory analysis to characterize and quantify chemical constituents of leachate from discarded electronic nicotine delivery system, or ENDS, components collected without direct interaction with users. Acceptable collection methods include gathering discarded components from public areas like streets, schools, and malls. While direct collection is preferred, an alternative approach of purchasing unused products and exposing them to simulated environmental conditions in a smoking machine would also be considered. The questions provide clarification on the agency's openness to alternative collection methods involving purchased rather than discarded products.