04_Atch_SOW_17R0011.pdf

Solicitation No. FA5209-17-R-0011 Attachment

STATEMENT OF WORK

FOR

DEPARTMENT OF THE ARMY

RESEARCH, DEVELOPMENT AND ENGINEERING COMMAND

INTERNATIONAL TECHNOLOGY CENTER-PACIFIC

(ITC-PAC)

DEVELOPMENT OF EPIDEMIC DECISION SUPPORT SYSTEMS BASED UPON

INFECTIVITY AND SEVERITY ESTIMATES OF INFECTIOUS DISEASES USING

THE FIRST FEW HUNDRED CASES METHODOLOGY

(Document No. W90GQZ-70660019)

1. DESCRIPTION OF SERVICE.

The overall objectives of the proposed research will be achieved as follows. The principal investigator (PI) will use new and existing data streams that provide information on severity, transmissibility [1] and forecast behavior [2] of infectious diseases to identify and recommend the appropriate response mechanisms (decision support) [2], based on existing pandemic response plans (such as the Australian Health Management Plan for Pandemic Influenza) where available [3]. The PI will use Dynamic Bayesian Networks to integrate all available information on epidemic behavior in order to provide robust recommendations on response options, including advice on uncertainty with respect to both future epidemic behavior and likely (absolute and relative) effectiveness of alternative response strategies. The decision support algorithm(s) will be developed, calibrated against and evaluated based on pandemic influenza in the Australian context, but the underlying methodology will be applicable to several other jurisdictions and diseases including Middle East Respiratory Syndrome (MERS)/Severe Acute Respiratory Syndrome (SARS), Ebola or an outbreak from bacterial infection. Extensions to these scenarios will be pursued once a satisfactory outcome for influenza management has been achieved.

Through the project, The PI will review recommendations in existing pandemic response plans.

The PI will work closely with the University of Adelaide (affiliated contract) to ensure the seamless integration of their First Few Hundred methodology-based estimates of epidemic severity and transmissibility into our decision support systems. The PI will provide support/advice to aid in the testing of a prototype in a table top exercise, and for IT professionals to finalize deployment of our algorithms as tools in relevant software environments.

The duration of this Research and Development is 12 months with a 12-month option.

1.2. DELIVERABLES.

1.2.1. First Deliverable (Basic Period) - Project Proposal.

Prior to commencement of work, the contractor shall submit ITC-PAC a Project Proposal which is to measure the progress of the Project, for ITC-PAC’s acceptance.

Project Proposal shall include, at a minimum, the following information:

Project title Investigators

- Name

- Position title

- Organization name

- Address

- Telephone number

- Fax number

- Email address

Concise summary Abstract Objectives Relevance to DoD Background Summary of project plan, expected project result and expected project benefit Project duration Budget details (equipment, labor, etc.)

References

1.2.2. Second Deliverable (Basic Period) – Interim Report.

The contractor shall submit an interim report detailing the progress of the completed segments of the project to ITC-PAC at the end of the 6-month stage after commencement of work.

Interim Report shall include, at a minimum, the following information:

Status of project plan.

Progress made in the first 6 months.

Projected progress to be made in the next 6 months.

1.2.3. Third Deliverables (Basic Period)

1.2.3.1. Final Report of Basic Period

The contractor shall submit the Final Report of Basic Period to ITC-PAC with all the results, problems and/or discoveries encountered during the project phases within 30 days after the Basic Period ends.

The Final Report of Basic Period shall include, at a minimum, the following information;

- Name

- Position title

- Organization name

- Address

- Telephone number

- Fax number

- Email address

Summary (or Abstract) of the Project Introduction (or Background) Experiment Result & Discussion Conclusion Acknowledgement Reference

1.2.3.2. Financial Report of Basic Period

Together with the Final Report of Basic Period, the contractor shall deliver the Financial Report of this Project to ITC-PAC.

The Financial Report of Basic Period shall include the cost spent for the Project in the following category:

Labor Cost, and Direct Cost (Materials, Publication & Report, Travel).

1.2.3.3 Software Application Version 0

Together with the Final Report and Financial Report of this Project for the Basic Period, the contractor shall deliver the initial version of their software application implementing the project developed decision support algorithm(s) to ITC-PAC.

The delivered application will be in the form of standalone software suitable for being ported by a third party into the Biosurveillance Ecosystem (BSVE) environment that performs the stated analysis/computations on epidemiological data sets. This application will incorporate epidemic forecasting into the decision support algorithm, test the decision support algorithm in an exercise, prepare the decision support algorithm for infectious disease management for professional IT development, and support professional software developers and write journal articles.

1.2.4. Fourth Deliverables (Option 1 Period) – Project Proposal

Before the Option 1 Period starts, the contractor shall submit ITC-PAC a Project Proposal for Option 1 Period which is to measure the progress of the Project, for ITC-PAC’s acceptance.

Project Proposal shall include, at a minimum, the following information:

- Name

- Position title

- Organization name

- Address

- Telephone number

- Fax number

- Email address

Concise summary Abstract Objectives Relevance to DoD Background Summary of project plan, expected project result and expected project benefit Project duration Budget details (equipment, labor, etc.)

References

1.2.5. Fifth Deliverable (Option 1 Period) – Interim Report

The contractor shall submit an interim report detailing the progress of the completed segments of the project to ITC-PAC at the end of the 6-month stage after commencement of Option 1 Period.

Interim Report shall include, at a minimum, the following information:

Status of project plan.

Progress made in the first 6 months.

Projected progress to be made in the next 6 months.

1.2.6. Sixth Deliverables (Option 1 Period)

1.2.6.1. Final Report

The contractor shall submit the Final Report to ITC-PAC with all the results, problems and/or discoveries encountered during the project phases within 30 days after the performance period ends.

The Final Report shall include, at a minimum, the following information;

- Name

- Position title

- Organization name

- Address

- Telephone number

- Fax number

- Email address

Summary (or Abstract) of the Project Introduction (or Background) Experiment Result & Discussion Conclusion Acknowledgement Reference

1.2.6.2. Financial Report

Together with the Final Report, the contractor shall deliver the Financial Report of this Project to

ITC-PAC.

The Financial Report shall include the cost spent for the Project in the following category:

Labor Cost, and Direct Cost (Materials, Publication & Report, Travel).

1.2.6.3. Software Application Version 1

Together with the Final Report and Financial Report of this Project for the Option 1 Period, the contractor shall deliver the final version of their standalone software application implementing the project developed decision support algorithm(s) to ITC-PAC.

The delivered application will be suitable for being ported by a third party into the BSVE environment that performs the stated analysis/computations on epidemiological data sets. This application will incorporate epidemic forecasting into the decision support algorithm, test the decision support algorithm in an exercise, prepare the decision support algorithm for infectious disease management for professional IT development, and support professional software developers and write journal articles.

1.3. PAYMENTS.

1.3.1. First Payment (Basic Period).

After ITC-PAC’s acceptance of a Project Proposal mentioned above (First Deliverable), the contractor shall submit the first invoice to ITC-PAC. The first payment will be made upon ITC- PAC’s certification of the invoice.

1.3.2. Second Payment (Basic Period).

After ITC-PAC’s acceptance of an interim report mentioned above (Second Deliverable), the contractor shall submit the second invoice to ITC-PAC. The second payment will be made upon ITC-PAC’s certification of the invoice.

1.3.3. Third Payment (Basic Period).

After ITC-PAC’s acceptance of the Third Deliverables mentioned above (Third Deliverable), the contractor shall submit the third invoice to ITC-PAC. The third payment will be made upon ITC-PAC’s certification of the invoice.

1.3.4. Fourth Payment (Option 1 Period).

After ITC-PAC’s acceptance of the Project Proposal for Option 1 Period mentioned above (Fourth Deliverable), the contractor shall submit the fourth invoice to ITC-PAC. The fourth payment will be made upon ITC-PAC’s certification of the invoice.

1.3.5. Fifth Payment (Option 1 Period).

After ITC-PAC’s acceptance of an interim report mentioned above (Fifth Deliverable), the contractor shall submit the fifth invoice to ITC-PAC. The fifth payment will be made upon ITC- PAC’s certification of the invoice.

1.3.6. Sixth Payment (Option 1 Period).

After ITC-PAC’s acceptance of the Sixth Deliverables mentioned above (Sixth Deliverable), the contractor shall submit the sixth invoice to ITC-PAC. The sixth payment will be made upon ITC-PAC’s certification of the invoice.

2. GOVERNMENT FURNISHED PROPERTY. No US government furnished property shall be provided nor used in this project.

3. GENERAL INFORMATION.

3.1. Contractor Employees. Personnel shall meet or exceed the following requirement:

3.1.1. Contractor shall not hire employees of the United States Government and/or employees otherwise under contract for service to the United States Government if employing such persons would create a conflict of interest, or appearance of a conflict of interest as determined by the contractor. Contractor shall not employ any person who is an employee of DoD, unless such person seeks and receives approval according to DODR 5500.7, Standards of Conduct.