DJA-24-AHDQ-N-0007 - Liquid Chromatography Mass Spectrometry (LCMS).docx

REQUEST FOR INFORMATION

Bureau of Alcohol, Tobacco, Firearms and Explosives Forensic Science Laboratory – Washington (FSL-W)

Liquid Chromatograph Mass Spectrometer (LCMS) with Diode Array Detector (DAD) and Components

1. RFI Purpose:

This Request for Information (RFI) as identified in the Federal Acquisition Regulation (FAR) 15.201 (c)(7) is issued solely for market research and planning purposes. It does not constitute an Invitation for Bids, Request for Proposal, or Request for Quotes. ATF is not seeking or accepting unsolicited proposals.

Responses to this notice are not offers and cannot be accepted by the Government to form a binding contract. Those who respond to this RFI should not anticipate feedback concerning their submission. All submissions will become the property of the Government and will not be returned. Proprietary information, if any, must be clearly marked on all material(s) submitted. All information received marked Proprietary will be handled in accordance with 41 USC §§ 2101-2107. Responding to the RFI is completely voluntary and will not enhance or adversely affect responses to any resulting future solicitation. There is no competitive advantage gained by any of the respondents to this RFI. Additionally, the Government will not provide reimbursement for any information that may be submitted in response to this RFI. Respondents are solely responsible for all expenses associated with responding to this RFI. No promise of future business with the Government will result from responding to this RFI.

The Government is not required to respond to any questions submitted in response to this RFI. At the Government’s discretion it may schedule demonstrations with vendors as time permits following the close of the RFI response period. Additionally, Industry is encouraged to advise the Government what other information it needs to better understand its requirements, to reduce the risk contingency built into pricing, and to reduce barriers to competition.

2. Requirement:

The objective of this RFI is to obtain submissions that can provide the ATF with a LCMS-DAD with Jet Stream ability. ATF is seeking responses for market research purposes only. Interested parties shall provide any RFI feedback, relevant technical capabilities, relevant past performance, and market research pricing. The vendor should demonstrate the following:

· LC/MSD must include the following technical specifications:

· Have a LC /MSD base system.

· Must have an orthogonal Jet Stream Electro Spray ionization (ESI) source.

· Upgrade kit for the Jet Stream

· Must have an Atmospheric pressure chemical ionization (APCI) source spray chamber with corona discharge needle, nebulizer, APCI vaporizer and calibration kit.

· Includes the Open lab CDS software, PC workstation and printer.

· Have an operational mass range (m/z) of 2-3000 m/z.

· The detection system must be composed of a High Energy Dynode detector (HED) design.

· The HED contains (1) dynode that is orthogonal to the ion beam and neutrals.

· The instrument shall support the following ionization sources: ESI Multimode source (simultaneous ESI and APCI), APCI source.

· The ion sources shall have an orthogonal orientation and be constructed of inert materials and auto-aligning.

· Must have ESI positive 1 picogram (pg) of reserpine injected on column, quantifying the m/z 609 ion Signal-to-noise ratio, RMS (root mean square) >300:1.

· SIM sensitivity for APCI positive is 1 pg of reserpine injected on column, quantifying the m/z 609 ion Signal-to-noise ratio, RMS >100:1.

· Must be able to time program the following: SIM ion selection, Drying gas flow, Scan functions, Nebulizer pressure, Fragmentor voltage, Drying gas temperature, External CAN valves, Capillary voltage (Positive), MS diverter valve, Capillary voltage (Negative)

· Vacuum system must have one mechanical pump for the mass spectrometer and the turbo molecular pump must be air-cooled.

· Source temperatures must be electronically controlled through the software.

· The nebulizer shall use nitrogen gas to promote ionization.

· The same ion source shall operate with HPLC and UHPLC systems.

· Pump must include the following technical specifications:

· Low-Dispersion tubing

· Bundled Poroshell 120 EC-C18 2.1x100mm, 1.9uM column.

· Must have a low gradient delay volume of the pump = 350 µL

· Flow precision must be ≤0.07% RSD or ≤0.01 min SD.

· Composition precision must be ≤0.15% RSD or ≤0.02 min SD.

· Hydraulic system must have dual pistons in series.

· Must deliver a flow rate of up to 5mL/min.

· Must have operating range up to 130 MPa (1300 bar) up to 2 ml/min, 80 MPa (800 bar) at 5 ml/min.

· Must have a pH range 1.0 — 12.5.

· Must include active seal wash, tool kit solvent cabinet and bottles.

· Injector must include the following technical requirements:

· Must include a vial sampler for up to 1300 bar, 40uL metering device and the 20uL sample loop with integrated needle flush port.

· Vail sampler must have a temperature control of up to 80 °C and a sample thermostat for temperatures from 2 °C to 40°C all within one module.

· Vail sampler must be able to hold at least 132 (2 mL) vials or 36 (6 mL) vials.

· Vail sampler must have a minum sample volume of 1 μL from 5 μL sample in 100 μL microvial, or 1 μL from 10 μL sample in 300 μL microvial.

· Must have an integrated sample cooler installed inside of the module.

· Must have a cooling accuracy of 2 °C to 6 °C at a setpoint of 4 °C.

· Must allow an injection volume range of 0.1 to 500µL or 1500 µL by seat loop extension.

· Injection cycle time of 18 seconds.

· Multi column thermostat (MCT) must include the following technical requirements.

· up to eight columns with 10 cm length and a temperature range from 20°C below ambient to 110°C all 8 columns.

· Must have at least two independent temperature zones.

· Must have a temperature range at high flow rates: 10°C below ambient to 100°C at up to 2.5 ml/min flow of pure Water and 10°C below ambient to 80°C at up to 5 ml/min flow of pure Water.

· Temperature accuracy must be ± 0.8 °C or ± 0.5 °C with calibration.

· Valves must easily exchange by user-exchangeable.

· 8-column selection at the same pressure range as of the pump must be available

· The pump flow will be controlled by firmware and reduced before a valve will be switched.

· Columns of up to 30cm length must be supported.

· Must be a self-contained module with solvent resistant material used in all areas which may have contact with the mobile phase.

· The module must enable pre column heating and post column cooling.

· Must have a temperature range from 20°C below ambient to 110°C.

· Must have temperature precision of +/- 0.05 ° C.

· DAD must include the following technical requirements.

· DAD software compatible with CDS

· Must have programmable slit widths of 1, 2, 4, 8 nm.

· Must have Radio Frequency Identification Tags for UV lamp.

· Must have Radio Frequency Identification Tags for flow cells.

· Upgrade possibility to HDR-DAD for higher Linearity (15x wider UV linear range vs. Infinity DAD, 30x wider UV-linear range vs 1200 Series DAD)

· Must be able to simultaneous acquire up to 8 compounds with specific wavelengths.

· Must have Max-Light cartridge cells with optofluidic waveguides to improve light transmission.

· 100% efficiency without sacrificing resolution caused by cell dispersions effects.

· Must have a maximum sampling rate of 240 Hz Full spectral data.

· Signal drift must be equal or smaller 0.5 x 10-3 AU/h after adequate warm up.

· Must be a 1024-element diode array.

· The temperature operating range of instrument must be from 4°C to 40°C.

· Must have OpenLab CDS instrument connection for 1 LC, GC, analog and digital converter, 3D ultraviolet/DAD connection and MS detector connection.

· InfinityLab Waste can GL45, 6L + GL45 4 ports cap, includes one 6-liter Lab Waste can and one Stay Safe, Cap GL45 4 ports for waste.

· InfinityLab Charcoal filter 58g w. time strip for InfinityLab Stay Safe Cap

· Must include method and application consulting for on-site consulting for up to four (4) people.

· All physical items supplied with the buy must be brand new and be certified to manufacturer’s OEM specifications.

· Instrument, computer, printer and all the components will be covered under a one (1) year manufacture warranty (not to include consumables).

Contractor Qualifications.

· The Contractor must be able to demonstrate that they can meet the described requirements in section 2.

· The Contractor must be registered and up to date in the System for Award Management (SAM).

3. Small Business Considerations:

A decision regarding the small business strategy for this requirement, if it results in an acquisition, has not been made. That decision will be made, in part, based upon the responses to this RFI. It is therefore important that companies provide the requested information on its business size and socio-economic status. Small businesses are advised that FAR 52.219-14, Limitations on Subcontracting, would apply wherein at least 50 percent of the work must be performed by the small business prime contractor alone.

4. Response Guidelines:

Information provided in response to this RFI must be submitted to Brian Palmer (brian.palmer@atf.gov), Contract Specialist in the form of an electronic document using portable document format (PDF) or Microsoft Word. The page limit for all responses is not to exceed ten (10) single-sided, 12-font size, 8½ x 11-inch pages, excluding any current product description information.

Respondents should include the following information:

· Organization name, mailing address, e-mail address, telephone and fax numbers, website address (if available) and the name, telephone number, and e-mail address of a point of contact having the authority and knowledge to clarify responses with Government representatives.

· Company Information: Business Size and Socio-Economic Status – Provide your company’s business size (small/large) and include all your firm’s NAICS codes in the RFI response. In addition, indicate your business’ socio-economic status (e.g., HUBZone, Service Disable Veteran Owned Small business, Women-Owned small business, Small Disadvantaged Business, 8(a) Program

· Contract Vehicles – The RFI response shall include all current contract vehicles (e.g., GWACs, GSA Multiple Award Schedules).