D1 PD.pdf

Purchase Description

Name of Item or Project Title:

Purchase of ten (10) linear drives of each axis (x,y) set for the BioRaptr automated liquid dispensing system for NCATS.

Statement of Need and Purpose:

Purchase of ten (10) linear drives of each axis (x,y) set for the BioRaptr automated liquid dispensing system for the Division of Preclinical Innovation (DPI) within the National Center for

Advancing Translational Sciences (NCATS) in order to replace linear drives on NCATS existing equipment used in the labs with Tox21 and HRB automated systems

Background Information and Objective:

The National Institutes of Health (NIH) is the nation’s leading medical research agency and the primary Federal agency whose mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability, conducting, supporting and making medical discoveries that improve people’s health and save lives.

The National Center for Advancing Translational Sciences (NCATS) is a part of the National

Institutes of Health (NIH), which mission it is to catalyze the generation of innovative methods and technologies that will enhance the development, testing and implementation of diagnostics and therapeutics across a wide range of human diseases and conditions.

The Division of Preclinical Innovation (DPI) plans, conducts and uses both internal and contract resources to advance collaborative research projects across the preclinical phases of the translational science spectrum.

The BioRaptr dispenses fluid volumes from 1ul to 25ul into microplates dependent on a dispensing spreadsheet created by the user. The dispensing uses stationary syringes located at the top of the equipment while the microplate is positioned below on movable x, y and z axes.

The Beckman Coulter BioRaptr automated liquid dispensing system is DPI’s facility’s primary means of automated liquid dispensing for the microliter ranges. The equipment is used in all

NCATS labs including the TOX21 and HRB automated systems. DPI’s facility has purchased about 18 of these that are maintained by onsite engineering staff. Most maintenance involves the replacement and calibration of the dispensing valves. On infrequent occasions a liquid leak can develop above the plate positioning linear drives causing non repairable damage to that component.

Thus, considering the number of BioRaptrs that DPI’s currently maintains, infrequent occasions that could lead to the replacement of the BioRaptr linear drives can refer to 2-4 times per year, which requires the acquisition of the spare parts for expedite repair to bring the equipment to operational conditions without jeopardizing the research performed in the labs.

Generic Name of Product:

Linear drives of each axis (x,y) set for a Beckman Coulter BioRaptr.

Purchase Description

Purchase Description:

Ten (10) linear drives of each axis (x,y) set fully compatible with Beckman Coulter BioRaptr.

The salient characteristics of the linear drives of each axis (x,y) set shall include:

• Fully compatible with Beckman Coulter BioRaptr and interchangeable with OEM parts.

• Handling and Shipping, FOB Destination.

Quantity:

Ten (10) sets

Delivery Date:

Delivery is required within thirty (30) days months after receipt of the order (ARO). Delivery shall be made to the below address with FOB Destination.

National Center for Advancing Translational Sciences (NCATS)

9800 Medical Center Drive

Rockville, MD 20850