D. Purchase Description.pdf
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- Solicitation number
- 75N95020Q00131
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This document contains a purchase description for a federal contract opportunity. The requisition is to purchase a Sirius Automation 6-Axis Arm Linear Rail System with accessories and service for the Compound Management group within the Division of Pre-Clinical Innovation at the National Center for Advancing Translational Sciences within the National Institutes of Health. The robotic arm system is needed to transfer various racks, plates, and vials between instrumentation platforms to automate sample purification and processing and increase efficiency. Key requirements for the system include a precision 6-axis arm and controller with grippers designed for automated transfer of specified rack and plate types between designated equipment as required by workflow. The opportunity was solicited under solicitation number 75N95020Q00131 for the acquisition of the Sirius Automation 6-Axis Arm Linear Rail System by the Department of Health and Human Services National Institutes of Health National Institute on Drug Abuse.
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| D. Sirius Noncomp CSS.pdf |
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Purchase Description Statement of Need and Purpose:
Background Information and Objective:
Generic Name of Product:
Purchase Description:
Salient Characteristics:
Quantity:
Delivery Date:
Period of Performance:
Option(s):
9.0.0.2.20101008.1.734229
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| Include a general narrative of the need of the requirement and the desired results.: This requisition is to purchase a Sirius Automation 6-Axis Arm Linear Rail System with accessories and service for the Compound Management group within the Division of Pre-Clinical Innovation (DPI) at NCATS. |
| Include a brief history of the requirement, the importance of the requirement, and the overall program objectives.: The National Center for Advancing Translational Sciences (NCATS) within the National Institutes of Health (NIH) has a mission to catalyze the generation of innovative methods and technologies that will enhance the development, testing and implementation of diagnostics and therapeutics across a wide range of human diseases and conditions. To this end, DPI maintains a library of >400,000 compounds, which is used in high-throughput biological screening assays focusing on various protein targets and disease states. The Analytical Chemistry group within the DPI maintains a state-of-the-art laboratory whose mission is to support chemistry research throughout the Center. With our primary focus on small molecule analysis and purification, the laboratory maintains a wide variety of instrumentation facilitating medicinal, synthetic, and analytical chemistry efforts focused on early-stage chemical development. A core responsibility of the group is to isolate and purify internally synthesized compound with material in the range of milligrams to grams for addition to the NCATS library. |
The development of a centralized sample purification and processing platform in conjunction with the Sample Management and Resource Tracking (SMART) laboratory information management system (LIMS), continues to be utilized at DPI for sample submission, compound purification, compound processing, sample registration, compound inventory, sample tracking, data retrieval, and data management. Functionality is added to improve efficiency and productivity based on expanding and changing scientific needs. As part of the ASPIRE program, the Analytical Chemistry group has begun the creation of an automated purification platform. Early stages of this endeavor look to optimize current purification processes and connect various islands of automation in an efficient manner. The end goal is a fully autonomous system, which can be integrated into an automated synthesis platform. In order the facilitate this, we need a robotic arm system that can transfer various racks, plates, and vials between the Sirius OmniTasker sample processing platform, the Sirius MicroTasker NMR sample preparation platform, and several other instrument systems. Additionally, the robotic arm must be operated by a scheduling software that is compatible with the Sirius Automation software to ensure proper operability and performance. Application of the Sirius Automation 6-Axis Arm Linear Rail System to advance automated sample purification and processing will increase efficiency and productivity.
| Specify the generic name of the component or system, e.g., freezer, microscope, cell sorter, etc.: 6-axis robotic arm on a linear rail |
| Specify 1) trade name; 2) product’s brand name; 3) manufacturer's name; 4) model, type, catalog, and/or part number(s.): Sirius Automation 6-Axis Arm Linear Rail System |
| Specify the significant, essential physical, functional, performance, or material element(s) (the distinguishing characteristic) of a product, system, component, or service required. Specify the functions that a system or component must perform to meet the Government’s objectives. Include required levels of performance, features or characteristics of the system or component that are essential to meet the government’s objectives. Specify the Government’s minimum acceptable standards.: The unique features of the Sirius Automation 6-Axis Arm Linear Rail System are: |
1. Precision 6-Axis Arm with controller module and grippers designed to complete the automated transfer of racks (4x6 Rack for 1 Dram vials, 96-position Matrix Rack, LCMS Plate, & Deep Well Plate plus disposable type NMR vessels) as required by designated workflow between Sirius OmniTasker® to Sirius MicroTasker®, Sirius FlashScan2D® Rack Reader and MagriTek benchtop NMR with the ability to interface with the Agilent PlateLoc plate sealer and benchtop synthesizer.
2. Robust extrusion-based reinforced frames with mounting plates bolted on your existing lab bench to house the 6-Axis Arm, plus proprietary 14’ stepper motor driven X axis ‘AccuSpan®’ bridge member sustaining weight and accuracy of positioning of same using HDHP lead screw mechanism, with <0.05mm accuracy and <0.20mm precision.
3. “Light Curtain” safety switches on two faces/planes to halt the move the 6-Axis Arm/StepperDriver if interrupted (controlled access by Operator or external robot excepted).
4. Sirius ‘Conduct®’ Custom Orchestration Software running concurrently on the OmniTasker® or MicroTasker® PC Controller to coordinate the tasks between Sirius OmniTasker® to Sirius MicroTasker®, and to control the FlashScan2D® Rack Reader, the Agilent PlateLoc plate sealer and the MagriTek Benchtop NMR which will all be ‘slaved’ to the Orchestration Program.
5. Configured to accept access from co-operative ‘BioSero” Robot Arm and requires specialty bench to accommodate height restrictions.
6. Expansion positions may be added as required.
7. Complete with Installation, Comprehensive Integration and User Training.
| Specify quantity. : One (1) each per product listed in salient characteristics |
| Specify desired delivery date after receipt of order (30-60 days.): 120 days after receipt of the award |
| Specify period of performance for software license, warranty, or maintenance agreements.: One (1) twelve (12) month period of warranty coverage and support to begin after installation of system is complete. |
| Specify if options for additional quantities or options to extend the term of the contract for service agreements.: N/A |
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