D. CSS_75N95023Q00603_Attachment 1_Purchase Description_final.pdf

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

Title: Miltenyi Biotec gentleMACS™ Octo Dissociator with Heaters or Equal

1. Statement of Need and Purpose:

The purpose of this acquisition is to procure two (2) Miltenyi Biotec gentleMACS™ Octo Dissociator with Heaters, which will be used by the National Institute of Neurological Disorders and Stroke (NINDS), Laboratory of Viral Immunology and Intravital Imaging (VIIIS) for mission critical experiments.

2. Background Information and Objective:

The National Institutes of Health (NIH), a part of the U.S. Department of Health and Human Services, is the nation’s medical research agency — making important discoveries that improve health and save lives. The NINDS, which is 1 of 27 NIH Institutes and Centers (ICs), mission is to seek fundamental knowledge about the brain and nervous system and to use that knowledge to reduce the burden of neurological disease for all people.

The NINDS VIIIS investigates how the innate and adaptive immune systems participate in different neurological disorders such as meningitis, encephalitis, cerebral malaria, and traumatic brain injury (TBI). This laboratory currently has a dissociator that is used to dissociate cells from tissues of interest for single cell RNAseq experiments. This current instrument only holds eight (8) samples, but typically the NINDS researchers and scientists need to process up to twenty (20) samples per experiment. Therefore, NINDS has a need for a quantity of two (2) new Miltenyi Biotec gentleMACS™ Octo Dissociator with Heaters or equal that will allow its ongoing research to continue without disruption.

3. Generic Name of Product:

Cell Dissociator

4. Purchase Description:

Trade name: gentleMACS™ Dissociator with Heating Units Brand name/description: gentleMACS™ Dissociator with Heating Units Manufacturer: Miltenyi Biotec, Inc.

Part number: 130-096-427

5. Salient characteristics:

The significant, essential physical, functional, performance, or material element(s) that are the Government’s minimum acceptable standards for an equivalent gentleMACS™

Dissociator with Heating Units manufactured by Miltenyi Biotec, Inc., to meet the government’s objective are as follows.

Each cell dissociator shall consist of the minimum requirements as follows:

• It must be a benchtop instrument (minimum dimensions 465×285 mm) with a touchscreen for the automated dissociation or homogenization of up to eight (8) samples.

• It must include up to eight (8) Heating Units.

• It must have a Power Cord, power socket, on/off switch, 2D code reader, USB port, CAN port and RS232 port.

• It must have C Tubes or M Tubes compatibility for obtaining single-cell suspensions or thorough homogenates for easilbility and reproducibly.

• Minimum torque of 200 rpm up to 4000 rpm.

• Shall be warranted, and the Contractor shall warrant that all electrical equipment will be free from defects for a period of at least one (1) year from the date of installation, inspection by the Government, and acceptance. The Contractor shall further warrant that all components will be free from defects for a period of at least one (1) year from the date of installation, inspection by the Government and acceptance. Warranty service shall include trouble-shooting capabilities based on complete knowledge of the entire system. A rapid response (within one business day) to service requests is required. The Contractor shall demonstrate that it is capable of providing this level and speed of service. Warranty shall not include routine or periodic maintenance services.

6. Quantity: Two (2)

7. Delivery Date: 30-60 days after receipt of order (ARO) addressed to:

Building 10 / Room 5N240C 10 Center Drive Bethesda, MD 20892-1444

8. Period of Performance: Not applicable.

9. Option(s): Not applicable.

10. Other Requirements

Warranty - The Contractor shall warrant that all electrical equipment will be free from defects for a period of at least one (1) year from the date of installation, inspection by the Government, and acceptance. The Contractor shall further warrant that all components will be free from defects for a period of at least one (1) year from the date of installation, inspection by the Government and acceptance. Warranty service shall include trouble-shooting capabilities based on complete knowledge of the entire system. A rapid response (within one business day) to service requests is required. The Contractor shall demonstrate that it is capable of providing this level and speed of service. Warranty shall not include routine or periodic maintenance services.