D-Attachment PURCHASE DESCRIPTION.pdf

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Purified influenza virus antigens from eggs
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75P00125Q00072
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This document is a Purchase Description for procuring influenza virus antigens for scientific research. The Structural Informatics Unit requires high-purity influenza viruses for vaccine purification, immunogenicity studies, and electron microscopic image processing. The purchase includes six specific influenza virus strains: A/PR/8/34, X-31 A/AICHI/68, A/Victoria/3/75, A/HongKong/8/68, and B/Lee, each supplied as 1ml liquid purified antigens at 2mg/ml concentration, to be stored at -70°C. The total order consists of 60 antigen units, along with dry ice and freight, with a delivery requirement of 30 days after receipt of order (ARO).

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Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

1. Statement of Need and Purpose:

2. Background Information and Objective: The laboratory (Structural Informatics Unit) designs and studies the structure and epitopes display of influenza vaccine nanoparticles by immunogenicity, biochemical, and electron microscopic techniques. As such the purified influenza virus will be used to carry out research in vaccine purification, immunogenicity and image processing of electron microscopic images used to study vaccine particle structures assembled from purified influenza virus. High purity levels of influenza viruses are needed to make vaccines for structural and animal studies.

3. Generic Name of Product: Antigens for universal influenza vaccine studies

4. Purchase Description:

Influenza A/PR/8/34, Purified 1ml Liquid Purified Antigen at 2mg/ml, Store at -70C

Lot:4XP231114 Manufactured Date: 111/14/2023 Titer: EID50=8.4 Additional Titer: HA=4096

(QTY=26)

Influenza X-31 A/AICHI/68, Purified 1ml Liquid Purified Antigen at 2mg/ml, Store at -70C Lot:4XX210323 Titer: HA=65536 Additional Titer: EID50=10.0/ml (QTY=10)

Influenza A/Victoria/3/75, Purified 1ml Liquid Purified Antigen at 2mg/ml, Store at -70C

Lot:4XV181116 (QTY=4)

Influenza A/HongKong/8/68, Purified 1ml Liquid Purified Antigen at 2mg/ml, Store at -70C Lot:4XH210305 (QTY=10)

Influenza B/Lee, Purified 1ml Liquid Purified Antigen at 2mg/ml, Store at -70C Lot:4XL180322

Manufactured Date: 3/22/2018 Titer: EID50=8.7 Additional Titer: HA=16384 (QTY=10)

Dry Ice (QTY=1)

Freight Flat Amount (QTY=1)

5. Salient characteristics

6. Quantity: See purchase description above for quantities

7. Delivery Date: 30 days ARO

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