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COMBINED SYNOPSIS / SOLICITATION

75N95024Q00479

TITLE: Brand Name or Equal: Olink Target 48 Mouse Cytokine Panel and Detection System

(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice.

This announcement constitutes the only solicitation; quotations are being requested and a written solicitation will not be issued.

(ii) The solicitation number is 75N95024Q00479 and the solicitation is issued as a request for quotation (RFQ). This acquisition is for a commercial item and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13 - Simplified Acquisition Procedures and FAR Part 12 - Acquisition of Commercial Items, and is not expected to exceed the simplified acquisition threshold.

(iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2024-05-06 effective May 22, 2024.

(iv) The associated NAICS code is 334516 and the Small Business size standard is 1,000 employees. This requirement is full and open and no set aside restrictions are applicable.

DESCRIPTION

(v) The National Institute on Aging (NIA) at the National Institutes of Health (NIH) leads a broad scientific effort to understand the nature of aging and to extend the healthy, active years of life, and is the primary Federal agency supporting and conducting Alzheimer's disease and related dementias research. The purpose of the acquisition is to purchase Brand Name or Equal Olink Target 48 Mouse Cytokine kits and the Signature Q100 system, along with the required installation and training needed to perform these assays. We are seeking to measure levels of multiple cytokines in serum samples collected longitudinally from mice. Due to the limited volume of blood that can be collected from live mice and the number of other tests that have been or are being performed in these samples, only 5uL of serum is available to perform this analysis.

The research requiring this brand-name or equal products is being conducted as part of the Study of Longitudinal Aging in Mice (SLAM), a comprehensive assessment of normative aging in mice. As part of this work, we are performing a comprehensive assessment of longitudinally collected serum samples to identify age related biomarkers and circulating factors associated with senescence. Circulating cytokines are important biomarkers of aging and senescence, but are not detected in the mass spec based proteomics and metabolomics approaches that have been used previously on these samples.

CSS 75N95024Q00479

The NIA requires the below or brand-name equal products:

Part No.

Part Name Description Qty

93400 Olink® Target 48 Mouse Cytokine

Olink® Target 48 panel for rapid analysis of protein concentration of 40+ mouse cytokines in 1uL of sample.

93007 Olink® 48.48 IFC for Protein Expression

Olink-branded Integrated Fluidic Circuit (IFC) for performing proteomic analysis in 48.48 format (48 proteins, 48 samples).

96056 Olink® Signature Q100 Certified Installation

On-site installation by a Standard BioTools Field Service Engineer.

96050 Olink® Signature Q100 IQOQ Service

Installation qualification and operational qualification (IQOQ) for the Signature Q100. provides documented evidence and verification that the instrument has been installed and is operating according to manufacture specifications during a wet test.

BD0030 Olink® Signature Olink Target/Flex/Focus Training Package

Includes one training kit, virtual training, and one-year software license. Includes one-year warranty, interface plate for

48.48 format, power cord, pooled plamsa sample, Integrated Fluidic Circuit (IFC), and Cytokine reagent kit.

Salient Characteristics: The salient characteristics are as follows:

• Simultaneously measures up to 96 proteins using less than 1μL of serum, plasma, or a wide range of other types of biological sample matrix.

• Benchtop system

• Designed and optimized for readout of Target 96, Target 48, and Focus panels

• Has integrated Fluidic Circuit (IFC) controller for IFC priming and loading

• Includes software that directly opens and analyzes run data files comprehensively.

• Has a built-in system control computer.

• Has warranty.

• Small footprint – less that 12 in by 24 in.

• Achieves a high level of multiplexing while maintaining exceptional data quality

(vi) Delivery and Installation: The anticipated delivery date is within 30 days after award.

Delivery is to be made to the below city and state, FOB destination. The exact address will be noted on the purchase order.

Baltimore, MD 21224

Installation and training are anticipated to occur within 30 days after delivery.

EVALUATION AND AWARD

(vii) The anticipated award date is August 15, 2024.

(viii) The Government plans to make one firm, fixed-price award resulting from this solicitation. The resulting award will be made to the responsible quoter whose quote conforming to the solicitation will be most advantageous to the Government, price and other factors considered, using comparative evaluations. The following factors shall be used to evaluate quotes:

1. Technical Capability: the ability to provide the brand-name or equal products, and the quoter’s delivery and installation/training timelines.

2. Past Performance. The Government may use any source of available past performance information (see FAR 13.106-2(b)(3)).

3. Price.

SUBMISSION INSTRUCTIONS

(ix) All responses to this RFQ must be received by 11:00am Eastern Time on Thursday, August 8, 2024 and must reference the solicitation number cited above. Responses must be submitted via email to Kimberly Espinosa at kimberly.espinosa@nih.gov.

(x) This is an RFQ. This request does not commit the Government to pay any costs incurred in the preparation of the submission of this quotation or to contract for supplies or service. Supplies are of domestic origin unless otherwise indicated by quoter. Any representations and/or certifications attached to this RFQ must be completed by the quoter.

(xi) Responses to this RFQ must include clear and convincing evidence of the quoter’s capability of fulfilling the requirement as it relates to the technical evaluation criteria. Responses may exceed capability or performance characteristics of the solicitation's requirements. The Government reserves the right, but is not required, to award to a response that exceeds capability or performance characteristics of the solicitation's requirements if it provides a benefit to the Government.

(xii) Responses must include the Unique Entity Identifier (UEI), the Taxpayer Identification Number (TIN), the certification of business size, and the completed certification in FAR Provision 52.225-6 (attached). Responses must also include a completed copy of the FAR Provision 52.212-3, Offeror Representations and Certifications—Commercial Products and Commercial Services (Nov 2023), with its quote. If the respondent has completed FAR clause 52.212-3 at www.sam.gov, then the respondent does not need to provide a completed copy with its quote.

CSS 75N95024Q00479

mailto:kimberly.espinosa@nih.gov file://nidawfsprd01.nida.nih.gov/SHARED/OM/CMB/RED/NINDS_Section/Contracts/1_Awarded/75N95024P00095_ThorLabs,%20Inc/1_Neg_Acq_Presol-Award/D-Solicitation/www.sam.gov

(xiii) Responses must also include a quotation in U.S. dollars that includes:

1. The total price,

2. Individual prices for each item,

3. Prompt payment discount terms,

4. Product or catalog number(s),

5. Product description,

6. The dates by which the quoter can deliver the products and perform the installation and training, and

7. Any other information or factors that may be considered in the award decision. Such factors may include: special features required for effective program performance; trade-in considerations; warranty considerations; maintenance availability; and environmental and energy efficiency considerations.

(xiv) For information about this RFQ, contact Kimberly Espinosa, Contracting Officer, at 301-827-

3546 or kimberly.espinosa@nih.gov.

(xv) All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency.

TERMS AND CONDITIONS, PROVISIONS, AND REPRESENTATIONS

(xvi) The provision at FAR 52.252-1, Solicitation Provisions Incorporated by Reference (Feb

1998). This solicitation incorporates one or more solicitation provisions by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. The offeror is cautioned that the listed provisions may include blocks that must be completed by the offeror and submitted with its quotation or offer. In lieu of submitting the full text of those provisions, the offeror may identify the provision by paragraph identifier and provide the appropriate information with its quotation or offer. Also, the full text of a solicitation provision may be accessed electronically at www.acquisition.gov.

The following provisions apply to this acquisition and are incorporated by reference:

1. FAR Provision 52.204-7, System for Award Management (Oct 2018)

2. FAR Provision 52.204-16, Commercial and Government Entity Code Reporting (Aug 2020)

3. FAR Provision 52.212-3, Offeror Representations and Certifications—Commercial Products and Commercial Services (May 2024)

(xvii) The clause at FAR 52.252-2, Clauses Incorporated by Reference (Feb 1998). This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. Also, the full text of a clause may be accessed electronically at www.acquisition.gov.

In addition to the clauses checked in FAR 52.212-5 (attached), the following clauses also apply to this acquisition and are incorporated by reference:

1. FAR Clause 52.204-13, System for Award Management Maintenance (Oct 2018)

2. FAR Clause 52.204-18, Commercial and Government Entity Code Maintenance (Aug 2020)

3. FAR Clause 52.212-4, Contract Terms and Conditions – Commercial Products and

Commercial Services (Nov 2023)

4. HHSAR Clause 352.222-70, Contractor Cooperation in Equal Employment Opportunity

Investigations (December 18, 2015)

(xviii) The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement.

(xix) One or more of the items under this acquisition is subject to the World Trade Organization

Government Procurement Agreement and Free Trade Agreements

ATTACHMENTS

(xx) The following terms, provisions, and clauses are incorporated and attached in full text:

1. FAR Provision 52.212-1, Instructions to Offerors – Commercial Products and Commercial Services (Sep 2023) (Tailored)

2. FAR Provision 52.225-6, Trade Agreements Certificate (Feb 2021)

3. FAR Clause 52.212-5, Contract Terms and Conditions Required to Implement Statutes or

Executive Orders–Commercial Products and Commercial Services (May 2024)

4. Addendum to FAR Clause 52.212-4, Contract Terms and Conditions – Commercial

Products and Commercial Services

5. NIH Electronic Invoice Submission Instructions with IPP (March 21, 2023)