Combined Synopsis Solicitation 36C24126Q0517.docx

Attachment 1: Combined Synopsis-Solicitation for Commercial Products and Commercial Services RFQ: 36C24126Q0517 Test Kits and Reagents

Description This is a combined synopsis/solicitation seeking domestic commercial products and commercial services prepared in accordance with the format Revolutionary FAR Overhaul (RFO) in Federal Acquisition Regulation (FAR) subpart 12.202, “Streamlined Procedures for Evaluation and Solicitation for Commercial Products and Commercial Services,” as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are being requested, and a written solicitation document will not be issued.

This solicitation is issued as an RFQ. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2026-01.

This solicitation has no set-aside.

The associated North American Industrial Classification System (NAICS) code for this procurement is 325413, with a small business size standard of 1,250 employees.

The FSC/PSC is 6550.

The Network Contracting Office (NCO) 1- New England is seeking to Test kits and reagents as a Firm-Fixed Price contract.

If you have any questions or concerns regarding this solicitation should be forwarded in writing via email to the Point of Contact listed below:

Tara Dossiema Tara.Dossiema@va.gov

All interested companies shall provide quotations for the following:

(STATEMENT OF WORK)

1.0 Minimum Salient Requirements

The kits and reagents must be able to facilitate a variety of genomic research tasks related to single-cell analysis. Kits and reagents must function in the intending systems, must not void any warranties, and include:

1.1). Single-Cell RNA Sequencing (scRNA-seq),

· Profiling gene expression at the single-cell level to understand cellular heterogeneity.

This research evaluates how individual cells in tissue express genes differently, which is crucial for understanding the developmental biology, disease mechanisms, and responses to treatments.

1.2). Single-Cell ATAC Sequencing (scATAC-seq)

· Investigating chromatin accessibility and regulatory elements.

This technique enables research into chromatin structure and accessibility change in different cell types and under various conditions. It’s useful for studying gene regulation, transcription factor binding sites, and epigenetic modifications.

1.3). Single-Cell Multiome (RNA + ATAC)

· Simultaneous profiling of gene expression and chromatin accessibility in single cells.

This is an advanced application where both RNA sequencing (scRNA-seq) and chromatin accessibility (scATAC-seq) are performed in parallel on the same cells. It allows for the study of gene expression regulation and the interaction between transcription and chromatin accessibility within individual cells.

1.4). Single-Cell DNA Sequencing (scDNA-seq),

· Profiling DNA content, mutations, and genomic alterations at the single-cell level.

This is especially important in research where cells may have unique mutations or genetic alterations. It can also be used for studying genetic diversity within a population of cells in development or disease.

1.5). Spatial Transcriptomics

· Mapping gene expression in tissue sections while preserving spatial context.

The spatial transcriptomics technology allows the profiling of gene expression in intact tissue sections with spatial context (i.e. gene expression can be mapped across a tissue sample without losing information about where specific genes are being expressed in relation to the tissue architecture). This is critical for understanding tissue development, organ function, and disease progression.

1.6). Cellular Barcoding (Cell Type Identification)

· Identifying cell types or tracking cells across experiments.

By incorporating unique molecular barcodes, researchers can tag and track individual cells across different conditions or over time. This is useful for studying dynamic processes like differentiation, migration, and response to therapy.

1.7). Single-Cell Epigenomics

· Investigating DNA methylation and histone modifications at the single-cell level.

This application provides insights into epigenetic changes that regulate gene expression.

1.8). Gene Expression Profiling of Rare Cell Populations

· Analyzing rare or low-abundance cell types.

Single-cell RNA sequencing can help identify and profile rare cell populations that are difficult to detect using traditional bulk methods. This is especially useful in studying stem cells, progenitor cells, or rare disease-associated cell types.

1.9). Saliant Features necessary for postmortem brain genomics work:

· Droplet-based microfluidics technology to enable highly efficient partitioning and barcoding of individual cells, allowing for accurate and scalable single-cell RNA-seq, immune profiling, and other multi-omic analyses.

· High Sensitivity and Resolution: Kits must be validated for their ability to achieve exceptional depth and coverage of gene expression, even with very low input RNA, making them ideal for high-resolution single-cell analysis.

· Comprehensive Applications: Kits must support a broad range of applications, including single-cell RNA sequencing, cell surface protein analysis, immune profiling, and spatial transcriptomics. These applications are critical for the success of current research.

· Proven Performance and Validation: Extensive track record of peer-reviewed literature demonstrating the successful application of the kits in a wide variety of research fields. This body of evidence assures reliability and reproducibility of experimental efforts.

2.0 Deliverables and Price Cost Schedule

(END OF STATEMENT OF WORK)

The purchase order/contract period of performance will be for one year.

Place of Performance/Place of Delivery

VA CT Healthcare System West Haven Medical Center 950 Campbell Ave West Haven, CT

(START OF CLAUSES AND PROVISIONS)

The full text of FAR provisions or clauses may be accessed electronically at https://www.acquisition.gov/far-overhaul.

The following solicitation provisions and clauses apply to this acquisition:

1. FAR 52.212-1, Instructions to Offerors-Commercial Products and Commercial Services (SEP 2023) (DEVIATION OCT 2025) All quoters shall submit the following: Price, Technical, and Past Performance All quotes shall be sent to the Contracting Officer, Tara Dossiema, Tara.Dossiema@va.gov.

Award will be based upon a comparative evaluation of quotes in accordance with the Simplified Acquisition Procedures of RFO FAR 12. Comparative evaluation is the side by side pairwise comparison of quotes based on factors resulting in a Contracting Officer decision for the quote most favorable to the Government.

2. www.sam.gov registration is required to be complete at time of submission of response. Offerors must complete annual representations and certifications electronically via the System for Award Management (SAM) website located at https://sam.gov/ .

3. FAR 52.212-4, Contract Terms and Conditions-Commercial Products and Commercial Services (NOV 2023) (DEVIATION OCT 2025)

4. FAR 52.252-1, Solicitation Provisions Incorporated by Reference (FEB 1998) - This solicitation incorporates one or more solicitation provisions by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. The offeror is cautioned that the listed provisions may include blocks that must be completed by the offeror and submitted with its quotation or offer. In lieu of submitting the full text of those provisions, the offeror may identify the provision by paragraph identifier and provide the appropriate information with its quotation or offer. Also, the full text of a solicitation provision may be accessed electronically at this/these address(es): https://www.acquisition.gov/far-overhaul/far-part-deviation-guide/far-overhaul-part-52#FAR_52_252_1 (FAR) and http://www.va.gov/oal/library/vaar/index.asp (VAAR)

5. ADDENDUM to FAR 52.212-2 EVALUATION—COMMERCIAL PRODUCTS AND COMMERCIAL SERVICES (DEVIATION AUG 2025)

(a) The following factors shall be used to evaluate quotations:

(1) Technical or Quality: The offeror’s quote shall be evaluated to determine if the contractor has the experience and capabilities to provide quality services in a timely and efficient manner.

a. Contractor shall demonstrate their corporate experience and approach to meet all requirements stated in the Statement of Work.

b. If you are planning to sub-contract some or all of this work, please provide the name and address(s) of all subcontractor(s) (if applicable) and a description of their planned subcontracting effort.

(2) Price:

a. Complete line items on Page 2 of this combined synopsis/solicitation, which will be completed by the offeror.

(b) Evaluation Approach. The Government will evaluate quotations using the comparative evaluation process outlined in FAR 12, where quotations will be compared to one another to determine which provides the best benefit to the Government. The Government reserves the right to consider a quotation other than the lowest price that provides additional benefit(s). Quotations may exceed minimum requirements of the solicitation. The Government reserves the right to select a quotation that provides benefit to the Government that exceeds the minimum requirements of the solicitation but is not required to do so. Each response must meet the minimum requirements of the solicitation. The Government is not requesting or accepting alternate quotations. The evaluation will consider the following:

(1) Technical or Quality: The quotation will be evaluated to the extent to which it can meet and/or exceed the Government’s requirements as outlined in the solicitation and based on the information requested in the instructions to quoters section of the solicitation.

(2) Price: The Government will evaluate the price by adding the total of all line-item prices. The Total Evaluated Price will be that sum.

6. FAR 52.203-11, Certification and Disclosure Regarding Payments to Influence Certain Federal Transactions. (SEP 2024)

7. FAR 52.203-18, Prohibition on Contracting with Entities that Require Certain Internal Confidentiality Agreements or Statements-Representation. (JAN 2017)

8. FAR 52.204-7, System for Award Management—Registration (NOV 2024) (DEVIATION NOV 2025)

9. FAR 52.252-2, Clauses Incorporated by Reference (FEB 1998) - This contract incorporates one or more clauses by reference, with eh same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. Also, the full text of a clause may be accessed electronically at this/these address(es): https://www.acquisition.gov/far-overhaul (RFO) and http://www.va.gov/oal/library/vaar/index.asp (VAAR)

10. FAR 52.203-6, ALT I. Restrictions on Subcontractor Sales to the Government.(NOV 2021

11. FAR 52.203-17, Contractor Employee Whistleblower Rights. (NOV 2023)

12. FAR 52.203-19, Prohibition on Requiring Certain Internal Confidentiality Agreements or Statements. (JAN 2017)

13. FAR 52.204-9, Personal Identity Verification of Contractor Personnel (JAN 2011)

14. FAR 52.204-13, System for Award Management-Maintenance (OCT 2018) (DEVIATION NOV 2025)

15. FAR 52.209-6, Protecting the Government's Interest When Subcontracting With Contractors Debarred, Suspended, Proposed for Debarment, or Voluntarily Excluded. (JAN 2025) (DEVIATION NOV 2025)

16. FAR 52.209-10, Prohibition on Contracting With Inverted Domestic Corporations. (NOV 2015) (DEVIATION NOV 2025)

17. FAR 52.219-6, Notice of Total Small Business Set-Aside. (NOV 2020) (DEVIATION NOV 2025)

18. FAR 52.219-8, Utilization of Small Business Concerns. (JAN 2025) (DEVIATION NOV 2025)

19. FAR 52.219-14, Limitations on Subcontracting. (OCT 2022) (DEVIATION NOV 2025)

20. FAR 52.222-3, Convict Labor. (JUN 2003) (DEVIATION NOV 2025)

21. FAR 52.222-19, Child Labor-Cooperation with Authorities and Remedies. (JAN 2025) (DEVIATION NOV 2025)

22. FAR 52.222-35, Equal Opportunity for Veterans. (JUN 2020) (DEVIATION NOV 2025)

23. FAR 52.222-36, Equal Opportunity for Workers with Disabilities. (JUN 2020) (DEVIATION NOV 2025)

24. FAR 52.222-37, Employment Reports on Veterans. (JUN 2020) (DEVIATION NOV 2025)

25. FAR 52.222-40, Notification of Employee Rights Under the National Labor Relations Act. (DEC 2010) (DEVIATION NOV 2025)

26. FAR 52.222-41, Service Contract Labor Standards. (AUG 2018) (DEVIATION NOV 2025)

27. FAR 52.222-42, Statement of Equivalent Rates for Federal Hires. (MAY 2014)

28. FAR 52.222-43, Fair Labor Standards Act and Service Contract Labor Standards-Price Adjustment (Multiple Year and Option Contracts). (AUG 2018) (DEVIATION NOV 2025)

29. FAR 52.222-50, Combating Trafficking in Persons. (NOV 2021) (DEVIATION NOV 2025)

30. FAR 52.22-90, Addressing DEI Discrimination by Federal Contractors (DEVIATION)

31. FAR 52.222-54, Employment Eligibility Verification. (JAN 2025) (DEVIATION NOV 2025)

32. FAR 52.222-62, Paid Sick Leave Under Executive Order 13706. (JAN 2022) (DEVIATION NOV 2025)

33. FAR 52.223-23, Sustainable Products. (MAY 2024) (DEVIATION NOV 2025)

34. FAR 52.224-3, Privacy Training. (JAN 2017)

35. FAR 52.226-8, Encouraging Contractor Policies to Ban Text Messaging While Driving. (MAY 2024)

36. FAR 52.232-33, Payment by Electronic Funds Transfer-System for Award Management. (OCT 2018)

37. FAR 52.232-40, Providing Accelerated Payments to Small Business Subcontractors. (MAR 2023)

38. FAR 52.233-3, Protest after Award. (AUG 1996) (DEVIATION NOV 2025)

39. FAR 52.233-4, Applicable Law for Breach of Contract Claim. (OCT 2004) (DEVIATION NOV 2025)

40. FAR 52.240-91, Security Prohibitions and Exclusions. (DEVIATION NOV 2025)

41. FAR 52.244-6, Subcontracts for Commercial Products and Commercial Services. (JAN 2025) (DEVIATION OCT 2025)

42. FAR 52.217-5, Evaluation of Options (JULY 1990) (DEVIATION NOV 2025)

43. FAR 52.217-8, Option to Extend Services (NOV 1999)

44. FAR 52.219-1, Small Business Program Representations. (FEB 2024) (DEVIATION NOV 2025)

45. FAR 52.233-2, Service of Protest (SEP 2006) (DEVIATION NOV 2025)

46. FAR 52.252-5, Authorized Deviations in Provisions (NOV 2020) - (a) The use in this solicitation of any Federal Acquisition Regulation (48 CFR Chapter 1) provision with an authorized deviation is indicated by the addition of "(DEVIATION)" after the date of the provision.

(b) The use in this solicitation of any VA Acquisition Regulation (VAAR) and 48 CFR Chapter 8 provision with an authorized deviation is indicated by the addition of "(DEVIATION)" after the name of the regulation.

47. FAR 52.219-28, Postaward Small Business Program Rerepresentation (JAN 2025)

48. FAR 52.222-55, Minimum Wages for Contractor Workers Under Executive Order 14026

(JAN 2022) (DEVIATION NOV 2025)

49. FAR 52.223-5, Pollution Prevention and Right-to-Know Information (MAY 2024)

50. FAR 52.224-1, Privacy Act Notification (APR 1984)

51. FAR 52.224-2, Privacy Act (APR 1984)

52. FAR 52.229-3, Federal, State, and Local Taxes (FEB 2013) (DEVIATION SEP 2025)

53. FAR 52.237-2, Protection of Government Buildings, Equipment, and Vegetation (APR 1984)

54. FAR 52.252-6, Authorized Deviations in Clauses (NOV 2020) - (a) The use in this solicitation or contract of any Federal Acquisition Regulation (48 CFR Chapter 1) clause with an authorized deviation is indicated by the addition of "(DEVIATION)" after the date of the clause.

(b) The use in this solicitation or contract of any VA Acquisition Regulation (VAAR) and 48 CFR Chapter 8 clause with an authorized deviation is indicated by the addition of "(DEVIATION)" after the name of the regulation.

55. VAAR 852.233-70, Protest Content/Alternative Dispute Resolution (SEP 2018)

56. VAAR 852.233-71, Alternate Protest Procedure (SEP 2018)

57. VAAR 852.252-70, Solicitation Provisions or Clauses Incorporated by Reference (JAN 2008)

58. VAAR 852.201-70, Contracting Officer’s Representative (DEC 2022)

59. VAAR 852.204-70, Personal Identity Verification of Contractor Personnel (MAY 2020)

60. VAAR 852.203-70, Commercial Advertising (MAY 2018)

61. VAAR 852.204-70, Personal Identity Verification of Contractor Personnel (MAY 2020)

62. VAAR 852.232-72, Electronic Submission of Payment Requests (NOV 2018)

63. VAAR 852.242-71, Administrative Contracting Officer (OCT 2020)

(END OF CLAUSES AND PROVISIONS)

To facilitate the award process, all quotes must include a statement regarding the terms and conditions herein as follows:

"The terms and conditions in the solicitation are acceptable to be included in the award document without modification, deletion, or addition."

Quoters shall list exception(s) and rationale for the exception(s), if any.

Submission of your response shall be received not later than 06/04/2026 at 9:00 AM EST. and email sent to Tara.Dossiema@va.gov. Any questions shall be received no later than 05/27/2026 at 9:00 AM EST.

Late submissions shall be treated in accordance with the solicitation provision at FAR 52.212-1(f). Not Accepted.

Any questions or concerns regarding this solicitation should be forwarded in writing via e-mail to the Point of Contact listed: Tara Dossiema Tara.Dossiema@va.gov