Combined Synopisis-Solicitation 75N94025Q00178.pdf

COMBINED SYNOPSIS / SOLICITATION

WORKFORM

(1) Action Code: Combined Synopsis/Solicitation

(2) Date: 09/17/2025

(3) Year: 2025

(4) Contracting Office Zip Code: 20892

(5) Product Classification Code: 6640 - Laboratory Equipment and Supplies

(6) Contracting Office Address:

NIH/NICHD/OA Acquisitions Services Branch (ASB) 6710-B Rockledge Drive Bethesda, MD 20817

(7) Subject/Title: Flow Cytometer for NIDDK

(8) Solicitation Number: 75N94025Q00178

(9) Closing Response Date: 09/21/2025 1700 ED

(10) Contact Point: Jacob Balenson, Contracting Officer

(11) Contract Award Number: TBD

(12) Contract Award Dollar Amount: TBD

(13) Contract Line Item Number(s): TBD

(14) Contract Award Date: TBD

(15) Contractor Name: TBD

(16) Background: The mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is to conduct and support medical research and research training and to disseminate science-based information on diabetes and other endocrine and metabolic diseases; digestive diseases, nutritional disorders, and obesity; and kidney, urologic, and hematologic diseases, to improve people’s health and quality of life. The NIDDK Intramural Research Program (IRP) conducts biomedical research and training related to diabetes mellitus; endocrine, bone, and metabolic diseases; digestive diseases, including liver diseases and nutritional disorders; and kidney, urologic, and hematologic diseases. Intramural research is conducted in the Institute's laboratories and clinical facilities in Bethesda, Maryland and in Phoenix, Arizona.

There are currently 17 Laboratories and Branches (i.e. 17 departments with different focus areas) in the NIDDK IRP. Most if not all these areas of research, either occasionally or on an ongoing basis, require advanced light microscopy methods to qualitatively complement other assays, or as the basis of a quantitative assay. A flow cytometer is a crucial instrument for immunology and studies related with human diseases. Our current flow cytometer was purchased in 2018 and is limited to roughly 10-14 color panels and now constrains the lab’s ability to dissect rare immune and parenchymal cell states in kidney, spleen, and tumor digests or to analyze irreplaceable patient samples. Modern immunology increasingly demands 40 plus parameters per cell to integrate flow data with single cell RNA seq, ATAC seq, and spatial transcriptomic pipelines already active in the lab. We need a new flow cytometer instrument that will shorten instrument queues, and serve as an open resource for neighboring groups that express interest, also broadening training opportunities for fellows across the institute. Without a new flow cytometer instrument, current and future research will be negatively affected because it will rely on an outdated instrument.

Description of the Requirement: We require a flow cytometer instrument that is designed for high-speed, high-parameter analysis of cells, offering both spectral and conventional flow cytometry capabilities. We require it to leverage acoustic focusing technology for precise cell alignment, and enable faster sample acquisition and clog-resistant fluidics. This is important to our lab research as it results in quicker, more accurate, and reliable data for researchers, particularly in fields like immunology and immuno-oncology. Review Attachment 1 - Statement of Need 75N94025Q00178, Section 4.0 ORDER REQUIREMENTS for all specifications.

a. This is a combined synopsis/solicitation for commercial products or commercial services prepared in accordance with part 12. This announcement constitutes the only solicitation. Offers are being requested and a separate written solicitation will not be issued.

b. This solicitation uses a brand name or equal purchase description in accordance with FAR Companion FC11.204.

c. The solicitation number is 75N94025Q00178 and the solicitation is issued as a request for quote

(RFQ).

d. The provisions and clauses incorporated in this solicitation document are those in effect through Federal Acquisition Circular 2025-05 effective 08/07/2025. The acquisition is being conducted in accordance with the procedures of FAR Part 12, and FAR Part 13.

e. The associated NAICS code is 334516 - Analytical Laboratory Instrument Manufacturing and the small business size standard in number of employees is 1,000. This is a full and open solicitation and is not set-aside.

f. Period of Performance: The Government anticipates delivery by 90 Days After Receipt of Order (ARO). Delivery Location: Kidney Disease Branch - NIDDK Immunoregulation Section Building 10, Room 10S224 10 CENTER DR BETHESDA MD 20892

g. Evaluation: The award will be made based on best value. Quotes will be evaluated based on the following factors: Cost/Price, Past Performance, Delivery Terms, and Technical Capability to meet the requirements outlined in the Statement of Need. Quotes must contain sufficient information for the Government to assess its level of confidence in the offeror based on the factors listed.

h. Responses should include a completed copy of FAR 52.212-3 Offeror Representations and Certifications—Commercial Products and Commercial Services [(DEVIATION FEB 2025)].

i. FAR 52.212-4, Contract Terms and Conditions – Commercial Items, applies to this acquisition.

Note: NIH Invoice and Payment Provisions are added as an addendum to this clause. Review Attachment 2 - NIH Invoice and Payment Provisions.

j. FAR 52.212-5 Contract Terms and Conditions Required To Implement Statutes or Executive Orders—Commercial Products and Commercial Services [(DEVIATION FEB 2025)], applies to this acquisition and is attached in full text. Review Attachment 3 - FAR 52.212-5 (JAN 2025)

[(DEVIATION FEB 2025)] 75N94025Q00178.

k. Additional Applicable Clauses:

52.203-11 Certification and Disclosure Regarding Payments to Influence Certain Federal Transactions 52.203-18 Prohibition on Contracting with Entities that Require Certain Internal Confidentiality Agreements or Statements-Representation FAR 52.204-24 Representation Regarding Certain Telecommunications and Video Surveillance Services or Equipment FAR 52.204-26 Covered Telecommunications Equipment or Services-Representation FAR 52.204-7 System for Award Management.

FAR 52.204-13 System for Award Management Maintenance HHSAR 352.232-71 Electronic submission of payment requests

(17)

Responses to this notice shall contain sufficient information to establish the interested parties capabilities for fulfilling the requirement. All respondents must have an active registration in the System for Award Management (SAM) www.sam.gov. All responses to this notice shall be submitted electronically by 5:00 PM ED, on 9/21/2025 to jacob.balenson@nih.gov and shall include solicitation number 75N94025Q00178 in the subject line.

Primary Point of Contact: Jacob Balenson, Contracting Officer, Email: jacob.balenson@nih.gov l.

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