CK19-1905 NOFO Final.pdf

Centers for Disease Control

National Center for Emerging and Zoonotic Infectious Diseases

CDC National Infection Control Strengthening . .

CDC-RFA-CK19-1905

Application Due Date: 08/05/2019

CDC National Infection Control Strengthening . .

CDC-RFA-CK19-1905

TABLE OF CONTENTS

Part I. Overview Information A. Federal Agency Name B. Funding Opportunity Title C. Announcement Type D. Agency Funding Opportunity Number E. Assistance Listings (CFDA) Number F. Dates G. Executive Summary

Part II. Full Text A. Funding Opportunity Description B. Award Information C. Eligibility Information D. Application and Submission Information E. Review and Selection Process F. Award Administration Information G. Agency Contacts H. Other Information I. Glossary

Part I. Overview Information Applicants must go to the synopsis page of this announcement at www.grants.gov and click on the "Send Me Change Notifications Emails" link to ensure they receive notifications of any changes to CDC-RFA-CK19-1905. Applicants also must provide an e-mail address to www.grants.gov to receive notifications of changes.

A. Federal Agency Name:

Centers for Disease Control and Prevention (CDC) / Agency for Toxic Substances and Disease Registry (ATSDR) B. Notice of Funding Opportunity (NOFO) Title:

CDC National Infection Control Strengthening . .

C. Announcement Type: New - Type 1 This announcement is only for non-research activities supported by CDC. If research is proposed, the application will not be considered. For this purpose, research is defined at https ://www.gpo.gov/fdsys/pkg/CFR-2007-title42-vol1/pdf/CFR-2007-title42-vol1-sec52-2.pdf.

Guidance on how CDC interprets the definition of research in the context of public health can be found at https://www.hhs.gov/ohrp/regulations-and-policy/regulations/45-cfr-46/index.html (See section 45 CFR 46.102(d)).

U38 – Cooperative Agreements to develop or improve facets of public health information in cooperation with eligible applicants National Infection Control Strengthening

D. Agency Notice of Funding Opportunity Number:

CDC-RFA-CK19-1905

E. Assistance Listings (CFDA) Number:

93.825 F. Dates:

1. Due Date for Letter of Intent (LOI): N/A

2. Due Date for Applications: 08/05/2019, 11:59 p.m. U.S. Eastern

Standard Time, at www.grants.gov.

3. Date for Informational Conference Call:

G. Executive Summary:

1. Summary Paragraph:

The National Ebola Training and Education Center (NETEC) that was established in 2016 has provided regional capabilities to care for patients with highly infectious hemorrhagic fever virus infections. With a track record of each of the three hospitals having safely delivered that care, the NETEC members’ facilities represent a clinical resource with unique experience and staffing that can now be used to extend that capacity to additional aspects of safe healthcare. By tailoring lessons learned to support smaller, less resourced community facilities, systematizing strategies for efficient, cost-effective organizational and structural adjustments to facilitate infection control, and identifying optimal processes to make clinical procedures safer, and improve PPE use and design, the original NETEC investment can yield benefits to a much larger array of facilities and improve the readiness of the US healthcare system to address https://www.grants.gov https://www.grants.gov https://www.gpo.gov/fdsys/pkg/CFR-2007-title42-vol1/pdf/CFR-2007-title42-vol1-sec52-2.pdf https://www.gpo.gov/fdsys/pkg/CFR-2007-title42-vol1/pdf/CFR-2007-title42-vol1-sec52-2.pdf https://www.hhs.gov/ohrp/regulations-and-policy/regulations/45-cfr-46/index.html https://www.grants.gov numerous epidemic threats. Throughout the three-year period of performance, each of the three facilities will work in collaboration with CDC experts in one of the following areas: in improving infection control at small and rural healthcare facilities, evaluating failure modes and human factors associated with IPC, and refining existing facilities and strategies into safe isolation units for high-level containment situations.

a. Eligible Applicants: Limited

b. NOFO Type: Cooperative Agreement

c. Approximate Number of Awards: 3

d. Total Period of Performance Funding: $3,100,000 Throughout the period of performance, CDC’s commitment to continuation of awards will be conditional on the availability of funds, evidence of satisfactory progress by the recipient (as documented in required reports), and the determination that continued funding is in the best interest of the Federal government.

e. Average One Year Award Amount: $1,033,333

f. Total Period of Performance Length: 3

g. Estimated Award Date: 09/30/2019

h. Cost Sharing and / or Matching Requirements: N Cost sharing/matching not required for this program.

Part II. Full Text A. Funding Opportunity Description

Part II. Full Text

1. Background

a. Overview The NETEC hospitals: Emory University, the University of Nebraska Medical Center, and the New York Health and Hospitals Corporation, Bellevue Hospital Center, to be funded through CDC, will increase the competency of health care and public health workers and the capability of health care facilities to deliver safe, efficient, and effective Ebola patient care through the nationwide, regional network for Ebola and other infectious diseases. Comprised of staff from hospitals that have successfully evaluated and treated Ebola patients in the U.S., and in collaboration with staff from CDC, the NETEC hospitals will offer expertise, education, training, technical assistance, peer review assessments, recognition reporting, and, if feasible, certification to regional Ebola and other special pathogen treatment centers, state- and jurisdiction-based Ebola treatment centers, and assessment hospitals.

This funding opportunity will support a consortium agreement, under which each recipient collaborates with one or more other organizations in carrying out the cooperative agreement-supported activities of the NETEC hospitals. The recipients, as the direct and primary recipients of cooperative agreement funds, are accountable to CDC for the performance of the project, the appropriate expenditure of cooperative agreement funds by all parties, applicable reporting requirements, and all other obligations of the recipient.

b. Statutory Authorities PH Service 301(a), 307, 317 as amended [42 U.S.C. 214, 242I, & 247b]

c. Healthy People 2030 Preparedness https://www.healthypeople.gov/2020/topics-objectives/topic/preparedness Healthcare Associated Infections https://www.healthypeople.gov/2020/topics-objectives/topic /healthcare-associated-infections Health Communication and Health Information Technology https://www.healthypeople.gov /2020/topics-objectives/topic/health-communication-and-health-information-technology

d. Other National Public Health Priorities and Strategies National Action Plan to Prevent Healthcare Associated Infections https://health.gov/hcq/prevent -hai-action-plan.asp

Global Health Security Agenda https://www.hhs.gov/about/agencies/oga/global-health-security /agenda/index.html

e. Relevant Work Since the 1960s, CDC has been engaged in infection control and healthcare safety. This work has led to improved technical innovation and guidelines, making US healthcare the safest in the world. Information on relevant work can be found here:

https://www.cdc.gov/infectioncontrol/index.html https://www.cdc.gov/infectioncontrol/guidelines/index.html https://www.cdc.gov/hicpac/

2. CDC Project Description

a. Approach

Bold indicates period of performance outcome.

Strategies and Activities Short-term

Outcomes Intermediate Outcomes

Long-Term Outcomes

Strategy A: Tailor Infection Prevention Control (IPC) needs for small and rural healthcare facilities.

· Increased knowledge of the gaps and opportunities to optimize

· Increased ability of small and rural healthcare facilities to

· Improved IPC capabilities and training in small and rural healthcare facilities https://www.healthypeople.gov/2020/topics-objectives/topic/preparedness https://www.healthypeople.gov/2020/topics-objectives/topic/healthcare-associated-infections https://www.healthypeople.gov/2020/topics-objectives/topic/healthcare-associated-infections https://www.healthypeople.gov/2020/topics-objectives/topic/health-communication-and-health-information-technology https://www.healthypeople.gov/2020/topics-objectives/topic/health-communication-and-health-information-technology https://health.gov/hcq/prevent-hai-action-plan.asp https://health.gov/hcq/prevent-hai-action-plan.asp https://www.hhs.gov/about/agencies/oga/global-health-security/agenda/index.html https://www.hhs.gov/about/agencies/oga/global-health-security/agenda/index.html https://www.cdc.gov/infectioncontrol/guidelines/index.html

IPC in small and rural healthcare facilities identify materials developed to address gaps

· Improved access to real-time IPC consultation services for small and rural healthcare facilities

Strategy B: Evaluating failure modes and human factors associated with IPC in isolation rooms during simulated patient care activities, including personal protective equipment (PPE) use, environmental cleaning, and use of devices and equipment

· Increased understanding of the failure modes and human factors associated with

IPC

· Enabled facilities and HCPs to assess risks and measure gaps in their IPC activities.

· Improved assessment of

HCP

competency in regards to IPC best practices

· Improved IPC best practices and training amongst HCP to reduce HAIs and patient harm

· Improved understanding of failure of PPE that will translate into better designs and training.

Strategy C: Identify processes and strategies to convert existing environments into safe isolation units for high-level containment situations.

· Improved understanding of:

o Structural capabilities and barriers encountered in implementing IPC for high-level containment situations o Barriers that facilities might have for identifying travel or other potential

· Facilities increased ability to identify resources to:

o Establish or modify existing environments into safe isolation units for high-level containment situations

· Triage and isolate patients who may need

· Increased capacity for facilities to implement guidance that is scalable and generalizable to utilize existing infrastructure to meet the demands of a high-level containment situation.

· Improved capacity and training of facilities to Identify, Isolate and Inform public health officials of a potential patient who may require high-level containment exposures for special pathogens.

high-level containment and, inform public health officials

i. Purpose This CDC cooperative agreement will increase the competency of health care and public health workers and the capability of health care facilities to deliver safe, efficient, and effective Ebola patient care through the nationwide, regional network for Ebola and other infectious diseases.

NETEC will offer expertise, education, training, technical assistance, peer review assessments, recognition reporting, and, if feasible, certification to regional Ebola and other special pathogen treatment centers, state- and jurisdiction-based Ebola treatment centers, and assessment hospitals.

ii. Outcomes Strategy A: Tailor Infection Prevention Control (IPC) needs for small and rural healthcare facilities.

Increase knowledge of the gaps and opportunities to optimize IPC in small and rural healthcare facilities.

Increased ability of small and rural healthcare facilities to identify materials developed to address gaps.

Strategy B: Evaluating failure modes and human factors associated with IPC in isolation rooms during simulated patient care activities, including PPE use, environmental cleaning, and use of devices and equipment

Increased understanding of the failure modes and human factors associated with

IPC

Enable facilities and HCPs to assess risks and measure gaps in their IPC activities Improved assessment of HCP competency in regards to IPC best practices

Strategy C: Identify processes and strategies to convert existing environments into safe isolation units for high-level containment situations

Improved understanding of:

Structural capabilities and barriers encountered in implementing IPC for high-level containment situations Barriers that facilities might have for identifying travel or other potential exposures for special pathogens.

Facilities increased ability to identify resources to:

Establish or modify existing environments into safe isolation units for high-level containment situations o Triage and isolate patients who may need high-level containment and, inform public health officials

Increased capacity and training for facilities to implement guidance that is scalable and generalizable to utilize existing infrastructure to meet the demands of a high-level containment situation.

Improved capacity of facilities to Identify, Isolate and Inform public health officials of a potential patient who may require high-level containment

iii. Strategies and Activities Each applicant will apply and be funded for one of the following strategies:

Strategy A: Tailor Infection Prevention Control (IPC) needs for small and rural healthcare facilities Activities:

i. Assess IPC needs of small and rural healthcare facilities

a. Identify specific setting that require tailored tools and resources

ii. Summarize opportunities for optimized IPC in small and rural healthcare facilities

a. Cross-walk existing large hospital IPC resources with small and rural healthcare facility needs summary

iii. Develop a suite of tailored resources

a. Develop templates addressing identified gaps

b. Field test and validate developed materials including input from small and rural facility users

c. Make available for free online, and mobile-friendly as appropriate

iv. Devise and pilot a real-time IPC consultation service for small and rural healthcare facilities

a. Research and identify platforms that would be appropriate for remote IPC consultation

b. Pilot identified platforms with several small and rural healthcare facilities

c. Provide a guide on how to implement real-time IPC consultation

v. Provide training to implement all tools developed

Strategy B: Evaluating failure modes and human factors associated with IPC in isolation rooms during simulated patient care activities, including personal protective equipment (PPE) use, environmental cleaning, and use of devices and equipment

Activities:

i. Utilize augmented reality to observe devices and equipment as well as behaviors and practices in a simulated clinical setting.

a. Scale simulations to include additional patient care activities, treatment and diagnostic activities across the range of healthcare delivery (e.g., crowding of the room with equipment and additional people, acuity of care, and simulated distractions).

b. Provide a technical report that summarizes the findings and recommendations of failure modes and human factors associated with PPE design and training.

ii. Develop a methodology to measure competency of healthcare personnel during IPC activities

a. Develop an analytical approach to identify failure modes and measure competency

b. Describe failure modes of both individual devices and behaviors and practices

c. Develop and pilot test materials to address areas of need and/or gaps that are user friendly

d. Finalize materials to address areas of need and/or gaps and ensure they are available for free online.

iii. Optimize healthcare personnel’s (HCP) ability to asses risks and identify correct procedures for IPC

a. Assess and measure gaps in IPC behaviors during these simulations

b. Implement a knowledge, attitudes, and perception assessment (or focus group) to determine areas of need.

c. Summarize observations and provide recommendations for best practices on observing, training, and measuring IPC competency of healthcare personnel

iv. Provide updated/improved IPC training based on findings

Strategy C: Identify processes and strategies to convert existing environments into safe isolation units for high-level containment situations.

Activities:

i. Establish processes that need to be implemented for high-level containment situations.

a. Identify necessary structural capabilities and common barriers encountered in implementing IPC with existing infrastructure.

b. Develop guidance that is scalable for healthcare facilities to utilize existing infrastructure to meet the demands of a high-level containment situation.

ii. Develop tools for cost estimates to make infrastructure modifications.

a. Develop interactive tools (e.g., cost and time estimators) to facilitate planning and implementation

iii. Have a process to identify, then to safely isolate patients appropriate for high-level containment at initial triage in an appropriate space, and a process to immediately inform public health officials

a. Develop and pilot approaches and templates to institute the identify, isolate, and inform framework

b. Develop an implementation toolkit for effectively implementing the identify, isolate, and inform framework, including in frontline and assessment facilities

iv. Make all materials available for free online and user friendly

v. Provide training to implement all tools developed

1. Collaborations

a. With other CDC programs and CDC-funded organizations:

The limited source justification approach to engage the NETEC consortium was selected specifically because of the unique opportunity to collaborate and engage among consortium members due to the unique structure of the consortium that enables frequent and deep collaboration across member entities without having to establish new relationships. The consortium can collaborate within its three members and also externally with CDC-funded partners such as state and local health departments and other national non-profit health associations, and these collaborations can be elected by the recipients as the context and CDC partners may deem appropriate over the life of the project.

b. With organizations not funded by CDC:

2. Target Populations The target population is healthcare personnel in the nation’s healthcare facilities that work in low resource settings (in particular small and rural healthcare facilities) and lack the structure of a proper IPC program, preventing transmission of communicable diseases in healthcare settings.

The ultimate goal of this project is to improve patient safety and reduce healthcare-associated infections (HAIs) for all patients who seek medical care.

a. Health Disparities The target population is healthcare personnel in the nation’s healthcare facilities that work in low resource settings (in particular small and rural healthcare facilities) and lack the structure of a proper Infection Prevention and Control (IPC) program, preventing transmission of communicable diseases in healthcare settings. These facilities face challenges in IPC that are complicated by frequent staff turnover, vacancies, isolated/hardship locations, lack of training and resources, and leadership support. IPC staff are usually not able to focus exclusively on IPC and are assigned many other roles and responsibilities. In addition, there is no centralized or standardized training for IPC within these facilities. The lack of IPC in some of the nations healthcare facilities puts the patients and healthcare personnel at risk of infection. The Cooperative Agreement will reduce these health disparities and improve the following:

* IPC capabilities in small and rural healthcare facilities.

* IPC best practices amongst HCP to reduce HAIs and patient harm.

* Capacity for facilities to implement guidance that is scalable to utilize existing infrastructure to meet the demands of a high level containment situation.

* Capacity of facilities to identify, isolate and inform public health officials of a potential patient who may require high-level containment.

The outcomes achieved by the recipients of this cooperative agreement will reduce HAIs and improve patient care in small and rural healthcare facilities which in turn will improve health outcomes for populations served by these facilities (e.g. rural and tribal populations).

iv. Funding Strategy Recipient A Funding for Budget Period: $300,000.00 Recipient B Funding for Budget Period: $366,666.66 Recipient C Funding for Budget Period: $366,666.66 Ceiling: $4,100,000.00 Floor: $1.00

b. Evaluation and Performance Measurement

i. CDC Evaluation and Performance Measurement Strategy Recipients are expected to report the performance measures, and at the time of continuation applications when the emphasis will be on the narrative reporting. Recipients will also be expected to share progress of implementation of work plans (including but not limited to hiring of personnel or execution of contracts) as well as status of spending during regularly scheduled (i.e., at least quarterly) updates to CDC program personnel.

Strategy A - Tailor Infection Prevention Control (IPC) needs for small and rural healthcare facilities

Describes a project management approach for tracking progress on activities and proposed evaluation and performance measures.

Provide results of small and rural healthcare facilities assessed for IPC needs.

Provide results of a follow up assessment of small and rural hospitals after the implementation of tools developed by the recipient.

Provide a summary of the piloted of a real-time IPC consultation service for small and rural healthcare facilities.

Provide number of trainings to implement all tools developed.

Provide the status of all materials available for free online and user friendly

Strategy B - Evaluating failure modes and human factors associated with IPC in isolation rooms during simulated patient care activities, including personal protective equipment (PPE) use, environmental cleaning, and use of devices and equipment

Describes a project management approach for tracking progress on activities and proposed evaluation and performance measures.

Provide a summary of the failures observed using augmented reality.

Report on developed methodology to measure competency of healthcare personnel during IPC activities.

Provide an assessment of improved healthcare personnel’s (HCP) ability to asses risks and identify correct procedures for IPC.

Provide updated/improved IPC training-based on findings.

Provide the status of all materials available for free online and user friendly

Strategy C - Identify processes and strategies to convert existing environments into safe isolation units for high-level containment situations:

Describes a project management approach for tracking progress on activities and proposed evaluation and performance measures.

Provide a detailed report on established processes to be implemented for high-level containment situations.

Provide the number of tools developed for cost estimates to make infrastructure modifications.

Provide a summary to identify, then to safely isolate patients appropriate for high-level containment at initial triage in an appropriate space, and a process to immediately inform public health officials

Provide number of trainings to implement all tools developed

Provide the status of all materials available for free online and user friendly

ii. Applicant Evaluation and Performance Measurement Plan Applicants must provide an evaluation and performance measurement plan that demonstrates how the recipient will fulfill the requirements described in the CDC Evaluation and Performance Measurement and Project Description sections of this NOFO. At a minimum, the plan must describe:

How applicant will collect the performance measures, respond to the evaluation questions, and use evaluation findings for continuous program quality improvement.

How key program partners will participate in the evaluation and performance measurement planning processes.

Available data sources, feasibility of collecting appropriate evaluation and performance data, and other relevant data information (e.g., performance measures proposed by the applicant)

Plans for updating the Data Management Plan (DMP), if applicable, for accuracy throughout the lifecycle of the project. The DMP should provide a description of the data that will be produced using these NOFO funds; access to data; data standards ensuring released data have documentation describing methods of collection, what the data represent, and data limitations; and archival and long-term data preservation plans.

For more information about CDC’s policy on the DMP, see https://www.cdc.gov/grants/additionalrequirements/ar-25.html.

Where the applicant chooses to, or is expected to, take on specific evaluation studies, they should be directed to:

Describe the type of evaluations (i.e., process, outcome, or both).

Describe key evaluation questions to be addressed by these evaluations.

https://www.cdc.gov/grants/additionalrequirements/ar-25.html

Describe other information (e.g., measures, data sources).

Recipients will be required to submit a more detailed Evaluation and Performance Measurement plan, including a DMP, if applicable, within the first 6 months of award, as described in the Reporting Section of this NOFO.

c. Organizational Capacity of Recipients to Implement the Approach The applicants will address the consortium member’s current capacity to successfully implement the proposed project and associated activities, including describing the staff and other infrastructure already in place on which to build and meet period of performance outcomes.

Successful applicants will have the capacity to:

i. Conduct effective program planning, evaluation, performance monitoring, financial reporting, budget management and administration, and personnel management.

ii. Operate a financial management system that will enable:

a. Proper funds management and segregation of funds by program as required by

45 CFR 75.302;

b. Preparation of reports as required by general and program-specific terms and conditions;

c. Tracing of funds to a level of expenditure adequate to establish compliance with federal statutes, regulations, and terms/conditions of the federal award

iii. Implement activities, evaluation plans, and staffing plans using a project management structure sufficient to clearly define staff roles and achieve project outcomes.

iv. Manage required procurement efforts.

v. Write and award contracts in accordance with applicable grants regulations.

d. Work Plan Applicants must clearly identify the outcomes they expect to achieve by the end of the period of performance and provide a clear and concise description of the strategies and activities they used to achieve the project’s outcome.

Applicant will briefly introduce the activity (ies) being proposed and describe what the expected output (e.g. milestones) will be over the first 12 months of the project and a higher level description for each subsequent year.

Applicant will define the expected outcomes that align with resolving the problem of closing the gaps. The outcomes should define what changes and improvements will occur in healthcare facilities and public health departments. Outcomes should be well defined, specific, measureable, and realistically achievable and contribute to closing the gaps identified in the narrative. Ideally, outcomes should link to planned activities, quantify the targeted change, and include an estimated timeline for achieving the change. The applicant can include as many outcomes as needed.

Applicant will list the intermediate activities the consortium will undertake, including tasks and estimated start and end dates, which will lead to the associated outcomes and contribute to resolving the identified issue or problem. The applicant can include as many planned activities as needed.

Applicant will list the proposed outputs that will be produced as a result of the planned activities, such as the development of metrics to evaluate health care facilities lesson learned.

The applicant can include as many planned outputs as needed

e. CDC Monitoring and Accountability Approach Monitoring activities include routine and ongoing communication between CDC and recipients, site visits, and recipient reporting (including work plans, performance, and financial reporting).

Consistent with applicable grants regulations and policies, CDC expects the following to be included in post-award monitoring for grants and cooperative agreements:

Tracking recipient progress in achieving the desired outcomes.

Ensuring the adequacy of recipient systems that underlie and generate data reports.

Creating an environment that fosters integrity in program performance and results.

Monitoring may also include the following activities deemed necessary to monitor the award:

Ensuring that work plans are feasible based on the budget and consistent with the intent of the award.

Ensuring that recipients are performing at a sufficient level to achieve outcomes within stated timeframes.

Working with recipients on adjusting the work plan based on achievement of outcomes, evaluation results and changing budgets.

Monitoring performance measures (both programmatic and financial) to assure satisfactory performance levels.

Monitoring and reporting activities that assist grants management staff (e.g., grants management officers and specialists, and project officers) in the identification, notification, and management of high-risk recipients.

f. CDC Program Support to Recipients (THIS SECTION APPLIES ONLY TO

COOPERATIVE AGREEMENTS)

Technical support SME support Technical document review

B. Award Information

1. Funding Instrument Type: Cooperative Agreement CDC's substantial involvement in this program appears in the CDC Program Support to Recipients Section.

2. Award Mechanism: U38 U38 – Cooperative Agreements to develop or improve facets of public health information in cooperation with eligile applicants: CDC National Infection Control Strengthening

3. Fiscal Year: 2019

4. Approximate Total Fiscal Year Funding: $3,100,000

5. Approximate Period of Performance Funding: $3,100,000

This amount is subject to the availability of funds.

Throughout the period of performance, CDC’s commitment to continuation of awards will be conditional on the availability of funds, evidence of satisfactory progress by the recipient (as documented in required reports), and the determination that continued funding is in the best interest of the Federal government.

Estimated Total Funding: $3,100,000

6. Approximate Period of Performance Length: 3 year(s)

7. Expected Number of Awards: 3

8. Approximate Average Award: $1,033,333 Per Project Period

9. Award Ceiling: $4,100,000 Per Project Period

This amount is subject to the availability of funds.

10. Award Floor: $1 Per Project Period

11. Estimated Award Date: 09/30/2019

12. Budget Period Length: 36 month(s)

Throughout the project period, CDC will continue the award based on the availability of funds, the evidence of satisfactory progress by the recipient (as documented in required reports), and the determination that continued funding is in the best interest of the federal government. The total number of years for which federal support has been approved (project period) will be shown in the “Notice of Award.” This information does not constitute a commitment by the federal government to fund the entire period. The total period of performance comprises the initial competitive segment and any subsequent non-competitive continuation award(s).

13. Direct Assistance Direct Assistance (DA) is available through this NOFO.

C. Eligibility Information

1. Eligible Applicants

Eligibility Category: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Others (see text field entitled "Additional Information on Eligibility" for clarification)

Additional Eligibility Category:

Government Organizations:

State controlled institutions of higher education

2. Additional Information on Eligibility In addition to noted above categories, state controlled institutions of higher education may also apply.

Eligible applicants are limited exclusively to the three member institutions of the National Ebola Training and Education Center (NETEC), a consortium of three healthcare institutions in the US that have successfully treated patients with Ebola virus disease: (1) Emory University,

(2) the University of Nebraska Medical Center/Nebraska Medicine, and (3) New York City Health and Hospitals/Bellevue.

3. Justification for Less than Maximum Competition The NETEC consortium members leverage their unique expertise, resources, and experiences to assess and assist healthcare facility readiness, educate and train providers, provide real-time technical assistance, and build a research infrastructure in the US. Combined with strong existing and new partnerships with federal agencies, these NETEC members ultimately strengthen our nation's health care and public health systems for the next emerging infectious disease threat.

4. Cost Sharing or Matching Cost Sharing / Matching Requirement: No Cost sharing/matching not required for this program.

5. Maintenance of Effort Maintenance of effort is not required for this program.

D. Application and Submission Information

1. Required Registrations An organization must be registered at the three following locations before it can submit an application for funding at www.grants.gov.

a. Data Universal Numbering System:

All applicant organizations must obtain a Data Universal Numbering System (DUNS) number.

A DUNS number is a unique nine-digit identification number provided by Dun & Bradstreet (D&B). It will be used as the Universal Identifier when applying for federal awards or cooperative agreements.

The applicant organization may request a DUNS number by telephone at 1-866-705-5711 (toll free) or internet at http:// fedgov.dnb. com/ webform/ displayHomePage.do. The DUNS number will be provided at no charge.

If funds are awarded to an applicant organization that includes sub-recipients, those sub-recipients must provide their DUNS numbers before accepting any funds.

b. System for Award Management (SAM):

The SAM is the primary registrant database for the federal government and the repository into which an entity must submit information required to conduct business as a recipient. All applicant organizations must register with SAM, and will be assigned a SAM number. All information relevant to the SAM number must be current at all times during which the applicant has an application under consideration for funding by CDC. If an award is made, the SAM information must be maintained until a final financial report is submitted or the final payment is received, whichever is later. The SAM registration process can require 10 or more business days, and registration must be renewed annually. Additional information about registration procedures may be found at https://www.sam.gov/SAM/.

c. Grants.gov:

The first step in submitting an application online is registering your organization at www.grants.gov, the official HHS E-grant Web site. Registration information is located at the "Applicant Registration" option at www.grants.gov.

All applicant organizations must register at www.grants.gov. The one-time registration process usually takes not more than five days to complete. Applicants should start the registration process as early as possible.

Step System Requirements Duration Follow Up 1 Data

Universal Number System

(DUNS)

1. Click on http:// fedgov.dnb.com/ webform

2. Select Begin DUNS search/request process

3. Select your country or territory and follow the instructions to obtain your DUNS 9-digit #

1-2 Business Days

To confirm that you have been issued a new DUNS number check online at (http:// fedgov.dnb.com/ webform) or call https://www.grants.gov/ http://fedgov.dnb.com/webform/displayHomePage.do https://www.sam.gov/SAM/ https://grants.gov/ https://www.grants.gov/ http://www.grants.gov https://www.grants.gov/ http://fedgov.dnb.com/webform http://fedgov.dnb.com/webform http://fedgov.dnb.com/webform http://fedgov.dnb.com/webform http://fedgov.dnb.com/webform

4. Request appropriate staff member(s) to obtain DUNS number, verify & update information under DUNS number

1-866-705-5711

2 System for Award Management

(SAM)

formerly Central Contractor Registration

(CCR)

1. Retrieve organizations DUNS number

2. Go to https://www.sam.gov/SAM/ and designate an E-Biz POC (note CCR username will not work in SAM and you will need to have an active SAM account before you can register on grants.gov)

3-5 Business Days but up to 2 weeks and must be renewed once a year

For SAM Customer Service Contact https://fsd.gov/ fsd-gov/ home.do Calls:

866-606-8220

3 Grants.gov 1. Set up an individual account in Grants.gov using organization new DUNS number to become an authorized organization representative (AOR)

2. Once the account is set up the E-BIZ POC will be notified via email

3. Log into grants.gov using the password the E-BIZ POC received and create new password

4. This authorizes the AOR to submit applications on behalf of the organization

Same day but can take 8 weeks to be fully registered and approved in the system (note, applicants

MUST

obtain a

DUNS

number and

SAM

account before applying on grants.gov)

Register early!

Log into grants.gov and check AOR status until it shows you have been approved

2. Request Application Package Applicants may access the application package at www.grants.gov.

3. Application Package Applicants must download the SF-424, Application for Federal Assistance, package associated with this notice of funding opportunity at www.grants.gov.

4. Submission Dates and Times https://www.sam.gov/SAM/ https://fsd.gov/fsd-gov/home.do https://fsd.gov/fsd-gov/home.do https://fsd.gov/fsd-gov/home.do

If the application is not submitted by the deadline published in the NOFO, it will not be processed. Office of Grants Services (OGS) personnel will notify the applicant that their application did not meet the deadline. The applicant must receive pre-approval to submit a paper application (see Other Submission Requirements section for additional details). If the applicant is authorized to submit a paper application, it must be received by the deadline provided by

OGS.

a. Letter of Intent Deadline (must be emailed or postmarked by) Due Date for Letter of Intent: N/A

b. Application Deadline Due Date for Applications: 08/05/2019 , 11:59 p.m. U.S. Eastern Standard Time, at www.grants.gov. If Grants.gov is inoperable and cannot receive applications, and circumstances preclude advance notification of an extension, then applications must be submitted by the first business day on which grants.gov operations resume.

Date for Information Conference Call

5. CDC Assurances and Certifications All applicants are required to sign and submit “Assurances and Certifications” documents indicated at http://wwwn.cdc.gov/ grantassurances/ (S(mj444mxct51lnrv1hljjjmaa)) /Homepage.aspx.

Applicants may follow either of the following processes:

Complete the applicable assurances and certifications with each application submission, name the file “Assurances and Certifications” and upload it as a PDF file with at www.grants.gov

Complete the applicable assurances and certifications and submit them directly to CDC on an annual basis at http://wwwn.cdc.gov/ grantassurances/ (S(mj444mxct51lnrv1hljjjmaa))/ Homepage.aspx

Assurances and certifications submitted directly to CDC will be kept on file for one year and will apply to all applications submitted to CDC by the applicant within one year of the submission date.

Risk Assessment Questionnaire Requirement CDC is required to conduct pre-award risk assessments to determine the risk an applicant poses to meeting federal programmatic and administrative requirements by taking into account issues such as financial instability, insufficient management systems, non-compliance with award conditions, the charging of unallowable costs, and inexperience. The risk assessment will include an evaluation of the applicant’s CDC Risk Questionnaire, located at https://www.cdc.gov/grants/documents/PPMR-G-CDC-Risk-Questionnaire.pdf, as well as a review of the applicant’s history in all available systems; including OMB-designated repositories of government-wide eligibility and financial integrity systems (see 45 CFR https://www.grants.gov http://wwwn.cdc.gov/grantassurances/(S(mj444mxct51lnrv1hljjjmaa))/Homepage.aspx http://wwwn.cdc.gov/grantassurances/(S(mj444mxct51lnrv1hljjjmaa))/Homepage.aspx https://www.grants.gov http://wwwn.cdc.gov/grantassurances/(S(mj444mxct51lnrv1hljjjmaa))/Homepage.aspx http://wwwn.cdc.gov/grantassurances/(S(mj444mxct51lnrv1hljjjmaa))/Homepage.aspx https://www.cdc.gov/grants/documents/PPMR-G-CDC-Risk-Questionnaire.pdf

75.205(a)), and other sources of historical information. These systems include, but are not limited to: FAPIIS (https://www.fapiis.gov/), including past performance on federal contracts as per Duncan Hunter National Defense Authorization Act of 2009; Do Not Pay list; and System for Award Management (SAM) exclusions.

CDC requires all applicants to complete the Risk Questionnaire, OMB Control Number 0920- 1132 annually. This questionnaire, which is located at https://www.cdc.gov/grants/documents/PPMR-G-CDC-Risk-Questionnaire.pdf, along with supporting documentation must be submitted with your application by the closing date of the Notice of Funding Opportunity Announcement. If your organization has completed CDC’s Risk Questionnaire within the past 12 months of the closing date of this NOFO, then you must submit a copy of that questionnaire, or submit a letter signed by the authorized organization representative to include the original submission date, organization’s EIN and DUNS.

When uploading supporting documentation for the Risk Questionnaire into this application package, clearly label the documents for easy identification of the type of documentation. For example, a copy of Procurement policy submitted in response to the questionnaire may be labeled using the following format: Risk Questionnaire Supporting Documents _ Procurement Policy.

Duplication of Efforts Applicants are responsible for reporting if this application will result in programmatic, budgetary, or commitment overlap with another application or award (i.e. grant, cooperative agreement, or contract) submitted to another funding source in the same fiscal year.

Programmatic overlap occurs when (1) substantially the same project is proposed in more than one application or is submitted to two or more funding sources for review and funding consideration or (2) a specific objective and the project design for accomplishing the objective are the same or closely related in two or more applications or awards, regardless of the funding source. Budgetary overlap occurs when duplicate or equivalent budgetary items (e.g., equipment, salaries) are requested in an application but already are provided by another source.

Commitment overlap occurs when an individual’s time commitment exceeds 100 percent, whether or not salary support is requested in the application. Overlap, whether programmatic, budgetary, or commitment of an individual’s effort greater than 100 percent, is not permitted.

Any overlap will be resolved by the CDC with the applicant and the PD/PI prior to award.

Report Submission: The applicant must upload the report in Grants.gov under “Other Attachment Forms.” The document should be labeled: "Report on Programmatic, Budgetary, and Commitment Overlap.”

6. Content and Form of Application Submission Applicants are required to include all of the following documents with their application package at www.grants.gov.

7. Letter of Intent N/A https://www.cdc.gov/grants/documents/PPMR-G-CDC-Risk-Questionnaire.pdf

8. Table of Contents (There is no page limit. The table of contents is not included in the project narrative page limit.): The applicant must provide, as a separate attachment, the “Table of Contents” for the entire submission package.

Provide a detailed table of contents for the entire submission package that includes all of the documents in the application and headings in the "Project Narrative" section. Name the file "Table of Contents" and upload it as a PDF file under "Other Attachment Forms" at www.grants.gov.

9. Project Abstract Summary (Maximum 1 page) A project abstract is included on the mandatory documents list and must be submitted at www.grants.gov. The project abstract must be a self-contained, brief summary of the proposed project including the purpose and outcomes. This summary must not include any proprietary or confidential information. Applicants must enter the summary in the "Project Abstract Summary" text box at www.grants.gov.

10. Project Narrative (Unless specified in the "H. Other Information" section, maximum of 20 pages, single spaced, 12 point font, 1-inch margins, number all pages. This includes the work plan. Content beyond the specified page number will not be reviewed.)

Applicants must submit a Project Narrative with the application forms. Applicants must name this file “Project Narrative” and upload it at www.grants.gov. The Project Narrative must include all of the following headings (including subheadings): Background, Approach, Applicant Evaluation and Performance Measurement Plan, Organizational Capacity of Applicants to Implement the Approach, and Work Plan. The Project Narrative must be succinct, self-explanatory, and in the order outlined in this section. It must address outcomes and activities to be conducted over the entire period of performance as identified in the CDC Project Description section. Applicants should use the federal plain language guidelines and Clear Communication Index to respond to this Notice of Funding Opportunity. Note that recipients should also use these tools when creating public communication materials supported by this NOFO. Failure to follow the guidance and format may negatively impact scoring of the application.

a. Background Applicants must provide a description of relevant background information that includes the context of the problem (See CDC Background).

b. Approach

i. Purpose Applicants must describe in 2-3 sentences specifically how their application will address the public health problem as described in the CDC Background section.

https://www.grants.gov https://www.grants.gov

ii. Outcomes Applicants must clearly identify the outcomes they expect to achieve by the end of the project period, as identified in the logic model in the Approach section of the CDC Project Description.

Outcomes are the results that the program intends to achieve and usually indicate the intended direction of change (e.g., increase, decrease).

iii. Strategies and Activities Applicants must provide a clear and concise description of the strategies and activities they will use to achieve the period of performance outcomes. Applicants must select existing evidence-based strategies that meet their needs, or describe in the Applicant Evaluation and Performance Measurement Plan how these strategies will be evaluated over the course of the project period.

See the Strategies and Activities section of the CDC Project Description.

1. Collaborations Applicants must describe how they will collaborate with programs and organizations either internal or external to CDC. Applicants must address the Collaboration requirements as described in the CDC Project Description.

2. Target Populations and Health Disparities Applicants must describe the specific target population(s) in their jurisdiction and explain how such a target will achieve the goals of the award and/or alleviate health disparities. The applicants must also address how they will include specific populations that can benefit from the program that is described in the Approach section. Applicants must address the Target Populations and Health Disparities requirements as described in the CDC Project Description.

c. Applicant Evaluation and Performance Measurement Plan Applicants must provide an evaluation and performance measurement plan that demonstrates how the recipient will fulfill the requirements described in the CDC Evaluation and Performance Measurement and Project Description sections of this NOFO. At a minimum, the plan must describe:

How applicant will collect the performance measures, respond to the evaluation questions, and use evaluation findings for continuous program quality improvement. The Paperwork Reduction Act of 1995 (PRA): Applicants are advised that any activities involving information collections (e.g., surveys, questionnaires, applications, audits, data requests, reporting, recordkeeping and disclosure requirements) from 10 or more individuals or non-Federal entities, including State and local governmental agencies, and funded or sponsored by the Federal Government are subject to review and approval by the Office of Management and Budget. For further information about CDC’s requirements under PRA see https://www.cdc.gov/od/science/integrity/reducePublicBurden/.

How key program partners will participate in the evaluation and performance measurement planning processes.

https://www.cdc.gov/od/science/integrity/reducePublicBurden/

Available data sources, feasibility of collecting appropriate evaluation and performance data, data management plan (DMP), and other relevant data information (e.g., performance measures proposed by the applicant).

Where the applicant chooses to, or is expected to, take on specific evaluation studies, they should be directed to:

Describe the type of evaluations (i.e., process, outcome, or both).

Describe key evaluation questions to be addressed by these evaluations.

Describe other information (e.g., measures, data sources).

Recipients will be required to submit a more detailed Evaluation and Performance Measurement plan (including the DMP elements) within the first 6 months of award, as described in the Reporting Section of this NOFO.

d. Organizational Capacity of Applicants to Implement the Approach Applicants must address the organizational capacity requirements as described in the CDC Project Description.

11. Work Plan (Included in the Project Narrative’s page limit) Applicants must prepare a work plan consistent with the CDC Project…