CDC-RFA-CK15-150507SUPP17 FINAL 07 21 17.docx

DOCX document 132 KB Posted

Attached to
Addressing Ebola and other Highly Infectious Diseases Internationally
Opportunity number
CDC-RFA-CK15-150507SUPP17
Issued by

About this file

Addressing Ebola and other Highly Infectious Diseases Internationally,

View the file

Other files

On GovTribe

Work with this file

  • Download the original file
  • Contacts named in this file
  • Similar government files
  • Ask GovTribe AI about this file

Text version

Centers for Disease Control and Prevention (CDC) Procurement and Grants Office Instructions for Preparing an Annual Performance Report (APR) Catalog of Federal Domestic Assistance (CFDA): 93.099 and 93.818 Funding Opportunity Announcement (FOA) Number*: CDC-RFA-CK15-150507SUPP17 Addressing Ebola and other Highly Infectious Diseases Internationally, Grant Number 6NU50GH001894-01

Eligibility:

This award will be a continuation of funds intended only for the recipient previously awarded under CDC-RFA-CK15-1505, Addressing Ebola and other Highly Infectious Diseases Internationally, Grant Number 6NU50GH001894-01.

Please contact the assigned Grants Management Specialist/Officer or Project Officer if there are any questions. Due date is September 21, 2017 by 11:59 PM on Grants.gov.

Application Submission:

General Application Packet Tips:

· Properly label each item of the application packet

· Each section should use 1.5 spacing with one-inch margins

· Number all narrative pages only

· The application must not exceed 45 pages excluding administrative reporting; allowed, but web links are allowed

· Where the instructions on the forms conflict with these instructions, follow these instructions

1. CDC requires the use of PDF format for ALL attachments.

2. Use of file formats other than PDF may result in the file being unreadable by CDC staff.

3. Directions for creating PDF files can be found on www.Grants.gov

Checklist of required contents of application packet:

1. SF-424 Application for Federal Domestic Assistance-Short Organizational Form

2. SF-424A Budget Information-Non-Construction Programs

3. Budget Justification

4. Indirect Cost Rate Agreement

5. Project Narrative

Instructions for accessing and completing required contents of the application package:

a) Go to: www.Grants.gov

b) Select: “Apply for Grants”

c) Select: “Step 1: Download a Grant Application”

d) Insert the CDC-RFA-CK15-150507SUPP17 only

e) Download application package and complete all sections.

1. SF-424 Application for Federal Domestic Assistance-Short Organizational Form:

Complete all sections:

A. In addition to inserting the legal name of your organization in Block #5a, insert the CDC Award Number provided in the CDC Notice of Award. Failure to provide your award number could cause delay in processing your application.

B. Please insert your organization’s Business Official information in Block #8.

SPECIAL NOTE: Items 2, 3, and 4 should be attached to the application through the “Mandatory Documents” section of the “Grant Application” page. Select “Other Attachments Form” and attach as a PDF file.

2. SF-424A Budget Information and Justification:

A. Download the form from www.grants.gov.

B. Complete all applicable sections.

C. The proposed budget should be based on the federal funding level stated in the letter from CDC.

D. In a separate narrative, provide a detailed, line-item budget justification of the funding amount requested to support the activities to be carried out with those funds. Attach in the “Mandatory Documents” box under “Budget Narrative Attachment Form.” Document needs to be in the PDF format.

E. The budget justification must be prepared in the general form, format, and to the level of detail as described in the CDC Budget Guidance. The sample budget guidance is provided on CDC’s internet at: http://www.cdc.gov/od/pgo/funding/grants/foamain.shtm.

F. For any new proposed subcontracts provide the information specified in the Budget Guidance.

G. When non-federal matching is required, provide a line-item list of non-federal contributions including source, amount, and/or value of third party contributions proposed to meet a matching requirement.

3. Indirect Cost Rate Agreement (This is not applicable to grantees subject to OMB Guidance A-21 – Educational Institutions. The rates stay the same as the first year award.):

A. If indirect costs are requested, include a copy of the current negotiated federal indirect cost rate agreement or a cost allocation plan approval letter for those Grantees under such a plan.

B. Clearly describe the method used to calculate indirect costs. Make sure the method is consistent with the Indirect Cost Rate Agreement.

C. To be entitled to use indirect cost rates, a rate agreement must be in effect at the start of the budget period.

D. If an Indirect Cost Rate Agreement is not in effect, indirect costs may be charged as direct if (1) this practice is consist with the grantee’s/applicant’s approved accounting practices; and (2) if the costs are adequately supported and justified. Please see the Budget Guidelines (http://www.cdc.gov/od/pgo/funding/grants/foamain.shtm) for additional information.

E. If applicable, attach in the “Mandatory Documents” box under “Other Attachments Form”. Name document “Indirect Cost Rate.”

4. Projects/Activities Requested and Narrative Instructions:

The following projects and activities are requested under this solicitation:

Project Title
Activities
Country/Office
Finalization of technical guidance document “Public Health Capacity Development at Ground Crossings and Cross-Border Collaboration."
The “Public Health Capacity Development at Ground Crossings and Cross-Border Collaboration" guidance document is being written jointly by the WHO and CDC and it is anticipated that, once finalized and cleared, it may become an annex to the International Health Regulations. WHO requires that global guidance documents go through a rigorous multinational subject matter expert review prior to clearance and publication. WHO currently does not have funding to support the expert consultation workshops and follow-up activities. This project seeks to support workshops and other activities that will enable the expert reviewers to convene and come to consensus on the Handbook's content so that the guidance document can be finalized and cleared by the WHO.

(Collaborating WHO unit is the Point-of-Entry group within the Health Emergencies Programme) WHO-Lyon

Ebola ring vaccination preparedness in Guinea, Liberia and Sierra Leone
The goal of the project is to provide continued support for Guinea, Liberia and Sierra Leone, countries at highest risk of future Ebola outbreaks, to prepare for successful Ebola vaccine deployment during 2017-2019, the pre-licensure time period. The specific objectives of pre-licensure emergency response vaccine deployment planning include: 1) assistance with submission of the vaccine protocol to regulatory authorities; 2) assessment and strengthening (which may include purchasing) of cold chain resources to support VSV vaccine storage at -60C; 3) mapping vaccine deployment logistics; 4) training of in-country staff as needed for ring vaccine preparedness; 5) integration of ring vaccination into country-specific response plans. The project would provide funding for protocol training of local staff including specific training for EPI staff on vaccine storage and transport and social mobilizers improving local capacity to manage vaccine implementation in the future.

A key concept of Ebola vaccine implementation is that it must be integrated within Ebola response activities. Therefore the project includes additional objectives to support integration of vaccine activities into the National Ebola Response plans in each country using WHO consultants to assist in updating language in the National EVD response plans. Additionally, the project proposes support for one emergency response exercise including ring vaccination in each country to ensure a well-trained workforce and incident command system.

Liberia

International Food Safety Authorities Network (INFOSAN) – Meeting of the INFOSAN Advocates.
As with other public health issues, a few advanced economies are leading the development of food safety systems and are vocal advocates for more international collaboration in the area of food safety data sharing and exchanges of best practices. This project aims at gathering some of the major INFOSAN Advocates (e.g. members from Canada, USA, Australia, New Zealand, Japan, a few countries in Europe). It is proposed to host a meeting that brings members from these countries together to discuss current best practices in information exchange to better manage food safety events and exchange ideas about how other INFOSAN members around the world can adopt similar practices to improve communication during international food safety emergencies.
HQ
Expanding EIS and IDSP
CDC plans to expand EIS and Frontline Epidemiology workforce training programs across India to increase Government of India engagement and ownership of workforce capacity building. Part of this plan includes partnering with WHO-India to establish a 3-year WHO-EIS (to train the polio transition staff) as part of the on the job programme. The goal is to train surveillance medical officers from WHO’s National Polio Surveillance Programme (NPSP) to assume more surveillance responsibilities toward more diseases as part of the polio legacy planning. CDC also supports the Govt of India’s effort to expand the Integrated Disease Surveillance Programme (IDSP) through partnership with WHO-India and key GHSA stakeholders. Efforts include identifying requirements, data sources, and standards for surveillance gathering and reporting.
India
Enhanced surveillance of emerging and novel variants of human influenza viruses in India
The purpose of this funding is to strengthen the surveillance system for emerging and novel variants of influenza viruses in India as part of the Global Health Security Agenda. This is important as India which is the largest country in the SEARO region reported number of avian influenza outbreaks in last year, although no human case of avian influenza has been reported so far. Further, the ongoing circulation of influenza A/H7N9 in bordering China also poses risk in the neighboring India which has the second largest population in the world. The objective of this project is to strengthen the surveillance especially among high risk groups like pregnant women, children, elderly and poultry workers in geographical areas not covered under existing systematic influenza surveillance. The WHO-SEARO would identify a suitable implementing partner based in India, who in consultation with the CDC India office can identify the gaps in current influenza surveillance system and identify potential surveillance sites to strengthen the influenza surveillance system in India to detect any novel variant of human influenza. The identified partner in consultation with SEARO and CDC India office would provide technical support to the identified sentinel sites to build their capacity for continued surveillance of human influenza virus with focus on high risk groups.
SEARO
Support to the Government of Mali to support the achievement of GHS/IHR laboratory, surveillance, workforce development and emergency management operations core capacities.
CDC Mali is providing technical assistance to the Government of Mali to support the achievement of GHS/IHR laboratory, surveillance, workforce development and emergency management operations core capacities. CDC Mali and WHO Mali are closely collaborating to support the strengthening of national capacity to detect and respond to public health emergencies. We are in discussions with the Minister for Health and Public Hygiene (MSHP) regarding the implementation of a Joint External Evaluation (JEE) of IHR Capacities.

Expected outcomes of the CDC-WHO joint support to the MSHP include revision of the National IDSR Guidelines to include SOPs for reporting, outbreak investigations and outbreak responses, regular reporting and data analyses at all levels of health system, syndromic surveillance, functional rapid response teams at district, regional and national levels, and the active engagement of communities in the detection and reporting of unusual health events. Expected Emergency Management Operations outcomes could include the implementation of functional exercises to test operational capacities of the national emergency operations program.

The GHSA funds ($250,000) will be used to facilitate WHO/CDC collaboration on GHS activities and will fund a position in the WHO Country Office to coordinate GHSA activities, including the JEE, with the Government of Mali and WHO and CDC.

Mali

Addressing Highly Infectious Diseases in Sierra Leone
Integrated Disease Surveillance and Response

The country has made notable progress in the revitalization of its surveillance and response capacity for the detection, documentation, and confirmation and reporting of priority diseases and other events of public health concern as well as in the use of data for directing public health interventions. Surveillance, as practiced within the WHO AFRO IDSR strategy, enables countries to build capacity for the generation and use of public health data. In terms of cross-border surveillance, only four out of the over 80 points of entry (PoEs) have all round services stipulated in the IHR. The bulk of travelers in and out of the country transit through non-designated crossing points. There is therefore need to support cross-border activities with cross-border engagement for information exchange, planning and joint response to supplement the screening in designated PoEs. To sustain gains made in implementing indicator based surveillance, there is need to continue monitoring the knowledge and technical capacity of health personnel critical to implementation of IDSR. With improving surveillance performance in the country, it is also necessary to put attention to the capacity of clinicians to more fully understand and execute their roles in respect to disease detection, confirmation, reporting and management. High volume health facilities are at higher risk of receiving priority disease patients. It is therefore proposed to build capacity of health facility surveillance focal persons and clinicians working in major hospitals in IDSR. This will build more capacity for IDSR coordination as well as clinicians playing a more active role in disease detection and management.

IDSR Strategies:

-Provide IDSR training for districts or health facilities where previously trained IDSR focal person is no longer working; considering also that more than one person per health facility can be trained -Provide IDSR case definition trainings -Support IDSR data quality efforts including data quality audits and regular visitation in the field to ensure accurate data capture -Conduct data analysis in health facilities for both IDSR/CBS data during the monthly in-charges meetings -Develop a tool for health facilities to better track/understand the Epi week number and dates -Expand trainings in high volume health facilities to include additional IDSR focal personnel from various wards -Provide supportive supervision for both IDSR and CBS (combined supervision is ideal) -Conduct data comparisons between IDSR and CBS to evaluate how CBS is enhancing the IDSR reporting system -Develop and deploy evaluation tools for CBS -Support CBS monthly community level meetings to support CHWs and their supervisors on community engagement and on-going support for trigger identification and reporting -Support CBS community sensitization with local leaders

Infection Prevention and Control (IPC) The growing number of emerging infectious diseases requires increased awareness and attention to IPC. There is therefore need to strengthen the MOHS through the National IPC unit to build stronger sustainable IPC teams and systems at district and facility level. IPC is cross cutting and should be integrated in all levels of health delivery. In order to improve quality of care there is need to provide HCWs with adequate training, knowledge, tools of the trade and a safer working environment. While the burden of HAI or AMR is unknown in Sierra Leone surveillance of HAI whether in patients or among health workers does not exist. This therefore necessitates the development and strengthening of HAI and AMR surveillance systems and occupational safety in Sierra Leone. Health care workers (HCWs) are at risk of various occupational hazards in the hospital, including exposure to blood borne infections such as HIV and hepatitis B and C virus from sharps injuries and contact with body fluids.

IPC Strategies:

-Strengthen capacity of the National IPC Unit to effectively implement IPC guidelines and policy in Health Care Facilities -Support National IPC Program by Building Human Resources Capacities -Support Establishment of Health Worker Safety Program -Support HAI surveillance and Antibiotic Stewardship in 4 Regional Hospitals -Strengthen Screening and Isolation Procedures

Laboratory Sierra Leone still experiences gaps in its laboratory capacity, mainly resulting from inadequate laboratory facilities, poor networking, inadequate numbers of technical personnel as well as lack of equipment and other supplies. Medical and public health laboratory services are a critical component of national health systems, central to disease diagnosis, treatment, prevention, and surveillance and outbreak investigations. When used optimally, laboratory testing generates knowledge that can facilitate patient safety, improve patient outcomes and lead to more cost-effective healthcare. Without an effective laboratory service, patient diagnosis and care is often compromised, expensive drug treatments are squandered, diagnoses are missed and information about public health is inaccurate. It is also impossible to measure the true effectiveness of interventions and to conduct accurate disease surveillance. Thus, strengthening laboratory capacity to meet the demands of surveillance and medical practice is fundamental to achieving a functional health system. A tiered, integrated laboratory network with strong supporting core capabilities and infrastructure in a number of important areas will provide the best model for efficient service delivery across various levels of the public health system. Strengthen Specimen Management & Referral at the Regional Laboratories

Laboratory Strategies:

-Strengthen Laboratory Information and Management System (LIMS) at Regional Labs -Strengthen Regional Lab Diagnostic Capacity -Strengthen Laboratory Management and Coordination at Regional Labs Sierra Leone

Status of Monkeypox epidemiology, surveillance, medical countermeasures
The immediate goal will be to assemble a meeting in Geneva, likely in connection with the Advisory Committee on Variola Virus research, to discuss progress on and coordination of monkeypox disease surveillance and response activities in West and Central Africa. Regional approaches to augmenting disease prevention and control will be discussed, as well as updates on medical countermeasures which may be useful for disease control work.

WHO POC: Asheena Khalakdina

HQ

Lab activities in Pakistan through WHO EMRO
WHO Regional Office for Eastern Mediterranean, has conducted several Laboratory Assessments in the Region and during May 2016 conducted the JEE in Pakistan along with CDC and other partners to identify gaps in IHR capacities.

The most common gaps were identified due to LQMS/BRM. Through these analyses several countries including Pakistan were identified by the WHO-EMRO PHL unit, leading to prioritization of activities to strengthen capacities like: Laboratory Quality Management including External Quality Assurance Scheme (EQAS) and BRM (safe working environment); provision of training, and PPE; monitoring and evaluation; etc.

The purpose of this project would be to critically address these gaps identified in laboratories with the aim of improving preparedness and operational readiness to prevent, detect, and respond to infectious diseases of public health importance. In addition WHO would continue to support a full time Laboratory Coordinator/Resident Advisor position who would spend majority of the time on Pakistan Laboratory systems strengthening activities working closely with the Pakistan National Institute of Health Public Health Labs Division.

EMRO

Rapid scale up of laboratory capacity for Vaccine Preventible Diseases ( VPDs, Viral) including Rapid Diagnostic Tests (RDTs)
Laboratory systems will be enhanced in 4 GHS countries for viral VPDs both at the National Public Health Laboratories (NPHL) and Regional Reference Laboratories (RRL). Rapid Response Teams will be trained for use of measles RDTs and RDTs will be pre-positioned for ready deployment during outbreaks. This will be a quick win, since (1) plan is to scale up existing WHO LabNet systems (2) mechanisms in place (3) measles and polio are GHS priority pathogens (4) sustainable model since the work will be done in collboration with WHO.

Activities to include: 1. One training workshop for RDTs and procurement and pre-positioning of RDTs. 2.NPHL and RRLs enrolled in EQAS 3. One Training of Trainer workshop per country for specimen collection and transport including a one time donation of specimen collection materials.

Countries for implementation: Cote D' Ivoire, Ghana, Cameroon, Uganda Multiple

Liberia MOH support
Project objectives should focus on providing technical support to the Liberia Ministry of Health (MOH) County Health Teams, partners, and stakeholders through County Epidemiologist positions during an estimated six month period to strengthen detection and screening capacities for EVD survivors; increase detection and screening capacities for priority health conditions across Liberia; and increase public health capacities to detect, investigate, respond to, and manage public health events of international concern (PHEIC). EVD detection and screening improvement activities should include:

• Coordination of stakeholders and partners providing Ebola Virus Disease (EVD) screening, care, and counseling;

• Planning and coordination for Men’s Health Screening Program monitoring and strengthening of collaboration with EVD survivor research programs;

• Improvement of EVD survivor counseling, screening, and care guidelines and protocol; and

• Healthcare worker mentoring and training to improve EVD survivor counseling, screening, and care services.

Activities focusing on PHEIC detection, investigation, and response should include:

• Providing technical support to the MOH in coordinating national surveillance review meetings with key stakeholders;

• Regular review and updates of IDSR-event based surveillance operational plans, national guidelines, Standard Operating Procedures (SOPs), and capacity-building packages;

• Planning and implementation of simulation exercises and supportive supervision for health workers involved in PHEIC activities and healthcare worker refresher trainings.

Early detection and screening of priority health conditions in Liberia activities should include:

• Building frontline health worker capacities through trainings, mentoring, and supportive supervision in risk communication, IDSR and events-based surveillance, laboratory, and response and preparedness;

• Implementation of simulation exercises with non-health sectors, county partners, and civil society representatives;

• Implementation of refresher trainings at county, district, and health facility levels; and

• Conducting monthly program monitoring meetings and quarterly program reviews.

Liberia

Strengthening National Laboratory Systems
These should include guidance and tools for laboratory preparedness to meet public health emergencies under IHR/GHSA. They should support tiered laboratory services, laboratory workforce development, regulatory and legal framework, quality management, and biosafety /biosecurity measures necessary as a foundation for national laboratory systems. We are particularly interested in informed advocacy for national strategic planning for laboratories and leadership development for decision makers.
Multiple
Support WHO for Joint External Evaluation
Continued supporting and conducting country Joint External Evaluation (JEE) missions across the different WHO regions, and ensure the standardization of process and quality of results. Activities include the measurement of country specific capacity and progress in achieving GHS targets, and the implementation of findings and recommendations for further strengthening and maintaining the IHR core capacities for global health security. Priority should be given to regional and national-level support to JEE implementation and incorporation of post-JEE planning and resulting programs into standard processes. Solicitation amount reflects an upper limit and actual funding will depend on region/country need and remaining resources from prior JEE support.
Multiple
Building and Strengthening International Health Regulations (IHR) Core Capacities in Kenya
This proposal will focus on the work of WHO Kenya office to scale up IHR capacity, with the aim to improve core capacities within the context of preparedness and response. The proposal will focus on 2 key priority areas of international health regulations following findings of the 2017 JEE, while aligning to comparative advantages of WHO core functions.

1. IHR Coordination, Communication and Advocacy Proposed activities to promote multisectoral and multidisciplinary coordination:

• Facilitate coordination meetings and workshops to establish National Focal Point structures

• Support implementation of National Public Health Institute

• Provide guidance and assistance for the establishment of the required authorities for EOC

2. Operationalization of the Emergency Operations Center (EOC) Proposed activities to strengthen capacity and ensure sustainability:

• Support Simulation Exercises and missions

• Engage Technical Officer for EOC support

• Finalize development of SOPs, including Risk Communication SOPs

• Develop outbreak investigation response database Kenya

Proposed Objectives and Activities:

A. List proposed objectives for the Round 5 proposals. These objectives must support the intent of the original Funding Opportunity Announcement (FOA) or Program Announcement (PA).

B. Each objective and activity must contain a performance or outcome measure that assesses the effectiveness of the project.

C. For each objective:

1. List activities that will be implemented;

2. Provide a timeline for accomplishment;

3. Identify and justify any redirection of activities; and

4. Explain the methods you will use to implement the new, redirected activities.

D. In addition to this information, include comments pertaining to budgetary issues that might hamper the success or completion of the project as originally proposed and approved. Please utilize the work plan format in the original work plan, if applicable.

5. Additional Program Requirements (If applicable)

Program should include guidance for any additional requirements of the recipient for the upcoming budget period. Changes in programmatic priorities must be within the scope of the approved funding opportunity announcement and Notice of Award.

Performance Measure Reporting: CDC programs must require awardees to submit performance measures annually as a minimum, and may require reporting more frequently. Performance measure reporting must be limited to data collection. When funding is awarded initially, CDC programs must specify required reporting frequency, data fields, and format.

Rev. 4/28/15 image1.tiff

File details come from the government source that posted it.