BITSDIS_2_RFI_1.pdf

REQUEST FOR INFORMATION/SOURCES SOUGHT NOTICE

National Institutes of Health (NIH), National Cancer Institute (NCI), Center for Biomedical Informatics and Information Technology (CBIIT) Biomedical Information Technology, Software Development, and Informatics Support

(BITSDIS-2)

INTRODUCTION

The U.S. Department of the Interior (DOI), Acquisition Services Directorate (AQD), on behalf of the National Institutes of Health (NIH), National Cancer Institute (NCI), Center for Biomedical Informatics and Information Technology (CBIIT) is seeking information for market research purposes to determine the availability of qualified businesses to provide professional biomedical informatics, data science, information technology, software development, and artificial intelligence support services for the NCI and more broadly the NIH and its support of integrated Information Technology (IT) and biomedical informatics coordination and management efforts.

This Request for Information (RFI)/Sources Sought Notice (SSN) is for market research purposes only. The information from this market research will assist the Government with acquisition planning.

BACKGROUND

The NIH’s mission is to seek fundamental knowledge about the nature and behavior of living systems and to apply that knowledge to enhance health, lengthen life, and reduce illness and disability. The NCI is one of the 27 institutes that make up the NIH, the nation’s primary federal agency for biomedical and public health research. that conducts and supports research, training, and health information dissemination with respect to the cause, prevention, diagnosis, and treatment of cancer, rehabilitation from cancer, and the continuing care of cancer patients and the families of cancer patients..

The CBIIT is an important NCI component entrusted to lead and coordinate efforts in the fields of informatics, data science, and information technology. CBIIT is defining, designing, developing, and deploying key infrastructure, standards, and application-level components of the Information Technology (IT) fabric to support a modern vision for integrated cancer and biomedical research, translational and population science, and personalized medicine. CBIIT establishes and develops the framework, infrastructure, standards, processes, and tools for data collection and management to ensure the long-term value of NCI’s investment in research through data accessibility, interoperability, sharing, and reuse. CBIIT creates mechanisms to build and support information networks enabling all constituencies in the cancer community – NCI programs, other institutions, researchers, physicians, and patients – to facilitate new discovery, integrate data, implement knowledge, make research results available for the community, minimize the burden of cancer, and improve the lives of patients.

Major ongoing NCI initiatives and programs supported under this Statement of Work (SOW) include, but are not limited to, the Cancer Research Data Commons (CRDC), and a comprehensive Clinical Reporting and Research Informatics (CRRI) initiative that include elements of the Cancer Moonshot and Precision Medicine Initiative (PMI). CRRI will include Precision Medicine Activities (PMA), Correlative Study Management (CSMS), the Clinical

Trials Reporting Program (CTRP) and CTRP’s Clinical Trials Reporting Office (CTRO), as well as Computational Genomics and Bioinformatics research and ancillary support services.

BUSINESS NEED

The objective of this requirement is to acquire contractor services that provide and deliver results-oriented solutions to enhance biomedical informatics programs across the NIH, including support to the NCI and more specifically CBIIT. The contractor services shall support strengthening the Office of the Chief Information Officer (OCIO)’s ability to effectively manage, analyze, process, and share biomedical data in accordance with NIH/HHS policies, applicable federal regulations, and scientific best practices.

Reference Attachment 1 – BITSDIS 2 SOW_RFI Draft for additional details pertaining to this requirement.

PURPOSE

This RFI is seeking responses from businesses to address the questions outlined in the Section titled “Information Requested.” The Government is looking for qualified contractor sources to provide the services and tasks contained in the attached draft Statement of Work via a multiple-award IDIQ contract.

INFORMATION REQUESTED

Provide a written response for the following questions:

1. Provide the name, telephone number, mailing address, unique entity identifier (UEI), and email address of a point of contact having authority and knowledge to discuss responses with Government representatives.

2. Identify if your company is one or more of the following small business types: small, business (SB), 8(a) participant, women-owned small business (WOSB) concern, economically disadvantaged women-owned small business (EDWOSB) concern, HUBZone small business concern, or service-disabled veteran-owned small business (SDVOSB) based on the NAICS identified herein.

3. The Government has identified the North American Industry Classification System (NAICS) Code(s) of 541690, “Other Scientific and Technical Consulting Services” for this requirement with a size standard of $19 Million. Please identify any other applicable NAICS codes to this requirement.

4. Identify and describe your prior experience staffing and maintaining a capable workforce on projects of this size and scope. The Government estimates that the scope of work of concurrent Task Orders could require a level of effort equivalent to 150 – 200 FTE.

5. Discuss how you deal with knowledge transfer and communications with outgoing and incoming contractors and individual contract support staff.

6. Identify any technical, programmatic, security/ATO, and data governance risks you foresee in executing these requirements. Define risk reduction measures you would employ to address these risks.

7. Describe how you have worked in a multiple contractor environment and dealt with relationships, communication, and project management across multiple contracts.

8. Identify how you have implemented a successful process for communicating and working with healthcare, scientific, research, or medical stakeholders in each of the applicable task areas in the SOW and working with other contractors.

9. Identify any potential conflicts of interest that may arise in the future. Please identify any suggested measures to mitigate the potential for Organizational Conflict of Interest

(OCI).

10. Identify any information you feel is missing in the draft SOW that would be beneficial to accurately define and develop your technical solution, staffing model, and costs.

11. Identify any commercial off-the-shelf (COTS) products, platforms, or tools your company would propose to leverage in performing this work. For each, briefly describe how it would be applied to this requirement and any relevant compliance certifications (e.g., FedRAMP authorization).

Provide a completed matrix (Attachment 2 – BITSDIS 2 Matrix) for the following:

12. Past Performance: Provide no more than three past performance references from within the past three years providing services satisfying the government’s requirements in the SOW in a Federal Health organization of similar size (over 3,500 employees and collaborators), similar budget (~$6B), and complexity as NCI (Supports multiple Federal and National distributed teams, supporting multiple integrated federal and academic organizations, performing clinical and translational research, and defining data exchange standards in support of conducting next generation clinical trials).

In Tab 1 of the excel spreadsheet, provide the below:

a) Client

b) Title of Project

c) Contract Type

d) Contact Number

e) Contract Value

f) Period of Performance

g) Cloud environment, security posture (ATO/FISMA)

h) Major deliverables/outcomes/additional comments

13. Capabilities: In Tab 2 of the excel spreadsheet list your capabilities in performing the task areas listed in Attachment 1 – BITSDIS 2 SOW_RFI Draft. Identify if you will prime, sub, or team to provide the listed services.

INSTRUCTIONS FOR SUBMISSION

Firms with the capability to provide the requirements referenced herein are invited to submit, in writing, information in accordance with the instructions below. This information should be responsive to the request for information identified above as well as any technical questions, as indicated herein. Submissions for the information must be organized and identifiable per the information in this RFI, e.g. responses to questions are numbered by question and follow the same sequence.

Written responses are limited to ten (10) pages or less. Submissions should be in a Microsoft Office compatible format (i.e., Microsoft Word, PowerPoint, Excel, etc.) or Adobe Acrobat.

A page is defined as an 8.5 inch by 11 inch sheet of paper with no less than one-inch margins on all four sides; All pages shall be single-spaced, single-sided, with a font no less than 10 points for text, tables, and graphics; Spacing before and after the line shall be no less than 3 point; the following page types do NOT count towards the page limitations:

• Section dividers

• Blank pages, which must be marked “This page intentionally left blank”

• Fold-outs shall be counted as the appropriate number of pages based upon an 8.5 inch by

11 inch sheet of paper; partial pages shall be rounded up (e.g., 1.5 pages will be treated as 2 pages.);

Responses are due no later than 10:00 AM ET, May 5, 2026. Submissions shall be submitted via email to Russell Pfeiffer at Russell_pfeiffer@ibc.doi.gov and Victoria Seelhoefer at Victoria_seelhoefer@ibc.doi.gov. Paper copies will not be accepted. The responses must include the business size of the vendor under NAICS code 541690 including any applicable small business subcategory (Service Disabled-Veteran Owned Small Business, Veteran-Owned Small Business, Women-Owned Small Business, HUBZone Small Business, Small Disadvantaged Small Business, Small Business Joint Venture, Consortium, Team Partnering, or Other than Small Business). Offerors should indicate if they would need to subcontract and, if so, for which tasks.

ADDITIONAL INFORMATION

This RFI is being issued solely for market research information and acquisition planning purposes. It does not constitute a Request for Proposal (RFP) or a promise to issue an RFP in the future. This RFI does not commit the Government to a contract for any supply or service whatsoever. Furthermore, the Government is not at this time seeking proposals and will not accept unsolicited proposals. Responders are advised that the Government will not reimburse for any information or administrative costs incurred in response to this RFI; all costs associated with responding to this RFI will be solely at the interested parties’ expense. Not responding to this RFI does not preclude participation in a future RFP, if one is issued. However, interested parties are encouraged to participate in this RFI.

Proprietary information and trade secrets, if any, must be clearly marked on all materials. All information received that is marked Proprietary will be handled accordingly. Please be advised that all submissions become Government property and will not be returned. All Government and mailto:Russell_pfeiffer@ibc.doi.gov mailto:Victoria_seelhoefer@ibc.doi.gov contractor personnel reviewing RFI responses will have signed non-disclosure agreements and understand their responsibility for proper use and protection from unauthorized disclosure of proprietary information as described in 41 U.S.C. 423. The Government shall not be held liable for any damages incurred if proprietary information is not properly identified.

No telephone calls or emails will be accepted requesting additional information regarding an RFP or solicitation for this requirement. There is no RFP or solicitation. In order to protect the procurement integrity of any future procurement, if any, that may arise from this announcement, information regarding technical point of contact will not be given and no appointments for presentations will be made.