B Sources Sought Notice - Milipore.docx

SOURCES SOUGHT NOTICE

1. Solicitation Number: 75N9502300202

2. Title: Milli-Q® IQ 7003 Water Purification System

3. Classification Code: N046 - Installation of Equipment- Water Purification and Sewage Treatment Equipment

4. NAICS Code: 221310 - Water Supply and Irrigation Systems

5. Size Standard: $41 M

6. Description:

This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement.

This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement, to determine the method of acquisition, and availability of domestic sources manufactured in the United States in sufficient and reasonably available commercial quantities and of a satisfactory quality. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Small businesses are encouraged to respond.

For equipment/supply requirements, responses must include the place of manufacturing (i.e. address if supply/equipment is a domestic end product and include country of manufacture). For equipment/supply requirements, small businesses must also address the size status of the manufacturer under the applicable NAICS code (i.e. address Non-Manufacturer Rule).

Background: The National Institutes of Health (NIH) is an agency of the Department of Health and Human Services and the Federal focal point for health research. Its mission is to seek fundamental knowledge about the nature and behavior of living systems and apply that knowledge to enhance health, lengthen life, and reduce illness and disability.

The National Institute of Neurological Disorders and Stroke (NINDS), which is an Institute within the NIH, seeks to reduce the burden of neurological disease through supporting and conducting basic, translational, and clinical research on the healthy and diseased nervous system, fostering the training of investigators in the basic and clinical neurosciences, and seeking better understanding, diagnosis, treatment, and prevention of neurological disorders.

Purpose and Objectives: The synaptic communication between the millions of neurons in the human brain is what allows it to function normally. Understanding the chemical basis of synaptic transmission under normal and abnormal circumstances is the aim of NINDS’ Synaptic Transmission Section, which investigates the molecular mechanisms underlying SNARE complex formation and interaction in cultured neurons from the hippocampus and adrenal medulla. This section’s research could help in the diagnosis and treatment of prevalent neurological conditions like Alzheimer's disease.

The fields of synaptic transmission and exocytosis research will both benefit from a quality ultrapure water source. A high-quality and reliable ultrapure water source is crucial for NINDS’ research as without it cell culture, molecular, and biochemistry experiments would be impossible to perform.

Project requirements:

· Must have the ability to produce Type I ultrapure water.

· Must provide easy Volumetric Water Dispensing, with ultrapure water flow rates adjustable from drop-by-drop to 2 L/min.

· Complete process monitoring system systematically must check water temperature, pressure, and conductivity, using calibrated meters at different steps.

· The ultrapure water system must be able to recirculate water to maintain high water quality during periods of non-use.

· Must be able to select a Unique Range of Final Polishers, to adapt to specific application(s). Millipak (bacteria removal), Biopak (to remove RNAse, DNAse, and Pyrogens), LC Pak for production of UHPLC or LC-MS grade water.

· To avoid maintenance errors and to improve traceability, the internal primary consumable water purification cartridges must have a built-in RFID tag

· Must include 5” capacitive touch screen interface that allows easy interaction with system and provides pertinent data, including step-by-step graphical maintenance protocols.

· Must include low voltage DC pump (<50 decibels at 1m) for virtually silent operation

· The ability to accurate Temperature Measurement of +/- 0.1 degrees Celsius to improve the precision of Temperature Compensation at 25 degrees C

· Must include extensive service software program thereby providing all pertinent service information

· The system must have built-in mercury-free, Xenon eximer UV lamps with a two-year life time, emission at 172 nm and 265 nm wavelengths for oxidation and bactericidal functions.

· The ability to purify water in a first step using unique Jetpore ion-exchange resin, synthetic activated carbon, and UV lamp at 185 nm to reach a resistivity of 18.2 MΏ.cm at 25◦C and a TOC value <5ppb. Monitored by advance analytical techniques.

· The ability for the system to give a TOC result from an A10 TOC monitor that is calibrated to international norms and standards.

Anticipated period of performance: N/A

Other important considerations: N/A

In case domestic sources are available and capable of fulfilling the Government’s need, and a future solicitation is published, the Government will use evaluation preferences in accordance with FAR 25.

Capability statement /information sought.

Companies that believe they possess the capabilities to provide the required product should submit documentation of their ability to meet each of the project requirements to the Contracting Officer. The capability statement must specifically address each of the project requirements separately. Additionally, the capability statement should include 1) the total number of employees, 2) the professional qualifications of personnel as it relates to the requirements outlined, 3) any contractor GSA Schedule contracts and/or other government-wide acquisition contracts (GWACs) by which all of the requirements may be met, if applicable, and 4) any other information considered relevant to this program. Capability statements must also include the Company Name, Unique Entity ID from SAM.gov, Physical Address, and Point of Contact Information. The response must include the respondents’ technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses.

Interested companies are required to identify their type of business, applicable North American Industry Classification System (NAICS) Code, and size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the solicitation notice number.

One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2” x 11” paper size, with 1” top, bottom, left and right margins, and with single or double spacing.

The information submitted must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein. A cover page and an executive summary may be included but is not required.

The response is limited to ten (10) page limit. The 10-page limit does not include the cover page, executive summary, or references, if requested.

All responses to this notice must be submitted electronically to the Contract Specialist and Contracting Officer. Facsimile responses are NOT accepted.

The response must be submitted to Shivani Patel, Contracts Specialist at e-mail address Shivani.patel@nih.gov

The response must be received on or before 4/18/2023, 3:00 pm Eastern Time.

“Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s qualifications to perform the work.

Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in www.sam.gov. However, responses to this notice will not be considered adequate responses to a solicitation.

Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).”