Attachment 3 CLINS_Pricing Sheet.xlsx
XLSX spreadsheet 455 KB Posted
- Attached to
- Pre-Trial Testing for Alzheimer's Drug
- Solicitation number
- 36C24E25Q0056
About this file
The file "Attachment 3 CLINS_Pricing Sheet.xlsx" appears to be a pricing document related to a Veterans Affairs solicitation for pre-trial testing of an Alzheimer's drug. The solicitation (RFQ 36C24E25Q0056) is an unrestricted competition for testing laboratory services under NAICS code 541380, with a business size standard of $19.0 million. The contract is for IND Testing of an Alzheimer's drug, with a period of performance from 9/28/2025 to 9/27/2027, to be awarded by the Department of Veterans Affairs Veterans Health Administration.
Key submission requirements include mandatory SAM registration, written questions to be submitted to Renee Kale (renee.kale@va.gov) by 7 August 2025 at 10am, and adherence to specific quote submission instructions. The solicitation will result in a Standard Form 1449 award, and offerors are advised to carefully review the Statement of Work (Attachment 1) and submission guidelines (Attachment 2). The specific pricing details would be found in the referenced Excel spreadsheet, which was not fully provided in the document.
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Other files
| File | Type | Posted |
|---|---|---|
| 36C24E25Q0056 0001.docx | DOCX document | |
| Attachment 1 Statement of Work_Drug Chemistry Test 7-16-2025.docx | DOCX document | |
| Attachment 2 36C24E25Q0056.docx | DOCX document |
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Action Line Item Information
| Action Type Name | Primary ID | Secondary ID | Mod Number | Title | Order Discount Type Name | Order Discount Type | Order Discount |
| RFQ | 36C24E25Q0056 | Research Lab Services - Pre-Trial Testing for Alzheimer's Drug - MINN | EDA: 9/19/25 | Percent | 0 |
KB Version: FY25.08A
Items
| ITEM NUMBER | SLIN | DESCRIPTION | REF CLIN | COMMENT | INCLUDE COMMENTS IN DOCUMENT | CONTRACT PERIOD | POP BEGIN | POP END | QUANTITY | UNIT OF MEASURE | PACKAGING MULTIPLE | RECEIPT TYPE | LINE ITEM IS | UNIT PRICE | ITEM DISCOUNT TYPE NAME | ITEM DISCOUNT | DATE UPDATED | ADDRESS1 | ADDRESS2 | ADDRESS3 | CITY | STATE | ZIP | ZIP4 | COUNTRY | MARK FRO | CONTACT NAME | CONTACT PHONE | CONTACT EMAIL | DDELIVERY DATE | FOB | SPECIAL INSTRUCTIONS | INCLUDE INSTRUCTIONS/COMMENTS IN DOCUMENT | INCLUDE DATA VALUES IN DOCUMENT | PRINCIPAL NAICS CODE | PRODUCT/SERVICE CODE | UNSPSC | SIC CODE | MANUFACTURER PART NUMBER (MPN) | NATIONAL STOCK NUMBER | LOCAL STOCK NUMBER | DM DOC ID | DELIVERY REF. COUNTER | UNIT TEXT/DESCRIPTION | DELIVERY REFERENCE | ITEM MASTER FILE NUMBER | EXPENDABLE/NON-EXPENDABLE | QUANTITY REQUESTED | UNIT OF PURCHASE CODE |
| 0001 | Phase 1 Task 1: Work Plan | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0002 | Phase 1 Task 2: Test artcile solubility testing-TA1 | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0003 | Phase 1 Task 3: Coctail IC50 Determinations-TA1 | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0004 | Phase 1 Task 4: Test article solubility testing-TA2 | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0005 | Phase 1 Task 5: Cocktail IC50 Determinations-TA2 | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0006 | Phase 2.1 Task 1: In vitro evaluation of test article as an inhibitor of human cyp enxymes workplan | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0007 | Phase 2.1 Task 2: Test artcile solubility testing | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0008 | Phase 2.1 Task 3: IC50 determinations | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0009 | Phase 2.2 Task 1: In vitro evaluation of induction of human CYP enzymes by a test article work plan | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0010 | Phase 2.2 Task 2: Test artcile solubility testings | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0011 | Phase 2.2 Task 3: Human hepatocyte culture (CYP1A2, 2B6, 3A4 mRNA experiment) | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0012 | Phase 2.2 Task 4: mRNA analysis by qRT-PCR | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0013 | Phase 2.2 Task 5: Cytoxicity testing concurrent with main assay | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0014 | Phase 2.2 Task 6: LC-MS/MS Method development | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0015 | Phase 2.2 Task 5: Spent media analysis (TA stability in test system) | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0016 | Phase 2.3 Task 1: Invitro human CYP reaction phenotyping of a test article work plan | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0017 | Phase 2.3 Task 2: Test article solubility testing | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0018 | Phase 2.3 Task 3: LC-MS/MS development | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0019 | Phase 2.3 Task 4: LC-MS/MS method qualification | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0020 | Phase 2.3 Task 5: Preliminary human liver microsome assay | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0021 | Phase 2.3 Task 6: Recombinant CYP emzyme assay | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0022 | Phase 2.3 Task 7: Chemical inhibition assay in human liver microsomes | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0023 | Phase 2.4 Task 1: Plasma protein binding assessment of test artcile using rapid equilibrium dialysis workplan | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0024 | Phase 2.4 Task 2: Test artcile solubility testing | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0025 | Phase 2.4 Task 3: LC-MS/MS method development for TA | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0026 | Phase 2.4 Task 4: Preliminary experiments for plasma protein binding | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0027 | Phase 2.4 Task 5: Plasma protein binding determination | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0028 | Phase 2.5 Task 1: In vitro evaluation of a test article as an inhibitor and substrate of human transporters workplan | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0029 | Phase 2.5 Task 2: Test artcile solubility testing | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0030 | Phase 2.5 Task 3: LC-MS/MS method development | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0031 | Phase 2.5 Task 4: Preliminary experiments | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0032 | Phase 2.5 Task 5: Transwell ABC transporter IC50 determination | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0033 | Phase 2.5 Task 6: SLC transporter IC50 determination (FDA Guidance Panel) | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0034 | Phase 2.5 Task 7: ABC Transporter substrate determination (transwell assay) | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0035 | Phase 2.5 Task 8: Preliminary experiments for BSEP | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 | |||||||||||||||||||||||||||||||||||||||||
| 0036 | Phase 2.5 Task 9: Vesicle ABC percent inhibition determinations:BSEP | Base | 9/28/25 | 9/27/27 | 1 | JB | Priced | $0.00 |
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