Attachment 1 - Statement of Work.pdf

STATEMENT OF WORK (SOW)

TITLE: SERVICE CONTRACT FOR LEICA IMAGING PLATFORMS FOR THE

LABORATORY OF IMMUNE SYSTEM BIOLOGY (LISB)

April 10, 2025

1.0 INTRODUCTION/OVERVIEW

The U.S. Department of Health and Human Services (HHS), National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID) conducts and supports applied research to better understand, treat and ultimately prevent infectious, immunologic, and allergic diseases. NIAID has a unique mandate, which requires the Institute to respond to emerging public health threats. One of the major program areas within NIAID is the Division of Intramural Research (DIR). DIR’s mission is to make scientific discoveries that promote the development of new vaccines, diagnostics, and therapeutics that improve human health. DIR’s research goals encompass expanding knowledge of normal immune system components and functions, defining mechanisms responsible for abnormal immune function (immunodeficiency, allergy, and autoimmunity), understanding the biology of infectious agents (viruses, bacteria, fungi, and parasites) and the host response to infection, as well as developing strategies to prevent and treat immunologic, allergic, and infectious diseases.

2.0 BACKGROUND INFORMATION

Of the 16 laboratories in DIR, the Laboratory of Immune System Biology (LISB) conducts research in fundamental and applied aspects of immunology. The major research activities of LISB are focused on the basic genetics, molecular biology, and cell biology of the immune system, as well as on human diseases informed by these more basic studies. A key aspect of LISB’s research is the development and application of systems and quantitative approaches to dissect how the molecules, cells, and commensals studied by LISB investigators together shape emergent immune system behavior. To do so, LISB along with the Center for Advanced Tissue Imaging (CAT-I) focus on high-tech imaging analysis and advanced microscopy techniques.

LISB has multiple high-end platforms already in use for imaging various samples and therefore, a service contract is needed for various equipment to augment those capabilities by providing support upstream of imaging and servicing. Since they are so widely used, services described in this SOW are needed for LISB’s microscopy equipment to ensure the optimal condition of and successful continuous operation of instruments without failure. Without a service contract that includes a preventive maintenance visit and prompt service to remedy downtime, there would be detrimental impacts to the research work of LISB’s investigators.

3.0 OBJECTIVE

The objective of this SOW is to procure a base plus four (4) option periods contract for maintenance services for 14 instruments manufactured by Leica Microsystems that include the SP8, SP8 DIVE, and Thunder microscopes that are used for high-tech imaging analysis and advanced microscopy techniques in CAT-I and LISB. These services are necessary to ensure the microscopy and imaging equipment are in optimal condition to ensure the successful, continuous operation of the instrumentation without failure as the instruments are widely used by investigators. The instrument models consist of the following:

Equipment No. Serial No. Description

11367646 8100000263 SP8 AOBS IR 81-263

12458257 8110002284 SP8 WLL2 TAN 811-2284

12114243 8100001644 SP8WLL2 SMD 81-1644

12114242 8100001645 SP8WLL2 SMD 81-1645

12800275 516756 THUNDER 516756

12660478 501004 THUNDER 501004

12914688 8300000272 STELLARIS 8- 83-272

12914688 8300000272 STELLARIS 405 PQ

12914688 8300000272 WLL STELLARIS 8 PP

12916377 8300000271 STELLARIS 83-271

12916377 8300000271 STELLARIS 488

12916377 8300000271 STELLARIS 561

12916377 8300000271 STELLARIS 638

12916377 8300000271 WLL STELLARIS 83-271

4.0 SCOPE

The scope of this effort includes the resources necessary to perform preventative, remedial maintenance and repair services to maintain the equipment above in optimal operating condition in accordance with the equipment manufacturer’s specifications.

5.0 CONTRACTOR REQUIREMENTS

The Contractor shall provide a service agreement plan for the lab equipment that includes minimal downtime through responsive onsite service and preventative maintenance by factory trained field service engineers. The key features of this service plan shall include:

• Unlimited service visits by Leica trained and certified field service engineers.

• Unlimited original equipment manufacturer (OEM)’s replacement parts, components, or modules necessary for repairs, excluding multiphoton lasers, third party items, and consumables. Coverage of OEM parts, labor, and travel. Coverage includes all fees associated with repairs (labor and replacement parts) for any service or repairs performed.

• One (1) onsite Preventive Maintenance inspection to be performed during each period of the base plus 4 option periods contract to ensure the instruments are performing to factory specifications.

• Priority scheduling and onsite response for all repairs during the period of performance.

Priority is defined as giving priority scheduling equal to a direct contract and guaranteeing the equivalent manufacturer’s priority onsite response. If you are a third-party service provider, the priority scheduling and/or response time must be listed in your quotation. OEM Trained Certified Technicians required.

• 24-hour guaranteed priority response time after receipt of a service call.

• Proprietary instrument control software and hardware updates (can occur during schedule firmware updates upon request, and in conjunction with a scheduled Preventive

Maintenance or Corrective Maintenance visit), including software revision. Provide End User License Agreement (EULA) if applicable.

• Unlimited service visits and telephone support during normal business days and hours, excluding Federal holidays, as well as access to expert applications and technology support center (M-F, 8 AM – 5 PM EST).

• Field service representative trained to provide service in biosafety level 2 (BSL-2).

6.0 CONTRACTOR SUPPLIED MATERIALS

The Contractor shall provide all necessary parts and equipment necessary to perform remedial repair and planned maintenance of the above equipment.

7.0 GOVERNMENT FURNISHED MATERIALS

No Government furnished materials are provided under the contract.

8.0 REPORTING REQUIREMENTS AND DELIVERABLES

Technical support, remedial repair (as needed), one (1) annual planned preventive maintenance, and reporting document of service after PMs and repairs are completed.

9.0 PERIOD OF PERFORMANCE

The anticipated period of performance for the base plus 4 option periods contract is as follows:

Base Period: May 1, 2025 – March 31, 2026 Option Period 1: April 1, 2026 – March 31, 2027 Option Period 2: April 1, 2027 – March 31, 2028 Option Period 3: April 1, 2028 – March 31, 2029 Option Period 4: April 1, 2029 – March 31, 2030

10.0 PLACE OF PERFORMANCE

NIH/NIAID

4 Memorial Drive Bethesda, MD 20814

11.0 INSPECTION AND ACCEPTANCE

a) All work will be inspected and approved by the person designated by the lab chief of each lab at the completion of any repairs and at the completion of the annual maintenance.

b) All work will be completed in accordance with industry standards.