Attachment 1_Statement of Need.pdf

STATEMENT OF NEED (SON)

1.0 TITLE

Acquisition of eight (8) Brand Name or Equal Med Associates Social Self-Administration Chambers and accessories.

2.0 BACKGROUND

The Pain Neurocircuitry and Cellular Plasticity Laboratory (PNCPL), within the Division of Intramural Research (DIR) at the National Center for Complementary and Integrative Health (NCCIH), requires (8) Med Associates social self-administration chambers or equivalent, to study brain mechanisms at the intersection of pain and reward. One of PNCPL’s goals is to incorporate novel approaches to study brain mechanisms of pain-related affective comorbidities. The required equipment shall be used to evaluate anhedonia in rodents.

Specifically, lab members will measure the effects of pain on the motivation of mice to work (by pressing a lever) to receive rewards (palatable food, social interaction with a conspecific, and drugs), as well as underlying mechanisms.

3.0 TYPE OF ORDER

This is a Firm Fixed-Price Purchase Order.

4.0 SPECIAL ORDER REQUIREMENTS

The Contractor shall provide the following items or Equivalent:

Item Item Description Manufacturer Part # Quantity

1 Med Associates, Inc. Wide Social Self- Administration Chamber for mouse

ENV-307WCT-SOCIAL 8

2 Med Associates, Inc. Stainless Steel Grid Floor for Extra Wide Modular Test Chamber for Mouse

ENV-307W-GFW 8

3 Med Associates, Inc. Floor for Mouse Social Chamber

ENV-307W-GFW-SOC 8

4 Med Associates, Inc. Auto Door for ENV-

307WCT-SOCIAL

ENV-3015BD2-SOCIAL 8

5 Med Associates, Inc. SmartCtrl, 8 Input / 16 Output Package

DIG-716P2 8

6 Med Associates, Inc. Power Cable, 25' (7.6 m) SG-210CP-25 2 7 Med Associates, Inc. Power Cable, 8' (2.4 m) SG-210CP-8 6 8 Med Associates, Inc. Intel i5 16GB RAM, 1TB

HDD Windows 11 Pro 64bit loaded with Med- PC IV, SN:MSF6803, version 4.58.01

COM-106-NV 1

9 Med Associates, Inc. Sonalert Module with Volume Control for ENV-307W Wide Mouse Chamber; 2,900 Hz

ENV-323AW 8

10 Med Associates, Inc. Stimulus LED Light, 1" White Lens Mounted on Modular Panel

ENV-221M-LED 8

11 Med Associates, Inc. 1" RED LED STIMULUS LIGHTW/ RED housing and Red diffusor

ENV-221RD-LED 8

12 Med Associates, Inc. Stim Light Mod. Panel for 307W Chamber

FAB-ENV-221M-17 16

13 Med Associates, Inc. Retractable Ultra-Sensitive Lever Wide Mouse Modular Chamber

ENV-312-3W 8

14 Med Associates, Inc. Ultra-Sensitive Lever for the Wide Mouse Modular Chamber

ENV-310W 8

15 Med Associates, Inc. Med Single Speed Syringe pump

PHM-200 8

16 Med Associates, Inc. Instech Adj.Multi-Axis Lever Arm. Mouse

PHM-124A 8

17 Med Associates, Inc. 25 gauge Stainless Steel Swivel

PHM-124B 8

4.1 PRODUCT FEATURES/SALIENT CHARACTERISTICS

The following product features/characteristics are required for (8) Med Associates or Equivalent, social self-administration chambers. The equipment shall:

• Allow NCCIH staff to measure the effects of pain on the motivation of mice to work towards receiving rewards.

• Allow NCCIH staff the ability to assess which type of reward the mice choose if presented with options.

• Include a social chamber with an automatic door allowing for delivery of social interactions with conspecifics.

• Include a built-in waste pan with grid flooring, allowing for easy clean up.

• Include a device that allows for the delivery of adjustable volume control of a single-tone frequency sound cue that will allow the mice to learn to press a lever to obtain a specific reward.

• Include a single computer interface with software and video monitoring that allows for real-time automated analyses of all the experimental parameters needed, including Windows 11 MED-PC IV version CD-4.58.01, or equivalent, with modules allowing for data collection from outside the chamber while minimizing the disruption of test animals.

o The computer shall include a monitor with speakers o Equipment shall include appropriate power supply, cables and adapters needed to successfully connect everything together.

• Include stimulus light modular panels with LED lights to deliver light clues to mice allowing them to learn to press a lever to obtain a specific reward.

• Allow for the monitoring and recording of animals in light or dark cycles.

• Include a mounted multi-axis lever arm to keep the tether out of the animal’s reach while allowing unhindered motion of the swivel.

• Include multiple levers that the mice will learn to press to obtain specific rewards.

• Include a syringe pump to deliver and measure rewarding effects of specific rewards and drugs.

4.2 DELIVERY

The Contractor shall deliver the equipment and associated components within 30 calendar days from the date of award. The Contractor shall coordinate delivery and tracking information with the NCCIH Technical Point of Contact (TPOC). All shipping/handling (including FOB) and delivery/installation fees shall be included. NCCIH will not be responsible for any shipping charges not listed in the quotation. Installation services shall not be performed under this purchase order.

The Contractor shall deliver the required equipment at the following addresses:

NIH/NCCIH

35 Convent Drive Room 1E-422 Bethesda, MD 20892

Note: Access to the NIH campus is restricted. As such all-Contractor personnel or contractors chosen delivery couriers will be required to access campus via designated entrances where they are subject to security screening. Please refer to the NIH Security and Access site for more details: (www.nih.gov/about-nih/visitor-information/campus-access-security).

4.3 TRAINING

The Contractor shall provide remote set-up and training support upon request from the TPOC.

4.4 WARRANTY

In addition to the Implied warranty contained in FAR Clause 52.212-4, the Contractor is encouraged to provide express warranties. At a minimum, the Contractor shall provide a 12-month warranty from date of final installation on all equipment and associated items provided under, or as a part of this purchase order. The warranty shall include repair and or replacement of parts, including travel, labor, and materials, at no additional cost to the Government. The warranty shall not exclude or limit the Governments rights for an Implied warranty as established in the terms and conditions of clause 52.212-4.

http://www.nih.gov/about-nih/visitor-information/campus-access-security

5.0 PAYMENT

Payment shall be made in full upon delivery, inspection, training and acceptance by the Government. The following clause is applicable to all Purchase Orders, Task or Delivery Orders, and Blanket Purchase Agreement (BPA) Calls: Prompt Payment (Jan 2017) FAR 52.232-25.

Highlights of this clause and NIH implementation requirements follow:

I. Invoice Requirements A. An invoice is the Contractor's bill or written request for payment under the contract for supplies delivered or services performed. A proper invoice is an "Original" which must include the items listed in subdivisions 1 through 12, below, in addition to the requirements of FAR 32.9. If the invoice does not comply with these requirements, the Contractor will be notified of the defect within 7 days after the date the designated billing office received the invoice (3 days for meat, meat food products, or fish, and 5 days for perishable agricultural commodities, dairy products, edible fats, or oils) with a statement of the reasons why it is not a proper invoice. (See exceptions under II., below.) Untimely notification will be considered in the computation of any interest penalty owed the Contractor.

1. Vendor/Contractor: Name, Address, Point of Contact for the invoice (Name, title, telephone number, e-mail and mailing address of point of contact).

2. Remit-to address (Name and complete mailing address to send payment).

3. Remittance name must match exactly with name on original order/contract. If the Remittance name differs from the Legal Business Name, then both names must appear on the invoice.

4. Invoice date.

5. Unique invoice #s for all invoices per vendor regardless of site.

6. NBS document number formats must be included for awards created in the NBS: Contract Number; Purchase Order Number; Task or Delivery Order Number and Source Award Number (e.g., Indefinite Delivery Contract number; General Services Administration number);

or, BPA Call Number and BPA Parent Award Number.

7. Unique Entity Identifier (UEI) which is in the System for Award Management (SAM) and replaces the Dun & Bradstreet Data Universal Numbering System (DUNS) number.

8. Federal Taxpayer Identification Number (TIN). In those rare cases where a contractor does not have a UEI number or TIN, a Vendor Identification Number (VIN) must be referenced on the invoice.

The VIN is the number that appears after the contractor’s name on the face page of the award document.

9. Identify that payment is to be made using a three-way match.

10. Description of supplies/services that match the description on the award, by line billed.

11. Freight or delivery charge must be billed as shown on the award. If it is included in the item price do not bill it separately. If identified in the award as a separate line item, it must be billed separately.

12. Quantity, Unit of Measure, Unit Price, Extended Price of supplies delivered or services performed, as applicable, and that match the line items specified in the award.

NOTE: If your invoice must differ from the line items on the award, please contact the Contracting Officer before submitting the invoice. A modification to the order or contract may be needed before the invoice can be submitted and paid.

Shipping costs will be reimbursed only if authorized by the Contract/Purchase Order. If authorized, shipping costs must be itemized. Where shipping costs exceed $100, the invoice must be supported by a bill of lading or a paid carrier's receipt.

B. NIH is using a phased transition approach from the NIH Office of Financial Management (OFM) Electronic Invoice Submission instructions to the Department of Treasury’s Invoice Processing Platform (IPP). This award will transition to IPP in the future. It is the Contractor/Vendor’s responsibility to periodically check the OALM IPP website and be prepared to transition to IPP on the designated transition date.

Until the Contractor/Vendor has transitioned to IPP as specified on the OALM IPP website, the Contractor/Vendor must follow step-by-step instructions as stated in the NIH/OFM Electronic Invoicing Instructions for NIH Contractors/Vendors, which is included as an attachment and is on the website at https://oamp.od.nih.gov/DGS/DGS-workform-information/attachment-files Questions concerning the transition to IPP should be directed to NIH-IPPinvoicing@mail.nih.gov. Questions concerning this award should be directed to the NIH Contracting Officer.

If this award is a parent indefinite delivery award or a Blanket Purchase Agreement Set-Up, then HHSAR 352.232-71 applies to all task/delivery orders or Blanket Purchase Agreement calls issued under this award.

The Contractor shall submit a copy of the electronic invoice to the following NCCIH TPOC:

Name- TBD at Award Email Address- TBD at Award

For inquiries regarding the status of invoices, contact OFM Customer Service via email at ofm_customer_service@incontactemail.com or via phone at 301-496-6088. To send https://oalm.od.nih.gov/IPP https://oalm.od.nih.gov/IPP https://oalm.od.nih.gov/IPP https://oamp.od.nih.gov/DGS/DGS-workform-information/attachment-files https://oamp.od.nih.gov/DGS/DGS-workform-information/attachment-files https://oamp.od.nih.gov/DGS/DGS-workform-information/attachment-files https://oamp.od.nih.gov/DGS/DGS-workform-information/attachment-files mailto:NIH-IPPinvoicing@mail.nih.gov mailto:ofm_customer_service@incontactemail.com your inquiries via other available communication methods refer to the OFM Customer Service website at https://ofm.od.nih.gov/Pages/Customer-Service.aspx.

Note: The OFM Customer Service is open Eastern Standard Time Monday – Friday from 8:30 a.m. to 5:00 p.m. and is closed between 12:00 p.m. to 1:00 p.m.

II. Invoice Payment

A. Except as indicated in paragraph B., below, the due date for making invoice payments by the designated payment office shall be the later of the following two events:

1. The 30th day after the designated billing office has received a proper invoice.

2. The 30th day after Government acceptance of supplies delivered or services performed.

B. The due date for making invoice payments for meat and meat food products, perishable agricultural commodities, dairy products, and edible fats or oils, shall be in accordance with the Prompt Payment Act, as amended.

III. Interest Penalties

A. An interest penalty shall be paid automatically, if payment is not made by the due date and the conditions listed below are met, if applicable.

1. A proper invoice was received by the designated billing office.

2. A receiving report or other Government documentation authorizing payment was processed and there was no disagreement over quantity, quality, or contractor compliance with a term or condition.

3. In the case of a final invoice for any balance of funds due the contractor for supplies delivered or services performed, the amount was not subject to further settlement actions between the Government and the Contractor.

B. Determination of interest and penalties due will be made in accordance with the provisions of the Prompt Payment Act, as amended, the Contract Disputes Act, and regulations issued by the Office of Management and Budget.

IV. PROVIDING ACCELERATED PAYMENT TO SMALL BUSINESS SUBCONTRACTORS,

FAR 52.232-40 (March 2023)

(a) Upon receipt of accelerated payments from the Government, the Contractor shall make accelerated payments to its small business subcontractors under this contract, to the maximum extent practicable and prior to when such payment is otherwise required under the applicable contract or subcontract, after receipt of a https://ofm.od.nih.gov/Pages/Customer-Service.aspx proper invoice and all other required documentation from the small business subcontractor.

(b) The acceleration of payments under this clause does not provide any new rights under the Prompt Payment Act.

(c) Include the substance of this clause, including this paragraph (c), in all subcontracts with small business concerns, including subcontracts with small business concerns for the acquisition of commercial products or commercial services.

V. HHSAR 352.232-71 Electronic Submission of Payment Requests (February 2, 2022)

(a) Definitions. As used in this clause— Payment request means a bill, voucher, invoice, or request for contract financing payment with associated supporting documentation. The payment request must comply with the requirements identified in FAR 32.905(b), ‘‘Content of Invoices’’ and the applicable Payment clause included in this contract.

(b) Except as provided in paragraph (c) of this clause, the Contractor shall submit payment requests electronically using the Department of Treasury Invoice Processing Platform (IPP) or successor system. Information regarding IPP, including IPP Customer Support contact information, is available at www.ipp.gov or any successor site.

(c) The Contractor may submit payment requests using other than IPP only when the Contracting Officer authorizes alternate procedures in writing in accordance with HHS procedures.

(d) If alternate payment procedures are authorized, the Contractor shall include a copy of the Contracting Officer’s written authorization with each payment request.

http://www.ipp.gov/