Attachment 1_SON_Automated Liquid Handler Systems.pdf

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Automated Liquid Handling Systems– Brand Name or Equal
Solicitation number
RFQ-NIAID-24-2224319
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This document is a Request for Quotation (RFQ) for the procurement of two (2) automated liquid handling systems for the National Institute of Allergy and Infectious Diseases (NIAID), Vaccine Production Program (VPP), at the Vaccine Research Center (VRC).

The key requirements are for two automated liquid handling systems - one for early phase purification development microchromatography with biolayer interferometry detection, and one for purification screening and upstream process development microchromatography. The systems must meet detailed technical specifications outlined in the Statement of Needs, including capabilities for microplate handling, liquid chromatography integration, and future expansion. The solicitation is being competed as full and open competition, with brand name or equal considered. Quotes are due by September 23, 2024, with an estimated 65-day delivery timeframe upon award. Awards may be made to up to two responsible vendors, but preference is for a single comprehensive solution. Evaluation will be based on technical acceptability, past performance, and price.

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Statement of Needs (SON) – Automated Liquid Handling Systems

This SON is for the procurement of two instruments/systems capable of the following:

1. Early phase purification development microchromatography liquid handler with biolayer interferometry detection:

In-line integration with biolayer interferometry instruments o Agreement with the manufacturer of the biolayer interferometry instruments to ship a loaner to the awardee to do the integration of the two pieces of equipment.

In-line integration with Tecan Spark spectrophotometers.

Compatible with library of Tecan liquid handling scripts and Tecan Fluent Control.

Compatible with Atoll RoboColumn pressurized microchromatography columns.

Minimum of 8 channel simultaneous pipetting with disposable and fixed tips.

Capacity of up to 1 mL per disposable pipetting channel, up to 0.5 mL fixed.

Programmable gripper capable of eccentric and concentric microplate and tool manipulation.

Capacity for at least 0 SBS/SLAS footprint microplates.

In-line integration with centrifuge capable of >6000 rcf.

Capable of .

Capable of future expansion to include thermostatting for at least two microplates or programmable thermocycler for single microplate.

Facility Requirements:

o Weight: 800 lbs. or less (full loaded) o Space Clearance around instrument

Distance to object in rear of the instrument: 4-6 inches inches

Outreach of the short (open) front safety panel: Maximum of 16 inches Distance to object in front of the instrument: Between 38- inches o Footprint of instrument Fo Overall Depth: 38 inches Overall Length: 85 inches

In-line integration with Tecan Spark spectrophotometers.

Compatible with library of Tecan liquid handling scripts and Tecan fluent control.

Compatible with Atoll RoboColumn pressurized microchromatography columns.

Minimum 8 channel simultaneous pipetting with disposable and fixed tips.

Capacity of up to 1 mL per disposable pipetting channel and up to 0.5 mL fixed.

Programmable gripper capable of eccentric and concentric microplate and tool manipulation.

S footprint microplates.

In-line integration with centrifuge capable of >6000 rcf.

Capable of future expansion to include thermostatting for at least two microplates or programmable thermocycler for single microplate.

Facility Requirements:

o Weight: 800 lbs. or less (full loaded) o Space Clearance around instrument

Distance to object in rear of the instrument: 4-6 inches

Outreach of the short (open) front safety panel: Maximum of 16 inches Distance to object in front of the instrument: Between 38-o Footprint of instrument Footp Overall Depth: 38 inches Overall Length: 65 inches

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