ATTACHMENT 1 -Salient Characteristics Palo Alto.docx
DOCX document 27 KB Posted
- Solicitation number
- 36C77621Q0109
About this file
This document contains a presolicitation notice and federal contract opportunity for the procurement of an Octet RED96e Assay System. The Department of Veterans Affairs Northern California Healthcare System needs to procure the Octet RED96e Assay System, which is a benchtop protein interaction detection system that uses label-free, real-time analysis. Quotes for this brand name only request will be accepted until February 11, 2021. The solicitation will be set aside for small businesses and issued as a request for quotes in accordance with federal acquisition regulations. The Technology Acquisition Center located in Austin, Texas will serve as the contracting agency.
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| File | Type | Posted |
|---|---|---|
| ATTACHMENT 2 - Brand Name Justification and Approval.pdf | ||
| 36C77621Q0109.docx | DOCX document |
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Salient Characteristics
Octet RED96e assay system (Brand name)
General Octet RED96e assay system – for biomolecular detection using label-free, real time analysis. Benchtop protein interaction detection system that is fluidics-free and based on Bio-Layer Interferometry, which can analyze up to 8 samples in parallel for affinity, kinetics or active protein concentration determination from sample in 96-well or 384-well microplates.
Warranty Requirements One-year warranty covering parts and labor.
Features
· Benchtop protein interaction detection system that is fluidics-free and based on Bio-Layer Interferometry.
· Measure 1-8 samples in parallel for affinity, kinetics or protein titer determination for up to maximum sample well capacity of 96 on one walk-away run.
· Affinity or kinetic analyses to include binding constants (kobs, ka, kd, and kD) as a result of protein-protein or protein-small molecule interactions.
· Protein titer determination defied as the concentration of active protein as determined from a standard curve with known concentrations.
· Epitope binnng analysis, to include cross-blocking matrices and trace overlays, can be measured for 8 x 8 pairwise interactions in one walk-away run.
· Compatible with crude samples and is non-destructive allowing full sample recovery and usage without cross-contamination from other running buffers.
· Rapid determination antibody concentration to enable real-time monitoring of protein production. IgG concentration time: 2 minutes for 8 samples, 32 minutes for 96 samples.
· High throughput screening of proteins, antibodies for off-rate and affinity ranking. High resolution kinetic characterization for protein-small molecule interactions, affinity maturation and lead candidate selection.
· Simultaneous comparison of up to 8 different buffer conditions.
· Biosensors are disposable with optional regeneration, re-racking and re-use.
· Biosensor ligand immobilization can take place inside (online) or outside (offline) of the instrument for increased throughput and workflow flexibility.
· Convert ELISA assays into rapid, no-wash one or multiple step assays that maintain assay integrity in the presence of low affinity binding interactions.
· Dynamic range for direct quantitation of human lgG: 0.05-2000 ug/mL.
· Unattended experiment run time is up to 12 hours with the microplate evaporation cover.
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